Sample overview
| Project Name |
TARGET-ALL
|
| GSE ID |
GSE196214
|
| GSM ID |
GSM5862873
|
| Cell Line |
None
|
| Tissue type |
Bone Marrow
|
| Disease Type |
Diagnosis
|
| PMID |
\
|
| Initial gene number |
33538
|
| Initial cell number |
2829
|
| Post-QC gene number |
4776
|
| Post-QC cell number |
2631
|
Bulk-to-ScRNA-seq Label Transfer
Bulk phenotype-associated subpopulations
Reference-Based Annotation
Differentially expressed genes
Overall Survival : Cluster
vs
There are no results of the analysis here
Overall Survival : Cluster
vs ( + )
There are no results of the analysis here
Clinical Stage : Cluster
vs
There
are no results of the analysis here
Tumor Size : Cluster
vs
There
are no results of the analysis here
Lymph Node Involvement : Cluster
vs
There
are no results of the analysis here
Distant Metastasis : Cluster
vs
There
are no results of the analysis here
Cell-Cell communications ( Survival-Associated Subpopulations Across Cell Types )
Cell Population Signaling and Communication
Ligand-Receptor-Mediated Cell-Cell Interactions
| Sending Cell Type |
Ligand |
Receiving Cell Type |
Receptor |
Score |
P-value |
Pathway Name |
Function |
Evidence |
| HSC(Nos)_source |
MIF_ligand |
HSC(Nos)_target |
CD74_CXCR4_receptor |
5.305e-02 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| HSC(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CXCR4_receptor |
2.065e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| HSC(Nos)_source |
MIF_ligand |
HSC(Nos)_target |
CD74_CD44_receptor |
3.422e-02 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| HSC(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
1.599e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| HSC(Nos)_source |
TNF_ligand |
CD8+,T-cells(Nos)_target |
TNFRSF1A_receptor |
4.719e-06 |
0.04 |
TNF |
Secreted Signaling |
KEGG: hsa04060 |
| HSC(Nos)_source |
MDK_ligand |
HSC(Nos)_target |
SDC2_receptor |
7.112e-03 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| HSC(Nos)_source |
MDK_ligand |
Monocytes(Nos)_target |
SDC2_receptor |
1.014e-03 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| HSC(Nos)_source |
MDK_ligand |
HSC(Nos)_target |
NCL_receptor |
3.183e-02 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| B-cells(Nos)_source |
LGALS9_ligand |
CD8+,T-cells(Nos)_target |
PTPRC_receptor |
8.657e-05 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| HSC(Nos)_source |
LGALS9_ligand |
CD8+,T-cells(Nos)_target |
PTPRC_receptor |
4.389e-04 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| Monocytes(Nos)_source |
LGALS9_ligand |
CD8+,T-cells(Nos)_target |
PTPRC_receptor |
2.138e-05 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| HSC(Nos)_source |
LGALS9_ligand |
HSC(Nos)_target |
PTPRC_receptor |
2.653e-03 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| Monocytes(Nos)_source |
LGALS9_ligand |
HSC(Nos)_target |
PTPRC_receptor |
1.296e-04 |
0.04 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| HSC(Nos)_source |
LGALS9_ligand |
Monocytes(Nos)_target |
PTPRC_receptor |
1.064e-04 |
0.02 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| Monocytes(Nos)_source |
LGALS9_ligand |
Monocytes(Nos)_target |
PTPRC_receptor |
5.198e-06 |
0.04 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| HSC(Nos)_source |
LGALS9_ligand |
B-cells(Nos)_target |
CD44_receptor |
1.042e-03 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| B-cells(Nos)_source |
LGALS9_ligand |
