Sample overview

Project Name	TCGA-COAD
GSE ID	GSE201348
GSM ID	GSM6061677
Cell Line	None
Tissue type	Colon
Disease Type	Polyp
PMID	35726067
Initial gene number	33538
Initial cell number	3650
Post-QC gene number	976
Post-QC cell number	3511

QC Metrics

Bulk-to-ScRNA-seq Label Transfer

Bulk phenotype-associated subpopulations

Reference-Based Annotation

Differentially expressed genes

Overall Survival : Cluster vs

Overall Survival : Cluster vs ( + )

Clinical Stage : Cluster vs

Tumor Size : Cluster vs

Lymph Node Involvement : Cluster vs

Distant Metastasis : Cluster vs

Cell-Cell communications ( Survival-Associated Subpopulations Across Cell Types )

Cell Population Signaling and Communication

Ligand-Receptor-Mediated Cell-Cell Interactions

Sending Cell Type	Ligand	Receiving Cell Type	Receptor	Score	P-value	Pathway Name	Function	Evidence
Chondrocytes(Good)_source	CDH1_ligand	Adipocytes(Good)_target	CDH1_receptor	1.941e-08	0.03	CDH	Cell-Cell Contact	KEGG: hsa04514
Chondrocytes(Nos)_source	CDH1_ligand	Adipocytes(Good)_target	CDH1_receptor	2.660e-07	0.0	CDH	Cell-Cell Contact	KEGG: hsa04514
Chondrocytes(Good)_source	CDH1_ligand	Adipocytes(Nos)_target	CDH1_receptor	2.930e-07	0.0	CDH	Cell-Cell Contact	KEGG: hsa04514
Chondrocytes(Nos)_source	CDH1_ligand	Adipocytes(Nos)_target	CDH1_receptor	4.016e-06	0.0	CDH	Cell-Cell Contact	KEGG: hsa04514
Adipocytes(Good)_source	CDH1_ligand	Chondrocytes(Good)_target	CDH1_receptor	1.941e-08	0.03	CDH	Cell-Cell Contact	KEGG: hsa04514
Adipocytes(Nos)_source	CDH1_ligand	Chondrocytes(Good)_target	CDH1_receptor	2.930e-07	0.0	CDH	Cell-Cell Contact	KEGG: hsa04514
Chondrocytes(Good)_source	CDH1_ligand	Chondrocytes(Good)_target	CDH1_receptor	5.603e-07	0.0	CDH	Cell-Cell Contact	KEGG: hsa04514
Chondrocytes(Nos)_source	CDH1_ligand	Chondrocytes(Good)_target	CDH1_receptor	7.726e-06	0.0	CDH	Cell-Cell Contact	KEGG: hsa04514
Endothelial,cells(Good)_source	CDH1_ligand	Chondrocytes(Good)_target	CDH1_receptor	3.292e-08	0.03	CDH	Cell-Cell Contact	KEGG: hsa04514
Endothelial,cells(Nos)_source	CDH1_ligand	Chondrocytes(Good)_target	CDH1_receptor	1.207e-06	0.0	CDH	Cell-Cell Contact	KEGG: hsa04514
Neurons(Nos)_source	CDH1_ligand	Chondrocytes(Good)_target	CDH1_receptor	7.414e-07	0.0	CDH	Cell-Cell Contact	KEGG: hsa04514
Adipocytes(Good)_source	CDH1_ligand	Chondrocytes(Nos)_target	CDH1_receptor	2.660e-07	0.0	CDH	Cell-Cell Contact	KEGG: hsa04514
Adipocytes(Nos)_source	CDH1_ligand	Chondrocytes(Nos)_target	CDH1_receptor	4.016e-06	0.0	CDH	Cell-Cell Contact	KEGG: hsa04514
Chondrocytes(Good)_source	CDH1_ligand	Chondrocytes(Nos)_target	CDH1_receptor	7.726e-06	0.0	CDH	Cell-Cell Contact	KEGG: hsa04514
Chondrocytes(Nos)_source	CDH1_ligand	Chondrocytes(Nos)_target	CDH1_receptor	1.065e-04	0.0	CDH	Cell-Cell Contact	KEGG: hsa04514
Endothelial,cells(Good)_source	CDH1_ligand	Chondrocytes(Nos)_target	CDH1_receptor	4.513e-07	0.0	CDH	Cell-Cell Contact	KEGG: hsa04514
Endothelial,cells(Nos)_source	CDH1_ligand	Chondrocytes(Nos)_target	CDH1_receptor	1.654e-05	0.0	CDH	Cell-Cell Contact	KEGG: hsa04514
Neurons(Good)_source	CDH1_ligand	Chondrocytes(Nos)_target	CDH1_receptor	2.134e-07	0.01	CDH	Cell-Cell Contact	KEGG: hsa04514
Neurons(Nos)_source	CDH1_ligand	Chondrocytes(Nos)_target	CDH1_receptor	1.016e-05	0.0	CDH	Cell-Cell Contact	KEGG: hsa04514
Chondrocytes(Good)_source	CDH1_ligand	Endothelial,cells(Good)_target	CDH1_receptor	3.292e-08	0.03	CDH	Cell-Cell Contact	KEGG: hsa04514
Chondrocytes(Nos)_source	CDH1_ligand	Endothelial,cells(Good)_target	CDH1_receptor	4.513e-07	0.0	CDH	Cell-Cell Contact	KEGG: hsa04514
Chondrocytes(Good)_source	CDH1_ligand	Endothelial,cells(Nos)_target	CDH1_receptor	1.207e-06	0.0	CDH	Cell-Cell Contact	KEGG: hsa04514
Chondrocytes(Nos)_source	CDH1_ligand	Endothelial,cells(Nos)_target	CDH1_receptor	1.654e-05	0.0	CDH	Cell-Cell Contact	KEGG: hsa04514
Endothelial,cells(Nos)_source	CDH1_ligand	Endothelial,cells(Nos)_target	CDH1_receptor	2.458e-06	0.0	CDH	Cell-Cell Contact	KEGG: hsa04514
Neurons(Nos)_source	CDH1_ligand	Endothelial,cells(Nos)_target	CDH1_receptor	1.511e-06	0.0	CDH	Cell-Cell Contact	KEGG: hsa04514
Chondrocytes(Nos)_source	CDH1_ligand	Neurons(Good)_target	CDH1_receptor	2.134e-07	0.01	CDH	Cell-Cell Contact	KEGG: hsa04514
Chondrocytes(Good)_source	CDH1_ligand	Neurons(Nos)_target	CDH1_receptor	7.414e-07	0.0	CDH	Cell-Cell Contact	KEGG: hsa04514
Chondrocytes(Nos)_source	CDH1_ligand	Neurons(Nos)_target	CDH1_receptor	1.016e-05	0.0	CDH	Cell-Cell Contact	KEGG: hsa04514
Endothelial,cells(Nos)_source	CDH1_ligand	Neurons(Nos)_target	CDH1_receptor	1.511e-06	0.0	CDH	Cell-Cell Contact	KEGG: hsa04514