Sample overview
| Project Name |
TCGA-READ
|
| GSE ID |
GSE222300
|
| GSM ID |
GSM6919588
|
| Cell Line |
None
|
| Tissue type |
rectal cancer
|
| Disease Type |
rectal cancer
|
| PMID |
37146911
|
| Initial gene number |
27984
|
| Initial cell number |
2845
|
| Post-QC gene number |
3416
|
| Post-QC cell number |
789
|
Bulk-to-ScRNA-seq Label Transfer
Bulk phenotype-associated subpopulations
Reference-Based Annotation
Differentially expressed genes
Overall Survival : Cluster
vs
There are no results of the analysis here
Overall Survival : Cluster
vs ( + )
There are no results of the analysis here
Clinical Stage : Cluster
vs
There
are no results of the analysis here
Tumor Size : Cluster
vs
There
are no results of the analysis here
Lymph Node Involvement : Cluster
vs
There
are no results of the analysis here
Distant Metastasis : Cluster
vs
There
are no results of the analysis here
Cell-Cell communications ( Survival-Associated Subpopulations Across Cell Types )
Cell Population Signaling and Communication
Ligand-Receptor-Mediated Cell-Cell Interactions
| Sending Cell Type |
Ligand |
Receiving Cell Type |
Receptor |
Score |
P-value |
Pathway Name |
Function |
Evidence |
| B-cells(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CXCR4_receptor |
4.696e-05 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| CD8+,T-cells(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CXCR4_receptor |
5.922e-05 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| Erythrocytes(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CXCR4_receptor |
1.887e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| Monocytes(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CXCR4_receptor |
4.780e-05 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| B-cells(Nos)_source |
MIF_ligand |
CD8+,T-cells(Nos)_target |
CD74_CXCR4_receptor |
8.925e-05 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| CD8+,T-cells(Nos)_source |
MIF_ligand |
CD8+,T-cells(Nos)_target |
CD74_CXCR4_receptor |
1.123e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| Erythrocytes(Nos)_source |
MIF_ligand |
CD8+,T-cells(Nos)_target |
CD74_CXCR4_receptor |
3.567e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| Monocytes(Nos)_source |
MIF_ligand |
CD8+,T-cells(Nos)_target |
CD74_CXCR4_receptor |
9.050e-05 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| Erythrocytes(Nos)_source |
MIF_ligand |
Erythrocytes(Nos)_target |
CD74_CXCR4_receptor |
6.516e-05 |
0.04 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| B-cells(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CXCR4_receptor |
6.757e-05 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| CD8+,T-cells(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CXCR4_receptor |
8.497e-05 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| Erythrocytes(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CXCR4_receptor |
2.700e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| Monocytes(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CXCR4_receptor |
6.850e-05 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| B-cells(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CD44_receptor |
4.808e-05 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| CD8+,T-cells(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CD44_receptor |
6.063e-05 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Erythrocytes(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CD44_receptor |
1.931e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Monocytes(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CD44_receptor |
4.893e-05 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| B-cells(Nos)_source |
MIF_ligand |
CD8+,T-cells(Nos)_target |
CD74_CD44_receptor |
7.718e-05 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| CD8+,T-cells(Nos)_source |
MIF_ligand |
CD8+,T-cells(Nos)_target |
CD74_CD44_receptor |
9.715e-05 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Erythrocytes(Nos)_source |
MIF_ligand |
CD8+,T-cells(Nos)_target |
CD74_CD44_receptor |
3.089e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Monocytes(Nos)_source |
MIF_ligand |
CD8+,T-cells(Nos)_target |
CD74_CD44_receptor |
7.834e-05 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| B-cells(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
1.144e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| CD8+,T-cells(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
1.433e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Erythrocytes(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
4.537e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Monocytes(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
1.154e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Neutrophils(Nos)_source |
TNFSF14_ligand |
B-cells(Nos)_target |
TNFRSF14_receptor |
1.508e-05 |
0.03 |
LIGHT |
Secreted Signaling |
KEGG: hsa04060 |
| Monocytes(Nos)_source |
TNFSF14_ligand |
CD8+,T-cells(Nos)_target |
TNFRSF14_receptor |
2.454e-06 |
0.03 |
LIGHT |
Secreted Signaling |
KEGG: hsa04060 |
| Neutrophils(Nos)_source |
TNFSF14_ligand |
CD8+,T-cells(Nos)_target |
TNFRSF14_receptor |
5.194e-05 |
0.0 |
LIGHT |
Secreted Signaling |
KEGG: hsa04060 |
| Monocytes(Nos)_source |
TNFSF14_ligand |
Monocytes(Nos)_target |
TNFRSF14_receptor |
2.829e-06 |
0.01 |
LIGHT |
Secreted Signaling |
KEGG: hsa04060 |
| Neutrophils(Nos)_source |
TNFSF14_ligand |
Monocytes(Nos)_target |
TNFRSF14_receptor |
5.986e-05 |
0.0 |
LIGHT |
Secreted Signaling |
KEGG: hsa04060 |
| Neutrophils(Nos)_source |
TNFSF14_ligand |
Neutrophils(Nos)_target |
TNFRSF14_receptor |
2.622e-04 |
0.0 |
LIGHT |
Secreted Signaling |
KEGG: hsa04060 |
| Monocytes(Nos)_source |
ANXA1_ligand |
Monocytes(Nos)_target |
FPR1_receptor |
1.234e-05 |
0.0 |
ANNEXIN |
Secreted Signaling |
PMID: 23230437 |
| CD8+,T-cells(Nos)_source |
ANXA1_ligand |
Neutrophils(Nos)_target |
FPR1_receptor |
3.327e-04 |
0.0 |
ANNEXIN |
Secreted Signaling |
PMID: 23230437 |
| Monocytes(Nos)_source |
ANXA1_ligand |
Neutrophils(Nos)_target |
FPR1_receptor |
5.754e-04 |
0.0 |
ANNEXIN |
Secreted Signaling |
PMID: 23230437 |
| Neutrophils(Nos)_source |
ANXA1_ligand |
Neutrophils(Nos)_target |
FPR1_receptor |
1.049e-05 |
0.0 |
ANNEXIN |
Secreted Signaling |
PMID: 23230437 |
| Monocytes(Nos)_source |
LGALS9_ligand |
B-cells(Nos)_target |
PTPRC_receptor |
3.633e-06 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| Monocytes(Nos)_source |
LGALS9_ligand |
CD8+,T-cells(Nos)_target |
PTPRC_receptor |
2.728e-05 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| Monocytes(Nos)_source |
LGALS9_ligand |
Monocytes(Nos)_target |
PTPRC_receptor |
4.865e-06 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| Monocytes(Nos)_source |
LGALS9_ligand |
Neutrophils(Nos)_target |
PTPRC_receptor |
6.029e-05 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| Monocytes(Nos)_source |
LGALS9_ligand |
B-cells(Nos)_target |
CD44_receptor |
3.500e-06 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| Monocytes(Nos)_source |
LGALS9_ligand |
CD8+,T-cells(Nos)_target |
CD44_receptor |
9.952e-06 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| Monocytes(Nos)_source |
LGALS9_ligand |
Erythrocytes(Nos)_target |
CD44_receptor |
2.336e-08 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| Monocytes(Nos)_source |
LGALS9_ligand |
Monocytes(Nos)_target |
CD44_receptor |
1.324e-05 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| Monocytes(Nos)_source |
LGALS9_ligand |
Neutrophils(Nos)_target |
CD44_receptor |
3.798e-05 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| B-cells(Nos)_source |
CD99_ligand |
B-cells(Nos)_target |
CD99_receptor |
1.364e-05 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
CD99_ligand |
B-cells(Nos)_target |
CD99_receptor |
6.250e-05 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
CD99_ligand |
B-cells(Nos)_target |
CD99_receptor |
3.169e-05 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Nos)_source |
CD99_ligand |
CD8+,T-cells(Nos)_target |
CD99_receptor |
6.250e-05 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
CD99_ligand |
CD8+,T-cells(Nos)_target |
CD99_receptor |
2.765e-04 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
CD99_ligand |
CD8+,T-cells(Nos)_target |
CD99_receptor |
1.421e-04 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Nos)_source |
CD99_ligand |
Monocytes(Nos)_target |
CD99_receptor |
3.169e-05 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
CD99_ligand |
Monocytes(Nos)_target |
CD99_receptor |
1.421e-04 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
CD99_ligand |
Monocytes(Nos)_target |
CD99_receptor |
7.265e-05 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
ICAM1_ligand |
CD8+,T-cells(Nos)_target |
ITGAX_ITGB2_receptor |
3.203e-05 |
0.0 |
ICAM |
Cell-Cell Contact |
PMID: 16252253 |
| Neutrophils(Nos)_source |
ICAM1_ligand |
CD8+,T-cells(Nos)_target |
ITGAX_ITGB2_receptor |
4.596e-04 |
0.0 |
ICAM |
Cell-Cell Contact |
PMID: 16252253 |
| Monocytes(Nos)_source |
ICAM1_ligand |
Monocytes(Nos)_target |
ITGAX_ITGB2_receptor |
5.536e-05 |
0.0 |
ICAM |
Cell-Cell Contact |
PMID: 16252253 |
| Neutrophils(Nos)_source |
ICAM1_ligand |
Monocytes(Nos)_target |
ITGAX_ITGB2_receptor |
7.925e-04 |
0.0 |
ICAM |
Cell-Cell Contact |
PMID: 16252253 |
| Monocytes(Nos)_source |
ICAM1_ligand |
Neutrophils(Nos)_target |
ITGAX_ITGB2_receptor |
2.562e-04 |
0.01 |
ICAM |
Cell-Cell Contact |
PMID: 16252253 |
| Neutrophils(Nos)_source |
ICAM1_ligand |
Neutrophils(Nos)_target |
ITGAX_ITGB2_receptor |
3.678e-03 |
0.0 |
ICAM |
Cell-Cell Contact |
PMID: 16252253 |
| Monocytes(Nos)_source |
ICAM1_ligand |
CD8+,T-cells(Nos)_target |
ITGAL_ITGB2_receptor |
2.463e-05 |
0.0 |
ICAM |
Cell-Cell Contact |
KEGG: hsa04514 |
| Neutrophils(Nos)_source |
ICAM1_ligand |
CD8+,T-cells(Nos)_target |
ITGAL_ITGB2_receptor |
3.536e-04 |
0.0 |
ICAM |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
ICAM1_ligand |
Monocytes(Nos)_target |
ITGAL_ITGB2_receptor |
2.709e-05 |
0.0 |
ICAM |
Cell-Cell Contact |
KEGG: hsa04514 |
| Neutrophils(Nos)_source |
ICAM1_ligand |
Monocytes(Nos)_target |
ITGAL_ITGB2_receptor |
3.887e-04 |
0.0 |
ICAM |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
ICAM1_ligand |
Neutrophils(Nos)_target |
ITGAL_ITGB2_receptor |
1.844e-04 |
0.0 |
ICAM |
Cell-Cell Contact |
KEGG: hsa04514 |
| Neutrophils(Nos)_source |
ICAM1_ligand |
Neutrophils(Nos)_target |
ITGAL_ITGB2_receptor |
2.647e-03 |
0.0 |
ICAM |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
ICAM1_ligand |
CD8+,T-cells(Nos)_target |
ITGAL_receptor |
1.510e-05 |
0.01 |
ICAM |
Cell-Cell Contact |
PMID: 23602662 |
| Neutrophils(Nos)_source |
ICAM1_ligand |
CD8+,T-cells(Nos)_target |
ITGAL_receptor |
2.169e-04 |
0.0 |
ICAM |
Cell-Cell Contact |
PMID: 23602662 |
| Neutrophils(Nos)_source |
ICAM1_ligand |
Monocytes(Nos)_target |
ITGAL_receptor |
1.875e-04 |
0.0 |
ICAM |
Cell-Cell Contact |
PMID: 23602662 |
| Monocytes(Nos)_source |
ICAM1_ligand |
Neutrophils(Nos)_target |
ITGAL_receptor |
1.717e-04 |
0.0 |
ICAM |
Cell-Cell Contact |
PMID: 23602662 |
| Neutrophils(Nos)_source |
ICAM1_ligand |
Neutrophils(Nos)_target |
ITGAL_receptor |
2.466e-03 |
0.0 |
ICAM |
Cell-Cell Contact |
PMID: 23602662 |
| Neutrophils(Nos)_source |
ICAM1_ligand |
B-cells(Nos)_target |
SPN_receptor |
1.306e-08 |
0.0 |
ICAM |
Cell-Cell Contact |
PMID: 1683685 |
| B-cells(Nos)_source |
ICAM1_ligand |
CD8+,T-cells(Nos)_target |
SPN_receptor |
1.262e-06 |
0.0 |
ICAM |
Cell-Cell Contact |
PMID: 1683685 |
| CD8+,T-cells(Nos)_source |
ICAM1_ligand |
CD8+,T-cells(Nos)_target |
SPN_receptor |
1.863e-06 |
0.0 |
ICAM |
Cell-Cell Contact |
PMID: 1683685 |
| Erythrocytes(Nos)_source |
ICAM1_ligand |
CD8+,T-cells(Nos)_target |
SPN_receptor |
1.437e-06 |
0.0 |
ICAM |
Cell-Cell Contact |
PMID: 1683685 |
| Monocytes(Nos)_source |
ICAM1_ligand |
CD8+,T-cells(Nos)_target |
SPN_receptor |
9.669e-06 |
0.0 |
ICAM |
Cell-Cell Contact |
PMID: 1683685 |
| Neutrophils(Nos)_source |
ICAM1_ligand |
CD8+,T-cells(Nos)_target |
SPN_receptor |
1.389e-04 |
0.0 |
ICAM |
Cell-Cell Contact |
PMID: 1683685 |
| Neutrophils(Nos)_source |
ICAM1_ligand |
Erythrocytes(Nos)_target |
SPN_receptor |
2.590e-08 |
0.0 |
ICAM |
Cell-Cell Contact |
PMID: 1683685 |
| Monocytes(Nos)_source |
ICAM1_ligand |
Monocytes(Nos)_target |
SPN_receptor |
1.665e-09 |
0.0 |
ICAM |
Cell-Cell Contact |
PMID: 1683685 |
| Neutrophils(Nos)_source |
ICAM1_ligand |
Monocytes(Nos)_target |
SPN_receptor |
2.394e-08 |
0.0 |
ICAM |
Cell-Cell Contact |
PMID: 1683685 |
| Neutrophils(Nos)_source |
ICAM1_ligand |
Neutrophils(Nos)_target |
SPN_receptor |
1.432e-07 |
0.0 |
ICAM |
Cell-Cell Contact |
PMID: 1683685 |
| CD8+,T-cells(Nos)_source |
ITGB2_ligand |
Monocytes(Nos)_target |
ICAM1_receptor |
4.012e-05 |
0.0 |
ITGB2 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
ITGB2_ligand |
Monocytes(Nos)_target |
ICAM1_receptor |
5.591e-05 |
0.0 |
ITGB2 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Neutrophils(Nos)_source |
ITGB2_ligand |
Monocytes(Nos)_target |
ICAM1_receptor |
1.980e-04 |
0.01 |
ITGB2 |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
ITGB2_ligand |
Neutrophils(Nos)_target |
ICAM1_receptor |
5.754e-04 |
0.0 |
ITGB2 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
ITGB2_ligand |
Neutrophils(Nos)_target |
ICAM1_receptor |
8.003e-04 |
0.0 |
ITGB2 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Neutrophils(Nos)_source |
ITGB2_ligand |
Neutrophils(Nos)_target |
ICAM1_receptor |
2.842e-03 |
0.0 |
ITGB2 |
Cell-Cell Contact |
KEGG: hsa04514 |