Sample overview
| Project Name |
TCGA-LGG
|
| GSE ID |
GSE152273
|
| GSM ID |
GSM4610545
|
| Cell Line |
None
|
| Tissue type |
Brain
|
| Disease Type |
primary glioma
|
| PMID |
34586841
|
| Initial gene number |
32738
|
| Initial cell number |
1659
|
| Post-QC gene number |
1175
|
| Post-QC cell number |
208
|
Bulk-to-ScRNA-seq Label Transfer
Bulk phenotype-associated subpopulations
Reference-Based Annotation
Differentially expressed genes
Overall Survival : Cluster
vs
There are no results of the analysis here
Overall Survival : Cluster
vs ( + )
There are no results of the analysis here
Clinical Stage : Cluster
vs
There
are no results of the analysis here
Tumor Size : Cluster
vs
There
are no results of the analysis here
Lymph Node Involvement : Cluster
vs
There
are no results of the analysis here
Distant Metastasis : Cluster
vs
There
are no results of the analysis here
Cell-Cell communications ( Survival-Associated Subpopulations Across Cell Types )
Cell Population Signaling and Communication
Ligand-Receptor-Mediated Cell-Cell Interactions
| Sending Cell Type |
Ligand |
Receiving Cell Type |
Receptor |
Score |
P-value |
Pathway Name |
Function |
Evidence |
| Neurons(Good)_source |
PTN_ligand |
Erythrocytes(Good)_target |
NCL_receptor |
2.659e-04 |
0.01 |
PTN |
Secreted Signaling |
PMID: 28356350; PMID: 25620911 |
| Neurons(Poor)_source |
PTN_ligand |
Erythrocytes(Good)_target |
NCL_receptor |
1.279e-04 |
0.03 |
PTN |
Secreted Signaling |
PMID: 28356350; PMID: 25620911 |
| Neurons(Good)_source |
PTN_ligand |
Erythrocytes(Poor)_target |
NCL_receptor |
6.132e-04 |
0.0 |
PTN |
Secreted Signaling |
PMID: 28356350; PMID: 25620911 |
| Neurons(Poor)_source |
PTN_ligand |
Erythrocytes(Poor)_target |
NCL_receptor |
2.948e-04 |
0.0 |
PTN |
Secreted Signaling |
PMID: 28356350; PMID: 25620911 |
| Neurons(Good)_source |
PTN_ligand |
Neurons(Good)_target |
NCL_receptor |
3.481e-03 |
0.0 |
PTN |
Secreted Signaling |
PMID: 28356350; PMID: 25620911 |
| Neurons(Poor)_source |
PTN_ligand |
Neurons(Good)_target |
NCL_receptor |
1.673e-03 |
0.0 |
PTN |
Secreted Signaling |
PMID: 28356350; PMID: 25620911 |
| Neurons(Good)_source |
PTN_ligand |
Neurons(Poor)_target |
NCL_receptor |
1.829e-03 |
0.0 |
PTN |
Secreted Signaling |
PMID: 28356350; PMID: 25620911 |
| Neurons(Poor)_source |
PTN_ligand |
Neurons(Poor)_target |
NCL_receptor |
8.788e-04 |
0.0 |
PTN |
Secreted Signaling |
PMID: 28356350; PMID: 25620911 |
| Macrophages(Poor)_source |
GRN_ligand |
Neurons(Good)_target |
SORT1_receptor |
1.124e-03 |
0.0 |
GRN |
Secreted Signaling |
PMID: 29555433 |
| Neurons(Good)_source |
GRN_ligand |
Neurons(Good)_target |
SORT1_receptor |
6.485e-04 |
0.0 |
GRN |
Secreted Signaling |
PMID: 29555433 |
| Neurons(Poor)_source |
GRN_ligand |
Neurons(Good)_target |
SORT1_receptor |
7.089e-04 |
0.0 |
GRN |
Secreted Signaling |
PMID: 29555433 |
| Macrophages(Poor)_source |
GRN_ligand |
Neurons(Poor)_target |
SORT1_receptor |
5.323e-04 |
0.0 |
GRN |
Secreted Signaling |
PMID: 29555433 |
| Neurons(Good)_source |
GRN_ligand |
Neurons(Poor)_target |
SORT1_receptor |
3.069e-04 |
0.0 |
GRN |
Secreted Signaling |
PMID: 29555433 |
| Neurons(Poor)_source |
GRN_ligand |
Neurons(Poor)_target |
SORT1_receptor |
3.355e-04 |
0.0 |
GRN |
Secreted Signaling |
PMID: 29555433 |
| Macrophages(Poor)_source |
GRN_ligand |
Neutrophils(Poor)_target |
SORT1_receptor |
1.775e-04 |
0.0 |
GRN |
Secreted Signaling |
PMID: 29555433 |
| Neurons(Good)_source |
GRN_ligand |
Neutrophils(Poor)_target |
SORT1_receptor |
9.909e-05 |
0.01 |
GRN |
Secreted Signaling |
PMID: 29555433 |
| Macrophages(Poor)_source |
PSAP_ligand |
Neurons(Good)_target |
GPR37_receptor |
2.853e-03 |
0.0 |
PSAP |
Secreted Signaling |
PMID: 23690594 |
| Neurons(Good)_source |
PSAP_ligand |
Neurons(Good)_target |
GPR37_receptor |
5.808e-03 |
0.0 |
PSAP |
Secreted Signaling |
PMID: 23690594 |
| Neurons(Poor)_source |
PSAP_ligand |
Neurons(Good)_target |
GPR37_receptor |
2.777e-03 |
0.0 |
PSAP |
Secreted Signaling |
PMID: 23690594 |
| Neutrophils(Poor)_source |
PSAP_ligand |
Neurons(Good)_target |
GPR37_receptor |
2.607e-03 |
0.0 |
PSAP |
Secreted Signaling |
PMID: 23690594 |
| Macrophages(Poor)_source |
PSAP_ligand |
Neurons(Poor)_target |
GPR37_receptor |
1.217e-03 |
0.0 |
PSAP |
Secreted Signaling |
PMID: 23690594 |
| Neurons(Good)_source |
PSAP_ligand |
Neurons(Poor)_target |
GPR37_receptor |
2.474e-03 |
0.0 |
PSAP |
Secreted Signaling |
PMID: 23690594 |
| Neurons(Poor)_source |
PSAP_ligand |
Neurons(Poor)_target |
GPR37_receptor |
1.183e-03 |
0.0 |
PSAP |
Secreted Signaling |
PMID: 23690594 |
| Neutrophils(Poor)_source |
PSAP_ligand |
Neurons(Poor)_target |
GPR37_receptor |
1.108e-03 |
0.0 |
PSAP |
Secreted Signaling |
PMID: 23690594 |
| Macrophages(Poor)_source |
PSAP_ligand |
Neutrophils(Poor)_target |
GPR37_receptor |
5.114e-04 |
0.04 |
PSAP |
Secreted Signaling |
PMID: 23690594 |
| Neurons(Good)_source |
PSAP_ligand |
Neutrophils(Poor)_target |
GPR37_receptor |
1.031e-03 |
0.0 |
PSAP |
Secreted Signaling |
PMID: 23690594 |
| Neurons(Poor)_source |
PSAP_ligand |
Neutrophils(Poor)_target |
GPR37_receptor |
4.933e-04 |
0.03 |
PSAP |
Secreted Signaling |
PMID: 23690594 |
| Neurons(Good)_source |
CLDN11_ligand |
Neurons(Good)_target |
CLDN11_receptor |
1.687e-02 |
0.0 |
CLDN |
Cell-Cell Contact |
KEGG: hsa04514 |
| Neurons(Poor)_source |
CLDN11_ligand |
Neurons(Good)_target |
CLDN11_receptor |
7.916e-03 |
0.0 |
CLDN |
Cell-Cell Contact |
KEGG: hsa04514 |
| Neutrophils(Poor)_source |
CLDN11_ligand |
Neurons(Good)_target |
CLDN11_receptor |
6.962e-03 |
0.0 |
CLDN |
Cell-Cell Contact |
KEGG: hsa04514 |
| Neurons(Good)_source |
CLDN11_ligand |
Neurons(Poor)_target |
CLDN11_receptor |
7.916e-03 |
0.0 |
CLDN |
Cell-Cell Contact |
KEGG: hsa04514 |
| Neurons(Poor)_source |
CLDN11_ligand |
Neurons(Poor)_target |
CLDN11_receptor |
3.715e-03 |
0.01 |
CLDN |
Cell-Cell Contact |
KEGG: hsa04514 |
| Neutrophils(Poor)_source |
CLDN11_ligand |
Neurons(Poor)_target |
CLDN11_receptor |
3.261e-03 |
0.0 |
CLDN |
Cell-Cell Contact |
KEGG: hsa04514 |
| Neurons(Good)_source |
CLDN11_ligand |
Neutrophils(Poor)_target |
CLDN11_receptor |
6.962e-03 |
0.0 |
CLDN |
Cell-Cell Contact |
KEGG: hsa04514 |
| Neurons(Poor)_source |
CLDN11_ligand |
Neutrophils(Poor)_target |
CLDN11_receptor |
3.261e-03 |
0.0 |
CLDN |
Cell-Cell Contact |
KEGG: hsa04514 |
| Neurons(Good)_source |
CNTN2_ligand |
Neurons(Good)_target |
CNTN2_receptor |
3.413e-03 |
0.0 |
CNTN |
Cell-Cell Contact |
KEGG: hsa04514 |
| Neurons(Poor)_source |
CNTN2_ligand |
Neurons(Good)_target |
CNTN2_receptor |
1.621e-03 |
0.0 |
CNTN |
Cell-Cell Contact |
KEGG: hsa04514 |
| Neutrophils(Poor)_source |
CNTN2_ligand |
Neurons(Good)_target |
CNTN2_receptor |
6.302e-04 |
0.0 |
CNTN |
Cell-Cell Contact |
KEGG: hsa04514 |
| Neurons(Good)_source |
CNTN2_ligand |
Neurons(Poor)_target |
CNTN2_receptor |
1.621e-03 |
0.0 |
CNTN |
Cell-Cell Contact |
KEGG: hsa04514 |
| Neurons(Poor)_source |
CNTN2_ligand |
Neurons(Poor)_target |
CNTN2_receptor |
7.696e-04 |
0.0 |
CNTN |
Cell-Cell Contact |
KEGG: hsa04514 |
| Neutrophils(Poor)_source |
CNTN2_ligand |
Neurons(Poor)_target |
CNTN2_receptor |
2.992e-04 |
0.02 |
CNTN |
Cell-Cell Contact |
KEGG: hsa04514 |
| Neurons(Good)_source |
CNTN2_ligand |
Neutrophils(Poor)_target |
CNTN2_receptor |
6.302e-04 |
0.0 |
CNTN |
Cell-Cell Contact |
KEGG: hsa04514 |
| Neurons(Poor)_source |
CNTN2_ligand |
Neutrophils(Poor)_target |
CNTN2_receptor |
2.992e-04 |
0.02 |
CNTN |
Cell-Cell Contact |
KEGG: hsa04514 |
| Neurons(Good)_source |
JAM3_ligand |
Neurons(Good)_target |
JAM3_receptor |
6.044e-03 |
0.0 |
JAM |
Cell-Cell Contact |
KEGG: hsa04514 |
| Neurons(Poor)_source |
JAM3_ligand |
Neurons(Good)_target |
JAM3_receptor |
2.862e-03 |
0.0 |
JAM |
Cell-Cell Contact |
KEGG: hsa04514 |
| Neurons(Good)_source |
JAM3_ligand |
Neurons(Poor)_target |
JAM3_receptor |
2.862e-03 |
0.0 |
JAM |
Cell-Cell Contact |
KEGG: hsa04514 |
| Neurons(Poor)_source |
JAM3_ligand |
Neurons(Poor)_target |
JAM3_receptor |
1.355e-03 |
0.0 |
JAM |
Cell-Cell Contact |
KEGG: hsa04514 |
| Neurons(Good)_source |
MAG_ligand |
Neurons(Good)_target |
MAG_receptor |
1.731e-02 |
0.0 |
MAG |
Cell-Cell Contact |
KEGG: hsa04514 |
| Neurons(Poor)_source |
MAG_ligand |
Neurons(Good)_target |
MAG_receptor |
8.191e-03 |
0.0 |
MAG |
Cell-Cell Contact |
KEGG: hsa04514 |
| Neutrophils(Poor)_source |
MAG_ligand |
Neurons(Good)_target |
MAG_receptor |
8.599e-03 |
0.0 |
MAG |
Cell-Cell Contact |
KEGG: hsa04514 |
| Neurons(Good)_source |
MAG_ligand |
Neurons(Poor)_target |
MAG_receptor |
8.191e-03 |
0.0 |
MAG |
Cell-Cell Contact |
KEGG: hsa04514 |
| Neurons(Poor)_source |
MAG_ligand |
Neurons(Poor)_target |
MAG_receptor |
3.876e-03 |
0.0 |
MAG |
Cell-Cell Contact |
KEGG: hsa04514 |
| Neutrophils(Poor)_source |
MAG_ligand |
Neurons(Poor)_target |
MAG_receptor |
4.069e-03 |
0.0 |
MAG |
Cell-Cell Contact |
KEGG: hsa04514 |
| Neurons(Good)_source |
MAG_ligand |
Neutrophils(Poor)_target |
MAG_receptor |
8.599e-03 |
0.0 |
MAG |
Cell-Cell Contact |
KEGG: hsa04514 |
| Neurons(Poor)_source |
MAG_ligand |
Neutrophils(Poor)_target |
MAG_receptor |
4.069e-03 |
0.0 |
MAG |
Cell-Cell Contact |
KEGG: hsa04514 |
| Neutrophils(Poor)_source |
MAG_ligand |
Neutrophils(Poor)_target |
MAG_receptor |
4.271e-03 |
0.0 |
MAG |
Cell-Cell Contact |
KEGG: hsa04514 |
| Neurons(Good)_source |
NCAM1_ligand |
Neurons(Good)_target |
NCAM1_receptor |
1.014e-02 |
0.0 |
NCAM |
Cell-Cell Contact |
KEGG: hsa04514 |
| Neurons(Poor)_source |
NCAM1_ligand |
Neurons(Good)_target |
NCAM1_receptor |
4.786e-03 |
0.0 |
NCAM |
Cell-Cell Contact |
KEGG: hsa04514 |
| Neutrophils(Poor)_source |
NCAM1_ligand |
Neurons(Good)_target |
NCAM1_receptor |
1.954e-03 |
0.0 |
NCAM |
Cell-Cell Contact |
KEGG: hsa04514 |
| Neurons(Good)_source |
NCAM1_ligand |
Neurons(Poor)_target |
NCAM1_receptor |
4.786e-03 |
0.0 |
NCAM |
Cell-Cell Contact |
KEGG: hsa04514 |
| Neurons(Poor)_source |
NCAM1_ligand |
Neurons(Poor)_target |
NCAM1_receptor |
2.259e-03 |
0.0 |
NCAM |
Cell-Cell Contact |
KEGG: hsa04514 |
| Neutrophils(Poor)_source |
NCAM1_ligand |
Neurons(Poor)_target |
NCAM1_receptor |
9.203e-04 |
0.01 |
NCAM |
Cell-Cell Contact |
KEGG: hsa04514 |
| Neurons(Good)_source |
NCAM1_ligand |
Neutrophils(Poor)_target |
NCAM1_receptor |
1.954e-03 |
0.0 |
NCAM |
Cell-Cell Contact |
KEGG: hsa04514 |
| Neurons(Poor)_source |
NCAM1_ligand |
Neutrophils(Poor)_target |
NCAM1_receptor |
9.203e-04 |
0.01 |
NCAM |
Cell-Cell Contact |
KEGG: hsa04514 |