CD8+,T-cells(Nos)_target |
CD44_receptor |
1.068e-04 |
0.04 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| HSC(Nos)_source |
LGALS9_ligand |
CD8+,T-cells(Nos)_target |
CD44_receptor |
5.411e-04 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| Monocytes(Nos)_source |
LGALS9_ligand |
CD8+,T-cells(Nos)_target |
CD44_receptor |
2.633e-05 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| HSC(Nos)_source |
LGALS9_ligand |
HSC(Nos)_target |
CD44_receptor |
6.140e-03 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| Monocytes(Nos)_source |
LGALS9_ligand |
HSC(Nos)_target |
CD44_receptor |
2.993e-04 |
0.03 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| B-cells(Nos)_source |
LGALS9_ligand |
Monocytes(Nos)_target |
CD44_receptor |
6.195e-05 |
0.04 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| HSC(Nos)_source |
LGALS9_ligand |
Monocytes(Nos)_target |
CD44_receptor |
3.138e-04 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| Monocytes(Nos)_source |
LGALS9_ligand |
Monocytes(Nos)_target |
CD44_receptor |
1.527e-05 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| HSC(Nos)_source |
APP_ligand |
B-cells(Nos)_target |
CD74_receptor |
1.909e-03 |
0.0 |
APP |
Cell-Cell Contact |
PMID: 19849849 |
| HSC(Nos)_source |
APP_ligand |
CD8+,T-cells(Nos)_target |
CD74_receptor |
2.175e-04 |
0.0 |
APP |
Cell-Cell Contact |
PMID: 19849849 |
| HSC(Nos)_source |
APP_ligand |
HSC(Nos)_target |
CD74_receptor |
6.266e-03 |
0.0 |
APP |
Cell-Cell Contact |
PMID: 19849849 |
| HSC(Nos)_source |
APP_ligand |
Monocytes(Nos)_target |
CD74_receptor |
2.760e-04 |
0.0 |
APP |
Cell-Cell Contact |
PMID: 19849849 |
| B-cells(Nos)_source |
CD22_ligand |
CD8+,T-cells(Nos)_target |
PTPRC_receptor |
4.849e-05 |
0.01 |
CD22 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
CD22_ligand |
CD8+,T-cells(Nos)_target |
PTPRC_receptor |
2.642e-04 |
0.0 |
CD22 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
CD22_ligand |
HSC(Nos)_target |
PTPRC_receptor |
1.591e-03 |
0.0 |
CD22 |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
PTPRC_ligand |
B-cells(Nos)_target |
CD22_receptor |
4.849e-05 |
0.01 |
CD45 |
Cell-Cell Contact |
PMID: 12115612 |
| CD8+,T-cells(Nos)_source |
PTPRC_ligand |
HSC(Nos)_target |
CD22_receptor |
2.642e-04 |
0.0 |
CD45 |
Cell-Cell Contact |
PMID: 12115612 |
| HSC(Nos)_source |
PTPRC_ligand |
HSC(Nos)_target |
CD22_receptor |
1.591e-03 |
0.0 |
CD45 |
Cell-Cell Contact |
PMID: 12115612 |
| B-cells(Nos)_source |
CD99_ligand |
B-cells(Nos)_target |
CD99_receptor |
1.793e-02 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
CD99_ligand |
B-cells(Nos)_target |
CD99_receptor |
5.527e-02 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Nos)_source |
CD99_ligand |
HSC(Nos)_target |
CD99_receptor |
5.527e-02 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
ITGB2_ligand |
HSC(Nos)_target |
ICAM2_receptor |
2.230e-04 |
0.0 |
ITGB2 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
ITGB2_ligand |
HSC(Nos)_target |
ICAM2_receptor |
5.973e-03 |
0.0 |
ITGB2 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
ITGB2_ligand |
HSC(Nos)_target |
ICAM2_receptor |
4.242e-04 |
0.0 |
ITGB2 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
MPZL1_ligand |
HSC(Nos)_target |
MPZL1_receptor |
3.512e-07 |
0.0 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
PECAM1_ligand |
HSC(Nos)_target |
PECAM1_receptor |
2.788e-04 |
0.0 |
PECAM1 |
Cell-Cell Contact |
KEGG: hsa04514 |