Sample overview
| Project Name |
TARGET-ALL
|
| GSE ID |
GSE196214
|
| GSM ID |
GSM5862877
|
| Cell Line |
None
|
| Tissue type |
Bone Marrow
|
| Disease Type |
Diagnosis
|
| PMID |
\
|
| Initial gene number |
33538
|
| Initial cell number |
1216
|
| Post-QC gene number |
2033
|
| Post-QC cell number |
1029
|
Bulk-to-ScRNA-seq Label Transfer
Bulk phenotype-associated subpopulations
Reference-Based Annotation
Differentially expressed genes
Overall Survival : Cluster
vs
There are no results of the analysis here
Overall Survival : Cluster
vs ( + )
There are no results of the analysis here
Clinical Stage : Cluster
vs
There
are no results of the analysis here
Tumor Size : Cluster
vs
There
are no results of the analysis here
Lymph Node Involvement : Cluster
vs
There
are no results of the analysis here
Distant Metastasis : Cluster
vs
There
are no results of the analysis here
Cell-Cell communications ( Survival-Associated Subpopulations Across Cell Types )
Cell Population Signaling and Communication
Ligand-Receptor-Mediated Cell-Cell Interactions
| Sending Cell Type |
Ligand |
Receiving Cell Type |
Receptor |
Score |
P-value |
Pathway Name |
Function |
Evidence |
| B-cells(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CXCR4_receptor |
9.589e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| HSC(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CXCR4_receptor |
1.739e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| B-cells(Nos)_source |
MIF_ligand |
HSC(Nos)_target |
CD74_CXCR4_receptor |
1.267e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| HSC(Nos)_source |
MIF_ligand |
HSC(Nos)_target |
CD74_CXCR4_receptor |
2.301e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| B-cells(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CXCR4_receptor |
4.194e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| HSC(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CXCR4_receptor |
7.621e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| B-cells(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CD44_receptor |
7.375e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| HSC(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CD44_receptor |
1.342e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| B-cells(Nos)_source |
MIF_ligand |
HSC(Nos)_target |
CD74_CD44_receptor |
9.407e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| HSC(Nos)_source |
MIF_ligand |
HSC(Nos)_target |
CD74_CD44_receptor |
1.714e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| B-cells(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
3.402e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| HSC(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
6.197e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| HSC(Nos)_source |
MDK_ligand |
B-cells(Nos)_target |
SDC2_receptor |
4.283e-04 |
0.01 |
MK |
Secreted Signaling |
PMID: 28356350 |
| B-cells(Nos)_source |
MDK_ligand |
HSC(Nos)_target |
SDC2_receptor |
4.432e-04 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| HSC(Nos)_source |
MDK_ligand |
HSC(Nos)_target |
SDC2_receptor |
1.027e-03 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| B-cells(Nos)_source |
MDK_ligand |
Monocytes(Nos)_target |
SDC2_receptor |
8.833e-04 |
0.03 |
MK |
Secreted Signaling |
PMID: 28356350 |
| HSC(Nos)_source |
MDK_ligand |
Monocytes(Nos)_target |
SDC2_receptor |
2.056e-03 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| HSC(Nos)_source |
MDK_ligand |
B-cells(Nos)_target |
ITGA4_ITGB1_receptor |
5.438e-04 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| B-cells(Nos)_source |
MDK_ligand |
HSC(Nos)_target |
ITGA4_ITGB1_receptor |
4.761e-04 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| HSC(Nos)_source |
MDK_ligand |
HSC(Nos)_target |
ITGA4_ITGB1_receptor |
1.102e-03 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| HSC(Nos)_source |
MDK_ligand |
Monocytes(Nos)_target |
ITGA4_ITGB1_receptor |
2.369e-03 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| HSC(Nos)_source |
MDK_ligand |
B-cells(Nos)_target |
ITGA6_ITGB1_receptor |
7.887e-04 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| B-cells(Nos)_source |
MDK_ligand |
HSC(Nos)_target |
ITGA6_ITGB1_receptor |
6.715e-04 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| HSC(Nos)_source |
MDK_ligand |
HSC(Nos)_target |
ITGA6_ITGB1_receptor |
1.547e-03 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| HSC(Nos)_source |
MDK_ligand |
Monocytes(Nos)_target |
ITGA6_ITGB1_receptor |
4.018e-03 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| HSC(Nos)_source |
MDK_ligand |
B-cells(Nos)_target |
NCL_receptor |
1.670e-03 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| B-cells(Nos)_source |
MDK_ligand |
HSC(Nos)_target |
NCL_receptor |
1.236e-03 |
0.01 |
MK |
Secreted Signaling |
PMID: 28356350 |
| HSC(Nos)_source |
MDK_ligand |
HSC(Nos)_target |
NCL_receptor |
2.812e-03 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| HSC(Nos)_source |
MDK_ligand |
Monocytes(Nos)_target |
NCL_receptor |
8.178e-03 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| B-cells(Nos)_source |
LGALS9_ligand |
B-cells(Nos)_target |
PTPRC_receptor |
7.719e-04 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| HSC(Nos)_source |
LGALS9_ligand |
B-cells(Nos)_target |
PTPRC_receptor |
8.499e-04 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| B-cells(Nos)_source |
LGALS9_ligand |
HSC(Nos)_target |
PTPRC_receptor |
1.013e-03 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| HSC(Nos)_source |
LGALS9_ligand |
HSC(Nos)_target |
PTPRC_receptor |
1.114e-03 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| B-cells(Nos)_source |
LGALS9_ligand |
Monocytes(Nos)_target |
PTPRC_receptor |
3.150e-03 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| HSC(Nos)_source |
LGALS9_ligand |
Monocytes(Nos)_target |
PTPRC_receptor |
3.461e-03 |
0.02 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| B-cells(Nos)_source |
LGALS9_ligand |
B-cells(Nos)_target |
CD44_receptor |
9.018e-04 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| HSC(Nos)_source |
LGALS9_ligand |
B-cells(Nos)_target |
CD44_receptor |
9.948e-04 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| B-cells(Nos)_source |
LGALS9_ligand |
HSC(Nos)_target |
CD44_receptor |
1.092e-03 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| B-cells(Nos)_source |
LGALS9_ligand |
Monocytes(Nos)_target |
CD44_receptor |
4.131e-03 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| HSC(Nos)_source |
LGALS9_ligand |
Monocytes(Nos)_target |
CD44_receptor |
4.551e-03 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| B-cells(Nos)_source |
CD22_ligand |
B-cells(Nos)_target |
PTPRC_receptor |
4.435e-04 |
0.0 |
CD22 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
CD22_ligand |
B-cells(Nos)_target |
PTPRC_receptor |
4.849e-04 |
0.01 |
CD22 |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Nos)_source |
CD22_ligand |
HSC(Nos)_target |
PTPRC_receptor |
5.808e-04 |
0.0 |
CD22 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
CD22_ligand |
HSC(Nos)_target |
PTPRC_receptor |
6.346e-04 |
0.01 |
CD22 |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Nos)_source |
CD22_ligand |
Monocytes(Nos)_target |
PTPRC_receptor |
1.803e-03 |
0.0 |
CD22 |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Nos)_source |
PTPRC_ligand |
B-cells(Nos)_target |
CD22_receptor |
4.435e-04 |
0.0 |
CD45 |
Cell-Cell Contact |
PMID: 12115612 |
| HSC(Nos)_source |
PTPRC_ligand |
B-cells(Nos)_target |
CD22_receptor |
5.808e-04 |
0.0 |
CD45 |
Cell-Cell Contact |
PMID: 12115612 |
| Monocytes(Nos)_source |
PTPRC_ligand |
B-cells(Nos)_target |
CD22_receptor |
1.803e-03 |
0.0 |
CD45 |
Cell-Cell Contact |
PMID: 12115612 |
| B-cells(Nos)_source |
PTPRC_ligand |
HSC(Nos)_target |
CD22_receptor |
4.849e-04 |
0.01 |
CD45 |
Cell-Cell Contact |
PMID: 12115612 |
| HSC(Nos)_source |
PTPRC_ligand |
HSC(Nos)_target |
CD22_receptor |
6.346e-04 |
0.01 |
CD45 |
Cell-Cell Contact |
PMID: 12115612 |
| B-cells(Nos)_source |
PTPRM_ligand |
B-cells(Nos)_target |
PTPRM_receptor |
3.738e-04 |
0.0 |
PTPRM |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
PTPRM_ligand |
B-cells(Nos)_target |
PTPRM_receptor |
3.498e-04 |
0.0 |
PTPRM |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
PTPRM_ligand |
B-cells(Nos)_target |
PTPRM_receptor |
8.552e-04 |
0.0 |
PTPRM |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Nos)_source |
PTPRM_ligand |
HSC(Nos)_target |
PTPRM_receptor |
3.498e-04 |
0.0 |
PTPRM |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Nos)_source |
PTPRM_ligand |
Monocytes(Nos)_target |
PTPRM_receptor |
8.552e-04 |
0.0 |
PTPRM |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
PTPRM_ligand |
Monocytes(Nos)_target |
PTPRM_receptor |
1.944e-03 |
0.0 |
PTPRM |
Cell-Cell Contact |
KEGG: hsa04514 |