Sample overview
| Project Name |
TCGA-HNSC
|
| GSE ID |
GSE153559
|
| GSM ID |
GSM4647121
|
| Cell Line |
None
|
| Tissue type |
metastatic lymph node
|
| Disease Type |
HPV+ HNSCC
|
| PMID |
33208941
|
| Initial gene number |
33538
|
| Initial cell number |
1687
|
| Post-QC gene number |
5509
|
| Post-QC cell number |
1075
|
Bulk-to-ScRNA-seq Label Transfer
Bulk phenotype-associated subpopulations
Reference-Based Annotation
Differentially expressed genes
Overall Survival : Cluster
vs
There are no results of the analysis here
Overall Survival : Cluster
vs ( + )
There are no results of the analysis here
Clinical Stage : Cluster
vs
There
are no results of the analysis here
Tumor Size : Cluster
vs
There
are no results of the analysis here
Lymph Node Involvement : Cluster
vs
There
are no results of the analysis here
Distant Metastasis : Cluster
vs
There
are no results of the analysis here
Cell-Cell communications ( Survival-Associated Subpopulations Across Cell Types )
Cell Population Signaling and Communication
Ligand-Receptor-Mediated Cell-Cell Interactions
| Sending Cell Type |
Ligand |
Receiving Cell Type |
Receptor |
Score |
P-value |
Pathway Name |
Function |
Evidence |
| HSC(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CXCR4_receptor |
1.948e-02 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| HSC(Poor)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CXCR4_receptor |
4.493e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| HSC(Nos)_source |
MIF_ligand |
HSC(Nos)_target |
CD74_CXCR4_receptor |
1.096e-02 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| HSC(Poor)_source |
MIF_ligand |
HSC(Nos)_target |
CD74_CXCR4_receptor |
2.530e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| HSC(Poor)_source |
MIF_ligand |
HSC(Poor)_target |
CD74_CXCR4_receptor |
4.188e-04 |
0.01 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| B-cells(Good)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CD44_receptor |
3.948e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| B-cells(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CD44_receptor |
2.528e-02 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| HSC(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CD44_receptor |
1.745e-02 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| HSC(Poor)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CD44_receptor |
4.036e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| HSC(Poor)_source |
MIF_ligand |
HSC(Nos)_target |
CD74_CD44_receptor |
1.788e-03 |
0.01 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| B-cells(Nos)_source |
LGALS9_ligand |
B-cells(Nos)_target |
PTPRC_receptor |
2.169e-03 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| B-cells(Nos)_source |
LGALS9_ligand |
HSC(Nos)_target |
PTPRC_receptor |
1.381e-03 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| HSC(Poor)_source |
LGALS9_ligand |
HSC(Nos)_target |
PTPRC_receptor |
1.617e-04 |
0.04 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| B-cells(Nos)_source |
LGALS9_ligand |
HSC(Poor)_target |
PTPRC_receptor |
2.400e-04 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| B-cells(Nos)_source |
LGALS9_ligand |
B-cells(Nos)_target |
CD44_receptor |
1.296e-03 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| HSC(Nos)_source |
LGALS9_ligand |
B-cells(Nos)_target |
CD44_receptor |
5.865e-04 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| HSC(Poor)_source |
LGALS9_ligand |
B-cells(Nos)_target |
CD44_receptor |
1.517e-04 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| B-cells(Nos)_source |
ADGRE5_ligand |
B-cells(Nos)_target |
CD55_receptor |
1.015e-02 |
0.0 |
ADGRE5 |
Cell-Cell Contact |
PMID: 11297558 |
| B-cells(Nos)_source |
ADGRE5_ligand |
HSC(Nos)_target |
CD55_receptor |
5.014e-03 |
0.0 |
ADGRE5 |
Cell-Cell Contact |
PMID: 11297558 |
| HSC(Nos)_source |
CD22_ligand |
B-cells(Nos)_target |
