Sample overview
| Project Name |
TCGA-READ
|
| GSE ID |
GSE205506
|
| GSM ID |
GSM6213972
|
| Cell Line |
None
|
| Tissue type |
colon
|
| Disease Type |
tumor
|
| PMID |
37172580
|
| Initial gene number |
33538
|
| Initial cell number |
4826
|
| Post-QC gene number |
9083
|
| Post-QC cell number |
122
|
Bulk-to-ScRNA-seq Label Transfer
Bulk phenotype-associated subpopulations
Reference-Based Annotation
Differentially expressed genes
Overall Survival : Cluster
vs
There are no results of the analysis here
Overall Survival : Cluster
vs ( + )
There are no results of the analysis here
Clinical Stage : Cluster
vs
There
are no results of the analysis here
Tumor Size : Cluster
vs
There
are no results of the analysis here
Lymph Node Involvement : Cluster
vs
There
are no results of the analysis here
Distant Metastasis : Cluster
vs
There
are no results of the analysis here
Cell-Cell communications ( Survival-Associated Subpopulations Across Cell Types )
Cell Population Signaling and Communication
Ligand-Receptor-Mediated Cell-Cell Interactions
| Sending Cell Type |
Ligand |
Receiving Cell Type |
Receptor |
Score |
P-value |
Pathway Name |
Function |
Evidence |
| Monocytes(Nos)_source |
IL7_ligand |
B-cells(Nos)_target |
IL7R_IL2RG_receptor |
9.555e-06 |
0.0 |
IL2 |
Secreted Signaling |
KEGG: hsa04060 |
| B-cells(Nos)_source |
IL7_ligand |
Monocytes(Nos)_target |
IL7R_IL2RG_receptor |
5.327e-06 |
0.03 |
IL2 |
Secreted Signaling |
KEGG: hsa04060 |
| Monocytes(Nos)_source |
IL7_ligand |
Monocytes(Nos)_target |
IL7R_IL2RG_receptor |
7.012e-06 |
0.02 |
IL2 |
Secreted Signaling |
KEGG: hsa04060 |
| Monocytes(Nos)_source |
TNFSF10_ligand |
B-cells(Nos)_target |
TNFRSF10A_receptor |
6.396e-07 |
0.01 |
TRAIL |
Secreted Signaling |
KEGG: hsa04060 |
| B-cells(Nos)_source |
TNFSF10_ligand |
Monocytes(Nos)_target |
TNFRSF10A_receptor |
9.322e-08 |
0.0 |
TRAIL |
Secreted Signaling |
KEGG: hsa04060 |
| Monocytes(Nos)_source |
TNFSF10_ligand |
Monocytes(Nos)_target |
TNFRSF10A_receptor |
2.546e-05 |
0.0 |
TRAIL |
Secreted Signaling |
KEGG: hsa04060 |
| Monocytes(Nos)_source |
NAMPT_ligand |
Monocytes(Nos)_target |
INSR_receptor |
8.037e-06 |
0.0 |
VISFATIN |
Secreted Signaling |
PMID: 28490838 |
| Monocytes(Nos)_source |
MDK_ligand |
Monocytes(Nos)_target |
SDC4_receptor |
1.549e-04 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| Monocytes(Nos)_source |
MDK_ligand |
Monocytes(Nos)_target |
ITGA6_ITGB1_receptor |
4.089e-04 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| Monocytes(Nos)_source |
MDK_ligand |
Monocytes(Nos)_target |
LRP1_receptor |
5.768e-05 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| Monocytes(Nos)_source |
MDK_ligand |
Monocytes(Nos)_target |
NCL_receptor |
8.200e-04 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| Monocytes(Nos)_source |
PRSS3_ligand |
B-cells(Nos)_target |
PARD3_receptor |
1.927e-07 |
0.0 |
PARs |
Secreted Signaling |
KEGG: hsa04080 |
| B-cells(Nos)_source |
PRSS3_ligand |
Monocytes(Nos)_target |
PARD3_receptor |
8.843e-08 |
0.0 |
PARs |
Secreted Signaling |
KEGG: hsa04080 |
| Monocytes(Nos)_source |
PRSS3_ligand |
Monocytes(Nos)_target |
PARD3_receptor |
3.418e-04 |
0.0 |
PARs |
Secreted Signaling |
KEGG: hsa04080 |
| Monocytes(Nos)_source |
SEMA3C_ligand |
B-cells(Nos)_target |
NRP1_PLXNA2_receptor |
5.538e-07 |
0.0 |
SEMA3 |
Secreted Signaling |
