Sample overview
| Project Name |
TCGA-HNSC
|
| GSE ID |
GSE153559
|
| GSM ID |
GSM4647118
|
| Cell Line |
None
|
| Tissue type |
primary tumor
|
| Disease Type |
HPV+ HNSCC
|
| PMID |
33208941
|
| Initial gene number |
33307
|
| Initial cell number |
2371
|
| Post-QC gene number |
4337
|
| Post-QC cell number |
2125
|
Bulk-to-ScRNA-seq Label Transfer
Bulk phenotype-associated subpopulations
Reference-Based Annotation
Differentially expressed genes
Overall Survival : Cluster
vs
There are no results of the analysis here
Overall Survival : Cluster
vs ( + )
There are no results of the analysis here
Clinical Stage : Cluster
vs
There
are no results of the analysis here
Tumor Size : Cluster
vs
There
are no results of the analysis here
Lymph Node Involvement : Cluster
vs
There
are no results of the analysis here
Distant Metastasis : Cluster
vs
There
are no results of the analysis here
Cell-Cell communications ( Survival-Associated Subpopulations Across Cell Types )
Cell Population Signaling and Communication
Ligand-Receptor-Mediated Cell-Cell Interactions
| Sending Cell Type |
Ligand |
Receiving Cell Type |
Receptor |
Score |
P-value |
Pathway Name |
Function |
Evidence |
| B-cells(Good)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CXCR4_receptor |
2.418e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| B-cells(Good)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CXCR4_receptor |
2.963e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| B-cells(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CXCR4_receptor |
2.392e-02 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| B-cells(Good)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CD44_receptor |
2.252e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| B-cells(Good)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
3.097e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| B-cells(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
2.503e-02 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Monocytes(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
2.844e-02 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Monocytes(Nos)_source |
TNF_ligand |
Monocytes(Nos)_target |
TNFRSF1B_receptor |
4.521e-04 |
0.0 |
TNF |
Secreted Signaling |
KEGG: hsa04060 |
| Monocytes(Nos)_source |
LGALS9_ligand |
B-cells(Good)_target |
PTPRC_receptor |
3.800e-05 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| Monocytes(Nos)_source |
LGALS9_ligand |
B-cells(Nos)_target |
PTPRC_receptor |
2.634e-03 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| Monocytes(Nos)_source |
LGALS9_ligand |
Monocytes(Nos)_target |
PTPRC_receptor |
4.097e-03 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| B-cells(Nos)_source |
BAG6_ligand |
Monocytes(Nos)_target |
NCR3_receptor |
2.304e-04 |
0.0 |
BAG |
Secreted Signaling |
PMID: 30021652 |
| Monocytes(Nos)_source |
BAG6_ligand |
Monocytes(Nos)_target |
NCR3_receptor |
3.009e-04 |
0.0 |
BAG |
Secreted Signaling |
PMID: 30021652 |
| Monocytes(Nos)_source |
LGALS9_ligand |
B-cells(Good)_target |
CD44_receptor |
8.044e-05 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| Monocytes(Nos)_source |
LGALS9_ligand |
B-cells(Nos)_target |
CD44_receptor |
2.123e-03 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| Monocytes(Nos)_source |
LGALS9_ligand |
Monocytes(Nos)_target |
CD44_receptor |
3.454e-03 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| Monocytes(Nos)_source |
ADGRE5_ligand |
B-cells(Nos)_target |
CD55_receptor |
3.216e-02 |
0.0 |
ADGRE5 |
Cell-Cell Contact |
PMID: 11297558 |
| Monocytes(Nos)_source |
ADGRE5_ligand |
Monocytes(Nos)_target |
CD55_receptor |
3.985e-02 |
0.0 |
ADGRE5 |
Cell-Cell Contact |
PMID: 11297558 |
| B-cells(Nos)_source |
CD22_ligand |
Monocytes(Nos)_target |
PTPRC_receptor |
2.279e-03 |
0.0 |
CD22 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
CD22_ligand |
Monocytes(Nos)_target |
PTPRC_receptor |
2.740e-03 |
0.0 |
CD22 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
PTPRC_ligand |
B-cells(Nos)_target |
CD22_receptor |
2.279e-03 |
0.0 |
CD45 |
Cell-Cell Contact |
PMID: 12115612 |
| Monocytes(Nos)_source |
PTPRC_ligand |
Monocytes(Nos)_target |
CD22_receptor |
2.740e-03 |
0.0 |
CD45 |
Cell-Cell Contact |
PMID: 12115612 |
| Monocytes(Nos)_source |
CD99_ligand |
Monocytes(Nos)_target |
CD99_receptor |
5.424e-02 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Good)_source |
ITGB2_ligand |
B-cells(Good)_target |
ICAM1_receptor |
6.157e-06 |
0.0 |
ITGB2 |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Nos)_source |
ITGB2_ligand |
B-cells(Good)_target |
ICAM1_receptor |
3.977e-05 |
0.0 |
ITGB2 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
ITGB2_ligand |
B-cells(Good)_target |
ICAM1_receptor |
6.503e-05 |
0.0 |
ITGB2 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
ITGB2_ligand |
Monocytes(Nos)_target |
ICAM1_receptor |
4.411e-04 |
0.03 |
ITGB2 |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Good)_source |
ITGB2_ligand |
B-cells(Good)_target |
ICAM2_receptor |
1.158e-05 |
0.0 |
ITGB2 |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Nos)_source |
ITGB2_ligand |
B-cells(Good)_target |
ICAM2_receptor |
7.490e-05 |
0.0 |
ITGB2 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
ITGB2_ligand |
B-cells(Good)_target |
ICAM2_receptor |
1.224e-04 |
0.0 |
ITGB2 |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Good)_source |
ITGB2_ligand |
B-cells(Nos)_target |
ICAM2_receptor |
3.521e-05 |
0.0 |
ITGB2 |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Nos)_source |
ITGB2_ligand |
B-cells(Nos)_target |
ICAM2_receptor |
2.273e-04 |
0.01 |
ITGB2 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
ITGB2_ligand |
B-cells(Nos)_target |
ICAM2_receptor |
3.718e-04 |
0.0 |
ITGB2 |
Cell-Cell Contact |
KEGG: hsa04514 |