Sample overview
| Project Name |
TARGET-ALL
|
| GSE ID |
GSE227122
|
| GSM ID |
GSM7091998
|
| Cell Line |
None
|
| Tissue type |
Bone Marrow
|
| Disease Type |
T-cell acute lymphoblastic leukemia
|
| PMID |
\
|
| Initial gene number |
33538
|
| Initial cell number |
4034
|
| Post-QC gene number |
4918
|
| Post-QC cell number |
1314
|
Bulk-to-ScRNA-seq Label Transfer
Bulk phenotype-associated subpopulations
Reference-Based Annotation
Differentially expressed genes
Overall Survival : Cluster
vs
There are no results of the analysis here
Overall Survival : Cluster
vs ( + )
There are no results of the analysis here
Clinical Stage : Cluster
vs
There
are no results of the analysis here
Tumor Size : Cluster
vs
There
are no results of the analysis here
Lymph Node Involvement : Cluster
vs
There
are no results of the analysis here
Distant Metastasis : Cluster
vs
There
are no results of the analysis here
Cell-Cell communications ( Survival-Associated Subpopulations Across Cell Types )
Cell Population Signaling and Communication
Ligand-Receptor-Mediated Cell-Cell Interactions
| Sending Cell Type |
Ligand |
Receiving Cell Type |
Receptor |
Score |
P-value |
Pathway Name |
Function |
Evidence |
| CD8+,T-cells(Nos)_source |
IL4_ligand |
Erythrocytes(Nos)_target |
IL4R_IL2RG_receptor |
1.111e-04 |
0.01 |
IL2 |
Secreted Signaling |
KEGG: hsa04060 |
| Erythrocytes(Nos)_source |
IL4_ligand |
Erythrocytes(Nos)_target |
IL4R_IL2RG_receptor |
6.894e-05 |
0.01 |
IL2 |
Secreted Signaling |
KEGG: hsa04060 |
| HSC(Nos)_source |
IL4_ligand |
Erythrocytes(Nos)_target |
IL4R_IL2RG_receptor |
1.018e-04 |
0.0 |
IL2 |
Secreted Signaling |
KEGG: hsa04060 |
| Erythrocytes(Nos)_source |
IL4_ligand |
HSC(Nos)_target |
IL4R_IL2RG_receptor |
1.159e-04 |
0.0 |
IL2 |
Secreted Signaling |
KEGG: hsa04060 |
| CD8+,T-cells(Nos)_source |
IL4_ligand |
CD8+,T-cells(Nos)_target |
IL4R_receptor |
1.017e-04 |
0.04 |
IL4 |
Secreted Signaling |
KEGG: hsa04060 |
| Erythrocytes(Nos)_source |
IL4_ligand |
CD8+,T-cells(Nos)_target |
IL4R_receptor |
6.314e-05 |
0.0 |
IL4 |
Secreted Signaling |
KEGG: hsa04060 |
| HSC(Nos)_source |
IL4_ligand |
CD8+,T-cells(Nos)_target |
IL4R_receptor |
9.319e-05 |
0.0 |
IL4 |
Secreted Signaling |
KEGG: hsa04060 |
| CD8+,T-cells(Nos)_source |
IL4_ligand |
Erythrocytes(Nos)_target |
IL4R_receptor |
5.387e-05 |
0.0 |
IL4 |
Secreted Signaling |
KEGG: hsa04060 |
| Erythrocytes(Nos)_source |
IL4_ligand |
Erythrocytes(Nos)_target |
IL4R_receptor |
3.343e-05 |
0.01 |
IL4 |
Secreted Signaling |
KEGG: hsa04060 |
| HSC(Nos)_source |
IL4_ligand |
Erythrocytes(Nos)_target |
IL4R_receptor |
4.935e-05 |
0.0 |
IL4 |
Secreted Signaling |
KEGG: hsa04060 |
| Erythrocytes(Nos)_source |
IL4_ligand |
HSC(Nos)_target |
IL4R_receptor |
4.937e-05 |
0.01 |
IL4 |
Secreted Signaling |
KEGG: hsa04060 |
| Erythrocytes(Nos)_source |
IL16_ligand |
CD4+,T-cells(Nos)_target |
CD4_receptor |
1.717e-07 |
0.0 |
IL16 |
Secreted Signaling |
KEGG: hsa04060 |
| Erythrocytes(Nos)_source |
IL16_ligand |
CD8+,T-cells(Nos)_target |
CD4_receptor |
2.329e-06 |
0.0 |
IL16 |
Secreted Signaling |
KEGG: hsa04060 |
| Erythrocytes(Nos)_source |
IL16_ligand |
Erythrocytes(Nos)_target |
CD4_receptor |
1.475e-05 |
0.0 |
IL16 |
Secreted Signaling |
KEGG: hsa04060 |
| Erythrocytes(Nos)_source |
IL16_ligand |
HSC(Nos)_target |
CD4_receptor |
3.632e-05 |
0.0 |
IL16 |
Secreted Signaling |
KEGG: hsa04060 |
| CD8+,T-cells(Nos)_source |
CD99_ligand |
CD8+,T-cells(Nos)_target |
CD99_receptor |
6.787e-02 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
CD99_ligand |
CD8+,T-cells(Nos)_target |
CD99_receptor |
5.928e-02 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
CD99_ligand |
HSC(Nos)_target |
CD99_receptor |
5.928e-02 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Erythrocytes(Nos)_source |
MPZL1_ligand |
CD4+,T-cells(Nos)_target |
MPZL1_receptor |
5.664e-08 |
0.0 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| Erythrocytes(Nos)_source |
MPZL1_ligand |
CD8+,T-cells(Nos)_target |
MPZL1_receptor |
2.681e-07 |
0.0 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD4+,T-cells(Nos)_source |
MPZL1_ligand |
Erythrocytes(Nos)_target |
MPZL1_receptor |
5.664e-08 |
0.0 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
MPZL1_ligand |
Erythrocytes(Nos)_target |
MPZL1_receptor |
2.681e-07 |
0.0 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| Erythrocytes(Nos)_source |
MPZL1_ligand |
Erythrocytes(Nos)_target |
MPZL1_receptor |
6.650e-06 |
0.0 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
MPZL1_ligand |
Erythrocytes(Nos)_target |
MPZL1_receptor |
5.205e-07 |
0.0 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| Erythrocytes(Nos)_source |
MPZL1_ligand |
HSC(Nos)_target |
MPZL1_receptor |
5.205e-07 |
0.0 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |