Sample overview
| Project Name |
TCGA-HNSC
|
| GSE ID |
GSE153559
|
| GSM ID |
GSM4647122
|
| Cell Line |
None
|
| Tissue type |
primary tumor
|
| Disease Type |
HPV+ HNSCC
|
| PMID |
33208941
|
| Initial gene number |
33538
|
| Initial cell number |
688
|
| Post-QC gene number |
879
|
| Post-QC cell number |
340
|
Bulk-to-ScRNA-seq Label Transfer
Bulk phenotype-associated subpopulations
Reference-Based Annotation
Differentially expressed genes
Overall Survival : Cluster
vs
There are no results of the analysis here
Overall Survival : Cluster
vs ( + )
There are no results of the analysis here
Clinical Stage : Cluster
vs
There
are no results of the analysis here
Tumor Size : Cluster
vs
There
are no results of the analysis here
Lymph Node Involvement : Cluster
vs
There
are no results of the analysis here
Distant Metastasis : Cluster
vs
There
are no results of the analysis here
Cell-Cell communications ( Survival-Associated Subpopulations Across Cell Types )
Cell Population Signaling and Communication
Ligand-Receptor-Mediated Cell-Cell Interactions
| Sending Cell Type |
Ligand |
Receiving Cell Type |
Receptor |
Score |
P-value |
Pathway Name |
Function |
Evidence |
| B-cells(Good)_source |
MIF_ligand |
B-cells(Good)_target |
CD74_CXCR4_receptor |
3.220e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| B-cells(Poor)_source |
MIF_ligand |
B-cells(Good)_target |
CD74_CXCR4_receptor |
1.933e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| Monocytes(Poor)_source |
MIF_ligand |
B-cells(Good)_target |
CD74_CXCR4_receptor |
1.770e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| B-cells(Good)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CXCR4_receptor |
3.806e-03 |
0.02 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| B-cells(Poor)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CXCR4_receptor |
2.287e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| Monocytes(Poor)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CXCR4_receptor |
2.094e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| B-cells(Poor)_source |
MIF_ligand |
B-cells(Poor)_target |
CD74_CXCR4_receptor |
9.034e-04 |
0.03 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| B-cells(Good)_source |
MIF_ligand |
Monocytes(Good)_target |
CD74_CXCR4_receptor |
2.549e-03 |
0.02 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| B-cells(Poor)_source |
MIF_ligand |
Monocytes(Good)_target |
CD74_CXCR4_receptor |
1.531e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| Monocytes(Poor)_source |
MIF_ligand |
Monocytes(Good)_target |
CD74_CXCR4_receptor |
1.402e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| B-cells(Poor)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CXCR4_receptor |
4.294e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| B-cells(Poor)_source |
MIF_ligand |
B-cells(Good)_target |
CD74_CD44_receptor |
1.803e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| B-cells(Poor)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CD44_receptor |
2.375e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Monocytes(Poor)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CD44_receptor |
2.175e-03 |
0.01 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| B-cells(Good)_source |
MIF_ligand |
Monocytes(Good)_target |
CD74_CD44_receptor |
2.849e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| B-cells(Poor)_source |
MIF_ligand |
Monocytes(Good)_target |
CD74_CD44_receptor |
1.707e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Monocytes(Good)_source |
MIF_ligand |
Monocytes(Good)_target |
CD74_CD44_receptor |
2.147e-03 |
0.04 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Monocytes(Poor)_source |
MIF_ligand |
Monocytes(Good)_target |
CD74_CD44_receptor |
1.564e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| B-cells(Good)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
8.579e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| B-cells(Poor)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
5.143e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Monocytes(Poor)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
4.713e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| B-cells(Poor)_source |
MIF_ligand |
Monocytes(Poor)_target |
CD74_CD44_receptor |
9.428e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Monocytes(Poor)_source |
MIF_ligand |
Monocytes(Poor)_target |
CD74_CD44_receptor |
8.632e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Monocytes(Good)_source |
ADGRE5_ligand |
Monocytes(Good)_target |
CD55_receptor |
1.918e-03 |
0.0 |
ADGRE5 |
Cell-Cell Contact |
PMID: 11297558 |
| Monocytes(Nos)_source |
ADGRE5_ligand |
Monocytes(Good)_target |
CD55_receptor |
6.058e-03 |
0.0 |
ADGRE5 |
Cell-Cell Contact |
PMID: 11297558 |
| Monocytes(Good)_source |
ADGRE5_ligand |
Monocytes(Nos)_target |
CD55_receptor |
5.629e-03 |
0.0 |
ADGRE5 |
Cell-Cell Contact |
PMID: 11297558 |
| Monocytes(Nos)_source |
ADGRE5_ligand |
Monocytes(Nos)_target |
CD55_receptor |
1.778e-02 |
0.0 |
ADGRE5 |
Cell-Cell Contact |
PMID: 11297558 |
| B-cells(Nos)_source |
CD99_ligand |
B-cells(Good)_target |
CD99_receptor |
7.565e-03 |
0.02 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Good)_source |
CD99_ligand |
B-cells(Good)_target |
CD99_receptor |
5.035e-03 |
0.01 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Good)_source |
CD99_ligand |
B-cells(Nos)_target |
CD99_receptor |
7.565e-03 |
0.02 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Nos)_source |
CD99_ligand |
B-cells(Nos)_target |
CD99_receptor |
9.672e-03 |
0.01 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Good)_source |
CD99_ligand |
B-cells(Nos)_target |
CD99_receptor |
6.437e-03 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Good)_source |
CD99_ligand |
Monocytes(Good)_target |
CD99_receptor |
5.035e-03 |
0.01 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Nos)_source |
CD99_ligand |
Monocytes(Good)_target |
CD99_receptor |
6.437e-03 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Good)_source |
CD99_ligand |
Monocytes(Good)_target |
CD99_receptor |
4.284e-03 |
0.02 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |