Sample overview
| Project Name |
TARGET-ALL
|
| GSE ID |
GSE196214
|
| GSM ID |
GSM5862841
|
| Cell Line |
None
|
| Tissue type |
Bone Marrow
|
| Disease Type |
Diagnosis
|
| PMID |
\
|
| Initial gene number |
33538
|
| Initial cell number |
1516
|
| Post-QC gene number |
3781
|
| Post-QC cell number |
1366
|
Bulk-to-ScRNA-seq Label Transfer
Bulk phenotype-associated subpopulations
Reference-Based Annotation
Differentially expressed genes
Overall Survival : Cluster
vs
There are no results of the analysis here
Overall Survival : Cluster
vs ( + )
There are no results of the analysis here
Clinical Stage : Cluster
vs
There
are no results of the analysis here
Tumor Size : Cluster
vs
There
are no results of the analysis here
Lymph Node Involvement : Cluster
vs
There
are no results of the analysis here
Distant Metastasis : Cluster
vs
There
are no results of the analysis here
Cell-Cell communications ( Survival-Associated Subpopulations Across Cell Types )
Cell Population Signaling and Communication
Ligand-Receptor-Mediated Cell-Cell Interactions
| Sending Cell Type |
Ligand |
Receiving Cell Type |
Receptor |
Score |
P-value |
Pathway Name |
Function |
Evidence |
| CD8+,T-cells(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CXCR4_receptor |
1.349e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| HSC(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CXCR4_receptor |
4.496e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| Monocytes(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CXCR4_receptor |
4.387e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| HSC(Nos)_source |
MIF_ligand |
HSC(Nos)_target |
CD74_CD44_receptor |
1.344e-02 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| CD8+,T-cells(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
9.761e-04 |
0.02 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| HSC(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
3.288e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Monocytes(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
3.182e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| HSC(Nos)_source |
MDK_ligand |
HSC(Nos)_target |
ITGA4_ITGB1_receptor |
1.032e-02 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| HSC(Nos)_source |
MDK_ligand |
Monocytes(Nos)_target |
ITGA4_ITGB1_receptor |
1.171e-03 |
0.02 |
MK |
Secreted Signaling |
PMID: 28356350 |
| HSC(Nos)_source |
MDK_ligand |
CD8+,T-cells(Nos)_target |
NCL_receptor |
9.026e-03 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| HSC(Nos)_source |
MDK_ligand |
HSC(Nos)_target |
NCL_receptor |
2.165e-02 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| HSC(Nos)_source |
MDK_ligand |
Monocytes(Nos)_target |
NCL_receptor |
2.647e-03 |
0.0 |
MK |
Secreted Signaling |
PMID: 28356350 |
| HSC(Nos)_source |
LGALS9_ligand |
CD8+,T-cells(Nos)_target |
PTPRC_receptor |
7.806e-03 |
0.02 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| Monocytes(Nos)_source |
LGALS9_ligand |
CD8+,T-cells(Nos)_target |
PTPRC_receptor |
1.441e-03 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| HSC(Nos)_source |
LGALS9_ligand |
HSC(Nos)_target |
PTPRC_receptor |
1.548e-02 |
0.01 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| Monocytes(Nos)_source |
LGALS9_ligand |
HSC(Nos)_target |
PTPRC_receptor |
2.857e-03 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| HSC(Nos)_source |
LGALS9_ligand |
Monocytes(Nos)_target |
PTPRC_receptor |
2.232e-03 |
0.03 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| Monocytes(Nos)_source |
LGALS9_ligand |
Monocytes(Nos)_target |
PTPRC_receptor |
4.119e-04 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| HSC(Nos)_source |
CD99_ligand |
HSC(Nos)_target |
CD99_receptor |
1.411e-01 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
MPZL1_ligand |
HSC(Nos)_target |
MPZL1_receptor |
1.722e-04 |
0.0 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
MPZL1_ligand |
HSC(Nos)_target |
MPZL1_receptor |
2.483e-05 |
0.0 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
MPZL1_ligand |
Monocytes(Nos)_target |
MPZL1_receptor |
2.483e-05 |
0.0 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
PECAM1_ligand |
HSC(Nos)_target |
PECAM1_receptor |
6.428e-04 |
0.0 |
PECAM1 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
PECAM1_ligand |
HSC(Nos)_target |
PECAM1_receptor |
8.833e-05 |
0.0 |
PECAM1 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
PECAM1_ligand |
Monocytes(Nos)_target |
PECAM1_receptor |
8.833e-05 |
0.0 |
PECAM1 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
SELL_ligand |
HSC(Nos)_target |
CD34_receptor |
1.167e-02 |
0.0 |
SELL |
Cell-Cell Contact |
PMID: 7692600; PMID: 8977216 |
| CD8+,T-cells(Nos)_source |
SEMA4D_ligand |
HSC(Nos)_target |
PLXNB2_receptor |
9.294e-05 |
0.0 |
SEMA4 |
Cell-Cell Contact |
PMID: 27533782 |
| HSC(Nos)_source |
SEMA4D_ligand |
HSC(Nos)_target |
PLXNB2_receptor |
1.591e-04 |
0.0 |
SEMA4 |
Cell-Cell Contact |
PMID: 27533782 |
| Monocytes(Nos)_source |
SEMA4D_ligand |
HSC(Nos)_target |
PLXNB2_receptor |
3.292e-05 |
0.01 |
SEMA4 |
Cell-Cell Contact |
PMID: 27533782 |
| CD8+,T-cells(Nos)_source |
SEMA4D_ligand |
Monocytes(Nos)_target |
PLXNB2_receptor |
1.857e-05 |
0.0 |
SEMA4 |
Cell-Cell Contact |
PMID: 27533782 |
| HSC(Nos)_source |
SEMA4D_ligand |
Monocytes(Nos)_target |
PLXNB2_receptor |
3.179e-05 |
0.0 |
SEMA4 |
Cell-Cell Contact |
PMID: 27533782 |
| Monocytes(Nos)_source |
SEMA4D_ligand |
Monocytes(Nos)_target |
PLXNB2_receptor |
6.577e-06 |
0.0 |
SEMA4 |
Cell-Cell Contact |
PMID: 27533782 |