Sample overview
| Project Name |
TCGA-HNSC
|
| GSE ID |
GSE164690
|
| GSM ID |
GSM5017025
|
| Cell Line |
None
|
| Tissue type |
Tumor
|
| Disease Type |
None
|
| PMID |
34921143
|
| Initial gene number |
33545
|
| Initial cell number |
1221
|
| Post-QC gene number |
1249
|
| Post-QC cell number |
623
|
Bulk-to-ScRNA-seq Label Transfer
Bulk phenotype-associated subpopulations
Reference-Based Annotation
Differentially expressed genes
Overall Survival : Cluster
vs
There are no results of the analysis here
Overall Survival : Cluster
vs ( + )
There are no results of the analysis here
Clinical Stage : Cluster
vs
There
are no results of the analysis here
Tumor Size : Cluster
vs
There
are no results of the analysis here
Lymph Node Involvement : Cluster
vs
There
are no results of the analysis here
Distant Metastasis : Cluster
vs
There
are no results of the analysis here
Cell-Cell communications ( Survival-Associated Subpopulations Across Cell Types )
Cell Population Signaling and Communication
Ligand-Receptor-Mediated Cell-Cell Interactions
| Sending Cell Type |
Ligand |
Receiving Cell Type |
Receptor |
Score |
P-value |
Pathway Name |
Function |
Evidence |
| B-cells(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CXCR4_receptor |
2.143e-05 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| CD8+,T-cells(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CXCR4_receptor |
2.870e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| Macrophages(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CXCR4_receptor |
2.883e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| Monocytes(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CXCR4_receptor |
3.338e-05 |
0.01 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| Macrophages(Nos)_source |
MIF_ligand |
CD4+,T-cells(Nos)_target |
CD74_CXCR4_receptor |
2.052e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| B-cells(Nos)_source |
MIF_ligand |
CD8+,T-cells(Nos)_target |
CD74_CXCR4_receptor |
2.402e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| CD8+,T-cells(Nos)_source |
MIF_ligand |
CD8+,T-cells(Nos)_target |
CD74_CXCR4_receptor |
3.213e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| Macrophages(Nos)_source |
MIF_ligand |
CD8+,T-cells(Nos)_target |
CD74_CXCR4_receptor |
3.253e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| Macrophages(Nos)_source |
MIF_ligand |
Macrophages(Nos)_target |
CD74_CXCR4_receptor |
1.101e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| CD8+,T-cells(Nos)_source |
MIF_ligand |
CD8+,T-cells(Nos)_target |
CD74_CD44_receptor |
2.537e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Macrophages(Nos)_source |
MIF_ligand |
CD8+,T-cells(Nos)_target |
CD74_CD44_receptor |
2.583e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| B-cells(Nos)_source |
MIF_ligand |
Macrophages(Nos)_target |
CD74_CD44_receptor |
1.506e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| CD8+,T-cells(Nos)_source |
MIF_ligand |
Macrophages(Nos)_target |
CD74_CD44_receptor |
2.015e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Macrophages(Nos)_source |
MIF_ligand |
Macrophages(Nos)_target |
CD74_CD44_receptor |
2.040e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Macrophages(Nos)_source |
MIF_ligand |
Monocytes(Good)_target |
CD74_CD44_receptor |
4.149e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| B-cells(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
3.500e-05 |
0.01 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| CD8+,T-cells(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
4.681e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Macrophages(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
4.747e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Macrophages(Nos)_source |
SPP1_ligand |
CD8+,T-cells(Nos)_target |
CD44_receptor |
6.481e-03 |
0.0 |
SPP1 |
Secreted Signaling |
PMID: 21907263 |
| Monocytes(Good)_source |
SPP1_ligand |
CD8+,T-cells(Nos)_target |
