Sample overview
| Project Name |
TCGA-HNSC
|
| GSE ID |
GSE139324
|
| GSM ID |
GSM4138151
|
| Cell Line |
None
|
| Tissue type |
tumor tissue
|
| Disease Type |
Head and neck squamous cell carcinoma
|
| PMID |
31924475
|
| Initial gene number |
33694
|
| Initial cell number |
2553
|
| Post-QC gene number |
2960
|
| Post-QC cell number |
2494
|
Bulk-to-ScRNA-seq Label Transfer
Bulk phenotype-associated subpopulations
Reference-Based Annotation
Differentially expressed genes
Overall Survival : Cluster
vs
There are no results of the analysis here
Overall Survival : Cluster
vs ( + )
There are no results of the analysis here
Clinical Stage : Cluster
vs
There
are no results of the analysis here
Tumor Size : Cluster
vs
There
are no results of the analysis here
Lymph Node Involvement : Cluster
vs
There
are no results of the analysis here
Distant Metastasis : Cluster
vs
There
are no results of the analysis here
Cell-Cell communications ( Survival-Associated Subpopulations Across Cell Types )
Cell Population Signaling and Communication
Ligand-Receptor-Mediated Cell-Cell Interactions
| Sending Cell Type |
Ligand |
Receiving Cell Type |
Receptor |
Score |
P-value |
Pathway Name |
Function |
Evidence |
| B-cells(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CXCR4_receptor |
2.795e-02 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| B-cells(Poor)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CXCR4_receptor |
6.682e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| B-cells(Poor)_source |
MIF_ligand |
CD8+,T-cells(Nos)_target |
CD74_CD44_receptor |
2.048e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| B-cells(Nos)_source |
CD22_ligand |
B-cells(Nos)_target |
PTPRC_receptor |
2.144e-02 |
0.0 |
CD22 |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Nos)_source |
CD22_ligand |
B-cells(Poor)_target |
PTPRC_receptor |
2.864e-04 |
0.0 |
CD22 |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Nos)_source |
CD22_ligand |
CD8+,T-cells(Nos)_target |
PTPRC_receptor |
1.782e-02 |
0.0 |
CD22 |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Poor)_source |
CD22_ligand |
CD8+,T-cells(Nos)_target |
PTPRC_receptor |
2.668e-04 |
0.01 |
CD22 |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Good)_source |
FCER2_ligand |
B-cells(Nos)_target |
CR2_receptor |
1.002e-08 |
0.0 |
CD23 |
Cell-Cell Contact |
PMID: 16785534 |
| B-cells(Nos)_source |
FCER2_ligand |
B-cells(Nos)_target |
CR2_receptor |
5.542e-04 |
0.0 |
CD23 |
Cell-Cell Contact |
PMID: 16785534 |
| B-cells(Poor)_source |
FCER2_ligand |
B-cells(Nos)_target |
CR2_receptor |
8.135e-09 |
0.0 |
CD23 |
Cell-Cell Contact |
PMID: 16785534 |
| CD8+,T-cells(Nos)_source |
FCER2_ligand |
B-cells(Nos)_target |
CR2_receptor |
7.389e-07 |
0.0 |
CD23 |
Cell-Cell Contact |
PMID: 16785534 |
| B-cells(Nos)_source |
FCER2_ligand |
B-cells(Poor)_target |
CR2_receptor |
5.254e-06 |
0.0 |
CD23 |
Cell-Cell Contact |
PMID: 16785534 |
| B-cells(Nos)_source |
FCER2_ligand |
CD8+,T-cells(Nos)_target |
CR2_receptor |
1.042e-07 |
0.0 |
CD23 |
Cell-Cell Contact |
PMID: 16785534 |
| CD8+,T-cells(Nos)_source |
FCER2_ligand |
CD8+,T-cells(Nos)_target |
CR2_receptor |
1.387e-10 |
0.0 |
CD23 |
Cell-Cell Contact |
PMID: 16785534 |
| B-cells(Nos)_source |
PTPRC_ligand |
B-cells(Nos)_target |
CD22_receptor |
2.144e-02 |
0.0 |
CD45 |
Cell-Cell Contact |
PMID: 12115612 |
| B-cells(Poor)_source |
PTPRC_ligand |
B-cells(Nos)_target |
CD22_receptor |
2.864e-04 |
0.0 |
CD45 |
Cell-Cell Contact |
PMID: 12115612 |
| CD8+,T-cells(Nos)_source |
PTPRC_ligand |
B-cells(Nos)_target |
CD22_receptor |
1.782e-02 |
0.0 |
CD45 |
Cell-Cell Contact |
PMID: 12115612 |
| CD8+,T-cells(Nos)_source |
PTPRC_ligand |
B-cells(Poor)_target |
CD22_receptor |
2.668e-04 |
0.01 |
CD45 |
Cell-Cell Contact |
PMID: 12115612 |
| CD8+,T-cells(Nos)_source |
CD99_ligand |
B-cells(Nos)_target |
CD99_receptor |
1.006e-02 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Nos)_source |
CD99_ligand |
CD8+,T-cells(Nos)_target |
CD99_receptor |
1.006e-02 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
CD99_ligand |
CD8+,T-cells(Nos)_target |
CD99_receptor |
8.271e-03 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Good)_source |
CLEC2D_ligand |
CD8+,T-cells(Nos)_target |
KLRB1_receptor |
9.057e-05 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| B-cells(Nos)_source |
CLEC2D_ligand |
CD8+,T-cells(Nos)_target |
KLRB1_receptor |
7.355e-03 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| B-cells(Poor)_source |
CLEC2D_ligand |
CD8+,T-cells(Nos)_target |
KLRB1_receptor |
1.326e-04 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| CD8+,T-cells(Nos)_source |
CLEC2D_ligand |
CD8+,T-cells(Nos)_target |
KLRB1_receptor |
4.687e-03 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| CD8+,T-cells(Nos)_source |
CLEC2B_ligand |
CD8+,T-cells(Nos)_target |
KLRB1_receptor |
1.475e-03 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| B-cells(Good)_source |
CD69_ligand |
CD8+,T-cells(Nos)_target |
KLRB1_receptor |
2.437e-05 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| B-cells(Nos)_source |
CD69_ligand |
CD8+,T-cells(Nos)_target |
KLRB1_receptor |
2.386e-03 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| B-cells(Poor)_source |
CD69_ligand |
CD8+,T-cells(Nos)_target |
KLRB1_receptor |
1.533e-05 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| CD8+,T-cells(Nos)_source |
CD69_ligand |
CD8+,T-cells(Nos)_target |
KLRB1_receptor |
4.963e-03 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| B-cells(Good)_source |
ICAM2_ligand |
B-cells(Nos)_target |
ITGAL_ITGB2_receptor |
1.408e-05 |
0.03 |
ICAM |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Good)_source |
ICAM2_ligand |
CD8+,T-cells(Nos)_target |
ITGAL_ITGB2_receptor |
2.363e-05 |
0.0 |
ICAM |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Nos)_source |
ITGB2_ligand |
B-cells(Good)_target |
ICAM2_receptor |
6.694e-05 |
0.0 |
ITGB2 |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
ITGB2_ligand |
B-cells(Good)_target |
ICAM2_receptor |
1.123e-04 |
0.0 |
ITGB2 |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
SEMA4D_ligand |
B-cells(Nos)_target |
CD72_receptor |
8.170e-07 |
0.0 |
SEMA4 |
Cell-Cell Contact |
PMID: 22325954 |