Sample overview
| Project Name |
TCGA-HNSC
|
| GSE ID |
GSE153559
|
| GSM ID |
GSM4647123
|
| Cell Line |
None
|
| Tissue type |
metastatic lymph node
|
| Disease Type |
HPV+ HNSCC
|
| PMID |
33208941
|
| Initial gene number |
33538
|
| Initial cell number |
1440
|
| Post-QC gene number |
3398
|
| Post-QC cell number |
880
|
Bulk-to-ScRNA-seq Label Transfer
Bulk phenotype-associated subpopulations
Reference-Based Annotation
Differentially expressed genes
Overall Survival : Cluster
vs
There are no results of the analysis here
Overall Survival : Cluster
vs ( + )
There are no results of the analysis here
Clinical Stage : Cluster
vs
There
are no results of the analysis here
Tumor Size : Cluster
vs
There
are no results of the analysis here
Lymph Node Involvement : Cluster
vs
There
are no results of the analysis here
Distant Metastasis : Cluster
vs
There
are no results of the analysis here
Cell-Cell communications ( Survival-Associated Subpopulations Across Cell Types )
Cell Population Signaling and Communication
Ligand-Receptor-Mediated Cell-Cell Interactions
| Sending Cell Type |
Ligand |
Receiving Cell Type |
Receptor |
Score |
P-value |
Pathway Name |
Function |
Evidence |
| B-cells(Good)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CXCR4_receptor |
6.766e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| Monocytes(Poor)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CXCR4_receptor |
1.221e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| Monocytes(Poor)_source |
MIF_ligand |
CD8+,T-cells(Nos)_target |
CD74_CXCR4_receptor |
1.010e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| B-cells(Good)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CXCR4_receptor |
2.787e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| Monocytes(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CXCR4_receptor |
7.402e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| Monocytes(Poor)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CXCR4_receptor |
5.025e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| B-cells(Good)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CD44_receptor |
6.240e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Monocytes(Poor)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CD44_receptor |
1.129e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Monocytes(Poor)_source |
MIF_ligand |
CD8+,T-cells(Nos)_target |
CD74_CD44_receptor |
1.021e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| B-cells(Good)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
2.613e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Monocytes(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
6.932e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Monocytes(Poor)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
4.719e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Monocytes(Nos)_source |
CD70_ligand |
B-cells(Good)_target |
CD27_receptor |
4.405e-04 |
0.0 |
CD70 |
Secreted Signaling |
KEGG: hsa04060 |
| Monocytes(Nos)_source |
CD70_ligand |
B-cells(Nos)_target |
CD27_receptor |
3.557e-03 |
0.0 |
CD70 |
Secreted Signaling |
KEGG: hsa04060 |
| Monocytes(Poor)_source |
CD70_ligand |
B-cells(Nos)_target |
CD27_receptor |
1.890e-04 |
0.02 |
CD70 |
Secreted Signaling |
KEGG: hsa04060 |
| CD8+,T-cells(Nos)_source |
ADGRE5_ligand |
B-cells(Nos)_target |
CD55_receptor |
2.171e-03 |
0.02 |
ADGRE5 |
Cell-Cell Contact |
PMID: 11297558 |
| B-cells(Nos)_source |
ADGRE5_ligand |
Monocytes(Nos)_target |
CD55_receptor |
1.000e-02 |
0.0 |
ADGRE5 |
Cell-Cell Contact |
PMID: 11297558 |
| CD8+,T-cells(Nos)_source |
ADGRE5_ligand |
Monocytes(Nos)_target |
CD55_receptor |
1.100e-03 |
0.0 |
ADGRE5 |
Cell-Cell Contact |
PMID: 11297558 |
| Monocytes(Nos)_source |
ADGRE5_ligand |
Monocytes(Nos)_target |
CD55_receptor |
4.348e-03 |
0.0 |
ADGRE5 |
Cell-Cell Contact |
PMID: 11297558 |
| B-cells(Nos)_source |
CD99_ligand |
B-cells(Nos)_target |
CD99_receptor |
8.220e-02 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
CD99_ligand |
B-cells(Nos)_target |
CD99_receptor |
3.219e-02 |
0.01 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Nos)_source |
CD99_ligand |
Monocytes(Nos)_target |
CD99_receptor |
3.219e-02 |
0.01 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
ITGB2_ligand |
B-cells(Good)_target |
ICAM1_receptor |
8.106e-05 |
0.0 |
ITGB2 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Poor)_source |
ITGB2_ligand |
B-cells(Good)_target |
ICAM1_receptor |
4.903e-06 |
0.01 |
ITGB2 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
ITGB2_ligand |
B-cells(Nos)_target |
ICAM1_receptor |
3.928e-04 |
0.01 |
ITGB2 |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Nos)_source |
ITGB2_ligand |
Monocytes(Nos)_target |
ICAM1_receptor |
3.486e-04 |
0.03 |
ITGB2 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
ITGB2_ligand |
Monocytes(Nos)_target |
ICAM1_receptor |
2.345e-04 |
0.0 |
ITGB2 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Poor)_source |
ITGB2_ligand |
Monocytes(Nos)_target |
ICAM1_receptor |
1.419e-05 |
0.01 |
ITGB2 |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Good)_source |
ITGB2_ligand |
B-cells(Good)_target |
ICAM2_receptor |
3.422e-05 |
0.0 |
ITGB2 |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Nos)_source |
ITGB2_ligand |
B-cells(Good)_target |
ICAM2_receptor |
3.291e-04 |
0.0 |
ITGB2 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
ITGB2_ligand |
B-cells(Good)_target |
ICAM2_receptor |
2.208e-04 |
0.0 |
ITGB2 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Poor)_source |
ITGB2_ligand |
B-cells(Good)_target |
ICAM2_receptor |
1.334e-05 |
0.0 |
ITGB2 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
ITGB2_ligand |
B-cells(Nos)_target |
ICAM2_receptor |
4.969e-04 |
0.0 |
ITGB2 |
Cell-Cell Contact |
KEGG: hsa04514 |