Sample overview
| Project Name | TCGA-HNSC |
| GSE ID | GSE164690 |
| GSM ID | GSM5017050 |
| Cell Line | None |
| Tissue type | Tumor |
| Disease Type | None |
| PMID | 34921143 |
| Initial gene number | 33545 |
| Initial cell number | 2604 |
| Post-QC gene number | 2383 |
| Post-QC cell number | 1958 |
QC Metrics
Bulk-to-ScRNA-seq Label Transfer
Bulk phenotype-associated subpopulations
Reference-Based Annotation
Differentially expressed genes
Overall Survival : Cluster vs
There are no results of the analysis here
Overall Survival : Cluster vs ( + )
There are no results of the analysis here
Clinical Stage : Cluster vs
There are no results of the analysis here
Tumor Size : Cluster vs
There are no results of the analysis here
Lymph Node Involvement : Cluster vs
There are no results of the analysis here
Distant Metastasis : Cluster vs
There are no results of the analysis here
Cell-Cell communications ( Survival-Associated Subpopulations Across Cell Types )
Cell Population Signaling and Communication
Ligand-Receptor-Mediated Cell-Cell Interactions
| Sending Cell Type | Ligand | Receiving Cell Type | Receptor | Score | P-value | Pathway Name | Function | Evidence |
|---|---|---|---|---|---|---|---|---|
| Endothelial,cells(Nos)_source | CCL2_ligand | Endothelial,cells(Nos)_target | ACKR1_receptor | 1.624e-03 | 0.0 | CCL | Secreted Signaling | PMID: 26740381 |
| Fibroblasts(Nos)_source | CCL2_ligand | Endothelial,cells(Nos)_target | ACKR1_receptor | 7.684e-04 | 0.0 | CCL | Secreted Signaling | PMID: 26740381 |
| Keratinocytes(Nos)_source | CCL2_ligand | Endothelial,cells(Nos)_target | ACKR1_receptor | 2.427e-05 | 0.0 | CCL | Secreted Signaling | PMID: 26740381 |
| Endothelial,cells(Nos)_source | CXCL2_ligand | Endothelial,cells(Nos)_target | ACKR1_receptor | 1.728e-03 | 0.0 | CXCL | Secreted Signaling | PMID: 26740381 |
| Keratinocytes(Nos)_source | CXCL2_ligand | Endothelial,cells(Nos)_target | ACKR1_receptor | 5.769e-05 | 0.0 | CXCL | Secreted Signaling | PMID: 26740381 |
| CD8+,T-cells(Nos)_source | MIF_ligand | CD8+,T-cells(Nos)_target | CD74_CXCR4_receptor | 3.233e-03 | 0.0 | MIF | Secreted Signaling | PMID: 29637711; PMID: 24760155 |
| Endothelial,cells(Nos)_source | MIF_ligand | CD8+,T-cells(Nos)_target | CD74_CXCR4_receptor | 5.663e-03 | 0.0 | MIF | Secreted Signaling | PMID: 29637711; PMID: 24760155 |
| Fibroblasts(Nos)_source | MIF_ligand | CD8+,T-cells(Nos)_target | CD74_CXCR4_receptor | 2.971e-03 | 0.0 | MIF | Secreted Signaling | PMID: 29637711; PMID: 24760155 |
| Keratinocytes(Nos)_source | MIF_ligand | CD8+,T-cells(Nos)_target | CD74_CXCR4_receptor | 2.427e-04 | 0.0 | MIF | Secreted Signaling | PMID: 29637711; PMID: 24760155 |
| Endothelial,cells(Nos)_source | MIF_ligand | Monocytes(Nos)_target | CD74_CXCR4_receptor | 8.045e-04 | 0.0 | MIF | Secreted Signaling | PMID: 29637711; PMID: 24760155 |
| Fibroblasts(Nos)_source | MIF_ligand | Monocytes(Nos)_target | CD74_CXCR4_receptor | 4.215e-04 | 0.0 | MIF | Secreted Signaling | PMID: 29637711; PMID: 24760155 |
| CD8+,T-cells(Nos)_source | MIF_ligand | CD8+,T-cells(Nos)_target | CD74_CD44_receptor | 2.446e-03 | 0.0 | MIF | Secreted Signaling | PMID: 29637711; PMID: 26175090 |
| Endothelial,cells(Nos)_source | MIF_ligand | CD8+,T-cells(Nos)_target | CD74_CD44_receptor | 4.299e-03 | 0.0 | MIF | Secreted Signaling | PMID: 29637711; PMID: 26175090 |
| Fibroblasts(Nos)_source | MIF_ligand | CD8+,T-cells(Nos)_target | CD74_CD44_receptor | 2.254e-03 | 0.0 | MIF | Secreted Signaling | PMID: 29637711; PMID: 26175090 |
| Keratinocytes(Nos)_source | MIF_ligand | CD8+,T-cells(Nos)_target | CD74_CD44_receptor | 1.838e-04 | 0.0 | MIF | Secreted Signaling | PMID: 29637711; PMID: 26175090 |
| Endothelial,cells(Nos)_source | MIF_ligand | Monocytes(Nos)_target | CD74_CD44_receptor | 7.758e-04 | 0.0 | MIF | Secreted Signaling | PMID: 29637711; PMID: 26175090 |
| Fibroblasts(Nos)_source | MIF_ligand | Monocytes(Nos)_target | CD74_CD44_receptor | 4.065e-04 | 0.0 | MIF | Secreted Signaling | PMID: 29637711; PMID: 26175090 |
| Keratinocytes(Nos)_source | MIF_ligand | Monocytes(Nos)_target | CD74_CD44_receptor | 3.308e-05 | 0.03 | MIF | Secreted Signaling | PMID: 29637711; PMID: 26175090 |
| Keratinocytes(Nos)_source | NAMPT_ligand | CD8+,T-cells(Nos)_target | ITGA5_ITGB1_receptor | 6.778e-05 | 0.03 | VISFATIN | Secreted Signaling | PMID: 28490838 |
| Endothelial,cells(Nos)_source | NAMPT_ligand | Endothelial,cells(Nos)_target | ITGA5_ITGB1_receptor | 1.540e-03 | 0.0 | VISFATIN | Secreted Signaling | PMID: 28490838 |
| Fibroblasts(Nos)_source | NAMPT_ligand | Endothelial,cells(Nos)_target | ITGA5_ITGB1_receptor | 6.773e-04 | 0.0 | VISFATIN | Secreted Signaling | PMID: 28490838 |
| Keratinocytes(Nos)_source | NAMPT_ligand | Endothelial,cells(Nos)_target | ITGA5_ITGB1_receptor | 3.050e-04 | 0.0 | VISFATIN | Secreted Signaling | PMID: 28490838 |
| Monocytes(Nos)_source | NAMPT_ligand | Endothelial,cells(Nos)_target | ITGA5_ITGB1_receptor | 3.575e-04 | 0.0 | VISFATIN | Secreted Signaling | PMID: 28490838 |
| Endothelial,cells(Nos)_source | NAMPT_ligand | Fibroblasts(Nos)_target | ITGA5_ITGB1_receptor | 8.223e-04 | 0.0 | VISFATIN | Secreted Signaling | PMID: 28490838 |
| Fibroblasts(Nos)_source | NAMPT_ligand | Fibroblasts(Nos)_target | ITGA5_ITGB1_receptor | 3.615e-04 | 0.0 | VISFATIN | Secreted Signaling | PMID: 28490838 |
| Keratinocytes(Nos)_source | NAMPT_ligand | Fibroblasts(Nos)_target | ITGA5_ITGB1_receptor | 1.630e-04 | 0.0 | VISFATIN | Secreted Signaling | PMID: 28490838 |
| Monocytes(Nos)_source | NAMPT_ligand | Fibroblasts(Nos)_target | ITGA5_ITGB1_receptor | 1.909e-04 | 0.0 | VISFATIN | Secreted Signaling | PMID: 28490838 |
| Keratinocytes(Nos)_source | NAMPT_ligand | Keratinocytes(Nos)_target | ITGA5_ITGB1_receptor | 9.898e-06 | 0.0 | VISFATIN | Secreted Signaling | PMID: 28490838 |
| Endothelial,cells(Nos)_source | ANGPT2_ligand | Endothelial,cells(Nos)_target | ITGA5_ITGB1_receptor | 1.416e-03 | 0.0 | ANGPT | Secreted Signaling | PMID: 20651738; PMID: 25635707 |
| Fibroblasts(Nos)_source | ANGPT2_ligand | Endothelial,cells(Nos)_target | ITGA5_ITGB1_receptor | 4.074e-04 | 0.0 | ANGPT | Secreted Signaling | PMID: 20651738; PMID: 25635707 |
| Endothelial,cells(Nos)_source | ANGPT2_ligand | Fibroblasts(Nos)_target | ITGA5_ITGB1_receptor | 7.557e-04 | 0.0 | ANGPT | Secreted Signaling | PMID: 20651738; PMID: 25635707 |
| Fibroblasts(Nos)_source | ANGPT2_ligand | Fibroblasts(Nos)_target | ITGA5_ITGB1_receptor | 2.174e-04 | 0.0 | ANGPT | Secreted Signaling | PMID: 20651738; PMID: 25635707 |
| Endothelial,cells(Nos)_source | ANGPT2_ligand | Keratinocytes(Nos)_target | ITGA5_ITGB1_receptor | 4.540e-05 | 0.0 | ANGPT | Secreted Signaling | PMID: 20651738; PMID: 25635707 |
| Endothelial,cells(Nos)_source | MDK_ligand | Endothelial,cells(Nos)_target | ITGA6_ITGB1_receptor | 4.724e-03 | 0.0 | MK | Secreted Signaling | PMID: 28356350 |
| Fibroblasts(Nos)_source | MDK_ligand | Endothelial,cells(Nos)_target | ITGA6_ITGB1_receptor | 2.318e-03 | 0.0 | MK | Secreted Signaling | PMID: 28356350 |
| Keratinocytes(Nos)_source | MDK_ligand | Endothelial,cells(Nos)_target | ITGA6_ITGB1_receptor | 3.488e-04 | 0.0 | MK | Secreted Signaling | PMID: 28356350 |
| Endothelial,cells(Nos)_source | MDK_ligand | Fibroblasts(Nos)_target | ITGA6_ITGB1_receptor | 2.402e-03 | 0.0 | MK | Secreted Signaling | PMID: 28356350 |
| Fibroblasts(Nos)_source | MDK_ligand | Fibroblasts(Nos)_target | ITGA6_ITGB1_receptor | 1.178e-03 | 0.0 | MK | Secreted Signaling | PMID: 28356350 |
| Keratinocytes(Nos)_source | MDK_ligand | Fibroblasts(Nos)_target | ITGA6_ITGB1_receptor | 1.775e-04 | 0.0 | MK | Secreted Signaling | PMID: 28356350 |
| Endothelial,cells(Nos)_source | MDK_ligand | Keratinocytes(Nos)_target | ITGA6_ITGB1_receptor | 1.964e-04 | 0.0 | MK | Secreted Signaling | PMID: 28356350 |
| Fibroblasts(Nos)_source | MDK_ligand | Keratinocytes(Nos)_target | ITGA6_ITGB1_receptor | 9.629e-05 | 0.0 | MK | Secreted Signaling | PMID: 28356350 |
| Keratinocytes(Nos)_source | MDK_ligand | Keratinocytes(Nos)_target | ITGA6_ITGB1_receptor | 1.455e-05 | 0.0 | MK | Secreted Signaling | PMID: 28356350 |
| Endothelial,cells(Nos)_source | MDK_ligand | CD8+,T-cells(Nos)_target | NCL_receptor | 1.397e-03 | 0.0 | MK | Secreted Signaling | PMID: 28356350 |
| Fibroblasts(Nos)_source | MDK_ligand | CD8+,T-cells(Nos)_target | NCL_receptor | 6.834e-04 | 0.0 | MK | Secreted Signaling | PMID: 28356350 |
| Endothelial,cells(Nos)_source | MDK_ligand | Endothelial,cells(Nos)_target | NCL_receptor | 3.393e-03 | 0.0 | MK | Secreted Signaling | PMID: 28356350 |
| Fibroblasts(Nos)_source | MDK_ligand | Endothelial,cells(Nos)_target | NCL_receptor | 1.663e-03 | 0.0 | MK | Secreted Signaling | PMID: 28356350 |
| Keratinocytes(Nos)_source | MDK_ligand | Endothelial,cells(Nos)_target | NCL_receptor | 2.514e-04 | 0.0 | MK | Secreted Signaling | PMID: 28356350 |
| Endothelial,cells(Nos)_source | MDK_ligand | Fibroblasts(Nos)_target | NCL_receptor | 2.105e-03 | 0.0 | MK | Secreted Signaling | PMID: 28356350 |
| Fibroblasts(Nos)_source | MDK_ligand | Fibroblasts(Nos)_target | NCL_receptor | 1.032e-03 | 0.0 | MK | Secreted Signaling | PMID: 28356350 |
| Keratinocytes(Nos)_source | MDK_ligand | Fibroblasts(Nos)_target | NCL_receptor | 1.558e-04 | 0.0 | MK | Secreted Signaling | PMID: 28356350 |
| Endothelial,cells(Nos)_source | LGALS9_ligand | CD8+,T-cells(Nos)_target | PTPRC_receptor | 3.431e-03 | 0.0 | GALECTIN | Secreted Signaling | PMID: 30120235 |
| Keratinocytes(Nos)_source | LGALS9_ligand | CD8+,T-cells(Nos)_target | PTPRC_receptor | 1.125e-04 | 0.0 | GALECTIN | Secreted Signaling | PMID: 30120235 |
| Endothelial,cells(Nos)_source | LGALS9_ligand | Monocytes(Nos)_target | PTPRC_receptor | 1.934e-04 | 0.0 | GALECTIN | Secreted Signaling | PMID: 30120235 |
| Endothelial,cells(Nos)_source | LGALS9_ligand | CD8+,T-cells(Nos)_target | CD44_receptor | 1.219e-03 | 0.0 | GALECTIN | Secreted Signaling | PMID: 25065622 |
| Keratinocytes(Nos)_source | LGALS9_ligand | CD8+,T-cells(Nos)_target | CD44_receptor | 3.965e-05 | 0.0 | GALECTIN | Secreted Signaling | PMID: 25065622 |
| Endothelial,cells(Nos)_source | LGALS9_ligand | Endothelial,cells(Nos)_target | CD44_receptor | 4.375e-06 | 0.0 | GALECTIN | Secreted Signaling | PMID: 25065622 |
| Endothelial,cells(Nos)_source | LGALS9_ligand | Fibroblasts(Nos)_target | CD44_receptor | 4.863e-04 | 0.0 | GALECTIN | Secreted Signaling | PMID: 25065622 |
| Keratinocytes(Nos)_source | LGALS9_ligand | Fibroblasts(Nos)_target | CD44_receptor | 1.579e-05 | 0.0 | GALECTIN | Secreted Signaling | PMID: 25065622 |
| Endothelial,cells(Nos)_source | LGALS9_ligand | Keratinocytes(Nos)_target | CD44_receptor | 1.442e-05 | 0.0 | GALECTIN | Secreted Signaling | PMID: 25065622 |
| Endothelial,cells(Nos)_source | LGALS9_ligand | Monocytes(Nos)_target | CD44_receptor | 9.251e-05 | 0.0 | GALECTIN | Secreted Signaling | PMID: 25065622 |
| Fibroblasts(Nos)_source | FN1_ligand | CD8+,T-cells(Nos)_target | ITGA5_ITGB1_receptor | 4.093e-04 | 0.0 | FN1 | ECM-Receptor | KEGG: hsa04512 |
