Sample overview
| Project Name |
TCGA-OV
|
| GSE ID |
GSE195486
|
| GSM ID |
GSM5798832
|
| Cell Line |
None
|
| Tissue type |
High Grade Serous Ovarian Cancer tumor tissue
|
| Disease Type |
High Grade Serous Ovarian Cancer tumor
|
| PMID |
35427494
|
| Initial gene number |
33562
|
| Initial cell number |
5201
|
| Post-QC gene number |
4794
|
| Post-QC cell number |
1573
|
Bulk-to-ScRNA-seq Label Transfer
Bulk phenotype-associated subpopulations
Reference-Based Annotation
Differentially expressed genes
Overall Survival : Cluster
vs
There are no results of the analysis here
Overall Survival : Cluster
vs ( + )
There are no results of the analysis here
Clinical Stage : Cluster
vs
There
are no results of the analysis here
Tumor Size : Cluster
vs
There
are no results of the analysis here
Lymph Node Involvement : Cluster
vs
There
are no results of the analysis here
Distant Metastasis : Cluster
vs
There
are no results of the analysis here
Cell-Cell communications ( Survival-Associated Subpopulations Across Cell Types )
Cell Population Signaling and Communication
Ligand-Receptor-Mediated Cell-Cell Interactions
| Sending Cell Type |
Ligand |
Receiving Cell Type |
Receptor |
Score |
P-value |
Pathway Name |
Function |
Evidence |
| CD8+,T-cells(Nos)_source |
CCL4_ligand |
CD8+,T-cells(Nos)_target |
CCR5_receptor |
1.605e-02 |
0.0 |
CCL |
Secreted Signaling |
KEGG: hsa04060 |
| CD8+,T-cells(Nos)_source |
CCL5_ligand |
CD8+,T-cells(Nos)_target |
CCR5_receptor |
4.228e-02 |
0.0 |
CCL |
Secreted Signaling |
KEGG: hsa04060 |
| CD8+,T-cells(Nos)_source |
MIF_ligand |
CD8+,T-cells(Nos)_target |
CD74_CXCR4_receptor |
3.390e-02 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| CD8+,T-cells(Nos)_source |
MIF_ligand |
CD8+,T-cells(Nos)_target |
CD74_CD44_receptor |
3.791e-02 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| CD8+,T-cells(Nos)_source |
TNF_ligand |
CD4+,T-cells(Nos)_target |
TNFRSF1A_receptor |
1.225e-05 |
0.0 |
TNF |
Secreted Signaling |
KEGG: hsa04060 |
| CD8+,T-cells(Nos)_source |
TNF_ligand |
CD8+,T-cells(Nos)_target |
TNFRSF1A_receptor |
1.750e-04 |
0.0 |
TNF |
Secreted Signaling |
KEGG: hsa04060 |
| CD8+,T-cells(Nos)_source |
TNF_ligand |
CD4+,T-cells(Nos)_target |
TNFRSF1B_receptor |
5.687e-06 |
0.0 |
TNF |
Secreted Signaling |
KEGG: hsa04060 |
| CD8+,T-cells(Nos)_source |
TNF_ligand |
CD8+,T-cells(Nos)_target |
TNFRSF1B_receptor |
1.554e-03 |
0.0 |
TNF |
Secreted Signaling |
KEGG: hsa04060 |
| CD8+,T-cells(Nos)_source |
FASLG_ligand |
CD8+,T-cells(Nos)_target |
FAS_receptor |
2.381e-05 |
0.0 |
FASLG |
Secreted Signaling |
KEGG: hsa04060 |
| CD8+,T-cells(Nos)_source |
TNFSF10_ligand |
CD8+,T-cells(Nos)_target |
TNFRSF10A_receptor |
1.693e-04 |
0.0 |
TRAIL |
Secreted Signaling |
KEGG: hsa04060 |
| CD8+,T-cells(Nos)_source |
GZMA_ligand |
CD8+,T-cells(Nos)_target |
F2R_receptor |
1.224e-02 |
0.0 |
PARs |
Secreted Signaling |
KEGG: hsa04080 |
| CD4+,T-cells(Nos)_source |
ADGRE5_ligand |
CD4+,T-cells(Nos)_target |
CD55_receptor |
3.750e-04 |
0.0 |
ADGRE5 |
Cell-Cell Contact |
PMID: 11297558 |
| CD8+,T-cells(Nos)_source |
ADGRE5_ligand |
CD4+,T-cells(Nos)_target |
CD55_receptor |
6.524e-03 |
0.0 |
ADGRE5 |
Cell-Cell Contact |
PMID: 11297558 |
| CD8+,T-cells(Nos)_source |
CD48_ligand |
CD8+,T-cells(Nos)_target |
CD244_receptor |
2.724e-05 |
0.0 |
CD48 |
Cell-Cell Contact |
PMID: 26697006 |
| CD8+,T-cells(Nos)_source |
CD99_ligand |
CD8+,T-cells(Nos)_target |
CD99_receptor |
1.379e-01 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
LCK_ligand |
CD8+,T-cells(Nos)_target |
CD8 receptor_receptor |
6.094e-02 |
0.0 |
LCK |
Cell-Cell Contact |
PMID: 25427562 |
| CD8+,T-cells(Nos)_source |
HLA-A_ligand |
CD8+,T-cells(Nos)_target |
CD8A_receptor |
1.201e-01 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
HLA-B_ligand |
CD8+,T-cells(Nos)_target |
CD8A_receptor |
1.341e-01 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
HLA-C_ligand |
CD8+,T-cells(Nos)_target |
CD8A_receptor |
1.326e-01 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD4+,T-cells(Nos)_source |
HLA-E_ligand |
CD8+,T-cells(Nos)_target |
CD8A_receptor |
2.286e-02 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
HLA-E_ligand |
CD8+,T-cells(Nos)_target |
CD8A_receptor |
1.652e-01 |
0.0 |
MHC-I |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD4+,T-cells(Nos)_source |
SELPLG_ligand |
CD4+,T-cells(Nos)_target |
SELL_receptor |
2.895e-04 |
0.0 |
SELPLG |
Cell-Cell Contact |
PMC2431087; PMID: 8892633,PMID: 8896607 |
| CD8+,T-cells(Nos)_source |
SELPLG_ligand |
CD4+,T-cells(Nos)_target |
SELL_receptor |
6.017e-03 |
0.0 |
SELPLG |
Cell-Cell Contact |
PMC2431087; PMID: 8892633,PMID: 8896607 |