PMID: 27533782 |
| Monocytes(Nos)_source |
SEMA3C_ligand |
Monocytes(Nos)_target |
NRP1_PLXNA2_receptor |
1.866e-05 |
0.0 |
SEMA3 |
Secreted Signaling |
PMID: 27533782 |
| Monocytes(Nos)_source |
SEMA3C_ligand |
B-cells(Nos)_target |
NRP2_PLXNA2_receptor |
1.885e-06 |
0.0 |
SEMA3 |
Secreted Signaling |
PMID: 27533782 |
| Monocytes(Nos)_source |
SEMA3C_ligand |
Monocytes(Nos)_target |
NRP2_PLXNA2_receptor |
6.894e-06 |
0.0 |
SEMA3 |
Secreted Signaling |
PMID: 27533782 |
| B-cells(Nos)_source |
GRN_ligand |
Monocytes(Nos)_target |
SORT1_receptor |
2.517e-05 |
0.0 |
GRN |
Secreted Signaling |
PMID: 29555433 |
| Monocytes(Nos)_source |
GRN_ligand |
Monocytes(Nos)_target |
SORT1_receptor |
6.055e-05 |
0.0 |
GRN |
Secreted Signaling |
PMID: 29555433 |
| Monocytes(Nos)_source |
LAMB3_ligand |
B-cells(Nos)_target |
ITGA1_ITGB1_receptor |
1.790e-05 |
0.0 |
LAMININ |
ECM-Receptor |
KEGG: hsa04512 |
| Monocytes(Nos)_source |
LAMB3_ligand |
Monocytes(Nos)_target |
ITGA1_ITGB1_receptor |
4.070e-05 |
0.0 |
LAMININ |
ECM-Receptor |
KEGG: hsa04512 |
| Monocytes(Nos)_source |
LAMB3_ligand |
B-cells(Nos)_target |
ITGA2_ITGB1_receptor |
1.790e-05 |
0.0 |
LAMININ |
ECM-Receptor |
KEGG: hsa04512 |
| Monocytes(Nos)_source |
LAMB3_ligand |
Monocytes(Nos)_target |
ITGA2_ITGB1_receptor |
4.054e-05 |
0.0 |
LAMININ |
ECM-Receptor |
KEGG: hsa04512 |
| Monocytes(Nos)_source |
LAMB3_ligand |
Monocytes(Nos)_target |
ITGA3_ITGB1_receptor |
5.177e-05 |
0.0 |
LAMININ |
ECM-Receptor |
KEGG: hsa04512 |
| B-cells(Nos)_source |
THBS1_ligand |
Monocytes(Nos)_target |
ITGA3_ITGB1_receptor |
2.251e-07 |
0.02 |
THBS |
ECM-Receptor |
KEGG: hsa04512 |
| Monocytes(Nos)_source |
THBS1_ligand |
Monocytes(Nos)_target |
ITGA3_ITGB1_receptor |
3.171e-05 |
0.0 |
THBS |
ECM-Receptor |
KEGG: hsa04512 |
| Monocytes(Nos)_source |
LAMB3_ligand |
B-cells(Nos)_target |
ITGA6_ITGB1_receptor |
2.940e-05 |
0.0 |
LAMININ |
ECM-Receptor |
KEGG: hsa04512 |
| Monocytes(Nos)_source |
LAMB3_ligand |
Monocytes(Nos)_target |
ITGA6_ITGB1_receptor |
8.184e-05 |
0.0 |
LAMININ |
ECM-Receptor |
KEGG: hsa04512 |
| Monocytes(Nos)_source |
LAMB3_ligand |
B-cells(Nos)_target |
ITGA6_ITGB4_receptor |
1.578e-05 |
0.0 |
LAMININ |
ECM-Receptor |
KEGG: hsa04512 |
| Monocytes(Nos)_source |
LAMB3_ligand |
Monocytes(Nos)_target |
ITGA6_ITGB4_receptor |
8.754e-05 |
0.0 |
LAMININ |
ECM-Receptor |
KEGG: hsa04512 |
| B-cells(Nos)_source |
THBS1_ligand |
Monocytes(Nos)_target |
SDC4_receptor |
1.346e-07 |
0.0 |
THBS |
ECM-Receptor |
KEGG: hsa04512 |
| Monocytes(Nos)_source |
THBS1_ligand |
Monocytes(Nos)_target |
SDC4_receptor |
1.896e-05 |
0.0 |
THBS |
ECM-Receptor |
KEGG: hsa04512 |
| Monocytes(Nos)_source |
ADGRE5_ligand |
B-cells(Nos)_target |
CD55_receptor |
1.107e-04 |
0.0 |
ADGRE5 |
Cell-Cell Contact |
PMID: 11297558 |
| Monocytes(Nos)_source |
ADGRE5_ligand |
Monocytes(Nos)_target |
CD55_receptor |
1.675e-04 |
0.0 |
ADGRE5 |
Cell-Cell Contact |
PMID: 11297558 |
| Monocytes(Nos)_source |
CD46_ligand |
B-cells(Nos)_target |
JAG1_receptor |
3.913e-07 |
0.01 |
CD46 |
Cell-Cell Contact |
PMID: 23086448 |
| B-cells(Nos)_source |
CD46_ligand |
Monocytes(Nos)_target |
JAG1_receptor |
5.001e-06 |
0.0 |
CD46 |
Cell-Cell Contact |
PMID: 23086448 |
| Monocytes(Nos)_source |
CD46_ligand |
Monocytes(Nos)_target |
JAG1_receptor |
3.676e-05 |
0.0 |
CD46 |
Cell-Cell Contact |
PMID: 23086448 |
