Sample overview
| Project Name |
TARGET-ALL
|
| GSE ID |
GSE220476
|
| GSM ID |
GSM6805347
|
| Cell Line |
None
|
| Tissue type |
Bone Marrow
|
| Disease Type |
KMT2A-r acute lymphoblastic leukemia
|
| PMID |
38822412
|
| Initial gene number |
36601
|
| Initial cell number |
5952
|
| Post-QC gene number |
8528
|
| Post-QC cell number |
4741
|
Bulk-to-ScRNA-seq Label Transfer
Bulk phenotype-associated subpopulations
Reference-Based Annotation
Differentially expressed genes
Overall Survival : Cluster
vs
There are no results of the analysis here
Overall Survival : Cluster
vs ( + )
There are no results of the analysis here
Clinical Stage : Cluster
vs
There
are no results of the analysis here
Tumor Size : Cluster
vs
There
are no results of the analysis here
Lymph Node Involvement : Cluster
vs
There
are no results of the analysis here
Distant Metastasis : Cluster
vs
There
are no results of the analysis here
Cell-Cell communications ( Survival-Associated Subpopulations Across Cell Types )
Cell Population Signaling and Communication
Ligand-Receptor-Mediated Cell-Cell Interactions
| Sending Cell Type |
Ligand |
Receiving Cell Type |
Receptor |
Score |
P-value |
Pathway Name |
Function |
Evidence |
| HSC(Nos)_source |
MIF_ligand |
Erythrocytes(Nos)_target |
CD74_CXCR4_receptor |
1.297e-02 |
0.02 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| HSC(Nos)_source |
MIF_ligand |
Erythrocytes(Nos)_target |
CD74_CD44_receptor |
1.187e-02 |
0.03 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| HSC(Nos)_source |
MDK_ligand |
Erythrocytes(Nos)_target |
ITGA6_ITGB1_receptor |
1.091e-03 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| HSC(Nos)_source |
MDK_ligand |
HSC(Nos)_target |
NCL_receptor |
2.152e-02 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| Erythrocytes(Nos)_source |
HLA-E_ligand |
Erythrocytes(Nos)_target |
KLRK1_receptor |
1.655e-03 |
0.0 |
MHC-I |
Cell-Cell Contact |
PMID: 28484462 |
| HSC(Nos)_source |
HLA-E_ligand |
Erythrocytes(Nos)_target |
KLRK1_receptor |
5.605e-03 |
0.0 |
MHC-I |
Cell-Cell Contact |
PMID: 28484462 |
| Erythrocytes(Nos)_source |
HLA-E_ligand |
HSC(Nos)_target |
KLRK1_receptor |
5.918e-03 |
0.0 |
MHC-I |
Cell-Cell Contact |
PMID: 28484462 |
| Erythrocytes(Nos)_source |
MPZL1_ligand |
Erythrocytes(Nos)_target |
MPZL1_receptor |
1.141e-05 |
0.0 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
MPZL1_ligand |
Erythrocytes(Nos)_target |
MPZL1_receptor |
6.134e-06 |
0.0 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| Erythrocytes(Nos)_source |
MPZL1_ligand |
HSC(Nos)_target |
MPZL1_receptor |
6.134e-06 |
0.0 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| Erythrocytes(Nos)_source |
SEMA4D_ligand |
Erythrocytes(Nos)_target |
PLXNB2_receptor |
8.801e-06 |
0.0 |
SEMA4 |
Cell-Cell Contact |
PMID: 27533782 |
| HSC(Nos)_source |
SEMA4D_ligand |
Erythrocytes(Nos)_target |
PLXNB2_receptor |
1.412e-07 |
0.01 |
SEMA4 |
Cell-Cell Contact |
PMID: 27533782 |