Sample overview
| Project Name |
TCGA-HNSC
|
| GSE ID |
GSE139324
|
| GSM ID |
GSM4138138
|
| Cell Line |
None
|
| Tissue type |
peripheral blood
|
| Disease Type |
Head and neck squamous cell carcinoma
|
| PMID |
31924475
|
| Initial gene number |
33694
|
| Initial cell number |
2062
|
| Post-QC gene number |
995
|
| Post-QC cell number |
1058
|
Bulk-to-ScRNA-seq Label Transfer
Bulk phenotype-associated subpopulations
Reference-Based Annotation
Differentially expressed genes
Overall Survival : Cluster
vs
There are no results of the analysis here
Overall Survival : Cluster
vs ( + )
There are no results of the analysis here
Clinical Stage : Cluster
vs
There
are no results of the analysis here
Tumor Size : Cluster
vs
There
are no results of the analysis here
Lymph Node Involvement : Cluster
vs
There
are no results of the analysis here
Distant Metastasis : Cluster
vs
There
are no results of the analysis here
Cell-Cell communications ( Survival-Associated Subpopulations Across Cell Types )
Cell Population Signaling and Communication
Ligand-Receptor-Mediated Cell-Cell Interactions
| Sending Cell Type |
Ligand |
Receiving Cell Type |
Receptor |
Score |
P-value |
Pathway Name |
Function |
Evidence |
| CD4+,T-cells(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CXCR4_receptor |
9.815e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| CD8+,T-cells(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CXCR4_receptor |
2.659e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| NK,cells(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CXCR4_receptor |
2.384e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| CD4+,T-cells(Nos)_source |
MIF_ligand |
CD8+,T-cells(Nos)_target |
CD74_CXCR4_receptor |
6.065e-04 |
0.02 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| CD8+,T-cells(Nos)_source |
MIF_ligand |
CD8+,T-cells(Nos)_target |
CD74_CXCR4_receptor |
1.687e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| CD4+,T-cells(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CXCR4_receptor |
9.917e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| CD8+,T-cells(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CXCR4_receptor |
2.752e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| CD4+,T-cells(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CD44_receptor |
4.100e-04 |
0.02 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| CD8+,T-cells(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CD44_receptor |
1.149e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| CD8+,T-cells(Nos)_source |
MIF_ligand |
CD4+,T-cells(Nos)_target |
CD74_CD44_receptor |
1.101e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| CD4+,T-cells(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
9.789e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| CD8+,T-cells(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
2.717e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| NK,cells(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
2.386e-04 |
0.04 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| NK,cells(Nos)_source |
CD99_ligand |
B-cells(Nos)_target |
CD99_receptor |
3.933e-04 |
0.03 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| NK,cells(Nos)_source |
CD99_ligand |
CD4+,T-cells(Nos)_target |
CD99_receptor |
4.650e-03 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
CD99_ligand |
CD8+,T-cells(Nos)_target |
CD99_receptor |
3.494e-04 |
0.02 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| NK,cells(Nos)_source |
CD99_ligand |
CD8+,T-cells(Nos)_target |
CD99_receptor |
1.212e-03 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Nos)_source |
CD99_ligand |
NK,cells(Nos)_target |
CD99_receptor |
3.933e-04 |
0.03 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD4+,T-cells(Nos)_source |
CD99_ligand |
NK,cells(Nos)_target |
CD99_receptor |
4.650e-03 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
CD99_ligand |
NK,cells(Nos)_target |
CD99_receptor |
1.212e-03 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| NK,cells(Nos)_source |
CD99_ligand |
NK,cells(Nos)_target |
CD99_receptor |
4.024e-03 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
CLEC2B_ligand |
NK,cells(Nos)_target |
KLRB1_receptor |
6.583e-04 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| NK,cells(Nos)_source |
CLEC2B_ligand |
NK,cells(Nos)_target |
KLRB1_receptor |
1.552e-03 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| B-cells(Nos)_source |
CD69_ligand |
NK,cells(Nos)_target |
KLRB1_receptor |
1.653e-03 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| CD4+,T-cells(Nos)_source |
CD69_ligand |
NK,cells(Nos)_target |
KLRB1_receptor |
2.001e-02 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| CD8+,T-cells(Nos)_source |
CD69_ligand |
NK,cells(Nos)_target |
KLRB1_receptor |
2.335e-03 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| NK,cells(Nos)_source |
CD69_ligand |
NK,cells(Nos)_target |
KLRB1_receptor |
1.657e-03 |
0.0 |
CLEC |
Cell-Cell Contact |
PMID: 24223577 |
| Monocytes(Nos)_source |
SELPLG_ligand |
B-cells(Nos)_target |
SELL_receptor |
3.291e-05 |
0.0 |
SELPLG |
Cell-Cell Contact |
PMC2431087; PMID: 8892633,PMID: 8896607 |
| Monocytes(Nos)_source |
SELPLG_ligand |
CD4+,T-cells(Nos)_target |
SELL_receptor |
8.891e-04 |
0.0 |
SELPLG |
Cell-Cell Contact |
PMC2431087; PMID: 8892633,PMID: 8896607 |
| Monocytes(Nos)_source |
SELPLG_ligand |
Monocytes(Nos)_target |
SELL_receptor |
3.965e-05 |
0.03 |
SELPLG |
Cell-Cell Contact |
PMC2431087; PMID: 8892633,PMID: 8896607 |