Sample overview
| Project Name |
TCGA-READ
|
| GSE ID |
GSE199726
|
| GSM ID |
GSM5983202
|
| Cell Line |
None
|
| Tissue type |
metastasis: Liver Metastasis
|
| Disease Type |
Sigmoid colon cancer with liver metastasis
|
| PMID |
36805487
|
| Initial gene number |
33694
|
| Initial cell number |
16311
|
| Post-QC gene number |
11541
|
| Post-QC cell number |
497
|
Bulk-to-ScRNA-seq Label Transfer
Bulk phenotype-associated subpopulations
Reference-Based Annotation
Differentially expressed genes
Overall Survival : Cluster
vs
There are no results of the analysis here
Overall Survival : Cluster
vs ( + )
There are no results of the analysis here
Clinical Stage : Cluster
vs
There
are no results of the analysis here
Tumor Size : Cluster
vs
There
are no results of the analysis here
Lymph Node Involvement : Cluster
vs
There
are no results of the analysis here
Distant Metastasis : Cluster
vs
There
are no results of the analysis here
Cell-Cell communications ( Survival-Associated Subpopulations Across Cell Types )
Cell Population Signaling and Communication
Ligand-Receptor-Mediated Cell-Cell Interactions
| Sending Cell Type |
Ligand |
Receiving Cell Type |
Receptor |
Score |
P-value |
Pathway Name |
Function |
Evidence |
| Fibroblasts(Good)_source |
TGFB1_ligand |
Fibroblasts(Nos)_target |
ACVR1_TGFbR_receptor |
1.401e-04 |
0.01 |
TGFb |
Secreted Signaling |
PMID: 29376829 |
| Fibroblasts(Nos)_source |
TGFB1_ligand |
Fibroblasts(Nos)_target |
ACVR1_TGFbR_receptor |
3.500e-04 |
0.0 |
TGFb |
Secreted Signaling |
PMID: 29376829 |
| Fibroblasts(Nos)_source |
PRSS3_ligand |
Fibroblasts(Nos)_target |
F2R_receptor |
4.960e-07 |
0.0 |
PARs |
Secreted Signaling |
KEGG: hsa04080 |
| Fibroblasts(Nos)_source |
COL1A1_ligand |
Fibroblasts(Nos)_target |
CD44_receptor |
2.831e-02 |
0.0 |
COLLAGEN |
ECM-Receptor |
KEGG: hsa04512 |
| Fibroblasts(Nos)_source |
COL1A2_ligand |
Fibroblasts(Nos)_target |
CD44_receptor |
3.290e-02 |
0.0 |
COLLAGEN |
ECM-Receptor |
KEGG: hsa04512 |
| Fibroblasts(Nos)_source |
COL4A1_ligand |
Fibroblasts(Nos)_target |
CD44_receptor |
5.435e-03 |
0.0 |
COLLAGEN |
ECM-Receptor |
KEGG: hsa04512 |
| Fibroblasts(Nos)_source |
COL4A2_ligand |
Fibroblasts(Nos)_target |
CD44_receptor |
6.695e-03 |
0.0 |
COLLAGEN |
ECM-Receptor |
KEGG: hsa04512 |
| Fibroblasts(Nos)_source |
COL6A1_ligand |
Fibroblasts(Nos)_target |
CD44_receptor |
2.950e-02 |
0.0 |
COLLAGEN |
ECM-Receptor |
KEGG: hsa04512 |
| Fibroblasts(Nos)_source |
COL6A2_ligand |
Fibroblasts(Nos)_target |
CD44_receptor |
3.050e-02 |
0.0 |
COLLAGEN |
ECM-Receptor |
KEGG: hsa04512 |
| Fibroblasts(Nos)_source |
LAMB1_ligand |
Fibroblasts(Nos)_target |
CD44_receptor |
9.041e-03 |
0.0 |
LAMININ |
ECM-Receptor |
KEGG: hsa04512 |
| Fibroblasts(Nos)_source |
LAMB2_ligand |
Fibroblasts(Nos)_target |
CD44_receptor |
1.755e-03 |
0.03 |
LAMININ |
ECM-Receptor |
KEGG: hsa04512 |
| Fibroblasts(Nos)_source |
CLDN11_ligand |
Fibroblasts(Nos)_target |
CLDN11_receptor |
1.311e-02 |
0.0 |
CLDN |
Cell-Cell Contact |
KEGG: hsa04514 |