| Monocytes(Nos)_source |
CD99_ligand |
B-cells(Nos)_target |
CD99_receptor |
5.159e-04 |
0.03 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Nos)_source |
CD99_ligand |
Monocytes(Nos)_target |
CD99_receptor |
5.159e-04 |
0.03 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
CD99_ligand |
Monocytes(Nos)_target |
CD99_receptor |
1.053e-03 |
0.02 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
CDH1_ligand |
B-cells(Nos)_target |
CDH1_receptor |
3.249e-07 |
0.0 |
CDH |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Nos)_source |
CDH1_ligand |
Monocytes(Nos)_target |
CDH1_receptor |
3.249e-07 |
0.0 |
CDH |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
CDH1_ligand |
Monocytes(Nos)_target |
CDH1_receptor |
1.100e-04 |
0.0 |
CDH |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
CDH1_ligand |
B-cells(Nos)_target |
ITGA2_ITGB1_receptor |
5.565e-05 |
0.0 |
CDH1 |
Cell-Cell Contact |
PMID: 12392763 |
| Monocytes(Nos)_source |
CDH1_ligand |
Monocytes(Nos)_target |
ITGA2_ITGB1_receptor |
1.260e-04 |
0.0 |
CDH1 |
Cell-Cell Contact |
PMID: 12392763 |
| B-cells(Nos)_source |
CD8A_ligand |
Monocytes(Nos)_target |
CEACAM5_receptor |
9.214e-04 |
0.0 |
CEACAM |
Cell-Cell Contact |
PMID: 24104458 |
| Monocytes(Nos)_source |
CD8A_ligand |
Monocytes(Nos)_target |
CEACAM5_receptor |
9.854e-04 |
0.0 |
CEACAM |
Cell-Cell Contact |
PMID: 24104458 |
| Monocytes(Nos)_source |
DSC2_ligand |
Monocytes(Nos)_target |
DSG2_receptor |
7.610e-04 |
0.0 |
DESMOSOME |
Cell-Cell Contact |
PMID: 27298358 |
| Monocytes(Nos)_source |
EFNA1_ligand |
B-cells(Nos)_target |
EPHA2_receptor |
1.687e-08 |
0.0 |
EPHA |
Cell-Cell Contact |
PMID: 15114347 |
| B-cells(Nos)_source |
EFNA1_ligand |
Monocytes(Nos)_target |
EPHA2_receptor |
2.084e-09 |
0.0 |
EPHA |
Cell-Cell Contact |
PMID: 15114347 |
| Monocytes(Nos)_source |
EFNA1_ligand |
Monocytes(Nos)_target |
EPHA2_receptor |
5.134e-07 |
0.0 |
EPHA |
Cell-Cell Contact |
PMID: 15114347 |
| Monocytes(Nos)_source |
EFNA4_ligand |
B-cells(Nos)_target |
EPHA2_receptor |
1.221e-08 |
0.0 |
EPHA |
Cell-Cell Contact |
PMID: 15114347 |
| B-cells(Nos)_source |
EFNA4_ligand |
Monocytes(Nos)_target |
EPHA2_receptor |
3.833e-09 |
0.0 |
EPHA |
Cell-Cell Contact |
PMID: 15114347 |
| Monocytes(Nos)_source |
EFNA4_ligand |
Monocytes(Nos)_target |
EPHA2_receptor |
3.718e-07 |
0.0 |
EPHA |
Cell-Cell Contact |
PMID: 15114347 |
| Monocytes(Nos)_source |
EFNB1_ligand |
B-cells(Nos)_target |
EPHB2_receptor |
1.058e-06 |
0.0 |
EPHB |
Cell-Cell Contact |
PMID: 15114347 |
| Monocytes(Nos)_source |
EFNB1_ligand |
Monocytes(Nos)_target |
EPHB2_receptor |
8.534e-06 |
0.0 |
EPHB |
Cell-Cell Contact |
PMID: 15114347 |
| Monocytes(Nos)_source |
EFNB2_ligand |
B-cells(Nos)_target |
EPHB2_receptor |
1.181e-06 |
0.01 |
EPHB |
Cell-Cell Contact |
PMID: 15114347 |
| Monocytes(Nos)_source |
EFNB2_ligand |
Monocytes(Nos)_target |
EPHB2_receptor |
9.530e-06 |
0.0 |
EPHB |
Cell-Cell Contact |
PMID: 15114347 |
| Monocytes(Nos)_source |
F11R_ligand |
Monocytes(Nos)_target |
F11R_receptor |
2.125e-05 |
0.0 |
JAM |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
HLA-A_ligand |
B-cells(Nos)_target |
CD8A_receptor |
1.769e-03 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
HLA-A_ligand |
Monocytes(Nos)_target |
CD8A_receptor |
1.884e-03 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Nos)_source |
