Sample overview
| Project Name |
TCGA-HNSC
|
| GSE ID |
GSE139324
|
| GSM ID |
GSM4138144
|
| Cell Line |
None
|
| Tissue type |
peripheral blood
|
| Disease Type |
Head and neck squamous cell carcinoma
|
| PMID |
31924475
|
| Initial gene number |
33694
|
| Initial cell number |
1783
|
| Post-QC gene number |
1170
|
| Post-QC cell number |
1187
|
Bulk-to-ScRNA-seq Label Transfer
Bulk phenotype-associated subpopulations
Reference-Based Annotation
Differentially expressed genes
Overall Survival : Cluster
vs
There are no results of the analysis here
Overall Survival : Cluster
vs ( + )
There are no results of the analysis here
Clinical Stage : Cluster
vs
There
are no results of the analysis here
Tumor Size : Cluster
vs
There
are no results of the analysis here
Lymph Node Involvement : Cluster
vs
There
are no results of the analysis here
Distant Metastasis : Cluster
vs
There
are no results of the analysis here
Cell-Cell communications ( Survival-Associated Subpopulations Across Cell Types )
Cell Population Signaling and Communication
Ligand-Receptor-Mediated Cell-Cell Interactions
| Sending Cell Type |
Ligand |
Receiving Cell Type |
Receptor |
Score |
P-value |
Pathway Name |
Function |
Evidence |
| B-cells(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CXCR4_receptor |
4.634e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| CD4+,T-cells(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CXCR4_receptor |
5.040e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| Monocytes(Good)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CXCR4_receptor |
2.707e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| Monocytes(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CXCR4_receptor |
3.039e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| NK,cells(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CXCR4_receptor |
1.332e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| B-cells(Nos)_source |
MIF_ligand |
Monocytes(Good)_target |
CD74_CXCR4_receptor |
2.106e-04 |
0.01 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| CD4+,T-cells(Nos)_source |
MIF_ligand |
Monocytes(Good)_target |
CD74_CXCR4_receptor |
2.296e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| Monocytes(Good)_source |
MIF_ligand |
Monocytes(Good)_target |
CD74_CXCR4_receptor |
1.232e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| NK,cells(Nos)_source |
MIF_ligand |
Monocytes(Good)_target |
CD74_CXCR4_receptor |
6.085e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| CD4+,T-cells(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CXCR4_receptor |
3.158e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| Monocytes(Good)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CXCR4_receptor |
1.693e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| NK,cells(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CXCR4_receptor |
8.377e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| NK,cells(Nos)_source |
MIF_ligand |
NK,cells(Nos)_target |
CD74_CXCR4_receptor |
1.561e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| B-cells(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CD44_receptor |
2.767e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| CD4+,T-cells(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CD44_receptor |
3.035e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Monocytes(Good)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CD44_receptor |
1.623e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| NK,cells(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CD44_receptor |
8.093e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| B-cells(Nos)_source |
MIF_ligand |
Monocytes(Good)_target |
CD74_CD44_receptor |
1.677e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| CD4+,T-cells(Nos)_source |
MIF_ligand |
Monocytes(Good)_target |
CD74_CD44_receptor |
1.836e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Monocytes(Good)_source |
MIF_ligand |
Monocytes(Good)_target |
CD74_CD44_receptor |
9.825e-05 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Monocytes(Nos)_source |
MIF_ligand |
Monocytes(Good)_target |
CD74_CD44_receptor |
1.096e-04 |
