Sample overview
| Project Name |
TARGET-ALL
|
| GSE ID |
GSE227122
|
| GSM ID |
GSM7091996
|
| Cell Line |
None
|
| Tissue type |
Bone Marrow
|
| Disease Type |
T-cell acute lymphoblastic leukemia
|
| PMID |
\
|
| Initial gene number |
33538
|
| Initial cell number |
3461
|
| Post-QC gene number |
3804
|
| Post-QC cell number |
1201
|
Bulk-to-ScRNA-seq Label Transfer
Bulk phenotype-associated subpopulations
Reference-Based Annotation
Differentially expressed genes
Overall Survival : Cluster
vs
There are no results of the analysis here
Overall Survival : Cluster
vs ( + )
There are no results of the analysis here
Clinical Stage : Cluster
vs
There
are no results of the analysis here
Tumor Size : Cluster
vs
There
are no results of the analysis here
Lymph Node Involvement : Cluster
vs
There
are no results of the analysis here
Distant Metastasis : Cluster
vs
There
are no results of the analysis here
Cell-Cell communications ( Survival-Associated Subpopulations Across Cell Types )
Cell Population Signaling and Communication
Ligand-Receptor-Mediated Cell-Cell Interactions
| Sending Cell Type |
Ligand |
Receiving Cell Type |
Receptor |
Score |
P-value |
Pathway Name |
Function |
Evidence |
| HSC(Nos)_source |
MIF_ligand |
CD8+,T-cells(Nos)_target |
CD74_CXCR4_receptor |
5.453e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| CD8+,T-cells(Nos)_source |
MIF_ligand |
HSC(Nos)_target |
CD74_CXCR4_receptor |
4.885e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| HSC(Nos)_source |
MIF_ligand |
HSC(Nos)_target |
CD74_CXCR4_receptor |
1.538e-02 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| HSC(Nos)_source |
MDK_ligand |
CD8+,T-cells(Nos)_target |
ITGA4_ITGB1_receptor |
3.972e-04 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| HSC(Nos)_source |
MDK_ligand |
HSC(Nos)_target |
ITGA4_ITGB1_receptor |
2.135e-03 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| HSC(Nos)_source |
MDK_ligand |
CD8+,T-cells(Nos)_target |
NCL_receptor |
1.825e-03 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| HSC(Nos)_source |
MDK_ligand |
HSC(Nos)_target |
NCL_receptor |
6.626e-03 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| HSC(Nos)_source |
LGALS9_ligand |
CD8+,T-cells(Nos)_target |
PTPRC_receptor |
2.739e-03 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| HSC(Nos)_source |
LGALS9_ligand |
HSC(Nos)_target |
PTPRC_receptor |
4.300e-03 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| HSC(Nos)_source |
APP_ligand |
HSC(Nos)_target |
CD74_receptor |
3.664e-03 |
0.0 |
APP |
Cell-Cell Contact |
PMID: 19849849 |
| HSC(Nos)_source |
CD99_ligand |
CD8+,T-cells(Nos)_target |
CD99_receptor |
5.769e-02 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
CD99_ligand |
HSC(Nos)_target |
CD99_receptor |
5.769e-02 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
CD99_ligand |
HSC(Nos)_target |
CD99_receptor |
1.632e-01 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
ITGB2_ligand |
HSC(Nos)_target |
ICAM2_receptor |
3.588e-04 |
0.0 |
ITGB2 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
ITGB2_ligand |
HSC(Nos)_target |
ICAM2_receptor |
8.844e-04 |
0.0 |
ITGB2 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
PECAM1_ligand |
HSC(Nos)_target |
PECAM1_receptor |
6.584e-04 |
0.0 |
PECAM1 |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
SELL_ligand |
HSC(Nos)_target |
CD34_receptor |
5.880e-04 |
0.0 |
SELL |
Cell-Cell Contact |
PMID: 7692600; PMID: 8977216 |
| HSC(Nos)_source |
SELL_ligand |
HSC(Nos)_target |
CD34_receptor |
7.633e-03 |
0.0 |
SELL |
Cell-Cell Contact |
PMID: 7692600; PMID: 8977216 |