Sample overview
| Project Name |
TCGA-HNSC
|
| GSE ID |
GSE139324
|
| GSM ID |
GSM4138158
|
| Cell Line |
None
|
| Tissue type |
peripheral blood
|
| Disease Type |
Head and neck squamous cell carcinoma
|
| PMID |
31924475
|
| Initial gene number |
33694
|
| Initial cell number |
1820
|
| Post-QC gene number |
1003
|
| Post-QC cell number |
1035
|
Bulk-to-ScRNA-seq Label Transfer
Bulk phenotype-associated subpopulations
Reference-Based Annotation
Differentially expressed genes
Overall Survival : Cluster
vs
There are no results of the analysis here
Overall Survival : Cluster
vs ( + )
There are no results of the analysis here
Clinical Stage : Cluster
vs
There
are no results of the analysis here
Tumor Size : Cluster
vs
There
are no results of the analysis here
Lymph Node Involvement : Cluster
vs
There
are no results of the analysis here
Distant Metastasis : Cluster
vs
There
are no results of the analysis here
Cell-Cell communications ( Survival-Associated Subpopulations Across Cell Types )
Cell Population Signaling and Communication
Ligand-Receptor-Mediated Cell-Cell Interactions
| Sending Cell Type |
Ligand |
Receiving Cell Type |
Receptor |
Score |
P-value |
Pathway Name |
Function |
Evidence |
| NK,cells(Nos)_source |
CD99_ligand |
NK,cells(Nos)_target |
CD99_receptor |
5.930e-02 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD4+,T-cells(Nos)_source |
CLEC2D_ligand |
NK,cells(Nos)_target |
KLRB1_receptor |
2.620e-03 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| CD8+,T-cells(Nos)_source |
CLEC2D_ligand |
NK,cells(Nos)_target |
KLRB1_receptor |
6.171e-04 |
0.01 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| NK,cells(Nos)_source |
CLEC2B_ligand |
CD4+,T-cells(Nos)_target |
KLRB1_receptor |
5.896e-03 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| NK,cells(Nos)_source |
CLEC2B_ligand |
CD8+,T-cells(Nos)_target |
KLRB1_receptor |
1.813e-03 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| NK,cells(Nos)_source |
CLEC2B_ligand |
NK,cells(Nos)_target |
KLRB1_receptor |
2.018e-02 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| CD4+,T-cells(Nos)_source |
CD69_ligand |
CD4+,T-cells(Nos)_target |
KLRB1_receptor |
3.618e-03 |
0.01 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| CD4+,T-cells(Nos)_source |
CD69_ligand |
CD8+,T-cells(Nos)_target |
KLRB1_receptor |
1.104e-03 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| CD8+,T-cells(Nos)_source |
CD69_ligand |
CD8+,T-cells(Nos)_target |
KLRB1_receptor |
1.997e-04 |
0.02 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| CD4+,T-cells(Nos)_source |
CD69_ligand |
NK,cells(Nos)_target |
KLRB1_receptor |
1.229e-02 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| CD8+,T-cells(Nos)_source |
CD69_ligand |
NK,cells(Nos)_target |
KLRB1_receptor |
2.224e-03 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| CD4+,T-cells(Nos)_source |
HLA-E_ligand |
NK,cells(Nos)_target |
KLRC1_receptor |
4.968e-02 |
0.0 |
MHC-I |
Cell-Cell Contact |
PMID: 24223577 |
| CD8+,T-cells(Nos)_source |
HLA-E_ligand |
NK,cells(Nos)_target |
KLRC1_receptor |
1.209e-02 |
0.0 |
MHC-I |
Cell-Cell Contact |
PMID: 24223577 |
| Monocytes(Nos)_source |
HLA-E_ligand |
NK,cells(Nos)_target |
KLRC1_receptor |
5.958e-03 |
0.0 |
MHC-I |
Cell-Cell Contact |
PMID: 24223577 |
| NK,cells(Nos)_source |
HLA-E_ligand |
NK,cells(Nos)_target |
KLRC1_receptor |
1.451e-01 |
0.0 |
MHC-I |
Cell-Cell Contact |
PMID: 24223577 |
| CD4+,T-cells(Nos)_source |
HLA-E_ligand |
NK,cells(Nos)_target |
CD94:NKG2A_receptor |
4.887e-02 |
0.0 |
MHC-I |
Cell-Cell Contact |
PMID: 28484462 |
| CD8+,T-cells(Nos)_source |
HLA-E_ligand |
NK,cells(Nos)_target |
CD94:NKG2A_receptor |
1.190e-02 |
0.0 |
MHC-I |
Cell-Cell Contact |
PMID: 28484462 |
| Monocytes(Nos)_source |
HLA-E_ligand |
NK,cells(Nos)_target |
CD94:NKG2A_receptor |
5.860e-03 |
0.0 |
MHC-I |
Cell-Cell Contact |
PMID: 28484462 |
| NK,cells(Nos)_source |
HLA-E_ligand |
NK,cells(Nos)_target |
CD94:NKG2A_receptor |
1.429e-01 |
0.0 |
MHC-I |
Cell-Cell Contact |
PMID: 28484462 |