Sample overview
| Project Name |
TARGET-ALL
|
| GSE ID |
GSE196214
|
| GSM ID |
GSM5862870
|
| Cell Line |
None
|
| Tissue type |
Bone Marrow
|
| Disease Type |
Relapse
|
| PMID |
\
|
| Initial gene number |
33538
|
| Initial cell number |
4854
|
| Post-QC gene number |
7136
|
| Post-QC cell number |
4669
|
Bulk-to-ScRNA-seq Label Transfer
Bulk phenotype-associated subpopulations
Reference-Based Annotation
Differentially expressed genes
Overall Survival : Cluster
vs
There are no results of the analysis here
Overall Survival : Cluster
vs ( + )
There are no results of the analysis here
Clinical Stage : Cluster
vs
There
are no results of the analysis here
Tumor Size : Cluster
vs
There
are no results of the analysis here
Lymph Node Involvement : Cluster
vs
There
are no results of the analysis here
Distant Metastasis : Cluster
vs
There
are no results of the analysis here
Cell-Cell communications ( Survival-Associated Subpopulations Across Cell Types )
Cell Population Signaling and Communication
Ligand-Receptor-Mediated Cell-Cell Interactions
| Sending Cell Type |
Ligand |
Receiving Cell Type |
Receptor |
Score |
P-value |
Pathway Name |
Function |
Evidence |
| CD8+,T-cells(Nos)_source |
TGFB1_ligand |
HSC(Nos)_target |
TGFbR1_R2_receptor |
8.702e-05 |
0.0 |
TGFb |
Secreted Signaling |
KEGG: hsa04350 |
| HSC(Nos)_source |
TGFB1_ligand |
HSC(Nos)_target |
TGFbR1_R2_receptor |
4.020e-04 |
0.0 |
TGFb |
Secreted Signaling |
KEGG: hsa04350 |
| Monocytes(Nos)_source |
TGFB1_ligand |
HSC(Nos)_target |
TGFbR1_R2_receptor |
1.141e-03 |
0.0 |
TGFb |
Secreted Signaling |
KEGG: hsa04350 |
| CD8+,T-cells(Nos)_source |
TGFB1_ligand |
Monocytes(Nos)_target |
TGFbR1_R2_receptor |
1.459e-04 |
0.0 |
TGFb |
Secreted Signaling |
KEGG: hsa04350 |
| CD8+,T-cells(Nos)_source |
TGFB1_ligand |
HSC(Nos)_target |
ACVR1B_TGFbR2_receptor |
2.040e-05 |
0.0 |
TGFb |
Secreted Signaling |
PMID: 27449815 |
| Monocytes(Nos)_source |
TGFB1_ligand |
HSC(Nos)_target |
ACVR1B_TGFbR2_receptor |
2.674e-04 |
0.0 |
TGFb |
Secreted Signaling |
PMID: 27449815 |
| CD8+,T-cells(Nos)_source |
TGFB1_ligand |
Monocytes(Nos)_target |
ACVR1B_TGFbR2_receptor |
4.571e-05 |
0.0 |
TGFb |
Secreted Signaling |
PMID: 27449815 |
| Monocytes(Nos)_source |
TGFB1_ligand |
Monocytes(Nos)_target |
ACVR1B_TGFbR2_receptor |
5.991e-04 |
0.0 |
TGFb |
Secreted Signaling |
PMID: 27449815 |
| HSC(Nos)_source |
MIF_ligand |
CD8+,T-cells(Nos)_target |
CD74_CXCR4_receptor |
3.474e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| HSC(Nos)_source |
MIF_ligand |
HSC(Nos)_target |
CD74_CXCR4_receptor |
2.763e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| HSC(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CXCR4_receptor |
6.489e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| HSC(Nos)_source |
MIF_ligand |
HSC(Nos)_target |
CD74_CD44_receptor |
2.991e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| HSC(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
7.906e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Monocytes(Nos)_source |
NAMPT_ligand |
HSC(Nos)_target |
INSR_receptor |
8.415e-04 |
0.0 |
VISFATIN |
Secreted Signaling |
PMID: 28490838 |
| Monocytes(Nos)_source |
NAMPT_ligand |
Monocytes(Nos)_target |
INSR_receptor |
1.943e-03 |
0.0 |
VISFATIN |
Secreted Signaling |
PMID: 28490838 |
| Monocytes(Nos)_source |
NAMPT_ligand |
Monocytes(Nos)_target |
ITGA5_ITGB1_receptor |
5.443e-04 |
0.0 |
VISFATIN |
Secreted Signaling |
PMID: 28490838 |
| Monocytes(Nos)_source |
COL6A1_ligand |
HSC(Nos)_target |
CD44_receptor |
3.302e-03 |
0.0 |
COLLAGEN |
ECM-Receptor |
KEGG: hsa04512 |
| Monocytes(Nos)_source |
COL6A1_ligand |
Monocytes(Nos)_target |
CD44_receptor |
9.640e-03 |
0.0 |
COLLAGEN |
ECM-Receptor |
KEGG: hsa04512 |
| CD8+,T-cells(Nos)_source |
ADGRE5_ligand |
HSC(Nos)_target |
CD55_receptor |
2.611e-04 |
0.0 |
ADGRE5 |
Cell-Cell Contact |
PMID: 11297558 |
| CD8+,T-cells(Nos)_source |
ADGRE5_ligand |
Monocytes(Nos)_target |
CD55_receptor |
7.620e-04 |
0.0 |
ADGRE5 |
Cell-Cell Contact |
PMID: 11297558 |
| Monocytes(Nos)_source |
ADGRE5_ligand |
Monocytes(Nos)_target |
CD55_receptor |
8.850e-03 |
0.0 |
ADGRE5 |
Cell-Cell Contact |
PMID: 11297558 |
| HSC(Nos)_source |
APP_ligand |
CD8+,T-cells(Nos)_target |
CD74_receptor |
3.567e-05 |
0.0 |
APP |
Cell-Cell Contact |
PMID: 19849849 |
| HSC(Nos)_source |
APP_ligand |
HSC(Nos)_target |
CD74_receptor |
5.161e-04 |
0.0 |
APP |
Cell-Cell Contact |
PMID: 19849849 |
| HSC(Nos)_source |
APP_ligand |
Monocytes(Nos)_target |
CD74_receptor |
1.239e-03 |
0.0 |
APP |
Cell-Cell Contact |
PMID: 19849849 |
| Monocytes(Nos)_source |
CD99_ligand |
HSC(Nos)_target |
CD99_receptor |
5.020e-02 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
CD99_ligand |
Monocytes(Nos)_target |
CD99_receptor |
5.020e-02 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
CD99_ligand |
Monocytes(Nos)_target |
CD99_receptor |
1.236e-01 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
MPZL1_ligand |
HSC(Nos)_target |
MPZL1_receptor |
3.182e-05 |
0.0 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
SEMA4D_ligand |
HSC(Nos)_target |
PLXNB2_receptor |
6.175e-06 |
0.0 |
SEMA4 |
Cell-Cell Contact |
PMID: 27533782 |
| HSC(Nos)_source |
SEMA4D_ligand |
HSC(Nos)_target |
PLXNB2_receptor |
1.963e-07 |
0.0 |
SEMA4 |
Cell-Cell Contact |
PMID: 27533782 |
| Monocytes(Nos)_source |
SEMA4D_ligand |
HSC(Nos)_target |
PLXNB2_receptor |
3.572e-07 |
0.0 |
SEMA4 |
Cell-Cell Contact |
PMID: 27533782 |
| CD8+,T-cells(Nos)_source |
SEMA4D_ligand |
Monocytes(Nos)_target |
PLXNB2_receptor |
5.003e-09 |
0.0 |
SEMA4 |
Cell-Cell Contact |
PMID: 27533782 |
| HSC(Nos)_source |
SEMA4D_ligand |
Monocytes(Nos)_target |
PLXNB2_receptor |
1.590e-10 |
0.0 |
SEMA4 |
Cell-Cell Contact |
PMID: 27533782 |
| CD8+,T-cells(Nos)_source |
SEMA4D_ligand |
HSC(Nos)_target |
CD72_receptor |
6.375e-05 |
0.0 |
SEMA4 |
Cell-Cell Contact |
PMID: 22325954 |
| HSC(Nos)_source |
SEMA4D_ligand |
HSC(Nos)_target |
CD72_receptor |
2.036e-06 |
0.0 |
SEMA4 |
Cell-Cell Contact |
PMID: 22325954 |
| Monocytes(Nos)_source |
SEMA4D_ligand |
HSC(Nos)_target |
CD72_receptor |
3.704e-06 |
0.0 |
SEMA4 |
Cell-Cell Contact |
PMID: 22325954 |
| CD8+,T-cells(Nos)_source |
SEMA4D_ligand |
Monocytes(Nos)_target |
CD72_receptor |
1.258e-04 |
0.0 |
SEMA4 |
Cell-Cell Contact |
PMID: 22325954 |
| HSC(Nos)_source |
SEMA4D_ligand |
Monocytes(Nos)_target |
CD72_receptor |
4.014e-06 |
0.0 |
SEMA4 |
Cell-Cell Contact |
PMID: 22325954 |