PTPRC_receptor |
4.898e-03 |
0.0 |
CD22 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
CD22_ligand |
HSC(Nos)_target |
PTPRC_receptor |
3.113e-03 |
0.0 |
CD22 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
CD22_ligand |
HSC(Poor)_target |
PTPRC_receptor |
5.423e-04 |
0.0 |
CD22 |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Nos)_source |
PTPRC_ligand |
HSC(Nos)_target |
CD22_receptor |
4.898e-03 |
0.0 |
CD45 |
Cell-Cell Contact |
PMID: 12115612 |
| HSC(Nos)_source |
PTPRC_ligand |
HSC(Nos)_target |
CD22_receptor |
3.113e-03 |
0.0 |
CD45 |
Cell-Cell Contact |
PMID: 12115612 |
| HSC(Poor)_source |
PTPRC_ligand |
HSC(Nos)_target |
CD22_receptor |
5.423e-04 |
0.0 |
CD45 |
Cell-Cell Contact |
PMID: 12115612 |
| B-cells(Nos)_source |
CD99_ligand |
B-cells(Nos)_target |
CD99_receptor |
5.198e-02 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
CD99_ligand |
B-cells(Nos)_target |
CD99_receptor |
2.818e-02 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Nos)_source |
CD99_ligand |
HSC(Nos)_target |
CD99_receptor |
2.818e-02 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Good)_source |
ICAM2_ligand |
B-cells(Good)_target |
ITGAL_ITGB2_receptor |
3.845e-05 |
0.01 |
ICAM |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Good)_source |
ICAM2_ligand |
B-cells(Nos)_target |
ITGAL_ITGB2_receptor |
4.122e-04 |
0.0 |
ICAM |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Good)_source |
ICAM2_ligand |
HSC(Nos)_target |
ITGAL_ITGB2_receptor |
2.829e-04 |
0.0 |
ICAM |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Good)_source |
ICAM2_ligand |
HSC(Poor)_target |
ITGAL_ITGB2_receptor |
5.107e-05 |
0.0 |
ICAM |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Good)_source |
ITGB2_ligand |
B-cells(Good)_target |
ICAM2_receptor |
1.021e-04 |
0.0 |
ITGB2 |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Nos)_source |
ITGB2_ligand |
B-cells(Good)_target |
ICAM2_receptor |
7.133e-04 |
0.0 |
ITGB2 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
ITGB2_ligand |
B-cells(Good)_target |
ICAM2_receptor |
3.529e-04 |
0.0 |
ITGB2 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Poor)_source |
ITGB2_ligand |
B-cells(Good)_target |
ICAM2_receptor |
5.514e-05 |
0.0 |
ITGB2 |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Nos)_source |
HLA-F_ligand |
B-cells(Nos)_target |
LILRB1_receptor |
1.416e-03 |
0.0 |
MHC-I |
Cell-Cell Contact |
PMID: 28484462 |
| B-cells(Good)_source |
HLA-F_ligand |
HSC(Nos)_target |
LILRB1_receptor |
1.239e-04 |
0.02 |
MHC-I |
Cell-Cell Contact |
PMID: 28484462 |
| B-cells(Nos)_source |
HLA-F_ligand |
HSC(Nos)_target |
LILRB1_receptor |
1.260e-03 |
0.0 |
MHC-I |
Cell-Cell Contact |
PMID: 28484462 |
| HSC(Nos)_source |
HLA-F_ligand |
HSC(Nos)_target |
LILRB1_receptor |
4.623e-04 |
0.0 |
MHC-I |
Cell-Cell Contact |
PMID: 28484462 |
| B-cells(Good)_source |
MPZL1_ligand |
B-cells(Good)_target |
MPZL1_receptor |
1.414e-06 |
0.02 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
MPZL1_ligand |
B-cells(Good)_target |
MPZL1_receptor |
3.615e-06 |
0.01 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Poor)_source |
MPZL1_ligand |
B-cells(Good)_target |
MPZL1_receptor |
1.665e-06 |
0.0 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Good)_source |
MPZL1_ligand |
HSC(Nos)_target |
MPZL1_receptor |
3.615e-06 |
0.01 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Poor)_source |
MPZL1_ligand |
HSC(Nos)_target |
MPZL1_receptor |
4.257e-06 |
0.0 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Good)_source |
MPZL1_ligand |
HSC(Poor)_target |
MPZL1_receptor |
1.665e-06 |
0.0 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
MPZL1_ligand |
HSC(Poor)_target |
MPZL1_receptor |
4.257e-06 |
0.0 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Poor)_source |
MPZL1_ligand |
HSC(Poor)_target |
MPZL1_receptor |
1.961e-06 |
0.0 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |