Sample overview
| Project Name |
TCGA-UVM
|
| GSE ID |
GSE138433
|
| GSM ID |
GSM4107904
|
| Cell Line |
None
|
| Tissue type |
Eye
|
| Disease Type |
Uveal melanoma
|
| PMID |
33462406
|
| Initial gene number |
33694
|
| Initial cell number |
737280
|
| Post-QC gene number |
5119
|
| Post-QC cell number |
1846
|
Bulk-to-ScRNA-seq Label Transfer
Bulk phenotype-associated subpopulations
Reference-Based Annotation
Differentially expressed genes
Overall Survival : Cluster
vs
There are no results of the analysis here
Overall Survival : Cluster
vs ( + )
There are no results of the analysis here
Clinical Stage : Cluster
vs
There
are no results of the analysis here
Tumor Size : Cluster
vs
There
are no results of the analysis here
Lymph Node Involvement : Cluster
vs
There
are no results of the analysis here
Distant Metastasis : Cluster
vs
There
are no results of the analysis here
Cell-Cell communications ( Survival-Associated Subpopulations Across Cell Types )
Cell Population Signaling and Communication
Ligand-Receptor-Mediated Cell-Cell Interactions
| Sending Cell Type |
Ligand |
Receiving Cell Type |
Receptor |
Score |
P-value |
Pathway Name |
Function |
Evidence |
| HSC(Good)_source |
SPP1_ligand |
HSC(Good)_target |
CD44_receptor |
1.054e-02 |
0.0 |
SPP1 |
Secreted Signaling |
PMID: 21907263 |
| HSC(Nos)_source |
SPP1_ligand |
HSC(Good)_target |
CD44_receptor |
2.113e-02 |
0.01 |
SPP1 |
Secreted Signaling |
PMID: 21907263 |
| HSC(Poor)_source |
SPP1_ligand |
HSC(Good)_target |
CD44_receptor |
3.802e-03 |
0.0 |
SPP1 |
Secreted Signaling |
PMID: 21907263 |
| HSC(Good)_source |
SPP1_ligand |
HSC(Nos)_target |
CD44_receptor |
2.209e-02 |
0.0 |
SPP1 |
Secreted Signaling |
PMID: 21907263 |
| HSC(Poor)_source |
SPP1_ligand |
HSC(Nos)_target |
CD44_receptor |
7.972e-03 |
0.0 |
SPP1 |
Secreted Signaling |
PMID: 21907263 |
| CD8+,T-cells(Poor)_source |
PSAP_ligand |
CD8+,T-cells(Poor)_target |
GPR37_receptor |
2.597e-09 |
0.0 |
PSAP |
Secreted Signaling |
PMID: 23690594 |
| Macrophages(Poor)_source |
PSAP_ligand |
CD8+,T-cells(Poor)_target |
GPR37_receptor |
1.863e-09 |
0.0 |
PSAP |
Secreted Signaling |
PMID: 23690594 |
| CD8+,T-cells(Poor)_source |
PSAP_ligand |
HSC(Good)_target |
GPR37_receptor |
1.164e-08 |
0.0 |
PSAP |
Secreted Signaling |
PMID: 23690594 |
| Macrophages(Poor)_source |
PSAP_ligand |
HSC(Good)_target |
GPR37_receptor |
8.352e-09 |
0.0 |
PSAP |
Secreted Signaling |
PMID: 23690594 |
| CD8+,T-cells(Poor)_source |
PSAP_ligand |
HSC(Nos)_target |
GPR37_receptor |
2.636e-08 |
0.0 |
PSAP |
Secreted Signaling |
PMID: 23690594 |
| Macrophages(Poor)_source |
PSAP_ligand |
HSC(Nos)_target |
GPR37_receptor |
1.891e-08 |
0.0 |
PSAP |
Secreted Signaling |
PMID: 23690594 |
| CD8+,T-cells(Poor)_source |
PSAP_ligand |
HSC(Poor)_target |
GPR37_receptor |
3.947e-09 |
0.0 |
PSAP |
Secreted Signaling |
PMID: 23690594 |
| Macrophages(Poor)_source |
PSAP_ligand |
HSC(Poor)_target |
GPR37_receptor |
2.831e-09 |
0.0 |
PSAP |
Secreted Signaling |
PMID: 23690594 |
| CD8+,T-cells(Poor)_source |
PSAP_ligand |
Macrophages(Poor)_target |
GPR37_receptor |
3.227e-10 |
0.01 |
PSAP |
Secreted Signaling |
PMID: 23690594 |
| CD8+,T-cells(Poor)_source |
APP_ligand |
CD8+,T-cells(Poor)_target |
CD74_receptor |
1.148e-08 |
0.0 |
APP |
Cell-Cell Contact |
PMID: 19849849 |
| HSC(Good)_source |
APP_ligand |
CD8+,T-cells(Poor)_target |
CD74_receptor |
5.784e-08 |
0.0 |
APP |
Cell-Cell Contact |
PMID: 19849849 |
| HSC(Nos)_source |
APP_ligand |
CD8+,T-cells(Poor)_target |
CD74_receptor |
1.322e-07 |
0.0 |
APP |
Cell-Cell Contact |
PMID: 19849849 |
| HSC(Poor)_source |
APP_ligand |
CD8+,T-cells(Poor)_target |
CD74_receptor |
1.893e-08 |
0.0 |
APP |
Cell-Cell Contact |
PMID: 19849849 |
| Macrophages(Poor)_source |
APP_ligand |
CD8+,T-cells(Poor)_target |
CD74_receptor |
1.022e-09 |
0.0 |
APP |
Cell-Cell Contact |
PMID: 19849849 |
| CD8+,T-cells(Poor)_source |
APP_ligand |
Macrophages(Poor)_target |
CD74_receptor |
8.186e-09 |
0.0 |
APP |
Cell-Cell Contact |
PMID: 19849849 |
| HSC(Good)_source |
APP_ligand |
Macrophages(Poor)_target |
CD74_receptor |
4.124e-08 |
0.0 |
APP |
Cell-Cell Contact |
PMID: 19849849 |
| HSC(Nos)_source |
APP_ligand |
Macrophages(Poor)_target |
CD74_receptor |
9.429e-08 |
0.0 |
APP |
Cell-Cell Contact |
PMID: 19849849 |
| HSC(Poor)_source |
APP_ligand |
Macrophages(Poor)_target |
CD74_receptor |
1.350e-08 |
0.0 |
APP |
Cell-Cell Contact |
PMID: 19849849 |
| Macrophages(Poor)_source |
APP_ligand |
Macrophages(Poor)_target |
CD74_receptor |
7.290e-10 |
0.0 |
APP |
Cell-Cell Contact |
PMID: 19849849 |
| CD8+,T-cells(Poor)_source |
CD99_ligand |
CD8+,T-cells(Poor)_target |
CD99_receptor |
1.350e-05 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
CDH1_ligand |
HSC(Good)_target |
CDH1_receptor |
1.002e-08 |
0.0 |
CDH |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Good)_source |
CDH1_ligand |
HSC(Nos)_target |
CDH1_receptor |
1.002e-08 |
0.0 |
CDH |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
CDH1_ligand |
HSC(Nos)_target |
CDH1_receptor |
2.140e-08 |
0.0 |
CDH |
Cell-Cell Contact |
KEGG: hsa04514 |