Sample overview
| Project Name |
TCGA-UVM
|
| GSE ID |
GSE138433
|
| GSM ID |
GSM4107903
|
| Cell Line |
None
|
| Tissue type |
Eye
|
| Disease Type |
Uveal melanoma
|
| PMID |
33462406
|
| Initial gene number |
33694
|
| Initial cell number |
737280
|
| Post-QC gene number |
3047
|
| Post-QC cell number |
740
|
Bulk-to-ScRNA-seq Label Transfer
Bulk phenotype-associated subpopulations
Reference-Based Annotation
Differentially expressed genes
Overall Survival : Cluster
vs
There are no results of the analysis here
Overall Survival : Cluster
vs ( + )
There are no results of the analysis here
Clinical Stage : Cluster
vs
There
are no results of the analysis here
Tumor Size : Cluster
vs
There
are no results of the analysis here
Lymph Node Involvement : Cluster
vs
There
are no results of the analysis here
Distant Metastasis : Cluster
vs
There
are no results of the analysis here
Cell-Cell communications ( Survival-Associated Subpopulations Across Cell Types )
Cell Population Signaling and Communication
Ligand-Receptor-Mediated Cell-Cell Interactions
| Sending Cell Type |
Ligand |
Receiving Cell Type |
Receptor |
Score |
P-value |
Pathway Name |
Function |
Evidence |
| HSC(Good)_source |
GRN_ligand |
CD8+,T-cells(Poor)_target |
SORT1_receptor |
2.462e-09 |
0.0 |
GRN |
Secreted Signaling |
PMID: 29555433 |
| HSC(Nos)_source |
GRN_ligand |
CD8+,T-cells(Poor)_target |
SORT1_receptor |
2.438e-09 |
0.0 |
GRN |
Secreted Signaling |
PMID: 29555433 |
| HSC(Good)_source |
GRN_ligand |
Erythrocytes(Good)_target |
SORT1_receptor |
1.068e-08 |
0.0 |
GRN |
Secreted Signaling |
PMID: 29555433 |
| HSC(Nos)_source |
GRN_ligand |
Erythrocytes(Good)_target |
SORT1_receptor |
1.058e-08 |
0.0 |
GRN |
Secreted Signaling |
PMID: 29555433 |
| HSC(Good)_source |
GRN_ligand |
Erythrocytes(Nos)_target |
SORT1_receptor |
1.520e-08 |
0.0 |
GRN |
Secreted Signaling |
PMID: 29555433 |
| HSC(Nos)_source |
GRN_ligand |
Erythrocytes(Nos)_target |
SORT1_receptor |
1.506e-08 |
0.0 |
GRN |
Secreted Signaling |
PMID: 29555433 |
| HSC(Good)_source |
GRN_ligand |
Erythrocytes(Poor)_target |
SORT1_receptor |
2.514e-09 |
0.0 |
GRN |
Secreted Signaling |
PMID: 29555433 |
| HSC(Nos)_source |
GRN_ligand |
Erythrocytes(Poor)_target |
SORT1_receptor |
2.490e-09 |
0.0 |
GRN |
Secreted Signaling |
PMID: 29555433 |
| HSC(Good)_source |
GRN_ligand |
HSC(Good)_target |
SORT1_receptor |
1.055e-06 |
0.0 |
GRN |
Secreted Signaling |
PMID: 29555433 |
| HSC(Nos)_source |
GRN_ligand |
HSC(Good)_target |
SORT1_receptor |
1.045e-06 |
0.0 |
GRN |
Secreted Signaling |
PMID: 29555433 |
| HSC(Good)_source |
GRN_ligand |
HSC(Nos)_target |
SORT1_receptor |
4.689e-07 |
0.0 |
GRN |
Secreted Signaling |
PMID: 29555433 |
| HSC(Nos)_source |
GRN_ligand |
HSC(Nos)_target |
SORT1_receptor |
4.645e-07 |
0.0 |
GRN |
Secreted Signaling |
PMID: 29555433 |
| HSC(Good)_source |
GRN_ligand |
HSC(Poor)_target |
SORT1_receptor |
2.488e-09 |
0.0 |
GRN |
Secreted Signaling |
PMID: 29555433 |
| HSC(Nos)_source |
GRN_ligand |
HSC(Poor)_target |
SORT1_receptor |
2.465e-09 |
0.0 |
GRN |
Secreted Signaling |
PMID: 29555433 |
| HSC(Good)_source |
GRN_ligand |
Macrophages(Nos)_target |
SORT1_receptor |
4.526e-10 |
0.0 |
GRN |
Secreted Signaling |
PMID: 29555433 |
| HSC(Nos)_source |
GRN_ligand |
Macrophages(Nos)_target |
SORT1_receptor |
4.483e-10 |
0.0 |
GRN |
Secreted Signaling |
PMID: 29555433 |
| HSC(Good)_source |
GRN_ligand |
Macrophages(Poor)_target |
SORT1_receptor |
2.122e-09 |
0.0 |
GRN |
Secreted Signaling |
PMID: 29555433 |
| HSC(Nos)_source |
GRN_ligand |
Macrophages(Poor)_target |
SORT1_receptor |
2.102e-09 |
0.0 |
GRN |
Secreted Signaling |
PMID: 29555433 |
| HSC(Good)_source |
GRN_ligand |
Melanocytes(Nos)_target |
