Sample overview
| Project Name |
TARGET-RT
|
| GSE ID |
GSE135564
|
| GSM ID |
GSM4017198
|
| Cell Line |
Rh41 cell line
|
| Tissue type |
None
|
| Disease Type |
human alveolar rhabdomyosarcoma
|
| PMID |
\
|
| Initial gene number |
33694
|
| Initial cell number |
7005
|
| Post-QC gene number |
8979
|
| Post-QC cell number |
3996
|
Bulk-to-ScRNA-seq Label Transfer
Bulk phenotype-associated subpopulations
Reference-Based Annotation
Differentially expressed genes
Overall Survival : Cluster
vs
There are no results of the analysis here
Overall Survival : Cluster
vs ( + )
There are no results of the analysis here
Clinical Stage : Cluster
vs
There
are no results of the analysis here
Tumor Size : Cluster
vs
There
are no results of the analysis here
Lymph Node Involvement : Cluster
vs
There
are no results of the analysis here
Distant Metastasis : Cluster
vs
There
are no results of the analysis here
Cell-Cell communications ( Survival-Associated Subpopulations Across Cell Types )
Cell Population Signaling and Communication
Ligand-Receptor-Mediated Cell-Cell Interactions
| Sending Cell Type |
Ligand |
Receiving Cell Type |
Receptor |
Score |
P-value |
Pathway Name |
Function |
Evidence |
| Erythrocytes(Nos)_source |
MSTN_ligand |
Erythrocytes(Nos)_target |
TGFBR1_ACVR2B_receptor |
2.381e-04 |
0.0 |
MSTN |
Secreted Signaling |
KEGG: hsa04060 |
| HSC(Nos)_source |
MSTN_ligand |
Erythrocytes(Nos)_target |
TGFBR1_ACVR2B_receptor |
1.480e-04 |
0.0 |
MSTN |
Secreted Signaling |
KEGG: hsa04060 |
| Erythrocytes(Nos)_source |
MSTN_ligand |
Erythrocytes(Nos)_target |
ACVR1B_ACVR2B_receptor |
8.330e-05 |
0.0 |
MSTN |
Secreted Signaling |
KEGG: hsa04060 |
| HSC(Nos)_source |
MSTN_ligand |
Erythrocytes(Nos)_target |
ACVR1B_ACVR2B_receptor |
5.176e-05 |
0.0 |
MSTN |
Secreted Signaling |
KEGG: hsa04060 |
| Erythrocytes(Nos)_source |
MSTN_ligand |
Erythrocytes(Nos)_target |
TGFBR1_ACVR2A_receptor |
1.112e-04 |
0.0 |
MSTN |
Secreted Signaling |
KEGG: hsa04060 |
| HSC(Nos)_source |
MSTN_ligand |
Erythrocytes(Nos)_target |
TGFBR1_ACVR2A_receptor |
6.911e-05 |
0.0 |
MSTN |
Secreted Signaling |
KEGG: hsa04060 |
| Erythrocytes(Nos)_source |
NRG1_ligand |
Erythrocytes(Nos)_target |
ERBB3_receptor |
3.839e-06 |
0.0 |
NRG |
Secreted Signaling |
KEGG: hsa04012 |
| Erythrocytes(Nos)_source |
FGF2_ligand |
Erythrocytes(Nos)_target |
FGFR1_receptor |
8.143e-04 |
0.0 |
FGF |
Secreted Signaling |
PMC: 4393358 |
| HSC(Nos)_source |
FGF2_ligand |
Erythrocytes(Nos)_target |
FGFR1_receptor |
4.196e-04 |
0.0 |
FGF |
Secreted Signaling |
PMC: 4393358 |
| Erythrocytes(Nos)_source |
FGF2_ligand |
Erythrocytes(Nos)_target |
FGFR2_receptor |
2.711e-04 |
0.0 |
FGF |
Secreted Signaling |
PMC: 4393358 |
| Erythrocytes(Nos)_source |
FGF2_ligand |
Erythrocytes(Nos)_target |
FGFR4_receptor |
2.484e-03 |
0.0 |
FGF |
Secreted Signaling |
PMC: 4393358 |
| Erythrocytes(Nos)_source |
FGF7_ligand |
Erythrocytes(Nos)_target |
FGFR1_receptor |
1.726e-03 |
0.0 |
FGF |
Secreted Signaling |
PMC: 4393358 |
| HSC(Nos)_source |
FGF7_ligand |
Erythrocytes(Nos)_target |
FGFR1_receptor |
1.122e-03 |
0.0 |
FGF |
Secreted Signaling |
PMC: 4393358 |
| HSC(Nos)_source |
FGF7_ligand |
Erythrocytes(Nos)_target |
FGFR2_receptor |
3.743e-04 |
0.0 |
FGF |
Secreted Signaling |
PMC: 4393358 |
| Erythrocytes(Nos)_source |
FGF8_ligand |
Erythrocytes(Nos)_target |
FGFR1_receptor |
2.234e-03 |
0.0 |
FGF |
Secreted Signaling |
PMC: 4393358 |
| HSC(Nos)_source |
FGF8_ligand |
Erythrocytes(Nos)_target |
FGFR1_receptor |
9.497e-04 |
0.0 |
FGF |
Secreted Signaling |
PMC: 4393358 |
| Erythrocytes(Nos)_source |
FGF8_ligand |
Erythrocytes(Nos)_target |
FGFR2_receptor |
7.453e-04 |
0.0 |
FGF |
Secreted Signaling |
PMC: 4393358 |
| Erythrocytes(Nos)_source |
FGF8_ligand |
HSC(Nos)_target |
FGFR2_receptor |
4.109e-04 |
0.0 |
FGF |
Secreted Signaling |
PMC: 4393358 |
| Erythrocytes(Nos)_source |
FGF8_ligand |
Erythrocytes(Nos)_target |
FGFR4_receptor |
6.765e-03 |
0.0 |
FGF |
Secreted Signaling |
PMC: 4393358 |
| HSC(Nos)_source |
IGF2_ligand |
Erythrocytes(Nos)_target |
IGF1R_receptor |
5.543e-05 |
0.0 |
IGF |
Secreted Signaling |
PMID: 14604834 |
| HSC(Nos)_source |
IGF2_ligand |
HSC(Nos)_target |
IGF1R_receptor |
3.227e-05 |
0.0 |
IGF |
Secreted Signaling |
PMID: 14604834 |
| Erythrocytes(Nos)_source |
IGF2_ligand |
Erythrocytes(Nos)_target |
IGF2R_receptor |
5.720e-03 |
0.02 |
IGF |
Secreted Signaling |
PMID: 14604834 |
| HSC(Nos)_source |
IGF2_ligand |
Erythrocytes(Nos)_target |
IGF2R_receptor |
3.454e-03 |
0.0 |
IGF |
Secreted Signaling |
PMID: 14604834 |
| HSC(Nos)_source |
IGF2_ligand |
HSC(Nos)_target |
IGF2R_receptor |
1.947e-03 |
0.02 |
IGF |
Secreted Signaling |
PMID: 14604834 |
| Erythrocytes(Nos)_source |
COL4A1_ligand |
Erythrocytes(Nos)_target |
SDC1_receptor |
2.988e-04 |
0.0 |
COLLAGEN |
ECM-Receptor |
KEGG: hsa04512 |
| Erythrocytes(Nos)_source |
COL4A2_ligand |
Erythrocytes(Nos)_target |
SDC1_receptor |
5.108e-04 |
0.0 |
COLLAGEN |
ECM-Receptor |
KEGG: hsa04512 |
| Erythrocytes(Nos)_source |
CD99_ligand |
Erythrocytes(Nos)_target |
CD99_receptor |
7.028e-03 |
0.01 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Erythrocytes(Nos)_source |
CDH4_ligand |
Erythrocytes(Nos)_target |
CDH4_receptor |
7.429e-04 |
0.0 |
CDH |
Cell-Cell Contact |
KEGG: hsa04514 |
| Erythrocytes(Nos)_source |
EFNA4_ligand |
Erythrocytes(Nos)_target |
EPHA4_receptor |
6.641e-05 |
0.02 |
EPHA |
Cell-Cell Contact |
PMID: 15114347 |
| Erythrocytes(Nos)_source |
EFNA4_ligand |
HSC(Nos)_target |
EPHA4_receptor |
4.545e-05 |
0.0 |
EPHA |
Cell-Cell Contact |
PMID: 15114347 |
| Erythrocytes(Nos)_source |
EFNA5_ligand |
HSC(Nos)_target |
EPHA4_receptor |
5.217e-05 |
0.0 |
EPHA |
Cell-Cell Contact |
PMID: 15114347 |
| HSC(Nos)_source |
EFNB2_ligand |
Erythrocytes(Nos)_target |
EPHA4_receptor |
6.916e-05 |
0.0 |
EPHB |
Cell-Cell Contact |
PMID: 15114347 |
| HSC(Nos)_source |
EFNB2_ligand |
HSC(Nos)_target |
EPHA4_receptor |
4.733e-05 |
0.0 |
EPHB |
Cell-Cell Contact |
PMID: 15114347 |
| Erythrocytes(Nos)_source |
EFNB3_ligand |
HSC(Nos)_target |
EPHA4_receptor |
1.611e-05 |
0.0 |
EPHB |
Cell-Cell Contact |
PMID: 15114347 |
| HSC(Nos)_source |
EFNB3_ligand |
HSC(Nos)_target |
EPHA4_receptor |
1.038e-05 |
0.0 |
EPHB |
Cell-Cell Contact |
PMID: 15114347 |
| Erythrocytes(Nos)_source |
DLL3_ligand |
Erythrocytes(Nos)_target |
NOTCH1_receptor |
5.547e-06 |
0.0 |
NOTCH |
Cell-Cell Contact |
PMID: 22353464 |
| Erythrocytes(Nos)_source |
DLL3_ligand |
Erythrocytes(Nos)_target |
NOTCH3_receptor |
2.035e-05 |
0.0 |
NOTCH |
Cell-Cell Contact |
PMID: 22353464 |
| Erythrocytes(Nos)_source |
SEMA6B_ligand |
Erythrocytes(Nos)_target |
PLXNA2_receptor |
2.278e-04 |
0.0 |
SEMA6 |
Cell-Cell Contact |
PMID: 27533782 |