Sample overview
| Project Name |
TARGET-ALL
|
| GSE ID |
GSE196214
|
| GSM ID |
GSM5862853
|
| Cell Line |
None
|
| Tissue type |
Bone Marrow
|
| Disease Type |
Diagnosis
|
| PMID |
\
|
| Initial gene number |
33538
|
| Initial cell number |
5238
|
| Post-QC gene number |
7421
|
| Post-QC cell number |
5045
|
Bulk-to-ScRNA-seq Label Transfer
Bulk phenotype-associated subpopulations
Reference-Based Annotation
Differentially expressed genes
Overall Survival : Cluster
vs
There are no results of the analysis here
Overall Survival : Cluster
vs ( + )
There are no results of the analysis here
Clinical Stage : Cluster
vs
There
are no results of the analysis here
Tumor Size : Cluster
vs
There
are no results of the analysis here
Lymph Node Involvement : Cluster
vs
There
are no results of the analysis here
Distant Metastasis : Cluster
vs
There
are no results of the analysis here
Cell-Cell communications ( Survival-Associated Subpopulations Across Cell Types )
Cell Population Signaling and Communication
Ligand-Receptor-Mediated Cell-Cell Interactions
| Sending Cell Type |
Ligand |
Receiving Cell Type |
Receptor |
Score |
P-value |
Pathway Name |
Function |
Evidence |
| HSC(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CXCR4_receptor |
7.597e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| HSC(Nos)_source |
MIF_ligand |
HSC(Nos)_target |
CD74_CXCR4_receptor |
1.270e-02 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| HSC(Nos)_source |
MIF_ligand |
B-cells(Nos)_target |
CD74_CD44_receptor |
4.231e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| HSC(Nos)_source |
MIF_ligand |
HSC(Nos)_target |
CD74_CD44_receptor |
7.302e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| HSC(Nos)_source |
TNF_ligand |
HSC(Nos)_target |
TNFRSF1A_receptor |
2.075e-04 |
0.0 |
TNF |
Secreted Signaling |
KEGG: hsa04060 |
| HSC(Nos)_source |
TNF_ligand |
HSC(Nos)_target |
TNFRSF1B_receptor |
1.909e-05 |
0.0 |
TNF |
Secreted Signaling |
KEGG: hsa04060 |
| B-cells(Nos)_source |
LGALS9_ligand |
HSC(Nos)_target |
PTPRC_receptor |
1.445e-03 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| B-cells(Nos)_source |
ADGRE5_ligand |
HSC(Nos)_target |
CD55_receptor |
8.374e-04 |
0.0 |
ADGRE5 |
Cell-Cell Contact |
PMID: 11297558 |
| HSC(Nos)_source |
ADGRE5_ligand |
HSC(Nos)_target |
CD55_receptor |
1.555e-03 |
0.0 |
ADGRE5 |
Cell-Cell Contact |
PMID: 11297558 |
| HSC(Nos)_source |
APP_ligand |
B-cells(Nos)_target |
CD74_receptor |
1.995e-04 |
0.0 |
APP |
Cell-Cell Contact |
PMID: 19849849 |
| HSC(Nos)_source |
APP_ligand |
HSC(Nos)_target |
CD74_receptor |
3.561e-04 |
0.0 |
APP |
Cell-Cell Contact |
PMID: 19849849 |
| HSC(Nos)_source |
APP_ligand |
Monocytes(Nos)_target |
CD74_receptor |
1.300e-05 |
0.0 |
APP |
Cell-Cell Contact |
PMID: 19849849 |
| B-cells(Nos)_source |
CD22_ligand |
HSC(Nos)_target |
PTPRC_receptor |
5.592e-04 |
0.0 |
CD22 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
CD22_ligand |
HSC(Nos)_target |
PTPRC_receptor |
1.034e-03 |
0.02 |
CD22 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
PTPRC_ligand |
B-cells(Nos)_target |
CD22_receptor |
5.592e-04 |
0.0 |
CD45 |
Cell-Cell Contact |
PMID: 12115612 |
| HSC(Nos)_source |
PTPRC_ligand |
HSC(Nos)_target |
CD22_receptor |
1.034e-03 |
0.02 |
CD45 |
Cell-Cell Contact |
PMID: 12115612 |
| B-cells(Nos)_source |
CD99_ligand |
B-cells(Nos)_target |
CD99_receptor |
4.331e-02 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
CD99_ligand |
B-cells(Nos)_target |
CD99_receptor |
7.841e-02 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Nos)_source |
CD99_ligand |
HSC(Nos)_target |
CD99_receptor |
7.841e-02 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
ICAM2_ligand |
HSC(Nos)_target |
ITGAL_ITGB2_receptor |
2.487e-05 |
0.0 |
ICAM |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
ITGB2_ligand |
HSC(Nos)_target |
ICAM2_receptor |
6.505e-05 |
0.0 |
ITGB2 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
MPZL1_ligand |
HSC(Nos)_target |
MPZL1_receptor |
9.974e-05 |
0.0 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
PECAM1_ligand |
HSC(Nos)_target |
PECAM1_receptor |
4.899e-04 |
0.0 |
PECAM1 |
Cell-Cell Contact |
KEGG: hsa04514 |
| B-cells(Nos)_source |
SELL_ligand |
B-cells(Nos)_target |
CD34_receptor |
1.479e-03 |
0.0 |
SELL |
Cell-Cell Contact |
PMID: 7692600; PMID: 8977216 |
| HSC(Nos)_source |
SELL_ligand |
B-cells(Nos)_target |
CD34_receptor |
4.523e-03 |
0.0 |
SELL |
Cell-Cell Contact |
PMID: 7692600; PMID: 8977216 |
| B-cells(Nos)_source |
SELL_ligand |
HSC(Nos)_target |
CD34_receptor |
3.324e-03 |
0.0 |
SELL |
Cell-Cell Contact |
PMID: 7692600; PMID: 8977216 |
| HSC(Nos)_source |
SELL_ligand |
HSC(Nos)_target |
CD34_receptor |
1.015e-02 |
0.0 |
SELL |
Cell-Cell Contact |
PMID: 7692600; PMID: 8977216 |