Sample overview
| Project Name |
TCGA-HNSC
|
| GSE ID |
GSE139324
|
| GSM ID |
GSM4138142
|
| Cell Line |
None
|
| Tissue type |
peripheral blood
|
| Disease Type |
Head and neck squamous cell carcinoma
|
| PMID |
31924475
|
| Initial gene number |
33694
|
| Initial cell number |
1806
|
| Post-QC gene number |
1303
|
| Post-QC cell number |
805
|
Bulk-to-ScRNA-seq Label Transfer
Bulk phenotype-associated subpopulations
Reference-Based Annotation
Differentially expressed genes
Overall Survival : Cluster
vs
There are no results of the analysis here
Overall Survival : Cluster
vs ( + )
There are no results of the analysis here
Clinical Stage : Cluster
vs
There
are no results of the analysis here
Tumor Size : Cluster
vs
There
are no results of the analysis here
Lymph Node Involvement : Cluster
vs
There
are no results of the analysis here
Distant Metastasis : Cluster
vs
There
are no results of the analysis here
Cell-Cell communications ( Survival-Associated Subpopulations Across Cell Types )
Cell Population Signaling and Communication
Ligand-Receptor-Mediated Cell-Cell Interactions
| Sending Cell Type |
Ligand |
Receiving Cell Type |
Receptor |
Score |
P-value |
Pathway Name |
Function |
Evidence |
| B-cells(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CXCR4_receptor |
4.149e-05 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| CD4+,T-cells(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CXCR4_receptor |
8.510e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| Monocytes(Good)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CXCR4_receptor |
1.377e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| Monocytes(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CXCR4_receptor |
3.335e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| NK,cells(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CXCR4_receptor |
5.916e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| CD4+,T-cells(Nos)_source |
MIF_ligand |
CD4+,T-cells(Nos)_target |
CD74_CXCR4_receptor |
6.737e-03 |
0.01 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| CD4+,T-cells(Nos)_source |
MIF_ligand |
NK,cells(Nos)_target |
CD74_CXCR4_receptor |
4.836e-03 |
0.03 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| B-cells(Nos)_source |
MIF_ligand |
Monocytes(Good)_target |
CD74_CD44_receptor |
1.105e-04 |
0.02 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| CD4+,T-cells(Nos)_source |
MIF_ligand |
Monocytes(Good)_target |
CD74_CD44_receptor |
2.285e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| NK,cells(Nos)_source |
MIF_ligand |
Monocytes(Good)_target |
CD74_CD44_receptor |
1.582e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| B-cells(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
3.120e-04 |
0.01 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| CD4+,T-cells(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
6.441e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Monocytes(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
2.499e-03 |
0.02 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| NK,cells(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
4.463e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Monocytes(Good)_source |
LGALS9_ligand |
CD4+,T-cells(Nos)_target |
CD44_receptor |
1.299e-03 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| Monocytes(Nos)_source |
LGALS9_ligand |
CD4+,T-cells(Nos)_target |
CD44_receptor |
3.757e-03 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| Monocytes(Good)_source |
LGALS9_ligand |
Monocytes(Good)_target |
CD44_receptor |
4.748e-04 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| Monocytes(Nos)_source |
LGALS9_ligand |
Monocytes(Good)_target |
CD44_receptor |
1.370e-03 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| Monocytes(Good)_source |
LGALS9_ligand |
Monocytes(Nos)_target |
CD44_receptor |
1.213e-03 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| Monocytes(Nos)_source |
LGALS9_ligand |
Monocytes(Nos)_target |
CD44_receptor |
3.503e-03 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| Monocytes(Nos)_source |
LGALS9_ligand |
NK,cells(Nos)_target |
CD44_receptor |
1.006e-03 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| CD4+,T-cells(Nos)_source |
ADGRE5_ligand |
Monocytes(Good)_target |
CD55_receptor |
2.390e-04 |
0.0 |
ADGRE5 |
Cell-Cell Contact |
PMID: 11297558 |
| Monocytes(Nos)_source |
ADGRE5_ligand |
Monocytes(Good)_target |
CD55_receptor |
4.497e-04 |
0.0 |
ADGRE5 |
Cell-Cell Contact |
PMID: 11297558 |
| NK,cells(Nos)_source |
ADGRE5_ligand |
Monocytes(Good)_target |
CD55_receptor |
2.835e-04 |
0.0 |
ADGRE5 |
Cell-Cell Contact |
PMID: 11297558 |
| Monocytes(Nos)_source |
ADGRE5_ligand |
Monocytes(Nos)_target |
CD55_receptor |
7.048e-04 |
0.0 |
ADGRE5 |
Cell-Cell Contact |
PMID: 11297558 |
| NK,cells(Nos)_source |
ADGRE5_ligand |
Monocytes(Nos)_target |
CD55_receptor |
4.425e-04 |
0.0 |
ADGRE5 |
Cell-Cell Contact |
PMID: 11297558 |
| NK,cells(Nos)_source |
CD99_ligand |
CD4+,T-cells(Nos)_target |
CD99_receptor |
1.447e-02 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| NK,cells(Nos)_source |
CD99_ligand |
Monocytes(Good)_target |
CD99_receptor |
3.519e-03 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| NK,cells(Nos)_source |
CD99_ligand |
Monocytes(Nos)_target |
CD99_receptor |
7.762e-03 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD4+,T-cells(Nos)_source |
CD99_ligand |
NK,cells(Nos)_target |
CD99_receptor |
1.447e-02 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Good)_source |
CD99_ligand |
NK,cells(Nos)_target |
CD99_receptor |
3.519e-03 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
CD99_ligand |
NK,cells(Nos)_target |
CD99_receptor |
7.762e-03 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| NK,cells(Nos)_source |
CD99_ligand |
NK,cells(Nos)_target |
CD99_receptor |
2.189e-02 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD4+,T-cells(Nos)_source |
CLEC2B_ligand |
NK,cells(Nos)_target |
KLRB1_receptor |
6.312e-03 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| Monocytes(Good)_source |
CLEC2B_ligand |
NK,cells(Nos)_target |
KLRB1_receptor |
8.940e-04 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| Monocytes(Nos)_source |
CLEC2B_ligand |
NK,cells(Nos)_target |
KLRB1_receptor |
3.680e-03 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| NK,cells(Nos)_source |
CLEC2B_ligand |
NK,cells(Nos)_target |
KLRB1_receptor |
6.741e-03 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| B-cells(Nos)_source |
CD69_ligand |
NK,cells(Nos)_target |
KLRB1_receptor |
1.428e-03 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| CD4+,T-cells(Nos)_source |
CD69_ligand |
NK,cells(Nos)_target |
KLRB1_receptor |
2.876e-02 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| NK,cells(Nos)_source |
CD69_ligand |
NK,cells(Nos)_target |
KLRB1_receptor |
6.693e-03 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |