Sample overview
| Project Name |
TCGA-HNSC
|
| GSE ID |
GSE139324
|
| GSM ID |
GSM4138129
|
| Cell Line |
None
|
| Tissue type |
tumor tissue
|
| Disease Type |
Head and neck squamous cell carcinoma
|
| PMID |
31924475
|
| Initial gene number |
33694
|
| Initial cell number |
1384
|
| Post-QC gene number |
985
|
| Post-QC cell number |
901
|
Bulk-to-ScRNA-seq Label Transfer
Bulk phenotype-associated subpopulations
Reference-Based Annotation
Differentially expressed genes
Overall Survival : Cluster
vs
There are no results of the analysis here
Overall Survival : Cluster
vs ( + )
There are no results of the analysis here
Clinical Stage : Cluster
vs
There
are no results of the analysis here
Tumor Size : Cluster
vs
There
are no results of the analysis here
Lymph Node Involvement : Cluster
vs
There
are no results of the analysis here
Distant Metastasis : Cluster
vs
There
are no results of the analysis here
Cell-Cell communications ( Survival-Associated Subpopulations Across Cell Types )
Cell Population Signaling and Communication
Ligand-Receptor-Mediated Cell-Cell Interactions
| Sending Cell Type |
Ligand |
Receiving Cell Type |
Receptor |
Score |
P-value |
Pathway Name |
Function |
Evidence |
| B-cells(Nos)_source |
MIF_ligand |
CD8+,T-cells(Nos)_target |
CD74_CXCR4_receptor |
1.838e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| CD4+,T-cells(Nos)_source |
MIF_ligand |
CD8+,T-cells(Nos)_target |
CD74_CXCR4_receptor |
3.280e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| CD8+,T-cells(Nos)_source |
MIF_ligand |
CD8+,T-cells(Nos)_target |
CD74_CXCR4_receptor |
2.477e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| B-cells(Nos)_source |
MIF_ligand |
CD8+,T-cells(Nos)_target |
CD74_CD44_receptor |
1.729e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| CD4+,T-cells(Nos)_source |
MIF_ligand |
CD8+,T-cells(Nos)_target |
CD74_CD44_receptor |
3.085e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| CD8+,T-cells(Nos)_source |
MIF_ligand |
CD8+,T-cells(Nos)_target |
CD74_CD44_receptor |
2.329e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| B-cells(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
5.019e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| CD4+,T-cells(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
8.954e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| CD8+,T-cells(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
6.765e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Monocytes(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
1.223e-04 |
0.02 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| B-cells(Nos)_source |
SPP1_ligand |
B-cells(Nos)_target |
CD44_receptor |
4.136e-04 |
0.0 |
SPP1 |
Secreted Signaling |
PMID: 21907263 |
| Monocytes(Nos)_source |
SPP1_ligand |
B-cells(Nos)_target |
CD44_receptor |
1.469e-04 |
0.01 |
SPP1 |
Secreted Signaling |
PMID: 21907263 |
| B-cells(Nos)_source |
SPP1_ligand |
CD4+,T-cells(Nos)_target |
CD44_receptor |
1.255e-03 |
0.0 |
SPP1 |
Secreted Signaling |
PMID: 21907263 |
| Monocytes(Nos)_source |
SPP1_ligand |
CD4+,T-cells(Nos)_target |
CD44_receptor |
4.450e-04 |
0.0 |
SPP1 |
Secreted Signaling |
PMID: 21907263 |
| B-cells(Nos)_source |
SPP1_ligand |
CD8+,T-cells(Nos)_target |
CD44_receptor |
1.254e-03 |
0.0 |
SPP1 |
Secreted Signaling |
PMID: 21907263 |
| CD4+,T-cells(Nos)_source |
SPP1_ligand |
CD8+,T-cells(Nos)_target |
CD44_receptor |
1.077e-03 |
0.0 |
SPP1 |
Secreted Signaling |
PMID: 21907263 |
| Monocytes(Nos)_source |
SPP1_ligand |
CD8+,T-cells(Nos)_target |
CD44_receptor |
4.443e-04 |
0.0 |
SPP1 |
Secreted Signaling |
PMID: 21907263 |
| B-cells(Nos)_source |
SPP1_ligand |
Monocytes(Nos)_target |
CD44_receptor |
3.455e-04 |
0.0 |
SPP1 |
Secreted Signaling |
PMID: 21907263 |
| CD4+,T-cells(Nos)_source |
SPP1_ligand |
Monocytes(Nos)_target |
CD44_receptor |
2.977e-04 |
0.0 |
SPP1 |
Secreted Signaling |
PMID: 21907263 |
| Monocytes(Nos)_source |
SPP1_ligand |
Monocytes(Nos)_target |
CD44_receptor |
1.222e-04 |
0.0 |
SPP1 |
Secreted Signaling |
PMID: 21907263 |
| CD8+,T-cells(Nos)_source |
CD99_ligand |
CD4+,T-cells(Nos)_target |
CD99_receptor |
7.988e-03 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD4+,T-cells(Nos)_source |
CD99_ligand |
CD8+,T-cells(Nos)_target |
CD99_receptor |
7.988e-03 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
CD99_ligand |
CD8+,T-cells(Nos)_target |
CD99_receptor |
9.716e-03 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
CD99_ligand |
CD8+,T-cells(Nos)_target |
CD99_receptor |
1.123e-03 |
0.03 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
CD99_ligand |
Monocytes(Nos)_target |
CD99_receptor |
1.123e-03 |
0.03 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |