Sample overview
| Project Name | TCGA-COAD |
| GSE ID | GSE201348 |
| GSM ID | GSM6061693 |
| Cell Line | None |
| Tissue type | Colon |
| Disease Type | Polyp |
| PMID | 35726067 |
| Initial gene number | 33538 |
| Initial cell number | 3729 |
| Post-QC gene number | 3138 |
| Post-QC cell number | 3700 |
QC Metrics
Bulk-to-ScRNA-seq Label Transfer
Bulk phenotype-associated subpopulations
Reference-Based Annotation
Differentially expressed genes
Overall Survival : Cluster vs
There are no results of the analysis here
Overall Survival : Cluster vs ( + )
There are no results of the analysis here
Clinical Stage : Cluster vs
There are no results of the analysis here
Tumor Size : Cluster vs
There are no results of the analysis here
Lymph Node Involvement : Cluster vs
There are no results of the analysis here
Distant Metastasis : Cluster vs
There are no results of the analysis here
Cell-Cell communications ( Survival-Associated Subpopulations Across Cell Types )
Cell Population Signaling and Communication
Ligand-Receptor-Mediated Cell-Cell Interactions
| Sending Cell Type | Ligand | Receiving Cell Type | Receptor | Score | P-value | Pathway Name | Function | Evidence |
|---|---|---|---|---|---|---|---|---|
| Neurons(Nos)_source | PRSS3_ligand | Neurons(Good)_target | PARD3_receptor | 5.442e-04 | 0.02 | PARs | Secreted Signaling | KEGG: hsa04080 |
| Skeletal,muscle(Good)_source | PRSS3_ligand | Neurons(Good)_target | PARD3_receptor | 3.952e-05 | 0.0 | PARs | Secreted Signaling | KEGG: hsa04080 |
| Skeletal,muscle(Nos)_source | PRSS3_ligand | Neurons(Good)_target | PARD3_receptor | 4.374e-04 | 0.0 | PARs | Secreted Signaling | KEGG: hsa04080 |
| Neurons(Good)_source | PRSS3_ligand | Neurons(Nos)_target | PARD3_receptor | 5.741e-04 | 0.02 | PARs | Secreted Signaling | KEGG: hsa04080 |
| Neurons(Nos)_source | PRSS3_ligand | Neurons(Nos)_target | PARD3_receptor | 8.673e-03 | 0.0 | PARs | Secreted Signaling | KEGG: hsa04080 |
| Skeletal,muscle(Good)_source | PRSS3_ligand | Neurons(Nos)_target | PARD3_receptor | 6.299e-04 | 0.0 | PARs | Secreted Signaling | KEGG: hsa04080 |
| Skeletal,muscle(Nos)_source | PRSS3_ligand | Neurons(Nos)_target | PARD3_receptor | 6.972e-03 | 0.0 | PARs | Secreted Signaling | KEGG: hsa04080 |
| Neurons(Good)_source | PRSS3_ligand | Skeletal,muscle(Good)_target | PARD3_receptor | 2.803e-05 | 0.04 | PARs | Secreted Signaling | KEGG: hsa04080 |
| Neurons(Nos)_source | PRSS3_ligand | Skeletal,muscle(Good)_target | PARD3_receptor | 4.235e-04 | 0.0 | PARs | Secreted Signaling | KEGG: hsa04080 |
| Skeletal,muscle(Good)_source | PRSS3_ligand | Skeletal,muscle(Good)_target | PARD3_receptor | 3.074e-05 | 0.0 | PARs | Secreted Signaling | KEGG: hsa04080 |
| Skeletal,muscle(Nos)_source | PRSS3_ligand | Skeletal,muscle(Good)_target | PARD3_receptor | 3.404e-04 | 0.0 | PARs | Secreted Signaling | KEGG: hsa04080 |
| Skeletal,muscle(Good)_source | PRSS3_ligand | Skeletal,muscle(Nos)_target | PARD3_receptor | 3.990e-04 | 0.0 | PARs | Secreted Signaling | KEGG: hsa04080 |
| Skeletal,muscle(Nos)_source | PRSS3_ligand | Skeletal,muscle(Nos)_target | PARD3_receptor | 4.402e-03 | 0.04 | PARs | Secreted Signaling | KEGG: hsa04080 |
| Skeletal,muscle(Good)_source | LGALS9_ligand | Neurons(Good)_target | CD44_receptor | 2.419e-06 | 0.01 | GALECTIN | Secreted Signaling | PMID: 25065622 |
| Skeletal,muscle(Good)_source | LGALS9_ligand | Neurons(Nos)_target | CD44_receptor | 4.616e-05 | 0.04 | GALECTIN | Secreted Signaling | PMID: 25065622 |
| Skeletal,muscle(Good)_source | LGALS9_ligand | Skeletal,muscle(Good)_target | CD44_receptor | 1.912e-06 | 0.03 | GALECTIN | Secreted Signaling | PMID: 25065622 |
| Skeletal,muscle(Good)_source | LAMA3_ligand | B-cells(Nos)_target | ITGA2_ITGB1_receptor | 3.089e-08 | 0.04 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Skeletal,muscle(Good)_source | LAMA3_ligand | Chondrocytes(Nos)_target | ITGA2_ITGB1_receptor | 2.760e-07 | 0.04 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Skeletal,muscle(Good)_source | LAMA3_ligand | Neurons(Good)_target | ITGA2_ITGB1_receptor | 1.625e-06 | 0.01 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Skeletal,muscle(Good)_source | LAMA3_ligand | Neurons(Nos)_target | ITGA2_ITGB1_receptor | 2.850e-05 | 0.02 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Skeletal,muscle(Good)_source | LAMA3_ligand | Neutrophils(Nos)_target | ITGA2_ITGB1_receptor | 1.260e-07 | 0.04 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Skeletal,muscle(Good)_source | LAMA3_ligand | Skeletal,muscle(Good)_target | ITGA2_ITGB1_receptor | 3.958e-06 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Skeletal,muscle(Good)_source | LAMA3_ligand | Skeletal,muscle(Nos)_target | ITGA2_ITGB1_receptor | 1.732e-05 | 0.02 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Chondrocytes(Nos)_source | LAMB1_ligand | B-cells(Nos)_target | ITGA2_ITGB1_receptor | 3.151e-07 | 0.01 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Chondrocytes(Nos)_source | LAMB1_ligand | Chondrocytes(Nos)_target | ITGA2_ITGB1_receptor | 2.810e-06 | 0.01 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Chondrocytes(Nos)_source | LAMB1_ligand | Neurons(Good)_target | ITGA2_ITGB1_receptor | 1.636e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Chondrocytes(Nos)_source | LAMB1_ligand | Neurons(Nos)_target | ITGA2_ITGB1_receptor | 2.865e-04 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Chondrocytes(Nos)_source | LAMB1_ligand | Neutrophils(Nos)_target | ITGA2_ITGB1_receptor | 1.283e-06 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Chondrocytes(Nos)_source | LAMB1_ligand | Skeletal,muscle(Good)_target | ITGA2_ITGB1_receptor | 3.873e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Chondrocytes(Nos)_source | LAMB1_ligand | Skeletal,muscle(Nos)_target | ITGA2_ITGB1_receptor | 1.746e-04 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Skeletal,muscle(Good)_source | LAMA3_ligand | Skeletal,muscle(Good)_target | ITGA3_ITGB1_receptor | 2.480e-06 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Chondrocytes(Nos)_source | LAMB1_ligand | Skeletal,muscle(Good)_target | ITGA3_ITGB1_receptor | 2.464e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Skeletal,muscle(Good)_source | LAMA3_ligand | B-cells(Nos)_target | ITGA6_ITGB1_receptor | 2.241e-08 | 0.04 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Skeletal,muscle(Good)_source | LAMA3_ligand | Chondrocytes(Nos)_target | ITGA6_ITGB1_receptor | 9.531e-07 | 0.04 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Skeletal,muscle(Good)_source | LAMA3_ligand | Neurons(Good)_target | ITGA6_ITGB1_receptor | 4.012e-06 | 0.01 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Skeletal,muscle(Good)_source | LAMA3_ligand | Neurons(Nos)_target | ITGA6_ITGB1_receptor | 7.321e-05 | 0.02 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Skeletal,muscle(Good)_source | LAMA3_ligand | Neutrophils(Nos)_target | ITGA6_ITGB1_receptor | 5.882e-07 | 0.04 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Skeletal,muscle(Good)_source | LAMA3_ligand | Skeletal,muscle(Good)_target | ITGA6_ITGB1_receptor | 7.125e-06 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Skeletal,muscle(Good)_source | LAMA3_ligand | Skeletal,muscle(Nos)_target | ITGA6_ITGB1_receptor | 4.419e-05 | 0.02 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Chondrocytes(Nos)_source | LAMB1_ligand | B-cells(Nos)_target | ITGA6_ITGB1_receptor | 2.286e-07 | 0.01 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Chondrocytes(Nos)_source | LAMB1_ligand | Chondrocytes(Nos)_target | ITGA6_ITGB1_receptor | 9.662e-06 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Chondrocytes(Nos)_source | LAMB1_ligand | Neurons(Good)_target | ITGA6_ITGB1_receptor | 3.962e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Chondrocytes(Nos)_source | LAMB1_ligand | Neurons(Nos)_target | ITGA6_ITGB1_receptor | 7.197e-04 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Chondrocytes(Nos)_source | LAMB1_ligand | Neutrophils(Nos)_target | ITGA6_ITGB1_receptor | 5.945e-06 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Chondrocytes(Nos)_source | LAMB1_ligand | Skeletal,muscle(Good)_target | ITGA6_ITGB1_receptor | 6.752e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Chondrocytes(Nos)_source | LAMB1_ligand | Skeletal,muscle(Nos)_target | ITGA6_ITGB1_receptor | 4.376e-04 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Skeletal,muscle(Good)_source | LAMA3_ligand | B-cells(Nos)_target | ITGA6_ITGB4_receptor | 5.142e-09 | 0.04 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Skeletal,muscle(Good)_source | LAMA3_ligand | Chondrocytes(Nos)_target | ITGA6_ITGB4_receptor | 1.482e-06 | 0.04 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Skeletal,muscle(Good)_source | LAMA3_ligand | Neurons(Good)_target | ITGA6_ITGB4_receptor | 7.613e-06 | 0.01 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Skeletal,muscle(Good)_source | LAMA3_ligand | Neurons(Nos)_target | ITGA6_ITGB4_receptor | 1.450e-04 | 0.02 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Skeletal,muscle(Good)_source | LAMA3_ligand | Neutrophils(Nos)_target | ITGA6_ITGB4_receptor | 1.208e-06 | 0.04 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Skeletal,muscle(Good)_source | LAMA3_ligand | Skeletal,muscle(Good)_target | ITGA6_ITGB4_receptor | 9.423e-06 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Skeletal,muscle(Good)_source | LAMA3_ligand | Skeletal,muscle(Nos)_target | ITGA6_ITGB4_receptor | 9.333e-05 | 0.02 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Chondrocytes(Nos)_source | LAMB1_ligand | B-cells(Nos)_target | ITGA6_ITGB4_receptor | 5.244e-08 | 0.01 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Chondrocytes(Nos)_source | LAMB1_ligand | Chondrocytes(Nos)_target | ITGA6_ITGB4_receptor | 1.497e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Chondrocytes(Nos)_source | LAMB1_ligand | Neurons(Good)_target | ITGA6_ITGB4_receptor | 7.310e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Chondrocytes(Nos)_source | LAMB1_ligand | Neurons(Nos)_target | ITGA6_ITGB4_receptor | 1.377e-03 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Chondrocytes(Nos)_source | LAMB1_ligand | Neutrophils(Nos)_target | ITGA6_ITGB4_receptor | 1.210e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Chondrocytes(Nos)_source | LAMB1_ligand | Skeletal,muscle(Good)_target | ITGA6_ITGB4_receptor | 8.731e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Chondrocytes(Nos)_source | LAMB1_ligand | Skeletal,muscle(Nos)_target | ITGA6_ITGB4_receptor | 8.953e-04 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Skeletal,muscle(Good)_source | LAMA3_ligand | B-cells(Nos)_target | CD44_receptor | 5.168e-08 | 0.04 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Skeletal,muscle(Good)_source | LAMA3_ligand | Chondrocytes(Nos)_target | CD44_receptor | 7.048e-08 | 0.04 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Skeletal,muscle(Good)_source | LAMA3_ligand | Neurons(Good)_target | CD44_receptor | 3.661e-06 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Skeletal,muscle(Good)_source | LAMA3_ligand | Neurons(Nos)_target | CD44_receptor | 6.983e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Skeletal,muscle(Good)_source | LAMA3_ligand | Neutrophils(Nos)_target | CD44_receptor | 2.178e-08 | 0.04 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Skeletal,muscle(Good)_source | LAMA3_ligand | Skeletal,muscle(Good)_target | CD44_receptor | 2.893e-06 | 0.01 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Skeletal,muscle(Good)_source | LAMA3_ligand | Skeletal,muscle(Nos)_target | CD44_receptor | 1.147e-06 | 0.04 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Chondrocytes(Nos)_source | LAMB1_ligand | B-cells(Nos)_target | CD44_receptor | 5.270e-07 | 0.01 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Chondrocytes(Nos)_source | LAMB1_ligand | Chondrocytes(Nos)_target | CD44_receptor | 7.184e-07 | 0.01 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Chondrocytes(Nos)_source | LAMB1_ligand | Neurons(Good)_target | CD44_receptor | 3.626e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Chondrocytes(Nos)_source | LAMB1_ligand | Neurons(Nos)_target | CD44_receptor | 6.876e-04 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Chondrocytes(Nos)_source | LAMB1_ligand | Neutrophils(Nos)_target | CD44_receptor | 2.221e-07 | 0.01 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Chondrocytes(Nos)_source | LAMB1_ligand | Skeletal,muscle(Good)_target | CD44_receptor | 2.862e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Chondrocytes(Nos)_source | LAMB1_ligand | Skeletal,muscle(Nos)_target | CD44_receptor | 1.169e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Neurons(Nos)_source | CDH1_ligand | Neurons(Good)_target | CDH1_receptor | 9.714e-05 | 0.03 | CDH | Cell-Cell Contact | KEGG: hsa04514 |
| Skeletal,muscle(Good)_source | CDH1_ligand | Neurons(Good)_target | CDH1_receptor | 1.022e-05 | 0.0 | CDH | Cell-Cell Contact | KEGG: hsa04514 |
| Skeletal,muscle(Nos)_source | CDH1_ligand | Neurons(Good)_target | CDH1_receptor | 7.286e-05 | 0.02 | CDH | Cell-Cell Contact | KEGG: hsa04514 |
| Neurons(Good)_source | CDH1_ligand | Neurons(Nos)_target | CDH1_receptor | 9.714e-05 | 0.03 | CDH | Cell-Cell Contact | KEGG: hsa04514 |
| Neurons(Nos)_source | CDH1_ligand | Neurons(Nos)_target | CDH1_receptor | 1.594e-03 | 0.0 | CDH | Cell-Cell Contact | KEGG: hsa04514 |
| Skeletal,muscle(Good)_source | CDH1_ligand | Neurons(Nos)_target | CDH1_receptor | 1.678e-04 | 0.0 | CDH | Cell-Cell Contact | KEGG: hsa04514 |
| Skeletal,muscle(Nos)_source | CDH1_ligand | Neurons(Nos)_target | CDH1_receptor | 1.196e-03 | 0.0 | CDH | Cell-Cell Contact | KEGG: hsa04514 |
| Neurons(Good)_source | CDH1_ligand | Skeletal,muscle(Good)_target | CDH1_receptor | 1.022e-05 | 0.0 | CDH | Cell-Cell Contact | KEGG: hsa04514 |
| Neurons(Nos)_source | CDH1_ligand | Skeletal,muscle(Good)_target | CDH1_receptor | 1.678e-04 | 0.0 | CDH | Cell-Cell Contact | KEGG: hsa04514 |
| Skeletal,muscle(Good)_source | CDH1_ligand | Skeletal,muscle(Good)_target | CDH1_receptor | 1.746e-05 | 0.0 | CDH | Cell-Cell Contact | KEGG: hsa04514 |
| Skeletal,muscle(Nos)_source | CDH1_ligand | Skeletal,muscle(Good)_target | CDH1_receptor | 1.258e-04 | 0.0 | CDH | Cell-Cell Contact | KEGG: hsa04514 |
| Neurons(Good)_source | CDH1_ligand | Skeletal,muscle(Nos)_target | CDH1_receptor | 7.286e-05 | 0.02 | CDH | Cell-Cell Contact | KEGG: hsa04514 |
| Neurons(Nos)_source | CDH1_ligand | Skeletal,muscle(Nos)_target | CDH1_receptor | 1.196e-03 | 0.0 | CDH | Cell-Cell Contact | KEGG: hsa04514 |
| Skeletal,muscle(Good)_source | CDH1_ligand | Skeletal,muscle(Nos)_target | CDH1_receptor | 1.258e-04 | 0.0 | CDH | Cell-Cell Contact | KEGG: hsa04514 |
| Skeletal,muscle(Nos)_source | CDH1_ligand | Skeletal,muscle(Nos)_target | CDH1_receptor | 8.971e-04 | 0.0 | CDH | Cell-Cell Contact | KEGG: hsa04514 |
| Neurons(Nos)_source | CDH1_ligand | Neurons(Good)_target | ITGA2_ITGB1_receptor | 3.173e-05 | 0.02 | CDH1 | Cell-Cell Contact | PMID: 12392763 |
| Skeletal,muscle(Good)_source | CDH1_ligand | Neurons(Good)_target | ITGA2_ITGB1_receptor | 3.360e-06 | 0.0 | CDH1 | Cell-Cell Contact | PMID: 12392763 |
| Skeletal,muscle(Nos)_source | CDH1_ligand | Neurons(Good)_target | ITGA2_ITGB1_receptor | 2.380e-05 | 0.01 | CDH1 | Cell-Cell Contact | PMID: 12392763 |
| Neurons(Good)_source | CDH1_ligand | Neurons(Nos)_target | ITGA2_ITGB1_receptor | 3.391e-05 | 0.01 | CDH1 | Cell-Cell Contact | PMID: 12392763 |
| Neurons(Nos)_source | CDH1_ligand | Neurons(Nos)_target | ITGA2_ITGB1_receptor | 5.566e-04 | 0.0 | CDH1 | Cell-Cell Contact | PMID: 12392763 |
| Skeletal,muscle(Good)_source | CDH1_ligand | Neurons(Nos)_target | ITGA2_ITGB1_receptor | 5.891e-05 | 0.0 | CDH1 | Cell-Cell Contact | PMID: 12392763 |
| Skeletal,muscle(Nos)_source | CDH1_ligand | Neurons(Nos)_target | ITGA2_ITGB1_receptor | 4.175e-04 | 0.0 | CDH1 | Cell-Cell Contact | PMID: 12392763 |
| Neurons(Good)_source | CDH1_ligand | Skeletal,muscle(Good)_target | ITGA2_ITGB1_receptor | 4.712e-06 | 0.0 | CDH1 | Cell-Cell Contact | PMID: 12392763 |
| Neurons(Nos)_source | CDH1_ligand | Skeletal,muscle(Good)_target | ITGA2_ITGB1_receptor | 7.734e-05 | 0.0 | CDH1 | Cell-Cell Contact | PMID: 12392763 |
| Skeletal,muscle(Good)_source | CDH1_ligand | Skeletal,muscle(Good)_target | ITGA2_ITGB1_receptor | 8.136e-06 | 0.0 | CDH1 | Cell-Cell Contact | PMID: 12392763 |
| Skeletal,muscle(Nos)_source | CDH1_ligand | Skeletal,muscle(Good)_target | ITGA2_ITGB1_receptor | 5.801e-05 | 0.0 | CDH1 | Cell-Cell Contact | PMID: 12392763 |
| Neurons(Nos)_source | CDH1_ligand | Skeletal,muscle(Nos)_target | ITGA2_ITGB1_receptor | 3.383e-04 | 0.0 | CDH1 | Cell-Cell Contact | PMID: 12392763 |
| Skeletal,muscle(Good)_source | CDH1_ligand | Skeletal,muscle(Nos)_target | ITGA2_ITGB1_receptor | 3.583e-05 | 0.0 | CDH1 | Cell-Cell Contact | PMID: 12392763 |
| Skeletal,muscle(Nos)_source | CDH1_ligand | Skeletal,muscle(Nos)_target | ITGA2_ITGB1_receptor | 2.537e-04 | 0.01 | CDH1 | Cell-Cell Contact | PMID: 12392763 |
| Skeletal,muscle(Good)_source | DSC2_ligand | Skeletal,muscle(Good)_target | DSG2_receptor | 3.593e-06 | 0.0 | DESMOSOME | Cell-Cell Contact | PMID: 27298358 |
| Neurons(Good)_source | EFNA5_ligand | Chondrocytes(Nos)_target | EPHA4_receptor | 8.635e-07 | 0.0 | EPHA | Cell-Cell Contact | PMID: 15114347 |
| Neurons(Nos)_source | EFNA5_ligand | Chondrocytes(Nos)_target | EPHA4_receptor | 3.421e-06 | 0.0 | EPHA | Cell-Cell Contact | PMID: 15114347 |
| Chondrocytes(Nos)_source | EFNA5_ligand | Neurons(Good)_target | EPHA4_receptor | 6.484e-07 | 0.0 | EPHA | Cell-Cell Contact | PMID: 15114347 |
| Neurons(Good)_source | EFNA5_ligand | Neurons(Good)_target | EPHA4_receptor | 1.603e-06 | 0.0 | EPHA | Cell-Cell Contact | PMID: 15114347 |
| Neurons(Nos)_source | EFNA5_ligand | Neurons(Good)_target | EPHA4_receptor | 6.357e-06 | 0.0 | EPHA | Cell-Cell Contact | PMID: 15114347 |
| Neutrophils(Nos)_source | EFNA5_ligand | Neurons(Good)_target | EPHA4_receptor | 2.387e-07 | 0.04 | EPHA | Cell-Cell Contact | PMID: 15114347 |
| Skeletal,muscle(Good)_source | EFNA5_ligand | Neurons(Good)_target | EPHA4_receptor | 3.896e-07 | 0.01 | EPHA | Cell-Cell Contact | PMID: 15114347 |
| Chondrocytes(Nos)_source | EFNA5_ligand | Neurons(Nos)_target | EPHA4_receptor | 5.182e-06 | 0.0 | EPHA | Cell-Cell Contact | PMID: 15114347 |
| Neurons(Good)_source | EFNA5_ligand | Neurons(Nos)_target | EPHA4_receptor | 1.282e-05 | 0.0 | EPHA | Cell-Cell Contact | PMID: 15114347 |
| Neurons(Nos)_source | EFNA5_ligand | Neurons(Nos)_target | EPHA4_receptor | 5.081e-05 | 0.0 | EPHA | Cell-Cell Contact | PMID: 15114347 |
| Skeletal,muscle(Good)_source | EFNA5_ligand | Neurons(Nos)_target | EPHA4_receptor | 3.114e-06 | 0.04 | EPHA | Cell-Cell Contact | PMID: 15114347 |
| Chondrocytes(Nos)_source | EFNA5_ligand | Neutrophils(Nos)_target | EPHA4_receptor | 1.360e-06 | 0.0 | EPHA | Cell-Cell Contact | PMID: 15114347 |
| Neurons(Good)_source | EFNA5_ligand | Neutrophils(Nos)_target | EPHA4_receptor | 3.349e-06 | 0.0 | EPHA | Cell-Cell Contact | PMID: 15114347 |
| Neurons(Nos)_source | EFNA5_ligand | Neutrophils(Nos)_target | EPHA4_receptor | 1.333e-05 | 0.0 | EPHA | Cell-Cell Contact | PMID: 15114347 |
| Neutrophils(Nos)_source | EFNA5_ligand | Neutrophils(Nos)_target | EPHA4_receptor | 5.007e-07 | 0.0 | EPHA | Cell-Cell Contact | PMID: 15114347 |
| Skeletal,muscle(Good)_source | EFNA5_ligand | Neutrophils(Nos)_target | EPHA4_receptor | 8.169e-07 | 0.0 | EPHA | Cell-Cell Contact | PMID: 15114347 |
| Chondrocytes(Nos)_source | EFNA5_ligand | Skeletal,muscle(Good)_target | EPHA4_receptor | 1.010e-06 | 0.0 | EPHA | Cell-Cell Contact | PMID: 15114347 |
| Neurons(Good)_source | EFNA5_ligand | Skeletal,muscle(Good)_target | EPHA4_receptor | 2.494e-06 | 0.0 | EPHA | Cell-Cell Contact | PMID: 15114347 |
| Neurons(Nos)_source | EFNA5_ligand | Skeletal,muscle(Good)_target | EPHA4_receptor | 9.903e-06 | 0.0 | EPHA | Cell-Cell Contact | PMID: 15114347 |
| Neutrophils(Nos)_source | EFNA5_ligand | Skeletal,muscle(Good)_target | EPHA4_receptor | 3.719e-07 | 0.0 | EPHA | Cell-Cell Contact | PMID: 15114347 |
| Skeletal,muscle(Good)_source | EFNA5_ligand | Skeletal,muscle(Good)_target | EPHA4_receptor | 6.068e-07 | 0.0 | EPHA | Cell-Cell Contact | PMID: 15114347 |
| Chondrocytes(Nos)_source | EFNA5_ligand | Skeletal,muscle(Nos)_target | EPHA4_receptor | 3.054e-06 | 0.02 | EPHA | Cell-Cell Contact | PMID: 15114347 |
| Neurons(Good)_source | EFNA5_ligand | Skeletal,muscle(Nos)_target | EPHA4_receptor | 7.558e-06 | 0.01 | EPHA | Cell-Cell Contact | PMID: 15114347 |
| Neurons(Nos)_source | EFNA5_ligand | Skeletal,muscle(Nos)_target | EPHA4_receptor | 2.994e-05 | 0.0 | EPHA | Cell-Cell Contact | PMID: 15114347 |
| Chondrocytes(Nos)_source | EFNA5_ligand | Neurons(Good)_target | EPHB2_receptor | 1.926e-06 | 0.02 | EPHA | Cell-Cell Contact | PMID:15107857; PMID: 15114347 |
| Neurons(Good)_source | EFNA5_ligand | Neurons(Good)_target | EPHB2_receptor | 4.750e-06 | 0.0 | EPHA | Cell-Cell Contact | PMID:15107857; PMID: 15114347 |
| Neurons(Nos)_source | EFNA5_ligand | Neurons(Good)_target | EPHB2_receptor | 1.889e-05 | 0.0 | EPHA | Cell-Cell Contact | PMID:15107857; PMID: 15114347 |
| Skeletal,muscle(Good)_source | EFNA5_ligand | Neurons(Good)_target | EPHB2_receptor | 1.157e-06 | 0.03 | EPHA | Cell-Cell Contact | PMID:15107857; PMID: 15114347 |
| Chondrocytes(Nos)_source | EFNA5_ligand | Neurons(Nos)_target | EPHB2_receptor | 3.591e-05 | 0.0 | EPHA | Cell-Cell Contact | PMID:15107857; PMID: 15114347 |
| Neurons(Good)_source | EFNA5_ligand | Neurons(Nos)_target | EPHB2_receptor | 8.851e-05 | 0.0 | EPHA | Cell-Cell Contact | PMID:15107857; PMID: 15114347 |
| Neurons(Nos)_source | EFNA5_ligand | Neurons(Nos)_target | EPHB2_receptor | 3.522e-04 | 0.0 | EPHA | Cell-Cell Contact | PMID:15107857; PMID: 15114347 |
| Skeletal,muscle(Good)_source | EFNA5_ligand | Neurons(Nos)_target | EPHB2_receptor | 2.158e-05 | 0.03 | EPHA | Cell-Cell Contact | PMID:15107857; PMID: 15114347 |
| Chondrocytes(Nos)_source | EFNA5_ligand | Skeletal,muscle(Good)_target | EPHB2_receptor | 1.421e-06 | 0.02 | EPHA | Cell-Cell Contact | PMID:15107857; PMID: 15114347 |
| Neurons(Good)_source | EFNA5_ligand | Skeletal,muscle(Good)_target | EPHB2_receptor | 3.504e-06 | 0.01 | EPHA | Cell-Cell Contact | PMID:15107857; PMID: 15114347 |
| Neurons(Nos)_source | EFNA5_ligand | Skeletal,muscle(Good)_target | EPHB2_receptor | 1.393e-05 | 0.01 | EPHA | Cell-Cell Contact | PMID:15107857; PMID: 15114347 |
| Skeletal,muscle(Good)_source | EFNA5_ligand | Skeletal,muscle(Good)_target | EPHB2_receptor | 8.536e-07 | 0.04 | EPHA | Cell-Cell Contact | PMID:15107857; PMID: 15114347 |
| Neurons(Good)_source | EFNA5_ligand | Skeletal,muscle(Nos)_target | EPHB2_receptor | 3.503e-05 | 0.02 | EPHA | Cell-Cell Contact | PMID:15107857; PMID: 15114347 |
| Skeletal,muscle(Good)_source | EFNB2_ligand | Chondrocytes(Nos)_target | EPHA4_receptor | 3.847e-07 | 0.01 | EPHB | Cell-Cell Contact | PMID: 15114347 |
| Neurons(Good)_source | EFNB2_ligand | Neurons(Good)_target | EPHA4_receptor | 4.049e-07 | 0.01 | EPHB | Cell-Cell Contact | PMID: 15114347 |
| Neurons(Nos)_source | EFNB2_ligand | Neurons(Good)_target | EPHA4_receptor | 7.066e-06 | 0.0 | EPHB | Cell-Cell Contact | PMID: 15114347 |
| Skeletal,muscle(Good)_source | EFNB2_ligand | Neurons(Good)_target | EPHA4_receptor | 7.146e-07 | 0.0 | EPHB | Cell-Cell Contact | PMID: 15114347 |
| Skeletal,muscle(Nos)_source | EFNB2_ligand | Neurons(Good)_target | EPHA4_receptor | 3.475e-06 | 0.0 | EPHB | Cell-Cell Contact | PMID: 15114347 |
| Neurons(Nos)_source | EFNB2_ligand | Neurons(Nos)_target | EPHA4_receptor | 5.647e-05 | 0.0 | EPHB | Cell-Cell Contact | PMID: 15114347 |
| Skeletal,muscle(Good)_source | EFNB2_ligand | Neurons(Nos)_target | EPHA4_receptor | 5.713e-06 | 0.01 | EPHB | Cell-Cell Contact | PMID: 15114347 |
| Neurons(Good)_source | EFNB2_ligand | Neutrophils(Nos)_target | EPHA4_receptor | 8.494e-07 | 0.0 | EPHB | Cell-Cell Contact | PMID: 15114347 |
| Neurons(Nos)_source | EFNB2_ligand | Neutrophils(Nos)_target | EPHA4_receptor | 1.482e-05 | 0.0 | EPHB | Cell-Cell Contact | PMID: 15114347 |
| Neutrophils(Nos)_source | EFNB2_ligand | Neutrophils(Nos)_target | EPHA4_receptor | 4.776e-07 | 0.0 | EPHB | Cell-Cell Contact | PMID: 15114347 |
| Skeletal,muscle(Good)_source | EFNB2_ligand | Neutrophils(Nos)_target | EPHA4_receptor | 1.496e-06 | 0.0 | EPHB | Cell-Cell Contact | PMID: 15114347 |
| Skeletal,muscle(Nos)_source | EFNB2_ligand | Neutrophils(Nos)_target | EPHA4_receptor | 7.293e-06 | 0.0 | EPHB | Cell-Cell Contact | PMID: 15114347 |
| Neurons(Good)_source | EFNB2_ligand | Skeletal,muscle(Good)_target | EPHA4_receptor | 6.308e-07 | 0.0 | EPHB | Cell-Cell Contact | PMID: 15114347 |
| Neurons(Nos)_source | EFNB2_ligand | Skeletal,muscle(Good)_target | EPHA4_receptor | 1.101e-05 | 0.0 | EPHB | Cell-Cell Contact | PMID: 15114347 |
| Neutrophils(Nos)_source | EFNB2_ligand | Skeletal,muscle(Good)_target | EPHA4_receptor | 3.547e-07 | 0.0 | EPHB | Cell-Cell Contact | PMID: 15114347 |
| Skeletal,muscle(Good)_source | EFNB2_ligand | Skeletal,muscle(Good)_target | EPHA4_receptor | 1.112e-06 | 0.0 | EPHB | Cell-Cell Contact | PMID: 15114347 |
| Skeletal,muscle(Nos)_source | EFNB2_ligand | Skeletal,muscle(Good)_target | EPHA4_receptor | 5.414e-06 | 0.0 | EPHB | Cell-Cell Contact | PMID: 15114347 |
| Neurons(Nos)_source | EFNB2_ligand | Skeletal,muscle(Nos)_target | EPHA4_receptor | 3.328e-05 | 0.01 | EPHB | Cell-Cell Contact | PMID: 15114347 |
| Skeletal,muscle(Good)_source | EFNB2_ligand | Skeletal,muscle(Nos)_target | EPHA4_receptor | 3.367e-06 | 0.02 | EPHB | Cell-Cell Contact | PMID: 15114347 |
| Neurons(Nos)_source | EFNB2_ligand | Neurons(Good)_target | EPHB2_receptor | 2.099e-05 | 0.02 | EPHB | Cell-Cell Contact | PMID: 15114347 |
| Skeletal,muscle(Good)_source | EFNB2_ligand | Neurons(Good)_target | EPHB2_receptor | 2.121e-06 | 0.01 | EPHB | Cell-Cell Contact | PMID: 15114347 |
| Neurons(Good)_source | EFNB2_ligand | Neurons(Nos)_target | EPHB2_receptor | 2.243e-05 | 0.04 | EPHB | Cell-Cell Contact | PMID: 15114347 |
| Neurons(Nos)_source | EFNB2_ligand | Neurons(Nos)_target | EPHB2_receptor | 3.914e-04 | 0.0 | EPHB | Cell-Cell Contact | PMID: 15114347 |
| Skeletal,muscle(Good)_source | EFNB2_ligand | Neurons(Nos)_target | EPHB2_receptor | 3.953e-05 | 0.01 | EPHB | Cell-Cell Contact | PMID: 15114347 |
| Skeletal,muscle(Good)_source | EFNB2_ligand | Skeletal,muscle(Good)_target | EPHB2_receptor | 1.564e-06 | 0.01 | EPHB | Cell-Cell Contact | PMID: 15114347 |
| Skeletal,muscle(Good)_source | EFNB2_ligand | Skeletal,muscle(Nos)_target | EPHB2_receptor | 1.562e-05 | 0.03 | EPHB | Cell-Cell Contact | PMID: 15114347 |
| Skeletal,muscle(Good)_source | MPZL1_ligand | Neurons(Good)_target | MPZL1_receptor | 2.379e-07 | 0.01 | MPZ | Cell-Cell Contact | KEGG: hsa04514 |
| Neurons(Nos)_source | MPZL1_ligand | Neurons(Nos)_target | MPZL1_receptor | 1.099e-05 | 0.0 | MPZ | Cell-Cell Contact | KEGG: hsa04514 |
| Skeletal,muscle(Good)_source | MPZL1_ligand | Neurons(Nos)_target | MPZL1_receptor | 3.650e-06 | 0.0 | MPZ | Cell-Cell Contact | KEGG: hsa04514 |
| Skeletal,muscle(Nos)_source | MPZL1_ligand | Neurons(Nos)_target | MPZL1_receptor | 7.116e-06 | 0.0 | MPZ | Cell-Cell Contact | KEGG: hsa04514 |
| Neurons(Good)_source | MPZL1_ligand | Skeletal,muscle(Good)_target | MPZL1_receptor | 2.379e-07 | 0.01 | MPZ | Cell-Cell Contact | KEGG: hsa04514 |
| Neurons(Nos)_source | MPZL1_ligand | Skeletal,muscle(Good)_target | MPZL1_receptor | 3.650e-06 | 0.0 | MPZ | Cell-Cell Contact | KEGG: hsa04514 |
| Skeletal,muscle(Good)_source | MPZL1_ligand | Skeletal,muscle(Good)_target | MPZL1_receptor | 1.210e-06 | 0.01 | MPZ | Cell-Cell Contact | KEGG: hsa04514 |
| Skeletal,muscle(Nos)_source | MPZL1_ligand | Skeletal,muscle(Good)_target | MPZL1_receptor | 2.363e-06 | 0.0 | MPZ | Cell-Cell Contact | KEGG: hsa04514 |
| Neurons(Nos)_source | MPZL1_ligand | Skeletal,muscle(Nos)_target | MPZL1_receptor | 7.116e-06 | 0.0 | MPZ | Cell-Cell Contact | KEGG: hsa04514 |
| Skeletal,muscle(Good)_source | MPZL1_ligand | Skeletal,muscle(Nos)_target | MPZL1_receptor | 2.363e-06 | 0.0 | MPZ | Cell-Cell Contact | KEGG: hsa04514 |
| Skeletal,muscle(Nos)_source | MPZL1_ligand | Skeletal,muscle(Nos)_target | MPZL1_receptor | 4.607e-06 | 0.01 | MPZ | Cell-Cell Contact | KEGG: hsa04514 |
| Skeletal,muscle(Good)_source | OCLN_ligand | Chondrocytes(Nos)_target | OCLN_receptor | 1.807e-08 | 0.01 | OCLN | Cell-Cell Contact | KEGG: hsa04514 |
| Neurons(Good)_source | OCLN_ligand | Neurons(Good)_target | OCLN_receptor | 2.659e-09 | 0.01 | OCLN | Cell-Cell Contact | KEGG: hsa04514 |
| Neurons(Nos)_source | OCLN_ligand | Neurons(Good)_target | OCLN_receptor | 4.070e-08 | 0.0 | OCLN | Cell-Cell Contact | KEGG: hsa04514 |
| Skeletal,muscle(Good)_source | OCLN_ligand | Neurons(Good)_target | OCLN_receptor | 3.220e-08 | 0.0 | OCLN | Cell-Cell Contact | KEGG: hsa04514 |
| Skeletal,muscle(Nos)_source | OCLN_ligand | Neurons(Good)_target | OCLN_receptor | 2.875e-08 | 0.0 | OCLN | Cell-Cell Contact | KEGG: hsa04514 |
| Neurons(Good)_source | OCLN_ligand | Neurons(Nos)_target | OCLN_receptor | 4.070e-08 | 0.0 | OCLN | Cell-Cell Contact | KEGG: hsa04514 |
| Neurons(Nos)_source | OCLN_ligand | Neurons(Nos)_target | OCLN_receptor | 6.228e-07 | 0.0 | OCLN | Cell-Cell Contact | KEGG: hsa04514 |
| Skeletal,muscle(Good)_source | OCLN_ligand | Neurons(Nos)_target | OCLN_receptor | 4.928e-07 | 0.0 | OCLN | Cell-Cell Contact | KEGG: hsa04514 |
| Skeletal,muscle(Nos)_source | OCLN_ligand | Neurons(Nos)_target | OCLN_receptor | 4.400e-07 | 0.0 | OCLN | Cell-Cell Contact | KEGG: hsa04514 |
| Skeletal,muscle(Good)_source | OCLN_ligand | Neutrophils(Nos)_target | OCLN_receptor | 6.894e-09 | 0.01 | OCLN | Cell-Cell Contact | KEGG: hsa04514 |
| Chondrocytes(Nos)_source | OCLN_ligand | Skeletal,muscle(Good)_target | OCLN_receptor | 1.807e-08 | 0.01 | OCLN | Cell-Cell Contact | KEGG: hsa04514 |
| Neurons(Good)_source | OCLN_ligand | Skeletal,muscle(Good)_target | OCLN_receptor | 3.220e-08 | 0.0 | OCLN | Cell-Cell Contact | KEGG: hsa04514 |
| Neurons(Nos)_source | OCLN_ligand | Skeletal,muscle(Good)_target | OCLN_receptor | 4.928e-07 | 0.0 | OCLN | Cell-Cell Contact | KEGG: hsa04514 |
| Neutrophils(Nos)_source | OCLN_ligand | Skeletal,muscle(Good)_target | OCLN_receptor | 6.894e-09 | 0.01 | OCLN | Cell-Cell Contact | KEGG: hsa04514 |
| Skeletal,muscle(Good)_source | OCLN_ligand | Skeletal,muscle(Good)_target | OCLN_receptor | 3.897e-07 | 0.0 | OCLN | Cell-Cell Contact | KEGG: hsa04514 |
| Skeletal,muscle(Nos)_source | OCLN_ligand | Skeletal,muscle(Good)_target | OCLN_receptor | 3.482e-07 | 0.01 | OCLN | Cell-Cell Contact | KEGG: hsa04514 |
| Neurons(Good)_source | OCLN_ligand | Skeletal,muscle(Nos)_target | OCLN_receptor | 2.875e-08 | 0.0 | OCLN | Cell-Cell Contact | KEGG: hsa04514 |
| Neurons(Nos)_source | OCLN_ligand | Skeletal,muscle(Nos)_target | OCLN_receptor | 4.400e-07 | 0.0 | OCLN | Cell-Cell Contact | KEGG: hsa04514 |
| Skeletal,muscle(Good)_source | OCLN_ligand | Skeletal,muscle(Nos)_target | OCLN_receptor | 3.482e-07 | 0.01 | OCLN | Cell-Cell Contact | KEGG: hsa04514 |
| Neurons(Nos)_source | SEMA6A_ligand | Neurons(Good)_target | PLXNA2_receptor | 1.326e-04 | 0.0 | SEMA6 | Cell-Cell Contact | PMID: 27533782 |
| Skeletal,muscle(Good)_source | SEMA6A_ligand | Neurons(Good)_target | PLXNA2_receptor | 1.563e-05 | 0.0 | SEMA6 | Cell-Cell Contact | PMID: 27533782 |
| Skeletal,muscle(Nos)_source | SEMA6A_ligand | Neurons(Good)_target | PLXNA2_receptor | 1.039e-04 | 0.0 | SEMA6 | Cell-Cell Contact | PMID: 27533782 |
| Neurons(Good)_source | SEMA6A_ligand | Neurons(Nos)_target | PLXNA2_receptor | 1.170e-04 | 0.0 | SEMA6 | Cell-Cell Contact | PMID: 27533782 |
| Neurons(Nos)_source | SEMA6A_ligand | Neurons(Nos)_target | PLXNA2_receptor | 1.838e-03 | 0.0 | SEMA6 | Cell-Cell Contact | PMID: 27533782 |
| Skeletal,muscle(Good)_source | SEMA6A_ligand | Neurons(Nos)_target | PLXNA2_receptor | 2.170e-04 | 0.0 | SEMA6 | Cell-Cell Contact | PMID: 27533782 |
| Skeletal,muscle(Nos)_source | SEMA6A_ligand | Neurons(Nos)_target | PLXNA2_receptor | 1.439e-03 | 0.0 | SEMA6 | Cell-Cell Contact | PMID: 27533782 |
| Neurons(Good)_source | SEMA6A_ligand | Skeletal,muscle(Good)_target | PLXNA2_receptor | 9.684e-06 | 0.0 | SEMA6 | Cell-Cell Contact | PMID: 27533782 |
| Neurons(Nos)_source | SEMA6A_ligand | Skeletal,muscle(Good)_target | PLXNA2_receptor | 1.521e-04 | 0.0 | SEMA6 | Cell-Cell Contact | PMID: 27533782 |
| Skeletal,muscle(Good)_source | SEMA6A_ligand | Skeletal,muscle(Good)_target | PLXNA2_receptor | 1.779e-05 | 0.0 | SEMA6 | Cell-Cell Contact | PMID: 27533782 |
| Skeletal,muscle(Nos)_source | SEMA6A_ligand | Skeletal,muscle(Good)_target | PLXNA2_receptor | 1.191e-04 | 0.0 | SEMA6 | Cell-Cell Contact | PMID: 27533782 |
| Neurons(Good)_source | SEMA6A_ligand | Skeletal,muscle(Nos)_target | PLXNA2_receptor | 7.920e-05 | 0.04 | SEMA6 | Cell-Cell Contact | PMID: 27533782 |
| Neurons(Nos)_source | SEMA6A_ligand | Skeletal,muscle(Nos)_target | PLXNA2_receptor | 1.244e-03 | 0.0 | SEMA6 | Cell-Cell Contact | PMID: 27533782 |
| Skeletal,muscle(Good)_source | SEMA6A_ligand | Skeletal,muscle(Nos)_target | PLXNA2_receptor | 1.471e-04 | 0.0 | SEMA6 | Cell-Cell Contact | PMID: 27533782 |
| Skeletal,muscle(Nos)_source | SEMA6A_ligand | Skeletal,muscle(Nos)_target | PLXNA2_receptor | 9.741e-04 | 0.0 | SEMA6 | Cell-Cell Contact | PMID: 27533782 |