CD44_receptor |
8.512e-04 |
0.01 |
SPP1 |
Secreted Signaling |
PMID: 21907263 |
| CD8+,T-cells(Nos)_source |
SPP1_ligand |
Macrophages(Nos)_target |
CD44_receptor |
2.928e-03 |
0.0 |
SPP1 |
Secreted Signaling |
PMID: 21907263 |
| Macrophages(Nos)_source |
SPP1_ligand |
Macrophages(Nos)_target |
CD44_receptor |
4.610e-03 |
0.0 |
SPP1 |
Secreted Signaling |
PMID: 21907263 |
| Monocytes(Good)_source |
SPP1_ligand |
Macrophages(Nos)_target |
CD44_receptor |
6.124e-04 |
0.0 |
SPP1 |
Secreted Signaling |
PMID: 21907263 |
| Monocytes(Nos)_source |
SPP1_ligand |
Macrophages(Nos)_target |
CD44_receptor |
4.990e-04 |
0.03 |
SPP1 |
Secreted Signaling |
PMID: 21907263 |
| NK,cells(Nos)_source |
SPP1_ligand |
Macrophages(Nos)_target |
CD44_receptor |
1.036e-03 |
0.0 |
SPP1 |
Secreted Signaling |
PMID: 21907263 |
| Macrophages(Nos)_source |
SPP1_ligand |
Monocytes(Good)_target |
CD44_receptor |
1.090e-03 |
0.0 |
SPP1 |
Secreted Signaling |
PMID: 21907263 |
| Macrophages(Nos)_source |
SPP1_ligand |
Monocytes(Nos)_target |
CD44_receptor |
1.170e-03 |
0.0 |
SPP1 |
Secreted Signaling |
PMID: 21907263 |
| Monocytes(Good)_source |
SPP1_ligand |
Monocytes(Nos)_target |
CD44_receptor |
1.559e-04 |
0.01 |
SPP1 |
Secreted Signaling |
PMID: 21907263 |
| NK,cells(Nos)_source |
SPP1_ligand |
Monocytes(Nos)_target |
CD44_receptor |
2.637e-04 |
0.03 |
SPP1 |
Secreted Signaling |
PMID: 21907263 |
| B-cells(Nos)_source |
LGALS9_ligand |
CD4+,T-cells(Nos)_target |
PTPRC_receptor |
3.468e-04 |
0.01 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| Macrophages(Nos)_source |
LGALS9_ligand |
CD4+,T-cells(Nos)_target |
PTPRC_receptor |
3.582e-03 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| B-cells(Nos)_source |
LGALS9_ligand |
CD8+,T-cells(Nos)_target |
PTPRC_receptor |
4.331e-04 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| Macrophages(Nos)_source |
LGALS9_ligand |
CD8+,T-cells(Nos)_target |
PTPRC_receptor |
4.458e-03 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| Monocytes(Good)_source |
LGALS9_ligand |
CD8+,T-cells(Nos)_target |
PTPRC_receptor |
3.471e-04 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| Monocytes(Nos)_source |
LGALS9_ligand |
CD8+,T-cells(Nos)_target |
PTPRC_receptor |
3.009e-04 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| B-cells(Nos)_source |
LGALS9_ligand |
Macrophages(Nos)_target |
PTPRC_receptor |
1.221e-04 |
0.03 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| Macrophages(Nos)_source |
LGALS9_ligand |
Macrophages(Nos)_target |
PTPRC_receptor |
1.265e-03 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| B-cells(Nos)_source |
LGALS9_ligand |
Monocytes(Good)_target |
PTPRC_receptor |
6.349e-05 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| Macrophages(Nos)_source |
LGALS9_ligand |
Monocytes(Good)_target |
PTPRC_receptor |
6.550e-04 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| B-cells(Nos)_source |
LGALS9_ligand |
Monocytes(Nos)_target |
PTPRC_receptor |
6.046e-05 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| Macrophages(Nos)_source |
LGALS9_ligand |
Monocytes(Nos)_target |
PTPRC_receptor |
6.229e-04 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| Monocytes(Nos)_source |
LGALS9_ligand |
Monocytes(Nos)_target |
PTPRC_receptor |
4.175e-05 |
0.01 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| B-cells(Nos)_source |
LGALS9_ligand |
NK,cells(Nos)_target |
PTPRC_receptor |
9.199e-05 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| Macrophages(Nos)_source |
LGALS9_ligand |
NK,cells(Nos)_target |
PTPRC_receptor |
9.510e-04 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| Macrophages(Nos)_source |
LGALS9_ligand |
CD4+,T-cells(Nos)_target |
CD44_receptor |
8.014e-04 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| B-cells(Nos)_source |
LGALS9_ligand |
CD8+,T-cells(Nos)_target |
CD44_receptor |
2.507e-04 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| Macrophages(Nos)_source |
