Sample overview
| Project Name |
TCGA-LAML
|
| GSE ID |
GSE235923
|
| GSM ID |
GSM7512010
|
| Cell Line |
None
|
| Tissue type |
Bone Marrow
|
| Disease Type |
AML with mutated CEBPA
|
| PMID |
37798266
|
| Initial gene number |
33538
|
| Initial cell number |
3057
|
| Post-QC gene number |
1581
|
| Post-QC cell number |
1156
|
Bulk-to-ScRNA-seq Label Transfer
Bulk phenotype-associated subpopulations
Reference-Based Annotation
Differentially expressed genes
Overall Survival : Cluster
vs
There are no results of the analysis here
Overall Survival : Cluster
vs ( + )
There are no results of the analysis here
Clinical Stage : Cluster
vs
There
are no results of the analysis here
Tumor Size : Cluster
vs
There
are no results of the analysis here
Lymph Node Involvement : Cluster
vs
There
are no results of the analysis here
Distant Metastasis : Cluster
vs
There
are no results of the analysis here
Cell-Cell communications ( Survival-Associated Subpopulations Across Cell Types )
Cell Population Signaling and Communication
Ligand-Receptor-Mediated Cell-Cell Interactions
| Sending Cell Type |
Ligand |
Receiving Cell Type |
Receptor |
Score |
P-value |
Pathway Name |
Function |
Evidence |
| Erythrocytes(Good)_source |
MIF_ligand |
HSC(Good)_target |
CD74_CD44_receptor |
2.969e-09 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Erythrocytes(Nos)_source |
MIF_ligand |
HSC(Good)_target |
CD74_CD44_receptor |
2.387e-08 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Erythrocytes(Poor)_source |
MIF_ligand |
HSC(Good)_target |
CD74_CD44_receptor |
1.299e-09 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| HSC(Good)_source |
MIF_ligand |
HSC(Good)_target |
CD74_CD44_receptor |
2.912e-05 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| HSC(Nos)_source |
MIF_ligand |
HSC(Good)_target |
CD74_CD44_receptor |
3.251e-05 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| HSC(Poor)_source |
MIF_ligand |
HSC(Good)_target |
CD74_CD44_receptor |
9.002e-05 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Erythrocytes(Good)_source |
MIF_ligand |
HSC(Nos)_target |
CD74_CD44_receptor |
7.261e-09 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Erythrocytes(Nos)_source |
MIF_ligand |
HSC(Nos)_target |
CD74_CD44_receptor |
5.837e-08 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Erythrocytes(Poor)_source |
MIF_ligand |
HSC(Nos)_target |
CD74_CD44_receptor |
3.176e-09 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| HSC(Good)_source |
MIF_ligand |
HSC(Nos)_target |
CD74_CD44_receptor |
6.745e-05 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| HSC(Nos)_source |
MIF_ligand |
HSC(Nos)_target |
CD74_CD44_receptor |
7.610e-05 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| HSC(Poor)_source |
MIF_ligand |
HSC(Nos)_target |
CD74_CD44_receptor |
2.090e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Erythrocytes(Good)_source |
MIF_ligand |
HSC(Poor)_target |
CD74_CD44_receptor |
1.136e-08 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Erythrocytes(Nos)_source |
MIF_ligand |
HSC(Poor)_target |
CD74_CD44_receptor |
9.134e-08 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Erythrocytes(Poor)_source |
MIF_ligand |
HSC(Poor)_target |
CD74_CD44_receptor |
4.970e-09 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| HSC(Good)_source |
MIF_ligand |
HSC(Poor)_target |
CD74_CD44_receptor |
1.099e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| HSC(Nos)_source |
MIF_ligand |
HSC(Poor)_target |
CD74_CD44_receptor |
1.230e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| HSC(Poor)_source |
MIF_ligand |
HSC(Poor)_target |
CD74_CD44_receptor |
3.400e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| HSC(Poor)_source |
LGALS9_ligand |
HSC(Poor)_target |
PTPRC_receptor |
2.917e-05 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| HSC(Poor)_source |
LGALS9_ligand |
Erythrocytes(Good)_target |
CD44_receptor |
2.016e-09 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| HSC(Poor)_source |
LGALS9_ligand |
Erythrocytes(Nos)_target |
CD44_receptor |
1.581e-08 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| HSC(Poor)_source |
LGALS9_ligand |
Erythrocytes(Poor)_target |
CD44_receptor |
8.515e-10 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| HSC(Poor)_source |
LGALS9_ligand |
HSC(Good)_target |
CD44_receptor |
1.186e-05 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| HSC(Poor)_source |
LGALS9_ligand |
HSC(Nos)_target |
CD44_receptor |
5.347e-05 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| HSC(Poor)_source |
LGALS9_ligand |
HSC(Poor)_target |
CD44_receptor |
5.843e-05 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| HSC(Good)_source |
CD99_ligand |
HSC(Good)_target |
CD99_receptor |
9.355e-05 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
CD99_ligand |
HSC(Good)_target |
CD99_receptor |
1.299e-04 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Poor)_source |
CD99_ligand |
HSC(Good)_target |
CD99_receptor |
2.583e-04 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Good)_source |
CD99_ligand |
HSC(Nos)_target |
CD99_receptor |
1.299e-04 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
CD99_ligand |
HSC(Nos)_target |
CD99_receptor |
1.803e-04 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Poor)_source |
CD99_ligand |
HSC(Nos)_target |
CD99_receptor |
3.586e-04 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Good)_source |
CD99_ligand |
HSC(Poor)_target |
CD99_receptor |
2.583e-04 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
CD99_ligand |
HSC(Poor)_target |
CD99_receptor |
3.586e-04 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Poor)_source |
CD99_ligand |
HSC(Poor)_target |
CD99_receptor |
7.086e-04 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |