Sample overview
| Project Name |
TARGET-RT
|
| GSE ID |
GSE174376
|
| GSM ID |
GSM5390490
|
| Cell Line |
None
|
| Tissue type |
None
|
| Disease Type |
Rhabdomyosarcoma
|
| PMID |
35483358
|
| Initial gene number |
112137
|
| Initial cell number |
5136
|
| Post-QC gene number |
8487
|
| Post-QC cell number |
4894
|
Bulk-to-ScRNA-seq Label Transfer
Bulk phenotype-associated subpopulations
Reference-Based Annotation
Differentially expressed genes
Overall Survival : Cluster
vs
There are no results of the analysis here
Overall Survival : Cluster
vs ( + )
There are no results of the analysis here
Clinical Stage : Cluster
vs
There
are no results of the analysis here
Tumor Size : Cluster
vs
There
are no results of the analysis here
Lymph Node Involvement : Cluster
vs
There
are no results of the analysis here
Distant Metastasis : Cluster
vs
There
are no results of the analysis here
Cell-Cell communications ( Survival-Associated Subpopulations Across Cell Types )
Cell Population Signaling and Communication
Ligand-Receptor-Mediated Cell-Cell Interactions
| Sending Cell Type |
Ligand |
Receiving Cell Type |
Receptor |
Score |
P-value |
Pathway Name |
Function |
Evidence |
| Erythrocytes(Nos)_source |
MSTN_ligand |
Erythrocytes(Nos)_target |
TGFBR1_ACVR2B_receptor |
9.870e-05 |
0.0 |
MSTN |
Secreted Signaling |
KEGG: hsa04060 |
| Erythrocytes(Nos)_source |
MSTN_ligand |
HSC(Nos)_target |
TGFBR1_ACVR2B_receptor |
1.006e-04 |
0.0 |
MSTN |
Secreted Signaling |
KEGG: hsa04060 |
| Erythrocytes(Nos)_source |
MSTN_ligand |
Erythrocytes(Nos)_target |
TGFBR1_ACVR2A_receptor |
1.228e-04 |
0.02 |
MSTN |
Secreted Signaling |
KEGG: hsa04060 |
| Erythrocytes(Nos)_source |
FGF7_ligand |
Erythrocytes(Nos)_target |
FGFR2_receptor |
6.479e-05 |
0.01 |
FGF |
Secreted Signaling |
PMC: 4393358 |
| Myocytes(Nos)_source |
FGF7_ligand |
Erythrocytes(Nos)_target |
FGFR2_receptor |
2.436e-05 |
0.0 |
FGF |
Secreted Signaling |
PMC: 4393358 |
| Myocytes(Nos)_source |
FGF7_ligand |
HSC(Nos)_target |
FGFR2_receptor |
2.270e-05 |
0.0 |
FGF |
Secreted Signaling |
PMC: 4393358 |
| Erythrocytes(Nos)_source |
FGF8_ligand |
Erythrocytes(Nos)_target |
FGFR2_receptor |
2.023e-04 |
0.0 |
FGF |
Secreted Signaling |
PMC: 4393358 |
| HSC(Nos)_source |
FGF8_ligand |
Erythrocytes(Nos)_target |
FGFR2_receptor |
1.986e-04 |
0.0 |
FGF |
Secreted Signaling |
PMC: 4393358 |
| Erythrocytes(Nos)_source |
FGF8_ligand |
HSC(Nos)_target |
FGFR2_receptor |
1.885e-04 |
0.01 |
FGF |
Secreted Signaling |
PMC: 4393358 |
| Erythrocytes(Nos)_source |
FGF8_ligand |
Erythrocytes(Nos)_target |
FGFR4_receptor |
2.571e-03 |
0.0 |
FGF |
Secreted Signaling |
PMC: 4393358 |
| HSC(Nos)_source |
FGF8_ligand |
Erythrocytes(Nos)_target |
FGFR4_receptor |
2.526e-03 |
0.0 |
FGF |
Secreted Signaling |
PMC: 4393358 |
| Erythrocytes(Nos)_source |
IGF2_ligand |
Erythrocytes(Nos)_target |
IGF1R_receptor |
1.672e-05 |
0.0 |
IGF |
Secreted Signaling |
PMID: 14604834 |
| HSC(Nos)_source |
IGF2_ligand |
Erythrocytes(Nos)_target |
IGF1R_receptor |
1.577e-05 |
0.0 |
IGF |
Secreted Signaling |
PMID: 14604834 |
| Myocytes(Nos)_source |
IGF2_ligand |
Erythrocytes(Nos)_target |
IGF1R_receptor |
5.143e-06 |
0.0 |
IGF |
Secreted Signaling |
PMID: 14604834 |
| Erythrocytes(Nos)_source |
IGF2_ligand |
Myocytes(Nos)_target |
IGF1R_receptor |
5.268e-06 |
0.0 |
IGF |
Secreted Signaling |
PMID: 14604834 |
| HSC(Nos)_source |
IGF2_ligand |
Myocytes(Nos)_target |
IGF1R_receptor |
4.968e-06 |
0.01 |
IGF |
Secreted Signaling |
PMID: 14604834 |
| Myocytes(Nos)_source |
IGF2_ligand |
Myocytes(Nos)_target |
IGF1R_receptor |
1.620e-06 |
0.0 |
IGF |
Secreted Signaling |
PMID: 14604834 |
| Erythrocytes(Nos)_source |
CXCL12_ligand |
Erythrocytes(Nos)_target |
CXCR4_receptor |
1.179e-03 |
0.0 |
CXCL |
Secreted Signaling |
KEGG: hsa04060 |
| HSC(Nos)_source |
CXCL12_ligand |
Erythrocytes(Nos)_target |
CXCR4_receptor |
8.798e-04 |
0.0 |
CXCL |
Secreted Signaling |
KEGG: hsa04060 |
| Erythrocytes(Nos)_source |
CXCL12_ligand |
HSC(Nos)_target |
CXCR4_receptor |
8.210e-04 |
0.01 |
CXCL |
Secreted Signaling |
KEGG: hsa04060 |
| Erythrocytes(Nos)_source |
MDK_ligand |
Erythrocytes(Nos)_target |
SDC2_receptor |
9.620e-03 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| HSC(Nos)_source |
MDK_ligand |
Erythrocytes(Nos)_target |
SDC2_receptor |
1.070e-02 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| HSC(Nos)_source |
MDK_ligand |
HSC(Nos)_target |
SDC2_receptor |
9.607e-03 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| HSC(Nos)_source |
MDK_ligand |
Erythrocytes(Nos)_target |
ITGA6_ITGB1_receptor |
2.412e-03 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| HSC(Nos)_source |
MDK_ligand |
HSC(Nos)_target |
ITGA6_ITGB1_receptor |
2.578e-03 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| HSC(Nos)_source |
MDK_ligand |
Erythrocytes(Nos)_target |
NCL_receptor |
1.400e-02 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| Erythrocytes(Nos)_source |
MDK_ligand |
HSC(Nos)_target |
NCL_receptor |
1.399e-02 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| HSC(Nos)_source |
MDK_ligand |
HSC(Nos)_target |
NCL_receptor |
1.553e-02 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| Erythrocytes(Nos)_source |
GRN_ligand |
Erythrocytes(Nos)_target |
SORT1_receptor |
9.235e-06 |
0.0 |
GRN |
Secreted Signaling |
PMID: 29555433 |
| HSC(Nos)_source |
GRN_ligand |
Erythrocytes(Nos)_target |
SORT1_receptor |
9.826e-06 |
0.0 |
GRN |
Secreted Signaling |
PMID: 29555433 |
| HSC(Nos)_source |
LAMB3_ligand |
Erythrocytes(Nos)_target |
ITGA6_ITGB1_receptor |
1.039e-03 |
0.0 |
LAMININ |
ECM-Receptor |
KEGG: hsa04512 |
| HSC(Nos)_source |
LAMB3_ligand |
HSC(Nos)_target |
ITGA6_ITGB1_receptor |
1.110e-03 |
0.0 |
LAMININ |
ECM-Receptor |
KEGG: hsa04512 |
| HSC(Nos)_source |
LAMB3_ligand |
Erythrocytes(Nos)_target |
ITGA7_ITGB1_receptor |
1.180e-03 |
0.0 |
LAMININ |
ECM-Receptor |
KEGG: hsa04512 |
| HSC(Nos)_source |
LAMB3_ligand |
HSC(Nos)_target |
ITGA7_ITGB1_receptor |
1.222e-03 |
0.0 |
LAMININ |
ECM-Receptor |
KEGG: hsa04512 |
| Erythrocytes(Nos)_source |
HSPG2_ligand |
HSC(Nos)_target |
DAG1_receptor |
5.012e-05 |
0.0 |
HSPG |
ECM-Receptor |
KEGG: hsa04512 |
| Erythrocytes(Nos)_source |
HSPG2_ligand |
Myocytes(Nos)_target |
DAG1_receptor |
1.286e-05 |
0.03 |
HSPG |
ECM-Receptor |
KEGG: hsa04512 |
| HSC(Nos)_source |
LAMB3_ligand |
Erythrocytes(Nos)_target |
DAG1_receptor |
4.909e-04 |
0.0 |
LAMININ |
ECM-Receptor |
KEGG: hsa04512 |
| HSC(Nos)_source |
LAMB3_ligand |
HSC(Nos)_target |
DAG1_receptor |
6.363e-04 |
0.0 |
LAMININ |
ECM-Receptor |
KEGG: hsa04512 |
| HSC(Nos)_source |
LAMB3_ligand |
Myocytes(Nos)_target |
DAG1_receptor |
1.633e-04 |
0.0 |
LAMININ |
ECM-Receptor |
KEGG: hsa04512 |
| HSC(Nos)_source |
CD99_ligand |
HSC(Nos)_target |
CD99_receptor |
2.811e-03 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Erythrocytes(Nos)_source |
EFNA2_ligand |
Erythrocytes(Nos)_target |
EPHA7_receptor |
1.143e-06 |
0.0 |
EPHA |
Cell-Cell Contact |
PMID: 15114347 |
| Erythrocytes(Nos)_source |
EFNA2_ligand |
HSC(Nos)_target |
EPHA7_receptor |
1.499e-06 |
0.0 |
EPHA |
Cell-Cell Contact |
PMID: 15114347 |
| Erythrocytes(Nos)_source |
EFNA5_ligand |
HSC(Nos)_target |
EPHA7_receptor |
1.236e-06 |
0.0 |
EPHA |
Cell-Cell Contact |
PMID: 15114347 |
| HSC(Nos)_source |
EFNA5_ligand |
HSC(Nos)_target |
EPHA7_receptor |
1.180e-06 |
0.01 |
EPHA |
Cell-Cell Contact |
PMID: 15114347 |
| Erythrocytes(Nos)_source |
EFNA5_ligand |
Erythrocytes(Nos)_target |
EPHB2_receptor |
1.659e-07 |
0.01 |
EPHA |
Cell-Cell Contact |
PMID:15107857; PMID: 15114347 |
| Erythrocytes(Nos)_source |
EFNA5_ligand |
HSC(Nos)_target |
EPHB2_receptor |
1.676e-07 |
0.03 |
EPHA |
Cell-Cell Contact |
PMID:15107857; PMID: 15114347 |
| HSC(Nos)_source |
EFNB2_ligand |
Erythrocytes(Nos)_target |
EPHB2_receptor |
8.917e-07 |
0.0 |
EPHB |
Cell-Cell Contact |
PMID: 15114347 |
| Myocytes(Nos)_source |
EFNB2_ligand |
Erythrocytes(Nos)_target |
EPHB2_receptor |
2.675e-07 |
0.0 |
EPHB |
Cell-Cell Contact |
PMID: 15114347 |
| HSC(Nos)_source |
EFNB2_ligand |
HSC(Nos)_target |
EPHB2_receptor |
9.010e-07 |
0.0 |
EPHB |
Cell-Cell Contact |
PMID: 15114347 |
| Myocytes(Nos)_source |
EFNB2_ligand |
HSC(Nos)_target |
EPHB2_receptor |
2.703e-07 |
0.01 |
EPHB |
Cell-Cell Contact |
PMID: 15114347 |
| HSC(Nos)_source |
EFNB2_ligand |
Myocytes(Nos)_target |
EPHB2_receptor |
2.587e-07 |
0.0 |
EPHB |
Cell-Cell Contact |
PMID: 15114347 |
| Myocytes(Nos)_source |
EFNB2_ligand |
Myocytes(Nos)_target |
EPHB2_receptor |
7.760e-08 |
0.03 |
EPHB |
Cell-Cell Contact |
PMID: 15114347 |
| Erythrocytes(Nos)_source |
JAM2_ligand |
Erythrocytes(Nos)_target |
JAM2_receptor |
1.182e-04 |
0.0 |
JAM |
Cell-Cell Contact |
KEGG: hsa04514 |
| Erythrocytes(Nos)_source |
NCAM1_ligand |
Erythrocytes(Nos)_target |
NCAM1_receptor |
1.256e-03 |
0.0 |
NCAM |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
NCAM1_ligand |
Erythrocytes(Nos)_target |
NCAM1_receptor |
5.628e-04 |
0.03 |
NCAM |
Cell-Cell Contact |
KEGG: hsa04514 |
| Erythrocytes(Nos)_source |
NCAM1_ligand |
HSC(Nos)_target |
NCAM1_receptor |
5.628e-04 |
0.03 |
NCAM |
Cell-Cell Contact |
KEGG: hsa04514 |
| Erythrocytes(Nos)_source |
DLK1_ligand |
Erythrocytes(Nos)_target |
NOTCH1_receptor |
9.411e-04 |
0.0 |
NOTCH |
Cell-Cell Contact |
PMID: 22353464 |
| Erythrocytes(Nos)_source |
DLK1_ligand |
HSC(Nos)_target |
NOTCH1_receptor |
1.039e-03 |
0.0 |
NOTCH |
Cell-Cell Contact |
PMID: 22353464 |
| HSC(Nos)_source |
DLK1_ligand |
HSC(Nos)_target |
NOTCH1_receptor |
1.028e-03 |
0.0 |
NOTCH |
Cell-Cell Contact |
PMID: 22353464 |
| Erythrocytes(Nos)_source |
DLK1_ligand |
Myocytes(Nos)_target |
NOTCH1_receptor |
2.928e-04 |
0.01 |
NOTCH |
Cell-Cell Contact |
PMID: 22353464 |
| Erythrocytes(Nos)_source |
SEMA6B_ligand |
Erythrocytes(Nos)_target |
PLXNA2_receptor |
2.215e-06 |
0.0 |
SEMA6 |
Cell-Cell Contact |
PMID: 27533782 |
| Erythrocytes(Nos)_source |
SEMA6B_ligand |
HSC(Nos)_target |
PLXNA2_receptor |
1.301e-06 |
0.04 |
SEMA6 |
Cell-Cell Contact |
PMID: 27533782 |