LGALS9_ligand |
CD8+,T-cells(Nos)_target |
CD44_receptor |
2.593e-03 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| Monocytes(Good)_source |
LGALS9_ligand |
CD8+,T-cells(Nos)_target |
CD44_receptor |
1.959e-04 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| Monocytes(Nos)_source |
LGALS9_ligand |
CD8+,T-cells(Nos)_target |
CD44_receptor |
1.699e-04 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| B-cells(Nos)_source |
LGALS9_ligand |
Macrophages(Nos)_target |
CD44_receptor |
1.808e-04 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| Macrophages(Nos)_source |
LGALS9_ligand |
Macrophages(Nos)_target |
CD44_receptor |
1.868e-03 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| Monocytes(Good)_source |
LGALS9_ligand |
Macrophages(Nos)_target |
CD44_receptor |
1.420e-04 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| Monocytes(Nos)_source |
LGALS9_ligand |
Macrophages(Nos)_target |
CD44_receptor |
1.231e-04 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| B-cells(Nos)_source |
LGALS9_ligand |
Monocytes(Good)_target |
CD44_receptor |
4.183e-05 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| Macrophages(Nos)_source |
LGALS9_ligand |
Monocytes(Good)_target |
CD44_receptor |
4.329e-04 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| B-cells(Nos)_source |
LGALS9_ligand |
Monocytes(Nos)_target |
CD44_receptor |
4.602e-05 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| Macrophages(Nos)_source |
LGALS9_ligand |
Monocytes(Nos)_target |
CD44_receptor |
4.754e-04 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| Monocytes(Good)_source |
LGALS9_ligand |
Monocytes(Nos)_target |
CD44_receptor |
3.618e-05 |
0.02 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| Monocytes(Nos)_source |
LGALS9_ligand |
Monocytes(Nos)_target |
CD44_receptor |
3.137e-05 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| Macrophages(Nos)_source |
FN1_ligand |
CD4+,T-cells(Nos)_target |
CD44_receptor |
5.670e-04 |
0.0 |
FN1 |
ECM-Receptor |
KEGG: hsa04512 |
| Macrophages(Nos)_source |
FN1_ligand |
CD8+,T-cells(Nos)_target |
CD44_receptor |
1.856e-03 |
0.0 |
FN1 |
ECM-Receptor |
KEGG: hsa04512 |
| Macrophages(Nos)_source |
FN1_ligand |
Macrophages(Nos)_target |
CD44_receptor |
1.340e-03 |
0.0 |
FN1 |
ECM-Receptor |
KEGG: hsa04512 |
| Macrophages(Nos)_source |
FN1_ligand |
Monocytes(Good)_target |
CD44_receptor |
3.094e-04 |
0.0 |
FN1 |
ECM-Receptor |
KEGG: hsa04512 |
| Macrophages(Nos)_source |
FN1_ligand |
Monocytes(Nos)_target |
CD44_receptor |
3.413e-04 |
0.0 |
FN1 |
ECM-Receptor |
KEGG: hsa04512 |
| Macrophages(Nos)_source |
CD99_ligand |
CD8+,T-cells(Nos)_target |
CD99_receptor |
3.324e-03 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| NK,cells(Nos)_source |
CD99_ligand |
CD8+,T-cells(Nos)_target |
CD99_receptor |
1.814e-03 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
CD99_ligand |
Macrophages(Nos)_target |
CD99_receptor |
3.324e-03 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Macrophages(Nos)_source |
CD99_ligand |
Macrophages(Nos)_target |
CD99_receptor |
2.847e-03 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
CD99_ligand |
Macrophages(Nos)_target |
CD99_receptor |
4.768e-04 |
0.01 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| NK,cells(Nos)_source |
CD99_ligand |
Macrophages(Nos)_target |
CD99_receptor |
1.554e-03 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Macrophages(Nos)_source |
CD99_ligand |
Monocytes(Nos)_target |
CD99_receptor |
4.768e-04 |
0.01 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
CD99_ligand |
NK,cells(Nos)_target |
CD99_receptor |
1.814e-03 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Macrophages(Nos)_source |
CD99_ligand |
NK,cells(Nos)_target |
CD99_receptor |
1.554e-03 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| NK,cells(Nos)_source |
CD99_ligand |
NK,cells(Nos)_target |
CD99_receptor |
8.481e-04 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |