Sample overview
| Project Name |
TARGET-ALL
|
| GSE ID |
GSE236136
|
| GSM ID |
GSM7518735
|
| Cell Line |
None
|
| Tissue type |
Bone Marrow;Peripheral Blood
|
| Disease Type |
B-cell acute lymphoblastic leukemia
|
| PMID |
37640845
|
| Initial gene number |
36601
|
| Initial cell number |
5553
|
| Post-QC gene number |
6174
|
| Post-QC cell number |
4097
|
Bulk-to-ScRNA-seq Label Transfer
Bulk phenotype-associated subpopulations
Reference-Based Annotation
Differentially expressed genes
Overall Survival : Cluster
vs
There are no results of the analysis here
Overall Survival : Cluster
vs ( + )
There are no results of the analysis here
Clinical Stage : Cluster
vs
There
are no results of the analysis here
Tumor Size : Cluster
vs
There
are no results of the analysis here
Lymph Node Involvement : Cluster
vs
There
are no results of the analysis here
Distant Metastasis : Cluster
vs
There
are no results of the analysis here
Cell-Cell communications ( Survival-Associated Subpopulations Across Cell Types )
Cell Population Signaling and Communication
Ligand-Receptor-Mediated Cell-Cell Interactions
| Sending Cell Type |
Ligand |
Receiving Cell Type |
Receptor |
Score |
P-value |
Pathway Name |
Function |
Evidence |
| HSC(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CXCR4_receptor |
4.142e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| HSC(Nos)_source |
MIF_ligand |
HSC(Nos)_target |
CD74_CXCR4_receptor |
2.822e-02 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| HSC(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CXCR4_receptor |
3.344e-02 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| HSC(Nos)_source |
MIF_ligand |
HSC(Nos)_target |
CD74_CD44_receptor |
1.780e-02 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| HSC(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
2.619e-02 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| HSC(Nos)_source |
LGALS9_ligand |
Monocytes(Nos)_target |
PTPRC_receptor |
1.080e-02 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| Monocytes(Nos)_source |
LGALS9_ligand |
Monocytes(Nos)_target |
PTPRC_receptor |
1.416e-02 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| HSC(Nos)_source |
LGALS9_ligand |
Monocytes(Nos)_target |
CD44_receptor |
8.438e-03 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| Monocytes(Nos)_source |
LGALS9_ligand |
Monocytes(Nos)_target |
CD44_receptor |
1.108e-02 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| HSC(Nos)_source |
ADGRE5_ligand |
Monocytes(Nos)_target |
CD55_receptor |
3.848e-03 |
0.0 |
ADGRE5 |
Cell-Cell Contact |
PMID: 11297558 |
| HSC(Nos)_source |
APP_ligand |
B-cells(Nos)_target |
CD74_receptor |
5.606e-05 |
0.0 |
APP |
Cell-Cell Contact |
PMID: 19849849 |
| HSC(Nos)_source |
APP_ligand |
Monocytes(Nos)_target |
CD74_receptor |
4.671e-03 |
0.0 |
APP |
Cell-Cell Contact |
PMID: 19849849 |
| HSC(Nos)_source |
CD22_ligand |
Monocytes(Nos)_target |
PTPRC_receptor |
4.718e-06 |
0.0 |
CD22 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
CD22_ligand |
Monocytes(Nos)_target |
PTPRC_receptor |
7.113e-06 |
0.0 |
CD22 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
PTPRC_ligand |
HSC(Nos)_target |
CD22_receptor |
4.718e-06 |
0.0 |
CD45 |
Cell-Cell Contact |
PMID: 12115612 |
| Monocytes(Nos)_source |
PTPRC_ligand |
Monocytes(Nos)_target |
CD22_receptor |
7.113e-06 |
0.0 |
CD45 |
Cell-Cell Contact |
PMID: 12115612 |
| HSC(Nos)_source |
CD99_ligand |
HSC(Nos)_target |
CD99_receptor |
7.690e-02 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
CD99_ligand |
HSC(Nos)_target |
CD99_receptor |
8.462e-02 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
CD99_ligand |
Monocytes(Nos)_target |
CD99_receptor |
8.462e-02 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
ICAM2_ligand |
Monocytes(Nos)_target |
ITGAL_ITGB2_receptor |
5.034e-04 |
0.0 |
ICAM |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
ICAM2_ligand |
Monocytes(Nos)_target |
ITGAL_ITGB2_receptor |
6.128e-04 |
0.0 |
ICAM |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
ITGB2_ligand |
HSC(Nos)_target |
ICAM2_receptor |
2.492e-03 |
0.0 |
ITGB2 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
ITGB2_ligand |
Monocytes(Nos)_target |
ICAM2_receptor |
3.033e-03 |
0.0 |
ITGB2 |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Nos)_source |
SELL_ligand |
HSC(Nos)_target |
CD34_receptor |
1.810e-05 |
0.0 |
SELL |
Cell-Cell Contact |
PMID: 7692600; PMID: 8977216 |
| HSC(Nos)_source |
SELL_ligand |
HSC(Nos)_target |
CD34_receptor |
5.315e-04 |
0.0 |
SELL |
Cell-Cell Contact |
PMID: 7692600; PMID: 8977216 |
| Monocytes(Nos)_source |
SELL_ligand |
HSC(Nos)_target |
CD34_receptor |
1.013e-03 |
0.0 |
SELL |
Cell-Cell Contact |
PMID: 7692600; PMID: 8977216 |