HLA-B_ligand |
Monocytes(Nos)_target |
CD8A_receptor |
2.515e-03 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
HLA-B_ligand |
Monocytes(Nos)_target |
CD8A_receptor |
1.829e-03 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Nos)_source |
HLA-C_ligand |
Monocytes(Nos)_target |
CD8A_receptor |
2.345e-03 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
HLA-C_ligand |
Monocytes(Nos)_target |
CD8A_receptor |
1.563e-03 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
HLA-E_ligand |
B-cells(Nos)_target |
CD8A_receptor |
1.645e-03 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Nos)_source |
HLA-E_ligand |
Monocytes(Nos)_target |
CD8A_receptor |
1.461e-03 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
HLA-E_ligand |
Monocytes(Nos)_target |
CD8A_receptor |
1.753e-03 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
HLA-F_ligand |
B-cells(Nos)_target |
CD8A_receptor |
1.139e-03 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
HLA-F_ligand |
Monocytes(Nos)_target |
CD8A_receptor |
1.217e-03 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
MPZL1_ligand |
B-cells(Nos)_target |
MPZL1_receptor |
2.301e-06 |
0.02 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Nos)_source |
MPZL1_ligand |
Monocytes(Nos)_target |
MPZL1_receptor |
2.301e-06 |
0.02 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
MPZL1_ligand |
Monocytes(Nos)_target |
MPZL1_receptor |
4.140e-05 |
0.0 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
JAG1_ligand |
B-cells(Nos)_target |
NOTCH1_receptor |
2.206e-07 |
0.0 |
NOTCH |
Cell-Cell Contact |
PMID: 22353464 |
| B-cells(Nos)_source |
JAG1_ligand |
Monocytes(Nos)_target |
NOTCH1_receptor |
9.997e-09 |
0.0 |
NOTCH |
Cell-Cell Contact |
PMID: 22353464 |
| Monocytes(Nos)_source |
JAG1_ligand |
Monocytes(Nos)_target |
NOTCH1_receptor |
9.393e-07 |
0.0 |
NOTCH |
Cell-Cell Contact |
PMID: 22353464 |
| Monocytes(Nos)_source |
OCLN_ligand |
B-cells(Nos)_target |
OCLN_receptor |
6.169e-09 |
0.0 |
OCLN |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Nos)_source |
OCLN_ligand |
Monocytes(Nos)_target |
OCLN_receptor |
6.169e-09 |
0.0 |
OCLN |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
OCLN_ligand |
Monocytes(Nos)_target |
OCLN_receptor |
2.335e-08 |
0.0 |
OCLN |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Nos)_source |
PECAM1_ligand |
B-cells(Nos)_target |
PECAM1_receptor |
5.117e-04 |
0.0 |
PECAM1 |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Nos)_source |
SEMA4D_ligand |
Monocytes(Nos)_target |
PLXNB1_receptor |
3.324e-06 |
0.0 |
SEMA4 |
Cell-Cell Contact |
PMID: 27533782 |
| Monocytes(Nos)_source |
SEMA4D_ligand |
Monocytes(Nos)_target |
PLXNB1_receptor |
3.475e-06 |
0.0 |
SEMA4 |
Cell-Cell Contact |
PMID: 27533782 |
| B-cells(Nos)_source |
SEMA4D_ligand |
Monocytes(Nos)_target |
PLXNB2_receptor |
1.651e-05 |
0.01 |
SEMA4 |
Cell-Cell Contact |
PMID: 27533782 |
| Monocytes(Nos)_source |
SEMA4D_ligand |
Monocytes(Nos)_target |
PLXNB2_receptor |
1.726e-05 |
0.0 |
SEMA4 |
Cell-Cell Contact |
PMID: 27533782 |
| Monocytes(Nos)_source |
SEMA6A_ligand |
B-cells(Nos)_target |
PLXNA2_receptor |
7.682e-07 |
0.0 |
SEMA6 |
Cell-Cell Contact |
PMID: 27533782 |
| Monocytes(Nos)_source |
SEMA6A_ligand |
Monocytes(Nos)_target |
PLXNA2_receptor |
1.515e-05 |
0.0 |
SEMA6 |
Cell-Cell Contact |
PMID: 27533782 |