Sample overview
| Project Name | TCGA-BRCA |
| GSE ID | GSE182694 |
| GSM ID | GSM5534774 |
| Cell Line | MDAMB436 |
| Tissue type | None |
| Disease Type | Triple-negative Breast Cancer |
| PMID | \ |
| Initial gene number | 33538 |
| Initial cell number | 4521 |
| Post-QC gene number | 7758 |
| Post-QC cell number | 4381 |
QC Metrics
Bulk-to-ScRNA-seq Label Transfer
Bulk phenotype-associated subpopulations
Reference-Based Annotation
Differentially expressed genes
Overall Survival : Cluster vs
There are no results of the analysis here
Overall Survival : Cluster vs ( + )
There are no results of the analysis here
Clinical Stage : Cluster vs
There are no results of the analysis here
Tumor Size : Cluster vs
There are no results of the analysis here
Lymph Node Involvement : Cluster vs
There are no results of the analysis here
Distant Metastasis : Cluster vs
There are no results of the analysis here
Cell-Cell communications ( Survival-Associated Subpopulations Across Cell Types )
Cell Population Signaling and Communication
Ligand-Receptor-Mediated Cell-Cell Interactions
| Sending Cell Type | Ligand | Receiving Cell Type | Receptor | Score | P-value | Pathway Name | Function | Evidence |
|---|---|---|---|---|---|---|---|---|
| Epithelial,cells(Good)_source | FGF2_ligand | Keratinocytes(Nos)_target | FGFR1_receptor | 5.345e-05 | 0.0 | FGF | Secreted Signaling | PMC: 4393358 |
| Epithelial,cells(Nos)_source | FGF2_ligand | Keratinocytes(Nos)_target | FGFR1_receptor | 2.715e-04 | 0.0 | FGF | Secreted Signaling | PMC: 4393358 |
| Keratinocytes(Good)_source | FGF2_ligand | Keratinocytes(Nos)_target | FGFR1_receptor | 2.476e-05 | 0.0 | FGF | Secreted Signaling | PMC: 4393358 |
| Keratinocytes(Nos)_source | FGF2_ligand | Keratinocytes(Nos)_target | FGFR1_receptor | 2.009e-04 | 0.0 | FGF | Secreted Signaling | PMC: 4393358 |
| Epithelial,cells(Good)_source | TNFSF12_ligand | Epithelial,cells(Good)_target | TNFRSF12A_receptor | 4.012e-05 | 0.03 | TWEAK | Secreted Signaling | KEGG: hsa04060 |
| Epithelial,cells(Good)_source | TNFSF12_ligand | Epithelial,cells(Nos)_target | TNFRSF12A_receptor | 2.190e-04 | 0.0 | TWEAK | Secreted Signaling | KEGG: hsa04060 |
| Epithelial,cells(Nos)_source | TNFSF12_ligand | Epithelial,cells(Nos)_target | TNFRSF12A_receptor | 8.670e-04 | 0.01 | TWEAK | Secreted Signaling | KEGG: hsa04060 |
| Epithelial,cells(Good)_source | TNFSF12_ligand | HSC(Good)_target | TNFRSF12A_receptor | 2.385e-05 | 0.0 | TWEAK | Secreted Signaling | KEGG: hsa04060 |
| Epithelial,cells(Nos)_source | TNFSF12_ligand | HSC(Good)_target | TNFRSF12A_receptor | 9.449e-05 | 0.0 | TWEAK | Secreted Signaling | KEGG: hsa04060 |
| Keratinocytes(Nos)_source | TNFSF12_ligand | HSC(Good)_target | TNFRSF12A_receptor | 5.555e-05 | 0.04 | TWEAK | Secreted Signaling | KEGG: hsa04060 |
| Epithelial,cells(Good)_source | TNFSF12_ligand | HSC(Nos)_target | TNFRSF12A_receptor | 4.038e-05 | 0.0 | TWEAK | Secreted Signaling | KEGG: hsa04060 |
| Epithelial,cells(Nos)_source | TNFSF12_ligand | HSC(Nos)_target | TNFRSF12A_receptor | 1.600e-04 | 0.0 | TWEAK | Secreted Signaling | KEGG: hsa04060 |
| Keratinocytes(Nos)_source | TNFSF12_ligand | HSC(Nos)_target | TNFRSF12A_receptor | 9.406e-05 | 0.0 | TWEAK | Secreted Signaling | KEGG: hsa04060 |
| Epithelial,cells(Good)_source | TNFSF12_ligand | Keratinocytes(Good)_target | TNFRSF12A_receptor | 2.112e-05 | 0.0 | TWEAK | Secreted Signaling | KEGG: hsa04060 |
| Epithelial,cells(Nos)_source | TNFSF12_ligand | Keratinocytes(Good)_target | TNFRSF12A_receptor | 8.363e-05 | 0.01 | TWEAK | Secreted Signaling | KEGG: hsa04060 |
| Epithelial,cells(Good)_source | TNFSF12_ligand | Keratinocytes(Nos)_target | TNFRSF12A_receptor | 1.676e-04 | 0.0 | TWEAK | Secreted Signaling | KEGG: hsa04060 |
| Epithelial,cells(Nos)_source | TNFSF12_ligand | Keratinocytes(Nos)_target | TNFRSF12A_receptor | 6.636e-04 | 0.01 | TWEAK | Secreted Signaling | KEGG: hsa04060 |