0.02 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| NK,cells(Nos)_source |
MIF_ligand |
Monocytes(Good)_target |
CD74_CD44_receptor |
4.883e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| B-cells(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
2.540e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| CD4+,T-cells(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
2.779e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Monocytes(Good)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
1.488e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Monocytes(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
1.660e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| NK,cells(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
7.389e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Monocytes(Good)_source |
ADGRE5_ligand |
B-cells(Nos)_target |
CD55_receptor |
9.876e-06 |
0.04 |
ADGRE5 |
Cell-Cell Contact |
PMID: 11297558 |
| Monocytes(Nos)_source |
ADGRE5_ligand |
B-cells(Nos)_target |
CD55_receptor |
5.377e-05 |
0.0 |
ADGRE5 |
Cell-Cell Contact |
PMID: 11297558 |
| NK,cells(Nos)_source |
ADGRE5_ligand |
B-cells(Nos)_target |
CD55_receptor |
5.647e-05 |
0.0 |
ADGRE5 |
Cell-Cell Contact |
PMID: 11297558 |
| Monocytes(Nos)_source |
ADGRE5_ligand |
Monocytes(Good)_target |
CD55_receptor |
2.701e-05 |
0.0 |
ADGRE5 |
Cell-Cell Contact |
PMID: 11297558 |
| NK,cells(Nos)_source |
ADGRE5_ligand |
Monocytes(Good)_target |
CD55_receptor |
2.836e-05 |
0.0 |
ADGRE5 |
Cell-Cell Contact |
PMID: 11297558 |
| Monocytes(Good)_source |
ADGRE5_ligand |
Monocytes(Nos)_target |
CD55_receptor |
1.859e-05 |
0.0 |
ADGRE5 |
Cell-Cell Contact |
PMID: 11297558 |
| Monocytes(Nos)_source |
ADGRE5_ligand |
Monocytes(Nos)_target |
CD55_receptor |
9.995e-05 |
0.0 |
ADGRE5 |
Cell-Cell Contact |
PMID: 11297558 |
| NK,cells(Nos)_source |
ADGRE5_ligand |
Monocytes(Nos)_target |
CD55_receptor |
1.060e-04 |
0.0 |
ADGRE5 |
Cell-Cell Contact |
PMID: 11297558 |
| NK,cells(Nos)_source |
CD99_ligand |
CD4+,T-cells(Nos)_target |
CD99_receptor |
1.269e-02 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| NK,cells(Nos)_source |
CD99_ligand |
Monocytes(Good)_target |
CD99_receptor |
7.537e-04 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| NK,cells(Nos)_source |
CD99_ligand |
Monocytes(Nos)_target |
CD99_receptor |
1.034e-03 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD4+,T-cells(Nos)_source |
CD99_ligand |
NK,cells(Nos)_target |
CD99_receptor |
1.269e-02 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Good)_source |
CD99_ligand |
NK,cells(Nos)_target |
CD99_receptor |
7.537e-04 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
CD99_ligand |
NK,cells(Nos)_target |
CD99_receptor |
1.034e-03 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| NK,cells(Nos)_source |
CD99_ligand |
NK,cells(Nos)_target |
CD99_receptor |
5.234e-03 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Nos)_source |
CLEC2D_ligand |
NK,cells(Nos)_target |
KLRB1_receptor |
7.687e-04 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| CD4+,T-cells(Nos)_source |
CLEC2D_ligand |
NK,cells(Nos)_target |
KLRB1_receptor |
6.285e-03 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| Monocytes(Nos)_source |
CLEC2B_ligand |
CD4+,T-cells(Nos)_target |
KLRB1_receptor |
4.685e-04 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| Monocytes(Good)_source |
CLEC2B_ligand |
NK,cells(Nos)_target |
KLRB1_receptor |
2.506e-04 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| Monocytes(Nos)_source |
CLEC2B_ligand |
NK,cells(Nos)_target |
KLRB1_receptor |
9.366e-04 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| NK,cells(Nos)_source |
CLEC2B_ligand |
NK,cells(Nos)_target |
KLRB1_receptor |
1.740e-03 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| B-cells(Nos)_source |
CD69_ligand |
NK,cells(Nos)_target |
KLRB1_receptor |
3.246e-03 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| CD4+,T-cells(Nos)_source |
CD69_ligand |
NK,cells(Nos)_target |
KLRB1_receptor |
1.891e-02 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| NK,cells(Nos)_source |
CD69_ligand |
NK,cells(Nos)_target |
KLRB1_receptor |
4.101e-03 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |