Sample overview
| Project Name |
TCGA-LGG
|
| GSE ID |
GSE152273
|
| GSM ID |
GSM4610547
|
| Cell Line |
None
|
| Tissue type |
Brain
|
| Disease Type |
primary glioma
|
| PMID |
34586841
|
| Initial gene number |
32738
|
| Initial cell number |
269
|
| Post-QC gene number |
11438
|
| Post-QC cell number |
161
|
Bulk-to-ScRNA-seq Label Transfer
Bulk phenotype-associated subpopulations
Reference-Based Annotation
Differentially expressed genes
Overall Survival : Cluster
vs
There are no results of the analysis here
Overall Survival : Cluster
vs ( + )
There are no results of the analysis here
Clinical Stage : Cluster
vs
There
are no results of the analysis here
Tumor Size : Cluster
vs
There
are no results of the analysis here
Lymph Node Involvement : Cluster
vs
There
are no results of the analysis here
Distant Metastasis : Cluster
vs
There
are no results of the analysis here
Cell-Cell communications ( Survival-Associated Subpopulations Across Cell Types )
Cell Population Signaling and Communication
Ligand-Receptor-Mediated Cell-Cell Interactions
| Sending Cell Type |
Ligand |
Receiving Cell Type |
Receptor |
Score |
P-value |
Pathway Name |
Function |
Evidence |
| Macrophages(Good)_source |
MIF_ligand |
Macrophages(Good)_target |
CD74_CD44_receptor |
1.062e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Macrophages(Good)_source |
MIF_ligand |
Macrophages(Nos)_target |
CD74_CD44_receptor |
7.212e-05 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Macrophages(Good)_source |
MIF_ligand |
Macrophages(Poor)_target |
CD74_CD44_receptor |
1.281e-04 |
0.01 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Macrophages(Nos)_source |
SPP1_ligand |
Macrophages(Good)_target |
CD44_receptor |
2.693e-05 |
0.0 |
SPP1 |
Secreted Signaling |
PMID: 21907263 |
| Macrophages(Poor)_source |
SPP1_ligand |
Macrophages(Good)_target |
CD44_receptor |
6.923e-05 |
0.0 |
SPP1 |
Secreted Signaling |
PMID: 21907263 |
| Macrophages(Nos)_source |
SPP1_ligand |
Macrophages(Nos)_target |
CD44_receptor |
1.607e-05 |
0.01 |
SPP1 |
Secreted Signaling |
PMID: 21907263 |
| Macrophages(Poor)_source |
SPP1_ligand |
Macrophages(Nos)_target |
CD44_receptor |
4.130e-05 |
0.0 |
SPP1 |
Secreted Signaling |
PMID: 21907263 |
| Macrophages(Good)_source |
ANXA1_ligand |
Macrophages(Nos)_target |
FPR1_receptor |
3.793e-06 |
0.0 |
ANNEXIN |
Secreted Signaling |
PMID: 23230437 |
| Macrophages(Nos)_source |
ANXA1_ligand |
Macrophages(Nos)_target |
FPR1_receptor |
2.167e-06 |
0.0 |
ANNEXIN |
Secreted Signaling |
PMID: 23230437 |
| Macrophages(Poor)_source |
ANXA1_ligand |
Macrophages(Nos)_target |
FPR1_receptor |
4.202e-06 |
0.02 |
ANNEXIN |
Secreted Signaling |
PMID: 23230437 |
| Macrophages(Nos)_source |
GRN_ligand |
Macrophages(Nos)_target |
SORT1_receptor |
7.863e-04 |
0.0 |
GRN |
Secreted Signaling |
PMID: 29555433 |
| Macrophages(Nos)_source |
GRN_ligand |
Macrophages(Poor)_target |
SORT1_receptor |
8.110e-04 |
0.04 |
GRN |
Secreted Signaling |
PMID: 29555433 |
| Macrophages(Nos)_source |
CD99_ligand |
Macrophages(Good)_target |
CD99_receptor |
4.074e-03 |
0.01 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Macrophages(Good)_source |
CD99_ligand |
Macrophages(Nos)_target |
CD99_receptor |
4.074e-03 |
0.01 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Macrophages(Nos)_source |
CD99_ligand |
Macrophages(Nos)_target |
CD99_receptor |
3.414e-03 |
0.02 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Macrophages(Nos)_source |
CNTN2_ligand |
Macrophages(Good)_target |
CNTN2_receptor |
7.022e-09 |
0.0 |
CNTN |
Cell-Cell Contact |
KEGG: hsa04514 |
| Macrophages(Good)_source |
CNTN2_ligand |
Macrophages(Nos)_target |
CNTN2_receptor |
7.022e-09 |
0.0 |
CNTN |
Cell-Cell Contact |
KEGG: hsa04514 |
| Macrophages(Nos)_source |
CNTN2_ligand |
Macrophages(Nos)_target |
CNTN2_receptor |
4.143e-09 |
0.04 |
CNTN |
Cell-Cell Contact |
KEGG: hsa04514 |
| Macrophages(Nos)_source |
HLA-DMB_ligand |
Macrophages(Good)_target |
CD4_receptor |
2.574e-04 |
0.02 |
MHC-II |
Cell-Cell Contact |
KEGG: hsa04514 |
| Macrophages(Nos)_source |
HLA-DMB_ligand |
Macrophages(Nos)_target |
CD4_receptor |
3.014e-04 |
0.01 |
MHC-II |
Cell-Cell Contact |
KEGG: hsa04514 |
| Macrophages(Nos)_source |
HLA-DMB_ligand |
Macrophages(Poor)_target |
CD4_receptor |
3.246e-04 |
0.04 |
MHC-II |
Cell-Cell Contact |
KEGG: hsa04514 |
| Macrophages(Good)_source |
HLA-DQB1_ligand |
Macrophages(Good)_target |
CD4_receptor |
8.073e-05 |
0.01 |
MHC-II |
Cell-Cell Contact |
KEGG: hsa04514 |
| Macrophages(Good)_source |
HLA-DQB1_ligand |
Macrophages(Nos)_target |
CD4_receptor |
9.493e-05 |
0.0 |
MHC-II |
Cell-Cell Contact |
KEGG: hsa04514 |
| Macrophages(Good)_source |
HLA-DQB1_ligand |
Macrophages(Poor)_target |
CD4_receptor |
1.018e-04 |
0.0 |
MHC-II |
Cell-Cell Contact |
KEGG: hsa04514 |