| Endothelial,cells(Nos)_source | FN1_ligand | Endothelial,cells(Nos)_target | ITGA5_ITGB1_receptor | 1.605e-03 | 0.0 | FN1 | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | FN1_ligand | Endothelial,cells(Nos)_target | ITGA5_ITGB1_receptor | 1.864e-03 | 0.0 | FN1 | ECM-Receptor | KEGG: hsa04512 |
| Endothelial,cells(Nos)_source | FN1_ligand | Fibroblasts(Nos)_target | ITGA5_ITGB1_receptor | 8.567e-04 | 0.0 | FN1 | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | FN1_ligand | Fibroblasts(Nos)_target | ITGA5_ITGB1_receptor | 9.956e-04 | 0.0 | FN1 | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | FN1_ligand | Keratinocytes(Nos)_target | ITGA5_ITGB1_receptor | 6.010e-05 | 0.0 | FN1 | ECM-Receptor | KEGG: hsa04512 |
| Endothelial,cells(Nos)_source | LAMA4_ligand | Endothelial,cells(Nos)_target | ITGA6_ITGB1_receptor | 1.631e-03 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | LAMA4_ligand | Endothelial,cells(Nos)_target | ITGA6_ITGB1_receptor | 1.871e-03 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Endothelial,cells(Nos)_source | LAMA4_ligand | Fibroblasts(Nos)_target | ITGA6_ITGB1_receptor | 8.278e-04 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | LAMA4_ligand | Fibroblasts(Nos)_target | ITGA6_ITGB1_receptor | 9.506e-04 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Endothelial,cells(Nos)_source | LAMA4_ligand | Keratinocytes(Nos)_target | ITGA6_ITGB1_receptor | 6.749e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | LAMA4_ligand | Keratinocytes(Nos)_target | ITGA6_ITGB1_receptor | 7.764e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Endothelial,cells(Nos)_source | LAMB1_ligand | CD8+,T-cells(Nos)_target | ITGA6_ITGB1_receptor | 1.927e-04 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | LAMB1_ligand | CD8+,T-cells(Nos)_target | ITGA6_ITGB1_receptor | 9.722e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Endothelial,cells(Nos)_source | LAMB1_ligand | Endothelial,cells(Nos)_target | ITGA6_ITGB1_receptor | 1.033e-03 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | LAMB1_ligand | Endothelial,cells(Nos)_target | ITGA6_ITGB1_receptor | 5.215e-04 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Endothelial,cells(Nos)_source | LAMB1_ligand | Fibroblasts(Nos)_target | ITGA6_ITGB1_receptor | 5.242e-04 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | LAMB1_ligand | Fibroblasts(Nos)_target | ITGA6_ITGB1_receptor | 2.645e-04 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Endothelial,cells(Nos)_source | LAMB1_ligand | Keratinocytes(Nos)_target | ITGA6_ITGB1_receptor | 4.271e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | LAMB1_ligand | Keratinocytes(Nos)_target | ITGA6_ITGB1_receptor | 2.155e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Endothelial,cells(Nos)_source | LAMB1_ligand | Monocytes(Nos)_target | ITGA6_ITGB1_receptor | 2.951e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | LAMB1_ligand | Monocytes(Nos)_target | ITGA6_ITGB1_receptor | 1.488e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Endothelial,cells(Nos)_source | LAMB2_ligand | Endothelial,cells(Nos)_target | ITGA6_ITGB1_receptor | 1.227e-03 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | LAMB2_ligand | Endothelial,cells(Nos)_target | ITGA6_ITGB1_receptor | 7.655e-04 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Endothelial,cells(Nos)_source | LAMB2_ligand | Fibroblasts(Nos)_target | ITGA6_ITGB1_receptor | 6.225e-04 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | LAMB2_ligand | Fibroblasts(Nos)_target | ITGA6_ITGB1_receptor | 3.884e-04 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Endothelial,cells(Nos)_source | LAMB2_ligand | Keratinocytes(Nos)_target | ITGA6_ITGB1_receptor | 5.073e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | LAMB2_ligand | Keratinocytes(Nos)_target | ITGA6_ITGB1_receptor | 