Sample overview
| Project Name |
TCGA-LAML
|
| GSE ID |
GSE235923
|
| GSM ID |
GSM7512022
|
| Cell Line |
None
|
| Tissue type |
Bone Marrow
|
| Disease Type |
Acute megakaryoblastic leukemia
|
| PMID |
37798266
|
| Initial gene number |
36613
|
| Initial cell number |
2352
|
| Post-QC gene number |
2294
|
| Post-QC cell number |
1558
|
Bulk-to-ScRNA-seq Label Transfer
Bulk phenotype-associated subpopulations
Reference-Based Annotation
Differentially expressed genes
Overall Survival : Cluster
vs
There are no results of the analysis here
Overall Survival : Cluster
vs ( + )
There are no results of the analysis here
Clinical Stage : Cluster
vs
There
are no results of the analysis here
Tumor Size : Cluster
vs
There
are no results of the analysis here
Lymph Node Involvement : Cluster
vs
There
are no results of the analysis here
Distant Metastasis : Cluster
vs
There
are no results of the analysis here
Cell-Cell communications ( Survival-Associated Subpopulations Across Cell Types )
Cell Population Signaling and Communication
Ligand-Receptor-Mediated Cell-Cell Interactions
| Sending Cell Type |
Ligand |
Receiving Cell Type |
Receptor |
Score |
P-value |
Pathway Name |
Function |
Evidence |
| B-cells(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CXCR4_receptor |
2.643e-05 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| CD4+,T-cells(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CXCR4_receptor |
1.026e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| Erythrocytes(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CXCR4_receptor |
6.774e-05 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| HSC(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CXCR4_receptor |
1.253e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| Monocytes(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CXCR4_receptor |
1.018e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| B-cells(Nos)_source |
MIF_ligand |
HSC(Nos)_target |
CD74_CXCR4_receptor |
4.811e-05 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| CD4+,T-cells(Nos)_source |
MIF_ligand |
HSC(Nos)_target |
CD74_CXCR4_receptor |
1.869e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| Erythrocytes(Nos)_source |
MIF_ligand |
HSC(Nos)_target |
CD74_CXCR4_receptor |
1.227e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| HSC(Nos)_source |
MIF_ligand |
HSC(Nos)_target |
CD74_CXCR4_receptor |
2.285e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| Monocytes(Nos)_source |
MIF_ligand |
HSC(Nos)_target |
CD74_CXCR4_receptor |
1.855e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| B-cells(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CXCR4_receptor |
1.679e-05 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| CD4+,T-cells(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CXCR4_receptor |
6.527e-05 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| HSC(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CXCR4_receptor |
7.989e-05 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| Monocytes(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CXCR4_receptor |
6.481e-05 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| B-cells(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CD44_receptor |
9.584e-06 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| CD4+,T-cells(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CD44_receptor |
3.724e-05 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| HSC(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CD44_receptor |
4.556e-05 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Monocytes(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CD44_receptor |
3.697e-05 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| B-cells(Nos)_source |
MIF_ligand |
HSC(Nos)_target |
CD74_CD44_receptor |
9.600e-05 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| CD4+,T-cells(Nos)_source |
MIF_ligand |
HSC(Nos)_target |
CD74_CD44_receptor |
3.727e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Erythrocytes(Nos)_source |
MIF_ligand |
HSC(Nos)_target |
CD74_CD44_receptor |
2.462e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| HSC(Nos)_source |
MIF_ligand |
HSC(Nos)_target |
CD74_CD44_receptor |
4.548e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Monocytes(Nos)_source |
MIF_ligand |
HSC(Nos)_target |
CD74_CD44_receptor |
3.697e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| B-cells(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
5.204e-05 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| CD4+,T-cells(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
2.022e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Erythrocytes(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
1.328e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| HSC(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
2.471e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Monocytes(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
2.006e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| B-cells(Nos)_source |
THBS1_ligand |
Erythrocytes(Nos)_target |
CD36_receptor |
1.174e-08 |
0.0 |
THBS |
ECM-Receptor |
KEGG: hsa04512 |
| CD4+,T-cells(Nos)_source |
THBS1_ligand |
Erythrocytes(Nos)_target |
CD36_receptor |
1.413e-07 |
0.0 |
THBS |
ECM-Receptor |
KEGG: hsa04512 |
| Erythrocytes(Nos)_source |
THBS1_ligand |
Erythrocytes(Nos)_target |
CD36_receptor |
1.308e-08 |
0.0 |
THBS |
ECM-Receptor |
KEGG: hsa04512 |
| HSC(Nos)_source |
THBS1_ligand |
Erythrocytes(Nos)_target |
CD36_receptor |
1.728e-07 |
0.0 |
THBS |
ECM-Receptor |
KEGG: hsa04512 |
| Monocytes(Nos)_source |
THBS1_ligand |
Erythrocytes(Nos)_target |
CD36_receptor |
8.872e-04 |
0.0 |
THBS |
ECM-Receptor |
KEGG: hsa04512 |
| CD4+,T-cells(Nos)_source |
THBS1_ligand |
B-cells(Nos)_target |
CD47_receptor |
3.450e-08 |
0.0 |
THBS |
ECM-Receptor |
KEGG: hsa04512 |
| HSC(Nos)_source |
THBS1_ligand |
B-cells(Nos)_target |
CD47_receptor |
4.218e-08 |
0.01 |
THBS |
ECM-Receptor |
KEGG: hsa04512 |
| Monocytes(Nos)_source |
THBS1_ligand |
B-cells(Nos)_target |
CD47_receptor |
2.122e-04 |
0.0 |
THBS |
ECM-Receptor |
KEGG: hsa04512 |
| CD4+,T-cells(Nos)_source |
THBS1_ligand |
CD4+,T-cells(Nos)_target |
CD47_receptor |
2.665e-08 |
0.01 |
THBS |
ECM-Receptor |
KEGG: hsa04512 |
| HSC(Nos)_source |
THBS1_ligand |
CD4+,T-cells(Nos)_target |
CD47_receptor |
3.258e-08 |
0.01 |
THBS |
ECM-Receptor |
KEGG: hsa04512 |
| Monocytes(Nos)_source |
THBS1_ligand |
CD4+,T-cells(Nos)_target |
CD47_receptor |
1.681e-04 |
0.0 |
THBS |
ECM-Receptor |
KEGG: hsa04512 |
| Monocytes(Nos)_source |
THBS1_ligand |
Erythrocytes(Nos)_target |
CD47_receptor |
1.602e-05 |
0.01 |
THBS |
ECM-Receptor |
KEGG: hsa04512 |
| CD4+,T-cells(Nos)_source |
THBS1_ligand |
HSC(Nos)_target |
CD47_receptor |
9.594e-08 |
0.0 |
THBS |
ECM-Receptor |
KEGG: hsa04512 |
| HSC(Nos)_source |
THBS1_ligand |
HSC(Nos)_target |
CD47_receptor |
1.173e-07 |
0.01 |
THBS |
ECM-Receptor |
KEGG: hsa04512 |
| Monocytes(Nos)_source |
THBS1_ligand |
HSC(Nos)_target |
CD47_receptor |
5.937e-04 |
0.0 |
THBS |
ECM-Receptor |
KEGG: hsa04512 |
| Monocytes(Nos)_source |
THBS1_ligand |
Monocytes(Nos)_target |
CD47_receptor |
3.637e-05 |
0.0 |
THBS |
ECM-Receptor |
KEGG: hsa04512 |
| B-cells(Nos)_source |
CD99_ligand |
B-cells(Nos)_target |
CD99_receptor |
1.183e-04 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
CD99_ligand |
B-cells(Nos)_target |
CD99_receptor |
4.294e-04 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
CD99_ligand |
B-cells(Nos)_target |
CD99_receptor |
7.779e-05 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Nos)_source |
CD99_ligand |
HSC(Nos)_target |
CD99_receptor |
4.294e-04 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
CD99_ligand |
HSC(Nos)_target |
CD99_receptor |
1.559e-03 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
CD99_ligand |
HSC(Nos)_target |
CD99_receptor |
2.832e-04 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Nos)_source |
CD99_ligand |
Monocytes(Nos)_target |
CD99_receptor |
7.779e-05 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
CD99_ligand |
Monocytes(Nos)_target |
CD99_receptor |
2.832e-04 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |