Sample overview
| Project Name |
TCGA-PRAD
|
| GSE ID |
GSE193337
|
| GSM ID |
GSM5793828
|
| Cell Line |
None
|
| Tissue type |
prostate
|
| Disease Type |
pT2c
|
| PMID |
35717322
|
| Initial gene number |
33538
|
| Initial cell number |
2574
|
| Post-QC gene number |
4256
|
| Post-QC cell number |
136
|
Bulk-to-ScRNA-seq Label Transfer
Bulk phenotype-associated subpopulations
Reference-Based Annotation
Differentially expressed genes
Overall Survival : Cluster
vs
There are no results of the analysis here
Overall Survival : Cluster
vs ( + )
There are no results of the analysis here
Clinical Stage : Cluster
vs
There
are no results of the analysis here
Tumor Size : Cluster
vs
There
are no results of the analysis here
Lymph Node Involvement : Cluster
vs
There
are no results of the analysis here
Distant Metastasis : Cluster
vs
There
are no results of the analysis here
Cell-Cell communications ( Survival-Associated Subpopulations Across Cell Types )
Cell Population Signaling and Communication
Ligand-Receptor-Mediated Cell-Cell Interactions
| Sending Cell Type |
Ligand |
Receiving Cell Type |
Receptor |
Score |
P-value |
Pathway Name |
Function |
Evidence |
| CD8+,T-cells(Nos)_source |
MIF_ligand |
CD8+,T-cells(Nos)_target |
CD74_CXCR4_receptor |
1.134e-02 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| CD8+,T-cells(Nos)_source |
MIF_ligand |
CD8+,T-cells(Nos)_target |
CD74_CD44_receptor |
7.621e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| CD8+,T-cells(Nos)_source |
TNF_ligand |
CD8+,T-cells(Nos)_target |
TNFRSF1A_receptor |
1.004e-03 |
0.0 |
TNF |
Secreted Signaling |
KEGG: hsa04060 |
| CD8+,T-cells(Nos)_source |
TNF_ligand |
CD8+,T-cells(Nos)_target |
TNFRSF1B_receptor |
2.375e-03 |
0.0 |
TNF |
Secreted Signaling |
KEGG: hsa04060 |
| CD8+,T-cells(Nos)_source |
ADGRE5_ligand |
CD8+,T-cells(Nos)_target |
CD55_receptor |
1.531e-03 |
0.0 |
ADGRE5 |
Cell-Cell Contact |
PMID: 11297558 |
| CD8+,T-cells(Nos)_source |
APP_ligand |
CD8+,T-cells(Nos)_target |
CD74_receptor |
1.612e-04 |
0.0 |
APP |
Cell-Cell Contact |
PMID: 19849849 |
| CD8+,T-cells(Nos)_source |
CD99_ligand |
CD8+,T-cells(Nos)_target |
CD99_receptor |
4.420e-02 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
CLEC2D_ligand |
CD8+,T-cells(Nos)_target |
KLRB1_receptor |
3.211e-02 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| CD8+,T-cells(Nos)_source |
CLEC2B_ligand |
CD8+,T-cells(Nos)_target |
KLRB1_receptor |
2.659e-02 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| CD8+,T-cells(Nos)_source |
CD69_ligand |
CD8+,T-cells(Nos)_target |
KLRB1_receptor |
7.914e-02 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| Adipocytes(Nos)_source |
ITGB2_ligand |
CD8+,T-cells(Nos)_target |
CD226_receptor |
8.648e-10 |
0.0 |
ITGB2 |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
ITGB2_ligand |
CD8+,T-cells(Nos)_target |
CD226_receptor |
8.653e-04 |
0.0 |
ITGB2 |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
LCK_ligand |
CD8+,T-cells(Nos)_target |
CD8 receptor_receptor |
5.854e-03 |
0.0 |
LCK |
Cell-Cell Contact |
PMID: 25427562 |
| CD8+,T-cells(Nos)_source |
HLA-A_ligand |
CD8+,T-cells(Nos)_target |
CD8A_receptor |
2.150e-02 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
HLA-B_ligand |
CD8+,T-cells(Nos)_target |
CD8A_receptor |
2.117e-02 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
HLA-C_ligand |
CD8+,T-cells(Nos)_target |
CD8A_receptor |
2.211e-02 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
HLA-E_ligand |
CD8+,T-cells(Nos)_target |
CD8A_receptor |
2.795e-02 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
HLA-F_ligand |
CD8+,T-cells(Nos)_target |
CD8A_receptor |
1.161e-02 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
HLA-A_ligand |
CD8+,T-cells(Nos)_target |
CD8B_receptor |
2.082e-02 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
HLA-B_ligand |
CD8+,T-cells(Nos)_target |
CD8B_receptor |
2.051e-02 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
HLA-C_ligand |
CD8+,T-cells(Nos)_target |
CD8B_receptor |
2.142e-02 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
HLA-E_ligand |
CD8+,T-cells(Nos)_target |
CD8B_receptor |
2.708e-02 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
HLA-F_ligand |
CD8+,T-cells(Nos)_target |
CD8B_receptor |
1.124e-02 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
HLA-E_ligand |
CD8+,T-cells(Nos)_target |
KLRC1_receptor |
5.266e-03 |
0.0 |
MHC-I |
Cell-Cell Contact |
PMID: 24223577 |
| CD8+,T-cells(Nos)_source |
HLA-E_ligand |
CD8+,T-cells(Nos)_target |
CD94:NKG2A_receptor |
7.304e-03 |
0.0 |
MHC-I |
Cell-Cell Contact |
PMID: 28484462 |