| Epithelial,cells(Good)_source | MDK_ligand | Keratinocytes(Nos)_target | SDC1_receptor | 1.310e-04 | 0.0 | MK | Secreted Signaling | PMID: 28356350 |
| Epithelial,cells(Nos)_source | MDK_ligand | Keratinocytes(Nos)_target | SDC1_receptor | 7.252e-04 | 0.0 | MK | Secreted Signaling | PMID: 28356350 |
| HSC(Good)_source | MDK_ligand | Keratinocytes(Nos)_target | SDC1_receptor | 4.861e-05 | 0.01 | MK | Secreted Signaling | PMID: 28356350 |
| HSC(Nos)_source | MDK_ligand | Keratinocytes(Nos)_target | SDC1_receptor | 9.580e-05 | 0.0 | MK | Secreted Signaling | PMID: 28356350 |
| Keratinocytes(Good)_source | MDK_ligand | Keratinocytes(Nos)_target | SDC1_receptor | 6.431e-05 | 0.0 | MK | Secreted Signaling | PMID: 28356350 |
| Keratinocytes(Nos)_source | MDK_ligand | Keratinocytes(Nos)_target | SDC1_receptor | 4.746e-04 | 0.0 | MK | Secreted Signaling | PMID: 28356350 |
| Epithelial,cells(Good)_source | MDK_ligand | Epithelial,cells(Nos)_target | SDC4_receptor | 3.358e-04 | 0.03 | MK | Secreted Signaling | PMID: 28356350 |
| Epithelial,cells(Nos)_source | MDK_ligand | Epithelial,cells(Nos)_target | SDC4_receptor | 1.859e-03 | 0.0 | MK | Secreted Signaling | PMID: 28356350 |
| HSC(Nos)_source | MDK_ligand | Epithelial,cells(Nos)_target | SDC4_receptor | 2.455e-04 | 0.0 | MK | Secreted Signaling | PMID: 28356350 |
| Epithelial,cells(Nos)_source | MDK_ligand | Epithelial,cells(Nos)_target | ITGA6_ITGB1_receptor | 2.644e-03 | 0.0 | MK | Secreted Signaling | PMID: 28356350 |
| HSC(Nos)_source | MDK_ligand | Epithelial,cells(Nos)_target | ITGA6_ITGB1_receptor | 3.492e-04 | 0.0 | MK | Secreted Signaling | PMID: 28356350 |
| Epithelial,cells(Good)_source | MDK_ligand | Keratinocytes(Nos)_target | ITGA6_ITGB1_receptor | 3.984e-04 | 0.03 | MK | Secreted Signaling | PMID: 28356350 |
| Epithelial,cells(Nos)_source | MDK_ligand | Keratinocytes(Nos)_target | ITGA6_ITGB1_receptor | 2.204e-03 | 0.0 | MK | Secreted Signaling | PMID: 28356350 |
| HSC(Nos)_source | MDK_ligand | Keratinocytes(Nos)_target | ITGA6_ITGB1_receptor | 2.910e-04 | 0.0 | MK | Secreted Signaling | PMID: 28356350 |
| Epithelial,cells(Good)_source | MDK_ligand | Epithelial,cells(Nos)_target | LRP1_receptor | 3.980e-05 | 0.03 | MK | Secreted Signaling | PMID: 28356350 |
| Epithelial,cells(Nos)_source | MDK_ligand | Epithelial,cells(Nos)_target | LRP1_receptor | 2.204e-04 | 0.0 | MK | Secreted Signaling | PMID: 28356350 |
| HSC(Nos)_source | MDK_ligand | Epithelial,cells(Nos)_target | LRP1_receptor | 2.912e-05 | 0.0 | MK | Secreted Signaling | PMID: 28356350 |
| Keratinocytes(Good)_source | MDK_ligand | Epithelial,cells(Nos)_target | LRP1_receptor | 1.954e-05 | 0.02 | MK | Secreted Signaling | PMID: 28356350 |
| Epithelial,cells(Nos)_source | MDK_ligand | Epithelial,cells(Good)_target | NCL_receptor | 1.823e-03 | 0.01 | MK | Secreted Signaling | PMID: 28356350 |
| Epithelial,cells(Nos)_source | MDK_ligand | Epithelial,cells(Nos)_target | NCL_receptor | 9.566e-03 | 0.0 | MK | Secreted Signaling | PMID: 28356350 |
| HSC(Nos)_source | MDK_ligand | Epithelial,cells(Nos)_target | NCL_receptor | 1.262e-03 | 0.04 | MK | Secreted Signaling | PMID: 28356350 |
| Epithelial,cells(Nos)_source | MDK_ligand | Keratinocytes(Good)_target | NCL_receptor | 8.805e-04 | 0.01 | MK | Secreted Signaling | PMID: 28356350 |
| Epithelial,cells(Nos)_source | MDK_ligand | Keratinocytes(Nos)_target | NCL_receptor | 7.464e-03 | 0.0 | MK | Secreted Signaling | PMID: 28356350 |
| HSC(Nos)_source | MDK_ligand | Keratinocytes(Nos)_target | NCL_receptor | 9.849e-04 | 0.04 | MK | Secreted Signaling | PMID: 28356350 |
| HSC(Good)_source | GAS6_ligand | Epithelial,cells(Good)_target | AXL_receptor | 1.591e-06 | 0.03 | GAS | Secreted Signaling | PMID: 27801848 |
| HSC(Nos)_source | GAS6_ligand | Epithelial,cells(Good)_target | AXL_receptor | 4.164e-06 | 0.0 | GAS | Secreted Signaling | PMID: 27801848 |
| HSC(Good)_source | GAS6_ligand | Epithelial,cells(Nos)_target | AXL_receptor | 1.005e-05 | 0.03 | GAS | Secreted Signaling | PMID: 27801848 |
| HSC(Nos)_source | GAS6_ligand | Epithelial,cells(Nos)_target | AXL_receptor | 2.629e-05 | 0.0 | GAS | Secreted Signaling | PMID: 27801848 |
| HSC(Good)_source | GAS6_ligand | HSC(Nos)_target | AXL_receptor | 1.252e-06 | 0.04 | GAS | Secreted Signaling | PMID: 27801848 |
| HSC(Nos)_source | GAS6_ligand | HSC(Nos)_target | AXL_receptor | 3.277e-06 | 0.01 | GAS | Secreted Signaling | PMID: 27801848 |
| HSC(Good)_source | GAS6_ligand | Keratinocytes(Good)_target | AXL_receptor | 8.800e-07 | 0.03 | GAS | Secreted Signaling | PMID: 27801848 |
| HSC(Nos)_source | GAS6_ligand | Keratinocytes(Good)_target | AXL_receptor | 2.303e-06 | 0.0 | GAS | Secreted Signaling | PMID: 27801848 |
| HSC(Good)_source | GAS6_ligand | Keratinocytes(Nos)_target | AXL_receptor | 7.546e-06 | 0.03 | GAS | Secreted Signaling | PMID: 27801848 |
| HSC(Nos)_source | GAS6_ligand | Keratinocytes(Nos)_target | AXL_receptor | 1.974e-05 | 0.0 | GAS | Secreted Signaling | PMID: 27801848 |
| HSC(Good)_source | GRN_ligand | Epithelial,cells(Good)_target | SORT1_receptor | 6.305e-07 | 0.0 | GRN | Secreted Signaling | PMID: 29555433 |
| HSC(Nos)_source | GRN_ligand | Epithelial,cells(Good)_target | SORT1_receptor | 1.028e-06 | 0.0 | GRN | Secreted Signaling | PMID: 29555433 |
| Epithelial,cells(Good)_source | GRN_ligand | Epithelial,cells(Nos)_target | SORT1_receptor | 6.334e-06 | 0.0 | GRN | Secreted Signaling | PMID: 29555433 |
| HSC(Good)_source | GRN_ligand | Epithelial,cells(Nos)_target | SORT1_receptor | 3.234e-06 | 0.0 | GRN | Secreted Signaling | PMID: 29555433 |
| HSC(Nos)_source | GRN_ligand | Epithelial,cells(Nos)_target | SORT1_receptor | 5.273e-06 | 0.0 | GRN | Secreted Signaling | PMID: 29555433 |
| HSC(Good)_source | GRN_ligand | Keratinocytes(Good)_target | SORT1_receptor | 2.832e-07 | 0.02 | GRN | Secreted Signaling | PMID: 29555433 |
| HSC(Nos)_source | GRN_ligand | Keratinocytes(Good)_target | SORT1_receptor | 4.618e-07 | 0.01 | GRN | Secreted Signaling | PMID: 29555433 |
| Epithelial,cells(Good)_source | GRN_ligand | Keratinocytes(Nos)_target | SORT1_receptor | 5.078e-06 | 0.0 | GRN | Secreted Signaling | PMID: 29555433 |
| Epithelial,cells(Nos)_source | GRN_ligand | Keratinocytes(Nos)_target | SORT1_receptor | 2.375e-05 | 0.0 | GRN | Secreted Signaling | PMID: 29555433 |
| HSC(Good)_source | GRN_ligand | Keratinocytes(Nos)_target | SORT1_receptor | 2.593e-06 | 0.0 | GRN | Secreted Signaling | PMID: 29555433 |
| HSC(Nos)_source | GRN_ligand | Keratinocytes(Nos)_target | SORT1_receptor | 4.228e-06 | 0.0 | GRN | Secreted Signaling | PMID: 29555433 |
| HSC(Good)_source | COL6A2_ligand | Epithelial,cells(Good)_target | ITGA2_ITGB1_receptor | 8.262e-06 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| HSC(Nos)_source | COL6A2_ligand | Epithelial,cells(Good)_target | ITGA2_ITGB1_receptor | 8.804e-06 | 0.02 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| HSC(Good)_source | COL6A2_ligand | Epithelial,cells(Nos)_target | ITGA2_ITGB1_receptor | 4.088e-05 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| HSC(Nos)_source | COL6A2_ligand | Epithelial,cells(Nos)_target | ITGA2_ITGB1_receptor | 4.355e-05 | 0.03 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| HSC(Good)_source | COL6A2_ligand | HSC(Good)_target | ITGA2_ITGB1_receptor | 5.685e-07 | 0.01 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| HSC(Good)_source | COL6A2_ligand | HSC(Nos)_target | ITGA2_ITGB1_receptor | 1.151e-06 | 0.01 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| HSC(Nos)_source | COL6A2_ligand | HSC(Nos)_target | ITGA2_ITGB1_receptor | 1.226e-06 | 0.04 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| HSC(Good)_source | COL6A2_ligand | Keratinocytes(Good)_target | ITGA2_ITGB1_receptor | 3.718e-06 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| HSC(Nos)_source | COL6A2_ligand | Keratinocytes(Good)_target | ITGA2_ITGB1_receptor | 3.962e-06 | 0.03 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| HSC(Good)_source | COL6A2_ligand | Keratinocytes(Nos)_target | ITGA2_ITGB1_receptor | 3.209e-05 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| HSC(Nos)_source | COL6A2_ligand | Keratinocytes(Nos)_target | ITGA2_ITGB1_receptor | 3.419e-05 | 0.02 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| HSC(Good)_source | LAMB3_ligand | Epithelial,cells(Good)_target | ITGA2_ITGB1_receptor | 1.223e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| HSC(Nos)_source | LAMB3_ligand | Epithelial,cells(Good)_target | ITGA2_ITGB1_receptor | 1.582e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| HSC(Good)_source | LAMB3_ligand | Epithelial,cells(Nos)_target | ITGA2_ITGB1_receptor | 6.051e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| HSC(Nos)_source | LAMB3_ligand | Epithelial,cells(Nos)_target | ITGA2_ITGB1_receptor | 7.825e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| HSC(Good)_source | LAMB3_ligand | HSC(Good)_target | ITGA2_ITGB1_receptor | 8.423e-07 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| HSC(Nos)_source | LAMB3_ligand | HSC(Good)_target | ITGA2_ITGB1_receptor | 1.089e-06 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| HSC(Good)_source | LAMB3_ligand | HSC(Nos)_target | ITGA2_ITGB1_receptor | 1.706e-06 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| HSC(Nos)_source | LAMB3_ligand | HSC(Nos)_target | ITGA2_ITGB1_receptor | 2.205e-06 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| HSC(Good)_source | LAMB3_ligand | Keratinocytes(Good)_target | ITGA2_ITGB1_receptor | 5.504e-06 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| HSC(Nos)_source | LAMB3_ligand | Keratinocytes(Good)_target | ITGA2_ITGB1_receptor | 7.118e-06 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| HSC(Good)_source | LAMB3_ligand | Keratinocytes(Nos)_target | ITGA2_ITGB1_receptor | 4.749e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| HSC(Nos)_source | LAMB3_ligand | Keratinocytes(Nos)_target | ITGA2_ITGB1_receptor | 6.142e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Keratinocytes(Nos)_source | LAMC1_ligand | Epithelial,cells(Good)_target | ITGA2_ITGB1_receptor | 8.679e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Keratinocytes(Nos)_source | LAMC1_ligand | Epithelial,cells(Nos)_target | ITGA2_ITGB1_receptor | 4.294e-04 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Keratinocytes(Nos)_source | LAMC1_ligand | Keratinocytes(Good)_target | ITGA2_ITGB1_receptor | 3.906e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Keratinocytes(Nos)_source | LAMC1_ligand | Keratinocytes(Nos)_target | ITGA2_ITGB1_receptor | 3.371e-04 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| HSC(Good)_source | LAMB3_ligand | Epithelial,cells(Good)_target | ITGA3_ITGB1_receptor | 9.149e-06 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| HSC(Nos)_source | LAMB3_ligand | Epithelial,cells(Good)_target | ITGA3_ITGB1_receptor | 1.183e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| HSC(Good)_source | LAMB3_ligand | Epithelial,cells(Nos)_target | ITGA3_ITGB1_receptor | 4.680e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| HSC(Nos)_source | LAMB3_ligand | Epithelial,cells(Nos)_target | ITGA3_ITGB1_receptor | 6.052e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| HSC(Good)_source | LAMB3_ligand | Keratinocytes(Good)_target | ITGA3_ITGB1_receptor | 4.448e-06 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| HSC(Nos)_source | LAMB3_ligand | Keratinocytes(Good)_target | ITGA3_ITGB1_receptor | 5.752e-06 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| HSC(Good)_source | LAMB3_ligand | Keratinocytes(Nos)_target | ITGA3_ITGB1_receptor | 3.739e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| HSC(Nos)_source | LAMB3_ligand | Keratinocytes(Nos)_target | ITGA3_ITGB1_receptor | 4.835e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Keratinocytes(Nos)_source | LAMC1_ligand | Epithelial,cells(Good)_target | ITGA3_ITGB1_receptor | 6.491e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Keratinocytes(Nos)_source | LAMC1_ligand | Epithelial,cells(Nos)_target | ITGA3_ITGB1_receptor | 3.321e-04 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Keratinocytes(Nos)_source | LAMC1_ligand | Keratinocytes(Good)_target | ITGA3_ITGB1_receptor | 3.156e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Keratinocytes(Nos)_source | LAMC1_ligand | Keratinocytes(Nos)_target | ITGA3_ITGB1_receptor | 2.653e-04 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| HSC(Good)_source | COL6A2_ligand | Epithelial,cells(Good)_target | ITGA3_ITGB1_receptor | 6.179e-06 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| HSC(Nos)_source | COL6A2_ligand | Epithelial,cells(Good)_target | ITGA3_ITGB1_receptor | 6.582e-06 | 0.03 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| HSC(Good)_source | COL6A2_ligand | Epithelial,cells(Nos)_target | ITGA3_ITGB1_receptor | 3.161e-05 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| HSC(Nos)_source | COL6A2_ligand | Epithelial,cells(Nos)_target | ITGA3_ITGB1_receptor | 3.368e-05 | 0.03 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| HSC(Good)_source | COL6A2_ligand | Keratinocytes(Good)_target | ITGA3_ITGB1_receptor | 3.004e-06 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| HSC(Nos)_source | COL6A2_ligand | Keratinocytes(Good)_target | ITGA3_ITGB1_receptor | 3.200e-06 | 0.03 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| HSC(Good)_source | COL6A2_ligand | Keratinocytes(Nos)_target | ITGA3_ITGB1_receptor | 2.525e-05 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| HSC(Nos)_source | COL6A2_ligand | Keratinocytes(Nos)_target | ITGA3_ITGB1_receptor | 2.691e-05 | 0.03 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| HSC(Good)_source | LAMB3_ligand | Epithelial,cells(Good)_target | ITGA6_ITGB1_receptor | 7.579e-06 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| HSC(Nos)_source | LAMB3_ligand | Epithelial,cells(Good)_target | ITGA6_ITGB1_receptor | 9.800e-06 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| HSC(Good)_source | LAMB3_ligand | Epithelial,cells(Nos)_target | ITGA6_ITGB1_receptor | 3.887e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| HSC(Nos)_source | LAMB3_ligand | Epithelial,cells(Nos)_target | ITGA6_ITGB1_receptor | 5.026e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| HSC(Good)_source | LAMB3_ligand | HSC(Good)_target | ITGA6_ITGB1_receptor | 6.225e-07 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| HSC(Nos)_source | LAMB3_ligand | HSC(Good)_target | ITGA6_ITGB1_receptor | 8.046e-07 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| HSC(Good)_source | LAMB3_ligand | HSC(Nos)_target | ITGA6_ITGB1_receptor | 1.207e-06 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| HSC(Nos)_source | LAMB3_ligand | HSC(Nos)_target | ITGA6_ITGB1_receptor | 1.560e-06 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| HSC(Good)_source | LAMB3_ligand | Keratinocytes(Good)_target | ITGA6_ITGB1_receptor | 3.744e-06 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| HSC(Nos)_source | LAMB3_ligand | Keratinocytes(Good)_target | ITGA6_ITGB1_receptor | 4.841e-06 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| HSC(Good)_source | LAMB3_ligand | Keratinocytes(Nos)_target | ITGA6_ITGB1_receptor | 3.243e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| HSC(Nos)_source | LAMB3_ligand | Keratinocytes(Nos)_target | ITGA6_ITGB1_receptor | 4.193e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Keratinocytes(Nos)_source | LAMC1_ligand | Epithelial,cells(Good)_target | ITGA6_ITGB1_receptor | 5.377e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Keratinocytes(Nos)_source | LAMC1_ligand | Epithelial,cells(Nos)_target | ITGA6_ITGB1_receptor | 2.758e-04 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Keratinocytes(Nos)_source | LAMC1_ligand | Keratinocytes(Good)_target | ITGA6_ITGB1_receptor | 2.656e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Keratinocytes(Nos)_source | LAMC1_ligand | Keratinocytes(Nos)_target | ITGA6_ITGB1_receptor | 2.301e-04 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| HSC(Good)_source | COL6A2_ligand | Epithelial,cells(Good)_target | CD44_receptor | 1.187e-05 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| HSC(Nos)_source | COL6A2_ligand | Epithelial,cells(Good)_target | CD44_receptor | 1.265e-05 | 0.03 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| HSC(Good)_source | COL6A2_ligand | Epithelial,cells(Nos)_target | CD44_receptor | 6.511e-05 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| HSC(Nos)_source | COL6A2_ligand | Epithelial,cells(Nos)_target | CD44_receptor | 6.941e-05 | 0.03 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| HSC(Good)_source | COL6A2_ligand | HSC(Good)_target | CD44_receptor | 4.480e-06 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| HSC(Nos)_source | COL6A2_ligand | HSC(Good)_target | CD44_receptor | 4.774e-06 | 0.03 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| HSC(Good)_source | COL6A2_ligand | HSC(Nos)_target | CD44_receptor | 6.486e-06 | 0.01 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| HSC(Nos)_source | COL6A2_ligand | HSC(Nos)_target | CD44_receptor | 6.912e-06 | 0.03 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| HSC(Good)_source | COL6A2_ligand | Keratinocytes(Good)_target | CD44_receptor | 4.298e-06 | 0.01 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| HSC(Nos)_source | COL6A2_ligand | Keratinocytes(Good)_target | CD44_receptor | 4.580e-06 | 0.04 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| HSC(Good)_source | COL6A2_ligand | Keratinocytes(Nos)_target | CD44_receptor | 3.880e-05 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| HSC(Nos)_source | COL6A2_ligand | Keratinocytes(Nos)_target | CD44_receptor | 4.135e-05 | 0.04 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| HSC(Good)_source | LAMB3_ligand | Epithelial,cells(Good)_target | CD44_receptor | 1.756e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| HSC(Nos)_source | LAMB3_ligand | Epithelial,cells(Good)_target | CD44_receptor | 2.271e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| HSC(Good)_source | LAMB3_ligand | Epithelial,cells(Nos)_target | CD44_receptor | 9.631e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| HSC(Nos)_source | LAMB3_ligand | Epithelial,cells(Nos)_target | CD44_receptor | 1.246e-04 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| HSC(Good)_source | LAMB3_ligand | HSC(Good)_target | CD44_receptor | 6.628e-06 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| HSC(Nos)_source | LAMB3_ligand | HSC(Good)_target | CD44_receptor | 8.574e-06 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| HSC(Good)_source | LAMB3_ligand | HSC(Nos)_target | CD44_receptor | 9.598e-06 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| HSC(Nos)_source | LAMB3_ligand | HSC(Nos)_target | CD44_receptor | 1.241e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| HSC(Good)_source | LAMB3_ligand | Keratinocytes(Good)_target | CD44_receptor | 6.361e-06 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| HSC(Nos)_source | LAMB3_ligand | Keratinocytes(Good)_target | CD44_receptor | 8.228e-06 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| HSC(Good)_source | LAMB3_ligand | Keratinocytes(Nos)_target | CD44_receptor | 5.741e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| HSC(Nos)_source | LAMB3_ligand | Keratinocytes(Nos)_target | CD44_receptor | 7.426e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Keratinocytes(Nos)_source | LAMC1_ligand | Epithelial,cells(Good)_target | CD44_receptor | 1.247e-04 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Keratinocytes(Nos)_source | LAMC1_ligand | Epithelial,cells(Nos)_target | CD44_receptor | 6.839e-04 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Keratinocytes(Nos)_source | LAMC1_ligand | HSC(Good)_target | CD44_receptor | 4.705e-05 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Keratinocytes(Nos)_source | LAMC1_ligand | HSC(Nos)_target | CD44_receptor | 6.813e-05 | 0.01 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Keratinocytes(Nos)_source | LAMC1_ligand | Keratinocytes(Good)_target | CD44_receptor | 4.515e-05 | 0.01 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| Keratinocytes(Nos)_source | LAMC1_ligand | Keratinocytes(Nos)_target | CD44_receptor | 4.075e-04 | 0.0 | LAMININ | ECM-Receptor | KEGG: hsa04512 |
| HSC(Good)_source | COL6A2_ligand | Keratinocytes(Nos)_target | SDC1_receptor | 7.143e-06 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| HSC(Nos)_source | COL6A2_ligand | Keratinocytes(Nos)_target | SDC1_receptor | 7.606e-06 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| HSC(Good)_source | COL6A2_ligand | Epithelial,cells(Good)_target | SDC4_receptor | 3.251e-06 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| HSC(Nos)_source | COL6A2_ligand | Epithelial,cells(Good)_target | SDC4_receptor | 3.463e-06 | 0.04 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| HSC(Good)_source | COL6A2_ligand | Epithelial,cells(Nos)_target | SDC4_receptor | 1.839e-05 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| HSC(Nos)_source | COL6A2_ligand | Epithelial,cells(Nos)_target | SDC4_receptor | 1.958e-05 | 0.02 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| HSC(Good)_source | COL6A2_ligand | HSC(Nos)_target | SDC4_receptor | 1.657e-06 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| HSC(Nos)_source | COL6A2_ligand | HSC(Nos)_target | SDC4_receptor | 1.765e-06 | 0.04 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| HSC(Good)_source | COL6A2_ligand | Keratinocytes(Good)_target | SDC4_receptor | 1.111e-06 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| HSC(Nos)_source | COL6A2_ligand | Keratinocytes(Good)_target | SDC4_receptor | 1.183e-06 | 0.04 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| HSC(Good)_source | COL6A2_ligand | Keratinocytes(Nos)_target | SDC4_receptor | 1.186e-05 | 0.0 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| HSC(Nos)_source | COL6A2_ligand | Keratinocytes(Nos)_target | SDC4_receptor | 1.263e-05 | 0.03 | COLLAGEN | ECM-Receptor | KEGG: hsa04512 |
| Keratinocytes(Good)_source | ADGRE5_ligand | HSC(Good)_target | CD55_receptor | 1.162e-06 | 0.01 | ADGRE5 | Cell-Cell Contact | PMID: 11297558 |
| Keratinocytes(Nos)_source | ADGRE5_ligand | HSC(Good)_target | CD55_receptor | 9.602e-06 | 0.0 | ADGRE5 | Cell-Cell Contact | PMID: 11297558 |
| Keratinocytes(Good)_source | ADGRE5_ligand | HSC(Nos)_target | CD55_receptor | 1.552e-06 | 0.01 | ADGRE5 | Cell-Cell Contact | PMID: 11297558 |
| Keratinocytes(Nos)_source | ADGRE5_ligand | HSC(Nos)_target | CD55_receptor | 1.283e-05 | 0.0 | ADGRE5 | Cell-Cell Contact | PMID: 11297558 |
| Epithelial,cells(Nos)_source | CD99_ligand | Epithelial,cells(Nos)_target | CD99_receptor | 4.605e-03 | 0.0 | CD99 | Cell-Cell Contact | KEGG: hsa04514 |
| Keratinocytes(Nos)_source | CD99_ligand | Epithelial,cells(Nos)_target | CD99_receptor | 3.309e-03 | 0.0 | CD99 | Cell-Cell Contact | KEGG: hsa04514 |
| Epithelial,cells(Nos)_source | CD99_ligand | Keratinocytes(Nos)_target | CD99_receptor | 3.309e-03 | 0.0 | CD99 | Cell-Cell Contact | KEGG: hsa04514 |
| Epithelial,cells(Nos)_source | CDH2_ligand | Epithelial,cells(Nos)_target | CDH2_receptor | 8.701e-05 | 0.0 | CDH | Cell-Cell Contact | KEGG: hsa04514 |
| Keratinocytes(Nos)_source | CDH2_ligand | Epithelial,cells(Nos)_target | CDH2_receptor | 6.807e-05 | 0.0 | CDH | Cell-Cell Contact | KEGG: hsa04514 |
| Epithelial,cells(Nos)_source | CDH2_ligand | Keratinocytes(Nos)_target | CDH2_receptor | 6.807e-05 | 0.0 | CDH | Cell-Cell Contact | KEGG: hsa04514 |
| Keratinocytes(Nos)_source | CDH2_ligand | Keratinocytes(Nos)_target | CDH2_receptor | 5.326e-05 | 0.0 | CDH | Cell-Cell Contact | KEGG: hsa04514 |
| HSC(Good)_source | EFNA1_ligand | Epithelial,cells(Good)_target | EPHA2_receptor | 8.093e-07 | 0.0 | EPHA | Cell-Cell Contact | PMID: 15114347 |
| HSC(Nos)_source | EFNA1_ligand | Epithelial,cells(Good)_target | EPHA2_receptor | 1.695e-06 | 0.0 | EPHA | Cell-Cell Contact | PMID: 15114347 |
| HSC(Good)_source | EFNA1_ligand | Epithelial,cells(Nos)_target | EPHA2_receptor | 4.236e-06 | 0.0 | EPHA | Cell-Cell Contact | PMID: 15114347 |
| HSC(Nos)_source | EFNA1_ligand | Epithelial,cells(Nos)_target | EPHA2_receptor | 8.874e-06 | 0.0 | EPHA | Cell-Cell Contact | PMID: 15114347 |
| HSC(Good)_source | EFNA1_ligand | HSC(Good)_target | EPHA2_receptor | 1.797e-07 | 0.02 | EPHA | Cell-Cell Contact | PMID: 15114347 |
| HSC(Nos)_source | EFNA1_ligand | HSC(Good)_target | EPHA2_receptor | 3.764e-07 | 0.0 | EPHA | Cell-Cell Contact | PMID: 15114347 |
| HSC(Good)_source | EFNA1_ligand | HSC(Nos)_target | EPHA2_receptor | 3.108e-07 | 0.0 | EPHA | Cell-Cell Contact | PMID: 15114347 |
| HSC(Nos)_source | EFNA1_ligand | HSC(Nos)_target | EPHA2_receptor | 6.511e-07 | 0.0 | EPHA | Cell-Cell Contact | PMID: 15114347 |
| HSC(Good)_source | EFNA1_ligand | Keratinocytes(Good)_target | EPHA2_receptor | 3.166e-07 | 0.0 | EPHA | Cell-Cell Contact | PMID: 15114347 |
| HSC(Nos)_source | EFNA1_ligand | Keratinocytes(Good)_target | EPHA2_receptor | 6.632e-07 | 0.0 | EPHA | Cell-Cell Contact | PMID: 15114347 |
| Epithelial,cells(Nos)_source | EFNA1_ligand | Keratinocytes(Nos)_target | EPHA2_receptor | 7.922e-06 | 0.0 | EPHA | Cell-Cell Contact | PMID: 15114347 |
| HSC(Good)_source | EFNA1_ligand | Keratinocytes(Nos)_target | EPHA2_receptor | 4.459e-06 | 0.0 | EPHA | Cell-Cell Contact | PMID: 15114347 |
| HSC(Nos)_source | EFNA1_ligand | Keratinocytes(Nos)_target | EPHA2_receptor | 9.341e-06 | 0.0 | EPHA | Cell-Cell Contact | PMID: 15114347 |
| Keratinocytes(Nos)_source | EFNA1_ligand | Keratinocytes(Nos)_target | EPHA2_receptor | 6.394e-06 | 0.0 | EPHA | Cell-Cell Contact | PMID: 15114347 |
| HSC(Good)_source | EFNA4_ligand | Epithelial,cells(Good)_target | EPHA2_receptor | 2.793e-07 | 0.02 | EPHA | Cell-Cell Contact | PMID: 15114347 |
| HSC(Nos)_source | EFNA4_ligand | Epithelial,cells(Good)_target | EPHA2_receptor | 4.695e-07 | 0.0 | EPHA | Cell-Cell Contact | PMID: 15114347 |
| HSC(Good)_source | EFNA4_ligand | Epithelial,cells(Nos)_target | EPHA2_receptor | 1.462e-06 | 0.02 | EPHA | Cell-Cell Contact | PMID: 15114347 |
| HSC(Nos)_source | EFNA4_ligand | Epithelial,cells(Nos)_target | EPHA2_receptor | 2.457e-06 | 0.0 | EPHA | Cell-Cell Contact | PMID: 15114347 |
| Epithelial,cells(Good)_source | EFNA4_ligand | Keratinocytes(Nos)_target | EPHA2_receptor | 2.117e-06 | 0.04 | EPHA | Cell-Cell Contact | PMID: 15114347 |
| Epithelial,cells(Nos)_source | EFNA4_ligand | Keratinocytes(Nos)_target | EPHA2_receptor | 1.058e-05 | 0.0 | EPHA | Cell-Cell Contact | PMID: 15114347 |
| HSC(Good)_source | EFNA4_ligand | Keratinocytes(Nos)_target | EPHA2_receptor | 1.539e-06 | 0.02 | EPHA | Cell-Cell Contact | PMID: 15114347 |
| HSC(Nos)_source | EFNA4_ligand | Keratinocytes(Nos)_target | EPHA2_receptor | 2.587e-06 | 0.0 | EPHA | Cell-Cell Contact | PMID: 15114347 |
| Keratinocytes(Nos)_source | EFNA4_ligand | Keratinocytes(Nos)_target | EPHA2_receptor | 9.018e-06 | 0.0 | EPHA | Cell-Cell Contact | PMID: 15114347 |
| Epithelial,cells(Nos)_source | L1CAM_ligand | Epithelial,cells(Nos)_target | L1CAM_receptor | 3.234e-08 | 0.0 | L1CAM | Cell-Cell Contact | PMID: 18701456 |
| Keratinocytes(Nos)_source | L1CAM_ligand | Epithelial,cells(Nos)_target | L1CAM_receptor | 2.417e-08 | 0.0 | L1CAM | Cell-Cell Contact | PMID: 18701456 |
| Epithelial,cells(Nos)_source | L1CAM_ligand | Keratinocytes(Nos)_target | L1CAM_receptor | 2.417e-08 | 0.0 | L1CAM | Cell-Cell Contact | PMID: 18701456 |