3.166e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Endothelial,cells(Nos)_source | LAMC1_ligand | Endothelial,cells(Nos)_target | ITGA6_ITGB1_receptor | 1.254e-03 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | LAMC1_ligand | Endothelial,cells(Nos)_target | ITGA6_ITGB1_receptor | 8.310e-04 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Endothelial,cells(Nos)_source | LAMC1_ligand | Fibroblasts(Nos)_target | ITGA6_ITGB1_receptor | 6.362e-04 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | LAMC1_ligand | Fibroblasts(Nos)_target | ITGA6_ITGB1_receptor | 4.217e-04 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Endothelial,cells(Nos)_source | LAMC1_ligand | Keratinocytes(Nos)_target | ITGA6_ITGB1_receptor | 5.185e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | LAMC1_ligand | Keratinocytes(Nos)_target | ITGA6_ITGB1_receptor | 3.437e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Endothelial,cells(Nos)_source | FN1_ligand | CD8+,T-cells(Nos)_target | CD44_receptor | 1.478e-03 | 0.0 | FN1 | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | FN1_ligand | CD8+,T-cells(Nos)_target | CD44_receptor | 1.714e-03 | 0.0 | FN1 | ECM-Receptor | KEGG: hsa04512 |
| Endothelial,cells(Nos)_source | FN1_ligand | Fibroblasts(Nos)_target | CD44_receptor | 5.901e-04 | 0.0 | FN1 | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | FN1_ligand | Fibroblasts(Nos)_target | CD44_receptor | 6.882e-04 | 0.0 | FN1 | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | FN1_ligand | Keratinocytes(Nos)_target | CD44_receptor | 2.054e-05 | 0.02 | FN1 | ECM-Receptor | KEGG: hsa04512 |
| Endothelial,cells(Nos)_source | FN1_ligand | Monocytes(Nos)_target | CD44_receptor | 1.123e-04 | 0.0 | FN1 | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | FN1_ligand | Monocytes(Nos)_target | CD44_receptor | 1.315e-04 | 0.0 | FN1 | ECM-Receptor | KEGG: hsa04512 |
| Endothelial,cells(Nos)_source | COL1A1_ligand | CD8+,T-cells(Nos)_target | CD44_receptor | 1.357e-03 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | COL1A1_ligand | CD8+,T-cells(Nos)_target | CD44_receptor | 3.647e-03 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| Endothelial,cells(Nos)_source | COL1A1_ligand | Fibroblasts(Nos)_target | CD44_receptor | 5.418e-04 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | COL1A1_ligand | Fibroblasts(Nos)_target | CD44_receptor | 1.484e-03 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | COL1A1_ligand | Keratinocytes(Nos)_target | CD44_receptor | 4.484e-05 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| Endothelial,cells(Nos)_source | COL1A1_ligand | Monocytes(Nos)_target | CD44_receptor | 1.031e-04 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | COL1A1_ligand | Monocytes(Nos)_target | CD44_receptor | 2.862e-04 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | COL1A2_ligand | CD8+,T-cells(Nos)_target | CD44_receptor | 6.359e-03 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | COL1A2_ligand | Fibroblasts(Nos)_target | CD44_receptor | 2.635e-03 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | COL1A2_ligand | Keratinocytes(Nos)_target | CD44_receptor | 8.111e-05 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | COL1A2_ligand | Monocytes(Nos)_target | CD44_receptor | 5.152e-04 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| Endothelial,cells(Nos)_source | COL4A1_ligand | CD8+,T-cells(Nos)_target | CD44_receptor | 4.256e-03 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | COL4A1_ligand | CD8+,T-cells(Nos)_target | CD44_receptor | 2.766e-03 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| Endothelial,cells(Nos)_source | COL4A1_ligand | Fibroblasts(Nos)_target | CD44_receptor | 1.717e-03 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | COL4A1_ligand | Fibroblasts(Nos)_target | CD44_receptor | 1.119e-03 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| Endothelial,cells(Nos)_source | COL4A1_ligand | Keratinocytes(Nos)_target | CD44_receptor | 5.146e-05 | 0.02 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | COL4A1_ligand | Keratinocytes(Nos)_target | CD44_receptor | 3.361e-05 | 0.02 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| Endothelial,cells(Nos)_source | COL4A1_ligand | Monocytes(Nos)_target | CD44_receptor | 3.292e-04 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | COL4A1_ligand | Monocytes(Nos)_target | CD44_receptor | 2.149e-04 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| Endothelial,cells(Nos)_source | COL4A2_ligand | CD8+,T-cells(Nos)_target | CD44_receptor | 4.415e-03 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | COL4A2_ligand | CD8+,T-cells(Nos)_target | CD44_receptor | 2.762e-03 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| Endothelial,cells(Nos)_source | COL4A2_ligand | Fibroblasts(Nos)_target | CD44_receptor | 1.782e-03 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | COL4A2_ligand | Fibroblasts(Nos)_target | CD44_receptor | 1.117e-03 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| Endothelial,cells(Nos)_source | COL4A2_ligand | Keratinocytes(Nos)_target | CD44_receptor | 5.344e-05 | 0.02 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | COL4A2_ligand | Keratinocytes(Nos)_target | CD44_receptor | 3.357e-05 | 0.03 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| Endothelial,cells(Nos)_source | COL4A2_ligand | Monocytes(Nos)_target | CD44_receptor | 3.419e-04 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | COL4A2_ligand | Monocytes(Nos)_target | CD44_receptor | 2.146e-04 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | COL6A1_ligand | CD8+,T-cells(Nos)_target | CD44_receptor | 4.662e-03 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | COL6A1_ligand | Fibroblasts(Nos)_target | CD44_receptor | 1.910e-03 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | COL6A1_ligand | Keratinocytes(Nos)_target | CD44_receptor | 5.811e-05 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | COL6A1_ligand | Monocytes(Nos)_target | CD44_receptor | 3.702e-04 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| Endothelial,cells(Nos)_source | COL6A2_ligand | CD8+,T-cells(Nos)_target | CD44_receptor | 1.337e-03 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | COL6A2_ligand | CD8+,T-cells(Nos)_target | CD44_receptor | 5.721e-03 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| Endothelial,cells(Nos)_source | COL6A2_ligand | Fibroblasts(Nos)_target | CD44_receptor | 5.336e-04 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | COL6A2_ligand | Fibroblasts(Nos)_target | CD44_receptor | 2.360e-03 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | COL6A2_ligand | Keratinocytes(Nos)_target | CD44_receptor | 7.233e-05 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | COL6A2_ligand | Monocytes(Nos)_target | CD44_receptor | 4.600e-04 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | COL6A3_ligand | CD8+,T-cells(Nos)_target | CD44_receptor | 2.926e-03 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | COL6A3_ligand | Endothelial,cells(Nos)_target | CD44_receptor | 1.088e-05 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | COL6A3_ligand | Fibroblasts(Nos)_target | CD44_receptor | 1.185e-03 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | COL6A3_ligand | Keratinocytes(Nos)_target | CD44_receptor | 3.564e-05 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | COL6A3_ligand | Monocytes(Nos)_target | CD44_receptor | 2.278e-04 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| Endothelial,cells(Nos)_source | LAMA4_ligand | CD8+,T-cells(Nos)_target | CD44_receptor | 1.489e-03 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | LAMA4_ligand | CD8+,T-cells(Nos)_target | CD44_receptor | 1.706e-03 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Endothelial,cells(Nos)_source | LAMA4_ligand | Fibroblasts(Nos)_target | CD44_receptor | 5.948e-04 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | LAMA4_ligand | Fibroblasts(Nos)_target | CD44_receptor | 6.851e-04 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | LAMA4_ligand | Keratinocytes(Nos)_target | CD44_receptor | 2.045e-05 | 0.03 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Endothelial,cells(Nos)_source | LAMA4_ligand | Monocytes(Nos)_target | CD44_receptor | 1.132e-04 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | LAMA4_ligand | Monocytes(Nos)_target | CD44_receptor | 1.310e-04 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Endothelial,cells(Nos)_source | LAMB1_ligand | CD8+,T-cells(Nos)_target | CD44_receptor | 9.439e-04 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | LAMB1_ligand | CD8+,T-cells(Nos)_target | CD44_receptor | 4.764e-04 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Endothelial,cells(Nos)_source | LAMB1_ligand | Endothelial,cells(Nos)_target | CD44_receptor | 3.380e-06 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | LAMB1_ligand | Endothelial,cells(Nos)_target | CD44_receptor | 1.704e-06 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Endothelial,cells(Nos)_source | LAMB1_ligand | Fibroblasts(Nos)_target | CD44_receptor | 3.762e-04 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | LAMB1_ligand | Fibroblasts(Nos)_target | CD44_receptor | 1.898e-04 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Endothelial,cells(Nos)_source | LAMB1_ligand | Keratinocytes(Nos)_target | CD44_receptor | 1.114e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | LAMB1_ligand | Keratinocytes(Nos)_target | CD44_receptor | 5.621e-06 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Endothelial,cells(Nos)_source | LAMB1_ligand | Monocytes(Nos)_target | CD44_receptor | 7.151e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | LAMB1_ligand | Monocytes(Nos)_target | CD44_receptor | 3.607e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Endothelial,cells(Nos)_source | LAMB2_ligand | CD8+,T-cells(Nos)_target | CD44_receptor | 1.121e-03 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | LAMB2_ligand | CD8+,T-cells(Nos)_target | CD44_receptor | 6.991e-04 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Endothelial,cells(Nos)_source | LAMB2_ligand | Fibroblasts(Nos)_target | CD44_receptor | 4.469e-04 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | LAMB2_ligand | Fibroblasts(Nos)_target | CD44_receptor | 2.789e-04 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Endothelial,cells(Nos)_source | LAMB2_ligand | Keratinocytes(Nos)_target | CD44_receptor | 1.325e-05 | 0.03 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Endothelial,cells(Nos)_source | LAMB2_ligand | Monocytes(Nos)_target | CD44_receptor | 8.500e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | LAMB2_ligand | Monocytes(Nos)_target | CD44_receptor | 5.307e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Endothelial,cells(Nos)_source | LAMC1_ligand | CD8+,T-cells(Nos)_target | CD44_receptor | 1.145e-03 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | LAMC1_ligand | CD8+,T-cells(Nos)_target | CD44_receptor | 7.589e-04 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Endothelial,cells(Nos)_source | LAMC1_ligand | Fibroblasts(Nos)_target | CD44_receptor | 4.568e-04 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | LAMC1_ligand | Fibroblasts(Nos)_target | CD44_receptor | 3.029e-04 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Endothelial,cells(Nos)_source | LAMC1_ligand | Monocytes(Nos)_target | CD44_receptor | 8.687e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Fibroblasts(Nos)_source | LAMC1_ligand | Monocytes(Nos)_target | CD44_receptor | 5.764e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Endothelial,cells(Nos)_source | APP_ligand | CD8+,T-cells(Nos)_target | CD74_receptor | 5.434e-03 | 0.0 | APP | Cell-Cell Contact | PMID: 19849849 |
| Endothelial,cells(Nos)_source | APP_ligand | Endothelial,cells(Nos)_target | CD74_receptor | 8.391e-03 | 0.0 | APP | Cell-Cell Contact | PMID: 19849849 |
| Fibroblasts(Nos)_source | APP_ligand | Endothelial,cells(Nos)_target | CD74_receptor | 2.497e-03 | 0.0 | APP | Cell-Cell Contact | PMID: 19849849 |
| Keratinocytes(Nos)_source | APP_ligand | Endothelial,cells(Nos)_target | CD74_receptor | 2.449e-04 | 0.03 | APP | Cell-Cell Contact | PMID: 19849849 |
| Endothelial,cells(Nos)_source | APP_ligand | Keratinocytes(Nos)_target | CD74_receptor | 2.356e-04 | 0.01 | APP | Cell-Cell Contact | PMID: 19849849 |
| Endothelial,cells(Nos)_source | APP_ligand | Monocytes(Nos)_target | CD74_receptor | 2.232e-03 | 0.0 | APP | Cell-Cell Contact | PMID: 19849849 |
| Fibroblasts(Nos)_source | APP_ligand | Monocytes(Nos)_target | CD74_receptor | 6.686e-04 | 0.0 | APP | Cell-Cell Contact | PMID: 19849849 |
| Keratinocytes(Nos)_source | APP_ligand | Monocytes(Nos)_target | CD74_receptor | 6.557e-05 | 0.0 | APP | Cell-Cell Contact | PMID: 19849849 |
| Endothelial,cells(Nos)_source | CD99_ligand | Endothelial,cells(Nos)_target | CD99_receptor | 2.858e-02 | 0.0 | CD99 | Cell-Cell Contact | KEGG: hsa04514 |
| Fibroblasts(Nos)_source | CD99_ligand | Endothelial,cells(Nos)_target | CD99_receptor | 1.364e-02 | 0.0 | CD99 | Cell-Cell Contact | KEGG: hsa04514 |
| Endothelial,cells(Nos)_source | CD99_ligand | Fibroblasts(Nos)_target | CD99_receptor | 1.364e-02 | 0.0 | CD99 | Cell-Cell Contact | KEGG: hsa04514 |
| Endothelial,cells(Nos)_source | CDH5_ligand | CD8+,T-cells(Nos)_target | CDH5_receptor | 5.137e-07 | 0.0 | CDH5 | Cell-Cell Contact | KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source | CDH5_ligand | Endothelial,cells(Nos)_target | CDH5_receptor | 5.137e-07 | 0.0 | CDH5 | Cell-Cell Contact | KEGG: hsa04514 |
| Endothelial,cells(Nos)_source | CDH5_ligand | Endothelial,cells(Nos)_target | CDH5_receptor | 1.179e-03 | 0.0 | CDH5 | Cell-Cell Contact | KEGG: hsa04514 |
| Fibroblasts(Nos)_source | CDH5_ligand | Endothelial,cells(Nos)_target | CDH5_receptor | 2.688e-06 | 0.0 | CDH5 | Cell-Cell Contact | KEGG: hsa04514 |
| Endothelial,cells(Nos)_source | CDH5_ligand | Fibroblasts(Nos)_target | CDH5_receptor | 2.688e-06 | 0.0 | CDH5 | Cell-Cell Contact | KEGG: hsa04514 |
| Endothelial,cells(Nos)_source | ESAM_ligand | Endothelial,cells(Nos)_target | ESAM_receptor | 1.097e-03 | 0.0 | ESAM | Cell-Cell Contact | KEGG: hsa04514; PMID: 11279107 |
| Fibroblasts(Nos)_source | ESAM_ligand | Endothelial,cells(Nos)_target | ESAM_receptor | 5.076e-04 | 0.0 | ESAM | Cell-Cell Contact | KEGG: hsa04514; PMID: 11279107 |
| Endothelial,cells(Nos)_source | ESAM_ligand | Fibroblasts(Nos)_target | ESAM_receptor | 5.076e-04 | 0.0 | ESAM | Cell-Cell Contact | KEGG: hsa04514; PMID: 11279107 |
| Fibroblasts(Nos)_source | ESAM_ligand | Fibroblasts(Nos)_target | ESAM_receptor | 2.348e-04 | 0.0 | ESAM | Cell-Cell Contact | KEGG: hsa04514; PMID: 11279107 |
| Endothelial,cells(Nos)_source | PECAM1_ligand | Endothelial,cells(Nos)_target | PECAM1_receptor | 1.035e-02 | 0.0 | PECAM1 | Cell-Cell Contact | KEGG: hsa04514 |