Sample overview
| Project Name |
TCGA-HNSC
|
| GSE ID |
GSE164690
|
| GSM ID |
GSM5017021
|
| Cell Line |
None
|
| Tissue type |
PBL
|
| Disease Type |
None
|
| PMID |
34921143
|
| Initial gene number |
33545
|
| Initial cell number |
1926
|
| Post-QC gene number |
1259
|
| Post-QC cell number |
967
|
Bulk-to-ScRNA-seq Label Transfer
Bulk phenotype-associated subpopulations
Reference-Based Annotation
Differentially expressed genes
Overall Survival : Cluster
vs
There are no results of the analysis here
Overall Survival : Cluster
vs ( + )
There are no results of the analysis here
Clinical Stage : Cluster
vs
There
are no results of the analysis here
Tumor Size : Cluster
vs
There
are no results of the analysis here
Lymph Node Involvement : Cluster
vs
There
are no results of the analysis here
Distant Metastasis : Cluster
vs
There
are no results of the analysis here
Cell-Cell communications ( Survival-Associated Subpopulations Across Cell Types )
Cell Population Signaling and Communication
Ligand-Receptor-Mediated Cell-Cell Interactions
| Sending Cell Type |
Ligand |
Receiving Cell Type |
Receptor |
Score |
P-value |
Pathway Name |
Function |
Evidence |
| B-cells(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CXCR4_receptor |
1.267e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| CD4+,T-cells(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CXCR4_receptor |
2.793e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| CD8+,T-cells(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CXCR4_receptor |
7.297e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| Monocytes(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CXCR4_receptor |
9.659e-05 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| NK,cells(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CXCR4_receptor |
4.872e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| CD4+,T-cells(Nos)_source |
MIF_ligand |
CD8+,T-cells(Nos)_target |
CD74_CXCR4_receptor |
6.585e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| CD8+,T-cells(Nos)_source |
MIF_ligand |
CD8+,T-cells(Nos)_target |
CD74_CXCR4_receptor |
1.720e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| NK,cells(Nos)_source |
MIF_ligand |
CD8+,T-cells(Nos)_target |
CD74_CXCR4_receptor |
1.141e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| CD4+,T-cells(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CXCR4_receptor |
1.229e-03 |
0.02 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| CD8+,T-cells(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CXCR4_receptor |
3.212e-04 |
0.02 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| CD4+,T-cells(Nos)_source |
MIF_ligand |
CD8+,T-cells(Nos)_target |
CD74_CD44_receptor |
4.875e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| CD8+,T-cells(Nos)_source |
MIF_ligand |
CD8+,T-cells(Nos)_target |
CD74_CD44_receptor |
1.274e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| B-cells(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
6.705e-05 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| CD4+,T-cells(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
1.493e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| CD8+,T-cells(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
3.901e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Monocytes(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
5.111e-05 |
0.04 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| NK,cells(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
2.593e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| CD8+,T-cells(Nos)_source |
CD99_ligand |
CD4+,T-cells(Nos)_target |
CD99_receptor |
1.337e-02 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| NK,cells(Nos)_source |
CD99_ligand |
CD4+,T-cells(Nos)_target |
CD99_receptor |
1.189e-02 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD4+,T-cells(Nos)_source |
CD99_ligand |
CD8+,T-cells(Nos)_target |
CD99_receptor |
1.337e-02 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
CD99_ligand |
CD8+,T-cells(Nos)_target |
CD99_receptor |
5.450e-03 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
CD99_ligand |
CD8+,T-cells(Nos)_target |
CD99_receptor |
6.177e-04 |
0.04 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| NK,cells(Nos)_source |
CD99_ligand |
CD8+,T-cells(Nos)_target |
CD99_receptor |
4.775e-03 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
CD99_ligand |
Monocytes(Nos)_target |
CD99_receptor |
6.177e-04 |
0.04 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| NK,cells(Nos)_source |
CD99_ligand |
Monocytes(Nos)_target |
CD99_receptor |
5.496e-04 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD4+,T-cells(Nos)_source |
CD99_ligand |
NK,cells(Nos)_target |
CD99_receptor |
1.189e-02 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
CD99_ligand |
NK,cells(Nos)_target |
CD99_receptor |
4.775e-03 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
CD99_ligand |
NK,cells(Nos)_target |
CD99_receptor |
5.496e-04 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| NK,cells(Nos)_source |
CD99_ligand |
NK,cells(Nos)_target |
CD99_receptor |
4.156e-03 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Nos)_source |
CLEC2D_ligand |
NK,cells(Nos)_target |
KLRB1_receptor |
4.140e-04 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| CD4+,T-cells(Nos)_source |
CLEC2D_ligand |
NK,cells(Nos)_target |
KLRB1_receptor |
5.892e-03 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| CD8+,T-cells(Nos)_source |
CLEC2D_ligand |
NK,cells(Nos)_target |
KLRB1_receptor |
1.802e-03 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| NK,cells(Nos)_source |
CLEC2D_ligand |
NK,cells(Nos)_target |
KLRB1_receptor |
1.359e-03 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| CD8+,T-cells(Nos)_source |
CLEC2B_ligand |
CD8+,T-cells(Nos)_target |
KLRB1_receptor |
3.897e-04 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| NK,cells(Nos)_source |
CLEC2B_ligand |
CD8+,T-cells(Nos)_target |
KLRB1_receptor |
3.150e-04 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| CD8+,T-cells(Nos)_source |
CLEC2B_ligand |
NK,cells(Nos)_target |
KLRB1_receptor |
1.750e-03 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| Monocytes(Nos)_source |
CLEC2B_ligand |
NK,cells(Nos)_target |
KLRB1_receptor |
2.446e-04 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| NK,cells(Nos)_source |
CLEC2B_ligand |
NK,cells(Nos)_target |
KLRB1_receptor |
1.408e-03 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| B-cells(Nos)_source |
CD69_ligand |
NK,cells(Nos)_target |
KLRB1_receptor |
4.398e-04 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| CD4+,T-cells(Nos)_source |
CD69_ligand |
NK,cells(Nos)_target |
KLRB1_receptor |
6.471e-03 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| CD8+,T-cells(Nos)_source |
CD69_ligand |
NK,cells(Nos)_target |
KLRB1_receptor |
1.801e-03 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| NK,cells(Nos)_source |
CD69_ligand |
NK,cells(Nos)_target |
KLRB1_receptor |
1.343e-03 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| Monocytes(Nos)_source |
SELPLG_ligand |
B-cells(Nos)_target |
SELL_receptor |
3.961e-05 |
0.0 |
SELPLG |
Cell-Cell Contact |
PMC2431087; PMID: 8892633,PMID: 8896607 |
| NK,cells(Nos)_source |
SELPLG_ligand |
B-cells(Nos)_target |
SELL_receptor |
1.219e-04 |
0.0 |
SELPLG |
Cell-Cell Contact |
PMC2431087; PMID: 8892633,PMID: 8896607 |
| CD4+,T-cells(Nos)_source |
SELPLG_ligand |
CD4+,T-cells(Nos)_target |
SELL_receptor |
5.820e-03 |
0.0 |
SELPLG |
Cell-Cell Contact |
PMC2431087; PMID: 8892633,PMID: 8896607 |
| Monocytes(Nos)_source |
SELPLG_ligand |
CD4+,T-cells(Nos)_target |
SELL_receptor |
5.913e-04 |
0.0 |
SELPLG |
Cell-Cell Contact |
PMC2431087; PMID: 8892633,PMID: 8896607 |
| NK,cells(Nos)_source |
SELPLG_ligand |
CD4+,T-cells(Nos)_target |
SELL_receptor |
1.819e-03 |
0.0 |
SELPLG |
Cell-Cell Contact |
PMC2431087; PMID: 8892633,PMID: 8896607 |