Sample overview
| Project Name |
TCGA-UCEC
|
| GSE ID |
GSE212217
|
| GSM ID |
GSM6514132
|
| Cell Line |
None
|
| Tissue type |
Peripheral blood
|
| Disease Type |
MMRd Endometrial Adenocarcinoma
|
| PMID |
36301137
|
| Initial gene number |
36601
|
| Initial cell number |
7307
|
| Post-QC gene number |
5165
|
| Post-QC cell number |
417
|
Bulk-to-ScRNA-seq Label Transfer
Bulk phenotype-associated subpopulations
Reference-Based Annotation
Differentially expressed genes
Overall Survival : Cluster
vs
There are no results of the analysis here
Overall Survival : Cluster
vs ( + )
There are no results of the analysis here
Clinical Stage : Cluster
vs
There
are no results of the analysis here
Tumor Size : Cluster
vs
There
are no results of the analysis here
Lymph Node Involvement : Cluster
vs
There
are no results of the analysis here
Distant Metastasis : Cluster
vs
There
are no results of the analysis here
Cell-Cell communications ( Survival-Associated Subpopulations Across Cell Types )
Cell Population Signaling and Communication
Ligand-Receptor-Mediated Cell-Cell Interactions
| Sending Cell Type |
Ligand |
Receiving Cell Type |
Receptor |
Score |
P-value |
Pathway Name |
Function |
Evidence |
| CD4+,T-cells(Nos)_source |
CD40LG_ligand |
CD4+,T-cells(Good)_target |
ITGAM_ITGB2_receptor |
3.223e-09 |
0.03 |
CD40 |
Secreted Signaling |
PMID: 28676852 |
| CD4+,T-cells(Nos)_source |
CD40LG_ligand |
CD8+,T-cells(Nos)_target |
ITGAM_ITGB2_receptor |
5.856e-09 |
0.0 |
CD40 |
Secreted Signaling |
PMID: 28676852 |
| CD4+,T-cells(Good)_source |
APP_ligand |
CD4+,T-cells(Good)_target |
CD74_receptor |
8.669e-05 |
0.0 |
APP |
Cell-Cell Contact |
PMID: 19849849 |
| CD4+,T-cells(Nos)_source |
APP_ligand |
CD4+,T-cells(Good)_target |
CD74_receptor |
6.259e-05 |
0.0 |
APP |
Cell-Cell Contact |
PMID: 19849849 |
| CD4+,T-cells(Good)_source |
APP_ligand |
CD4+,T-cells(Nos)_target |
CD74_receptor |
5.112e-04 |
0.0 |
APP |
Cell-Cell Contact |
PMID: 19849849 |
| CD4+,T-cells(Good)_source |
APP_ligand |
CD8+,T-cells(Nos)_target |
CD74_receptor |
8.837e-05 |
0.0 |
APP |
Cell-Cell Contact |
PMID: 19849849 |
| CD4+,T-cells(Nos)_source |
CD48_ligand |
CD4+,T-cells(Nos)_target |
CD244_receptor |
1.901e-05 |
0.0 |
CD48 |
Cell-Cell Contact |
PMID: 26697006 |
| CD8+,T-cells(Nos)_source |
CD99_ligand |
CD4+,T-cells(Nos)_target |
CD99_receptor |
8.565e-03 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD4+,T-cells(Nos)_source |
CD99_ligand |
CD8+,T-cells(Nos)_target |
CD99_receptor |
8.565e-03 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
CD99_ligand |
CD8+,T-cells(Nos)_target |
CD99_receptor |
9.076e-04 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD4+,T-cells(Nos)_source |
ICAM2_ligand |
CD8+,T-cells(Nos)_target |
ITGAL_ITGB2_receptor |
6.386e-04 |
0.0 |
ICAM |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD4+,T-cells(Nos)_source |
ICAM2_ligand |
CD8+,T-cells(Nos)_target |
ITGAM_ITGB2_receptor |
1.635e-06 |
0.0 |
ICAM |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD4+,T-cells(Good)_source |
ITGB2_ligand |
CD4+,T-cells(Nos)_target |
ICAM2_receptor |
5.787e-04 |
0.03 |
ITGB2 |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
ITGB2_ligand |
CD4+,T-cells(Nos)_target |
ICAM2_receptor |
1.034e-03 |
0.0 |
ITGB2 |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
HLA-A_ligand |
CD4+,T-cells(Nos)_target |
CD8A_receptor |
1.226e-03 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD4+,T-cells(Good)_source |
HLA-A_ligand |
CD8+,T-cells(Nos)_target |
CD8A_receptor |
2.019e-04 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD4+,T-cells(Nos)_source |
HLA-A_ligand |
CD8+,T-cells(Nos)_target |
CD8A_receptor |
5.753e-03 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
HLA-A_ligand |
CD8+,T-cells(Nos)_target |
CD8A_receptor |
4.373e-04 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
HLA-B_ligand |
CD4+,T-cells(Nos)_target |
CD8A_receptor |
1.342e-03 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD4+,T-cells(Good)_source |
HLA-B_ligand |
CD8+,T-cells(Nos)_target |
CD8A_receptor |
2.719e-04 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD4+,T-cells(Nos)_source |
HLA-B_ligand |
CD8+,T-cells(Nos)_target |
CD8A_receptor |
6.543e-03 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
HLA-B_ligand |
CD8+,T-cells(Nos)_target |
CD8A_receptor |
4.740e-04 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
HLA-C_ligand |
CD4+,T-cells(Good)_target |
CD8A_receptor |
4.948e-05 |
0.02 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
HLA-C_ligand |
CD4+,T-cells(Nos)_target |
CD8A_receptor |
1.296e-03 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD4+,T-cells(Good)_source |
HLA-C_ligand |
CD8+,T-cells(Nos)_target |
CD8A_receptor |
2.379e-04 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD4+,T-cells(Nos)_source |
HLA-C_ligand |
CD8+,T-cells(Nos)_target |
CD8A_receptor |
5.856e-03 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
HLA-C_ligand |
CD8+,T-cells(Nos)_target |
CD8A_receptor |
4.595e-04 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
HLA-E_ligand |
CD4+,T-cells(Nos)_target |
CD8A_receptor |
1.671e-03 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD4+,T-cells(Good)_source |
HLA-E_ligand |
CD8+,T-cells(Nos)_target |
CD8A_receptor |
2.276e-04 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD4+,T-cells(Nos)_source |
HLA-E_ligand |
CD8+,T-cells(Nos)_target |
CD8A_receptor |
7.613e-03 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
HLA-E_ligand |
CD8+,T-cells(Nos)_target |
CD8A_receptor |
5.748e-04 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD4+,T-cells(Good)_source |
HLA-A_ligand |
CD8+,T-cells(Nos)_target |
CD8B_receptor |
9.892e-05 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD4+,T-cells(Nos)_source |
HLA-A_ligand |
CD8+,T-cells(Nos)_target |
CD8B_receptor |
2.841e-03 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
HLA-A_ligand |
CD8+,T-cells(Nos)_target |
CD8B_receptor |
2.177e-04 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD4+,T-cells(Good)_source |
HLA-B_ligand |
CD8+,T-cells(Nos)_target |
CD8B_receptor |
1.357e-04 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD4+,T-cells(Nos)_source |
HLA-B_ligand |
CD8+,T-cells(Nos)_target |
CD8B_receptor |
3.258e-03 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
HLA-B_ligand |
CD8+,T-cells(Nos)_target |
CD8B_receptor |
2.373e-04 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD4+,T-cells(Good)_source |
HLA-C_ligand |
CD8+,T-cells(Nos)_target |
CD8B_receptor |
1.177e-04 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD4+,T-cells(Nos)_source |
HLA-C_ligand |
CD8+,T-cells(Nos)_target |
CD8B_receptor |
2.895e-03 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
HLA-C_ligand |
CD8+,T-cells(Nos)_target |
CD8B_receptor |
2.295e-04 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD4+,T-cells(Good)_source |
HLA-E_ligand |
CD8+,T-cells(Nos)_target |
CD8B_receptor |
1.123e-04 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD4+,T-cells(Nos)_source |
HLA-E_ligand |
CD8+,T-cells(Nos)_target |
CD8B_receptor |
3.836e-03 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
HLA-E_ligand |
CD8+,T-cells(Nos)_target |
CD8B_receptor |
2.926e-04 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD4+,T-cells(Good)_source |
HLA-E_ligand |
CD8+,T-cells(Nos)_target |
KLRK1_receptor |
2.928e-04 |
0.0 |
MHC-I |
Cell-Cell Contact |
PMID: 28484462 |
| CD4+,T-cells(Nos)_source |
HLA-E_ligand |
CD8+,T-cells(Nos)_target |
KLRK1_receptor |
9.682e-03 |
0.0 |
MHC-I |
Cell-Cell Contact |
PMID: 28484462 |
| CD8+,T-cells(Nos)_source |
HLA-E_ligand |
CD8+,T-cells(Nos)_target |
KLRK1_receptor |
7.270e-04 |
0.0 |
MHC-I |
Cell-Cell Contact |
PMID: 28484462 |