Sample overview
| Project Name |
TCGA-UVM
|
| GSE ID |
GSE138433
|
| GSM ID |
GSM4107899
|
| Cell Line |
None
|
| Tissue type |
Eye
|
| Disease Type |
Uveal melanoma
|
| PMID |
33462406
|
| Initial gene number |
33694
|
| Initial cell number |
737280
|
| Post-QC gene number |
4789
|
| Post-QC cell number |
1011
|
Bulk-to-ScRNA-seq Label Transfer
Bulk phenotype-associated subpopulations
Reference-Based Annotation
Differentially expressed genes
Overall Survival : Cluster
vs
There are no results of the analysis here
Overall Survival : Cluster
vs ( + )
There are no results of the analysis here
Clinical Stage : Cluster
vs
There
are no results of the analysis here
Tumor Size : Cluster
vs
There
are no results of the analysis here
Lymph Node Involvement : Cluster
vs
There
are no results of the analysis here
Distant Metastasis : Cluster
vs
There
are no results of the analysis here
Cell-Cell communications ( Survival-Associated Subpopulations Across Cell Types )
Cell Population Signaling and Communication
Ligand-Receptor-Mediated Cell-Cell Interactions
| Sending Cell Type |
Ligand |
Receiving Cell Type |
Receptor |
Score |
P-value |
Pathway Name |
Function |
Evidence |
| HSC(Nos)_source |
NAMPT_ligand |
Erythrocytes(Good)_target |
INSR_receptor |
1.906e-07 |
0.01 |
VISFATIN |
Secreted Signaling |
PMID: 28490838 |
| HSC(Nos)_source |
NAMPT_ligand |
Erythrocytes(Nos)_target |
INSR_receptor |
1.612e-07 |
0.01 |
VISFATIN |
Secreted Signaling |
PMID: 28490838 |
| HSC(Nos)_source |
NAMPT_ligand |
Erythrocytes(Poor)_target |
INSR_receptor |
1.644e-07 |
0.01 |
VISFATIN |
Secreted Signaling |
PMID: 28490838 |
| HSC(Nos)_source |
NAMPT_ligand |
HSC(Good)_target |
INSR_receptor |
2.999e-06 |
0.0 |
VISFATIN |
Secreted Signaling |
PMID: 28490838 |
| HSC(Nos)_source |
NAMPT_ligand |
HSC(Nos)_target |
INSR_receptor |
5.810e-06 |
0.0 |
VISFATIN |
Secreted Signaling |
PMID: 28490838 |
| HSC(Nos)_source |
NAMPT_ligand |
HSC(Poor)_target |
INSR_receptor |
1.252e-06 |
0.0 |
VISFATIN |
Secreted Signaling |
PMID: 28490838 |
| HSC(Nos)_source |
MDK_ligand |
HSC(Good)_target |
LRP1_receptor |
1.440e-04 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| HSC(Good)_source |
MDK_ligand |
HSC(Nos)_target |
LRP1_receptor |
1.023e-04 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| HSC(Nos)_source |
MDK_ligand |
HSC(Nos)_target |
LRP1_receptor |
2.972e-04 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| HSC(Nos)_source |
MDK_ligand |
HSC(Poor)_target |
LRP1_receptor |
5.990e-05 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| HSC(Nos)_source |
MDK_ligand |
Erythrocytes(Poor)_target |
NCL_receptor |
2.484e-04 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| HSC(Nos)_source |
MDK_ligand |
HSC(Good)_target |
NCL_receptor |
9.986e-04 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| HSC(Good)_source |
MDK_ligand |
HSC(Nos)_target |
NCL_receptor |
7.828e-04 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| HSC(Nos)_source |
MDK_ligand |
HSC(Nos)_target |
NCL_receptor |
2.256e-03 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| HSC(Good)_source |
GRN_ligand |
HSC(Good)_target |
SORT1_receptor |
2.072e-04 |
0.0 |
GRN |
Secreted Signaling |
PMID: 29555433 |
| HSC(Nos)_source |
GRN_ligand |
HSC(Good)_target |
SORT1_receptor |
4.272e-04 |
0.0 |
GRN |
Secreted Signaling |
PMID: 29555433 |
| HSC(Good)_source |
GRN_ligand |
HSC(Nos)_target |
SORT1_receptor |
3.614e-04 |
0.0 |
GRN |
Secreted Signaling |
PMID: 29555433 |
| HSC(Nos)_source |
GRN_ligand |
HSC(Nos)_target |
SORT1_receptor |
7.451e-04 |
0.0 |
GRN |
Secreted Signaling |
PMID: 29555433 |
| HSC(Poor)_source |
GRN_ligand |
HSC(Nos)_target |
SORT1_receptor |
1.356e-04 |
0.02 |
GRN |
Secreted Signaling |
PMID: 29555433 |
| HSC(Good)_source |
COL6A1_ligand |
Erythrocytes(Good)_target |
CD44_receptor |
3.368e-04 |
0.0 |
COLLAGEN |
ECM-Receptor |
KEGG: hsa04512 |
| HSC(Nos)_source |
COL6A1_ligand |
Erythrocytes(Good)_target |
CD44_receptor |
5.295e-04 |
0.0 |
COLLAGEN |
ECM-Receptor |
KEGG: hsa04512 |
| HSC(Nos)_source |
COL6A1_ligand |
Erythrocytes(Nos)_target |
CD44_receptor |
5.411e-04 |
0.0 |
COLLAGEN |
ECM-Receptor |
KEGG: hsa04512 |
| HSC(Good)_source |
COL6A1_ligand |
HSC(Good)_target |
CD44_receptor |
9.738e-04 |
0.0 |
COLLAGEN |
ECM-Receptor |
KEGG: hsa04512 |
| HSC(Nos)_source |
COL6A1_ligand |
HSC(Good)_target |
CD44_receptor |
1.531e-03 |
0.0 |
COLLAGEN |
ECM-Receptor |
KEGG: hsa04512 |
| HSC(Good)_source |
COL6A1_ligand |
HSC(Nos)_target |
CD44_receptor |
1.379e-03 |
0.0 |
COLLAGEN |
ECM-Receptor |
KEGG: hsa04512 |
| HSC(Nos)_source |
COL6A1_ligand |
HSC(Nos)_target |
CD44_receptor |
2.167e-03 |
0.0 |
COLLAGEN |
ECM-Receptor |
KEGG: hsa04512 |
| HSC(Nos)_source |
COL6A2_ligand |
Erythrocytes(Good)_target |
CD44_receptor |
4.285e-04 |
0.0 |
COLLAGEN |
ECM-Receptor |
KEGG: hsa04512 |
| HSC(Nos)_source |
COL6A2_ligand |
Erythrocytes(Nos)_target |
CD44_receptor |
4.379e-04 |
0.0 |
COLLAGEN |
ECM-Receptor |
KEGG: hsa04512 |
| HSC(Nos)_source |
COL6A2_ligand |
Erythrocytes(Poor)_target |
CD44_receptor |
2.362e-04 |
0.0 |
COLLAGEN |
ECM-Receptor |
KEGG: hsa04512 |
| HSC(Nos)_source |
COL6A2_ligand |
HSC(Good)_target |
CD44_receptor |
1.239e-03 |
0.0 |
COLLAGEN |
ECM-Receptor |
KEGG: hsa04512 |
| HSC(Nos)_source |
COL6A2_ligand |
HSC(Nos)_target |
CD44_receptor |
1.754e-03 |
0.0 |
COLLAGEN |
ECM-Receptor |
KEGG: hsa04512 |
| HSC(Nos)_source |
COL6A2_ligand |
HSC(Poor)_target |
CD44_receptor |
5.353e-04 |
0.0 |
COLLAGEN |
ECM-Receptor |
KEGG: hsa04512 |
| HSC(Nos)_source |
COL9A3_ligand |
Erythrocytes(Good)_target |
CD44_receptor |
3.434e-04 |
0.0 |
COLLAGEN |
ECM-Receptor |
KEGG: hsa04512 |
| HSC(Nos)_source |
COL9A3_ligand |
Erythrocytes(Nos)_target |
CD44_receptor |
3.508e-04 |
0.0 |
COLLAGEN |
ECM-Receptor |
KEGG: hsa04512 |
| HSC(Nos)_source |
COL9A3_ligand |
Erythrocytes(Poor)_target |
CD44_receptor |
1.891e-04 |
0.0 |
COLLAGEN |
ECM-Receptor |
KEGG: hsa04512 |
| HSC(Nos)_source |
COL9A3_ligand |
HSC(Good)_target |
CD44_receptor |
9.933e-04 |
0.0 |
COLLAGEN |
ECM-Receptor |
KEGG: hsa04512 |
| HSC(Nos)_source |
COL9A3_ligand |
HSC(Nos)_target |
CD44_receptor |
1.406e-03 |
0.0 |
COLLAGEN |
ECM-Receptor |
KEGG: hsa04512 |
| HSC(Nos)_source |
COL9A3_ligand |
HSC(Poor)_target |
CD44_receptor |
4.287e-04 |
0.0 |
COLLAGEN |
ECM-Receptor |
KEGG: hsa04512 |
| HSC(Nos)_source |
CD99_ligand |
Erythrocytes(Good)_target |
CD99_receptor |
5.910e-04 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
CD99_ligand |
HSC(Good)_target |
CD99_receptor |
1.200e-03 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Erythrocytes(Good)_source |
CD99_ligand |
HSC(Nos)_target |
CD99_receptor |
5.910e-04 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Good)_source |
CD99_ligand |
HSC(Nos)_target |
CD99_receptor |
1.200e-03 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
CD99_ligand |
HSC(Nos)_target |
CD99_receptor |
4.479e-03 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Poor)_source |
CD99_ligand |
HSC(Nos)_target |
CD99_receptor |
9.356e-04 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
CD99_ligand |
HSC(Poor)_target |
CD99_receptor |
9.356e-04 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
MPZL1_ligand |
HSC(Good)_target |
MPZL1_receptor |
3.682e-05 |
0.0 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Good)_source |
MPZL1_ligand |
HSC(Nos)_target |
MPZL1_receptor |
3.682e-05 |
0.0 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
MPZL1_ligand |
HSC(Nos)_target |
MPZL1_receptor |
6.738e-05 |
0.0 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Poor)_source |
MPZL1_ligand |
HSC(Nos)_target |
MPZL1_receptor |
1.892e-05 |
0.0 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
MPZL1_ligand |
HSC(Poor)_target |
MPZL1_receptor |
1.892e-05 |
0.0 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
PTPRM_ligand |
HSC(Nos)_target |
PTPRM_receptor |
7.582e-05 |
0.0 |
PTPRM |
Cell-Cell Contact |
KEGG: hsa04514 |