Sample overview
| Project Name |
TARGET-ALL
|
| GSE ID |
GSE220476
|
| GSM ID |
GSM6805348
|
| Cell Line |
None
|
| Tissue type |
Bone Marrow
|
| Disease Type |
KMT2A-r acute lymphoblastic leukemia
|
| PMID |
38822412
|
| Initial gene number |
36601
|
| Initial cell number |
6062
|
| Post-QC gene number |
8421
|
| Post-QC cell number |
4929
|
Bulk-to-ScRNA-seq Label Transfer
Bulk phenotype-associated subpopulations
Reference-Based Annotation
Differentially expressed genes
Overall Survival : Cluster
vs
There are no results of the analysis here
Overall Survival : Cluster
vs ( + )
There are no results of the analysis here
Clinical Stage : Cluster
vs
There
are no results of the analysis here
Tumor Size : Cluster
vs
There
are no results of the analysis here
Lymph Node Involvement : Cluster
vs
There
are no results of the analysis here
Distant Metastasis : Cluster
vs
There
are no results of the analysis here
Cell-Cell communications ( Survival-Associated Subpopulations Across Cell Types )
Cell Population Signaling and Communication
Ligand-Receptor-Mediated Cell-Cell Interactions
| Sending Cell Type |
Ligand |
Receiving Cell Type |
Receptor |
Score |
P-value |
Pathway Name |
Function |
Evidence |
| Erythrocytes(Nos)_source |
PDGFA_ligand |
HSC(Nos)_target |
PDGFRB_receptor |
4.848e-06 |
0.0 |
PDGF |
Secreted Signaling |
PMID: 15207812 |
| HSC(Nos)_source |
PDGFA_ligand |
HSC(Nos)_target |
PDGFRB_receptor |
1.508e-05 |
0.0 |
PDGF |
Secreted Signaling |
PMID: 15207812 |
| Erythrocytes(Nos)_source |
MIF_ligand |
HSC(Nos)_target |
CD74_CXCR4_receptor |
1.513e-02 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| Erythrocytes(Nos)_source |
MIF_ligand |
Erythrocytes(Nos)_target |
CD74_CD44_receptor |
3.176e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| HSC(Nos)_source |
MIF_ligand |
Erythrocytes(Nos)_target |
CD74_CD44_receptor |
1.075e-02 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Erythrocytes(Nos)_source |
MIF_ligand |
HSC(Nos)_target |
CD74_CD44_receptor |
9.285e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| HSC(Nos)_source |
MIF_ligand |
HSC(Nos)_target |
CD74_CD44_receptor |
3.139e-02 |
0.01 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Erythrocytes(Nos)_source |
RETN_ligand |
Erythrocytes(Nos)_target |
CAP1_receptor |
4.981e-04 |
0.0 |
RESISTIN |
Secreted Signaling |
PMID: 30809105 |
| Erythrocytes(Nos)_source |
RETN_ligand |
HSC(Nos)_target |
CAP1_receptor |
1.621e-03 |
0.01 |
RESISTIN |
Secreted Signaling |
PMID: 30809105 |
| Erythrocytes(Nos)_source |
MDK_ligand |
Erythrocytes(Nos)_target |
ITGA4_ITGB1_receptor |
9.098e-04 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| Erythrocytes(Nos)_source |
MDK_ligand |
HSC(Nos)_target |
ITGA4_ITGB1_receptor |
3.352e-03 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| Erythrocytes(Nos)_source |
MDK_ligand |
Erythrocytes(Nos)_target |
ITGA6_ITGB1_receptor |
4.727e-04 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| Erythrocytes(Nos)_source |
MDK_ligand |
HSC(Nos)_target |
ITGA6_ITGB1_receptor |
1.729e-03 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| Erythrocytes(Nos)_source |
MDK_ligand |
Erythrocytes(Nos)_target |
NCL_receptor |
2.506e-03 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| Erythrocytes(Nos)_source |
MDK_ligand |
HSC(Nos)_target |
NCL_receptor |
8.890e-03 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| Erythrocytes(Nos)_source |
APP_ligand |
HSC(Nos)_target |
CD74_receptor |
2.794e-04 |
0.0 |
APP |
Cell-Cell Contact |
PMID: 19849849 |
| HSC(Nos)_source |
CD22_ligand |
Erythrocytes(Nos)_target |
PTPRC_receptor |
1.694e-03 |
0.0 |
CD22 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
CD22_ligand |
HSC(Nos)_target |
PTPRC_receptor |
6.278e-03 |
0.0 |
CD22 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Erythrocytes(Nos)_source |
PTPRC_ligand |
HSC(Nos)_target |
CD22_receptor |
1.694e-03 |
0.0 |
CD45 |
Cell-Cell Contact |
PMID: 12115612 |
| HSC(Nos)_source |
PTPRC_ligand |
HSC(Nos)_target |
CD22_receptor |
6.278e-03 |
0.0 |
CD45 |
Cell-Cell Contact |
PMID: 12115612 |
| HSC(Nos)_source |
CD99_ligand |
HSC(Nos)_target |
CD99_receptor |
1.571e-01 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
MPZL1_ligand |
HSC(Nos)_target |
MPZL1_receptor |
3.246e-06 |
0.01 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
NEGR1_ligand |
HSC(Nos)_target |
NEGR1_receptor |
1.940e-02 |
0.0 |
NEGR |
Cell-Cell Contact |
KEGG: hsa04514 |