Sample overview
| Project Name |
TCGA-LAML
|
| GSE ID |
GSE235923
|
| GSM ID |
GSM7511998
|
| Cell Line |
None
|
| Tissue type |
Bone Marrow
|
| Disease Type |
AML with myelodysplasia-related changes
|
| PMID |
37798266
|
| Initial gene number |
33538
|
| Initial cell number |
4265
|
| Post-QC gene number |
3858
|
| Post-QC cell number |
2980
|
Bulk-to-ScRNA-seq Label Transfer
Bulk phenotype-associated subpopulations
Reference-Based Annotation
Differentially expressed genes
Overall Survival : Cluster
vs
There are no results of the analysis here
Overall Survival : Cluster
vs ( + )
There are no results of the analysis here
Clinical Stage : Cluster
vs
There
are no results of the analysis here
Tumor Size : Cluster
vs
There
are no results of the analysis here
Lymph Node Involvement : Cluster
vs
There
are no results of the analysis here
Distant Metastasis : Cluster
vs
There
are no results of the analysis here
Cell-Cell communications ( Survival-Associated Subpopulations Across Cell Types )
Cell Population Signaling and Communication
Ligand-Receptor-Mediated Cell-Cell Interactions
| Sending Cell Type |
Ligand |
Receiving Cell Type |
Receptor |
Score |
P-value |
Pathway Name |
Function |
Evidence |
| HSC(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CXCR4_receptor |
3.145e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| HSC(Nos)_source |
MIF_ligand |
HSC(Nos)_target |
CD74_CD44_receptor |
2.997e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Monocytes(Nos)_source |
MIF_ligand |
HSC(Nos)_target |
CD74_CD44_receptor |
4.337e-03 |
0.04 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| HSC(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
3.050e-03 |
0.01 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| HSC(Nos)_source |
LGALS9_ligand |
HSC(Nos)_target |
CD44_receptor |
1.194e-04 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| Monocytes(Nos)_source |
LGALS9_ligand |
HSC(Nos)_target |
CD44_receptor |
7.552e-04 |
0.02 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| HSC(Nos)_source |
LGALS9_ligand |
Monocytes(Nos)_target |
CD44_receptor |
7.391e-04 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| Monocytes(Nos)_source |
HLA-DPA1_ligand |
Monocytes(Nos)_target |
CD4_receptor |
3.737e-02 |
0.0 |
MHC-II |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
NCAM1_ligand |
HSC(Nos)_target |
NCAM1_receptor |
1.204e-05 |
0.0 |
NCAM |
Cell-Cell Contact |
KEGG: hsa04514 |