SORT1_receptor |
3.901e-09 |
0.0 |
GRN |
Secreted Signaling |
PMID: 29555433 |
| HSC(Nos)_source |
GRN_ligand |
Melanocytes(Nos)_target |
SORT1_receptor |
3.864e-09 |
0.0 |
GRN |
Secreted Signaling |
PMID: 29555433 |
| CD8+,T-cells(Poor)_source |
CD99_ligand |
CD8+,T-cells(Poor)_target |
CD99_receptor |
7.041e-05 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Good)_source |
CD99_ligand |
CD8+,T-cells(Poor)_target |
CD99_receptor |
6.963e-05 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
CD99_ligand |
CD8+,T-cells(Poor)_target |
CD99_receptor |
7.067e-05 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Poor)_source |
CD99_ligand |
HSC(Good)_target |
CD99_receptor |
6.963e-05 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Good)_source |
CD99_ligand |
HSC(Good)_target |
CD99_receptor |
6.199e-05 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
CD99_ligand |
HSC(Good)_target |
CD99_receptor |
6.270e-05 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Poor)_source |
CD99_ligand |
HSC(Nos)_target |
CD99_receptor |
7.067e-05 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Good)_source |
CD99_ligand |
HSC(Nos)_target |
CD99_receptor |
6.270e-05 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
CD99_ligand |
HSC(Nos)_target |
CD99_receptor |
6.341e-05 |
0.01 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Good)_source |
CDH1_ligand |
Erythrocytes(Good)_target |
CDH1_receptor |
1.305e-09 |
0.0 |
CDH |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Good)_source |
CDH1_ligand |
Erythrocytes(Nos)_target |
CDH1_receptor |
1.764e-09 |
0.0 |
CDH |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
CDH1_ligand |
Erythrocytes(Nos)_target |
CDH1_receptor |
1.703e-09 |
0.01 |
CDH |
Cell-Cell Contact |
KEGG: hsa04514 |
| Melanocytes(Nos)_source |
CDH1_ligand |
Erythrocytes(Nos)_target |
CDH1_receptor |
4.073e-10 |
0.01 |
CDH |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Good)_source |
CDH1_ligand |
Erythrocytes(Poor)_target |
CDH1_receptor |
2.932e-10 |
0.01 |
CDH |
Cell-Cell Contact |
KEGG: hsa04514 |
| Melanocytes(Nos)_source |
CDH1_ligand |
Erythrocytes(Poor)_target |
CDH1_receptor |
6.770e-11 |
0.04 |
CDH |
Cell-Cell Contact |
KEGG: hsa04514 |
| Erythrocytes(Good)_source |
CDH1_ligand |
HSC(Good)_target |
CDH1_receptor |
1.305e-09 |
0.0 |
CDH |
Cell-Cell Contact |
KEGG: hsa04514 |
| Erythrocytes(Nos)_source |
CDH1_ligand |
HSC(Good)_target |
CDH1_receptor |
1.764e-09 |
0.0 |
CDH |
Cell-Cell Contact |
KEGG: hsa04514 |
| Erythrocytes(Poor)_source |
CDH1_ligand |
HSC(Good)_target |
CDH1_receptor |
2.932e-10 |
0.01 |
CDH |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Good)_source |
CDH1_ligand |
HSC(Good)_target |
CDH1_receptor |
1.947e-09 |
0.0 |
CDH |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
CDH1_ligand |
HSC(Good)_target |
CDH1_receptor |
1.880e-09 |
0.0 |
CDH |
Cell-Cell Contact |
KEGG: hsa04514 |
| Melanocytes(Nos)_source |
CDH1_ligand |
HSC(Good)_target |
CDH1_receptor |
4.496e-10 |
0.0 |
CDH |
Cell-Cell Contact |
KEGG: hsa04514 |
| Erythrocytes(Nos)_source |
CDH1_ligand |
HSC(Nos)_target |
CDH1_receptor |
1.703e-09 |
0.01 |
CDH |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Good)_source |
CDH1_ligand |
HSC(Nos)_target |
CDH1_receptor |
1.880e-09 |
0.0 |
CDH |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
CDH1_ligand |
HSC(Nos)_target |
CDH1_receptor |
1.815e-09 |
0.0 |
CDH |
Cell-Cell Contact |
KEGG: hsa04514 |
| Melanocytes(Nos)_source |
CDH1_ligand |
HSC(Nos)_target |
CDH1_receptor |
4.341e-10 |
0.0 |
CDH |
Cell-Cell Contact |
KEGG: hsa04514 |
| Erythrocytes(Nos)_source |
CDH1_ligand |
Melanocytes(Nos)_target |
CDH1_receptor |
4.073e-10 |
0.01 |
CDH |
Cell-Cell Contact |
KEGG: hsa04514 |
| Erythrocytes(Poor)_source |
CDH1_ligand |
Melanocytes(Nos)_target |
CDH1_receptor |
6.770e-11 |
0.04 |
CDH |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Good)_source |
CDH1_ligand |
Melanocytes(Nos)_target |
CDH1_receptor |
4.496e-10 |
0.0 |
CDH |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
CDH1_ligand |
Melanocytes(Nos)_target |
CDH1_receptor |
4.341e-10 |
0.0 |
CDH |
Cell-Cell Contact |
KEGG: hsa04514 |
| Melanocytes(Nos)_source |
CDH1_ligand |
Melanocytes(Nos)_target |
CDH1_receptor |
1.038e-10 |
0.01 |
CDH |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Good)_source |
MPZL1_ligand |
CD8+,T-cells(Poor)_target |
MPZL1_receptor |
8.130e-10 |
0.02 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Good)_source |
MPZL1_ligand |
Erythrocytes(Good)_target |
MPZL1_receptor |
2.489e-09 |
0.0 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Good)_source |
MPZL1_ligand |
Erythrocytes(Nos)_target |
MPZL1_receptor |
3.417e-09 |
0.0 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Good)_source |
MPZL1_ligand |
Erythrocytes(Poor)_target |
MPZL1_receptor |
7.225e-10 |
0.0 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Poor)_source |
MPZL1_ligand |
HSC(Good)_target |
MPZL1_receptor |
8.130e-10 |
0.02 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| Erythrocytes(Good)_source |
MPZL1_ligand |
HSC(Good)_target |
MPZL1_receptor |
2.489e-09 |
0.0 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| Erythrocytes(Nos)_source |
MPZL1_ligand |
HSC(Good)_target |
MPZL1_receptor |
3.417e-09 |
0.0 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| Erythrocytes(Poor)_source |
MPZL1_ligand |
HSC(Good)_target |
MPZL1_receptor |
7.225e-10 |
0.0 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Good)_source |
MPZL1_ligand |
HSC(Good)_target |
MPZL1_receptor |
1.346e-06 |
0.0 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
MPZL1_ligand |
HSC(Good)_target |
MPZL1_receptor |
6.712e-08 |
0.0 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Poor)_source |
MPZL1_ligand |
HSC(Good)_target |
MPZL1_receptor |
3.445e-09 |
0.0 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| Macrophages(Poor)_source |
MPZL1_ligand |
HSC(Good)_target |
MPZL1_receptor |
3.084e-10 |
0.02 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| Melanocytes(Nos)_source |
MPZL1_ligand |
HSC(Good)_target |
MPZL1_receptor |
8.851e-09 |
0.0 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Good)_source |
MPZL1_ligand |
HSC(Nos)_target |
MPZL1_receptor |
6.712e-08 |
0.0 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
MPZL1_ligand |
HSC(Nos)_target |
MPZL1_receptor |
3.346e-09 |
0.0 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Poor)_source |
MPZL1_ligand |
HSC(Nos)_target |
MPZL1_receptor |
1.717e-10 |
0.03 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| Melanocytes(Nos)_source |
MPZL1_ligand |
HSC(Nos)_target |
MPZL1_receptor |
4.413e-10 |
0.02 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Good)_source |
MPZL1_ligand |
HSC(Poor)_target |
MPZL1_receptor |
3.445e-09 |
0.0 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
MPZL1_ligand |
HSC(Poor)_target |
MPZL1_receptor |
1.717e-10 |
0.03 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Good)_source |
MPZL1_ligand |
Macrophages(Poor)_target |
MPZL1_receptor |
3.084e-10 |
0.02 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Good)_source |
MPZL1_ligand |
Melanocytes(Nos)_target |
MPZL1_receptor |
8.851e-09 |
0.0 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
MPZL1_ligand |
Melanocytes(Nos)_target |
MPZL1_receptor |
4.413e-10 |
0.02 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |