Sample overview
| Project Name |
TARGET-ALL
|
| GSE ID |
GSE196214
|
| GSM ID |
GSM5862818
|
| Cell Line |
None
|
| Tissue type |
Bone Marrow
|
| Disease Type |
Relapse
|
| PMID |
\
|
| Initial gene number |
33538
|
| Initial cell number |
3254
|
| Post-QC gene number |
4835
|
| Post-QC cell number |
2954
|
Bulk-to-ScRNA-seq Label Transfer
Bulk phenotype-associated subpopulations
Reference-Based Annotation
Differentially expressed genes
Overall Survival : Cluster
vs
There are no results of the analysis here
Overall Survival : Cluster
vs ( + )
There are no results of the analysis here
Clinical Stage : Cluster
vs
There
are no results of the analysis here
Tumor Size : Cluster
vs
There
are no results of the analysis here
Lymph Node Involvement : Cluster
vs
There
are no results of the analysis here
Distant Metastasis : Cluster
vs
There
are no results of the analysis here
Cell-Cell communications ( Survival-Associated Subpopulations Across Cell Types )
Cell Population Signaling and Communication
Ligand-Receptor-Mediated Cell-Cell Interactions
| Sending Cell Type |
Ligand |
Receiving Cell Type |
Receptor |
Score |
P-value |
Pathway Name |
Function |
Evidence |
| CD8+,T-cells(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CXCR4_receptor |
9.688e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| HSC(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CXCR4_receptor |
9.541e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| Monocytes(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CXCR4_receptor |
1.692e-04 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 24760155 |
| HSC(Nos)_source |
MIF_ligand |
CD8+,T-cells(Nos)_target |
CD74_CD44_receptor |
4.937e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| CD8+,T-cells(Nos)_source |
MIF_ligand |
HSC(Nos)_target |
CD74_CD44_receptor |
5.768e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| HSC(Nos)_source |
MIF_ligand |
HSC(Nos)_target |
CD74_CD44_receptor |
5.650e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| CD8+,T-cells(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
1.747e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| HSC(Nos)_source |
MIF_ligand |
Monocytes(Nos)_target |
CD74_CD44_receptor |
1.711e-03 |
0.0 |
MIF |
Secreted Signaling |
PMID: 29637711; PMID: 26175090 |
| Monocytes(Nos)_source |
NAMPT_ligand |
CD8+,T-cells(Nos)_target |
ITGA5_ITGB1_receptor |
4.921e-05 |
0.0 |
VISFATIN |
Secreted Signaling |
PMID: 28490838 |
| Monocytes(Nos)_source |
NAMPT_ligand |
Erythrocytes(Nos)_target |
ITGA5_ITGB1_receptor |
7.959e-06 |
0.0 |
VISFATIN |
Secreted Signaling |
PMID: 28490838 |
| Monocytes(Nos)_source |
NAMPT_ligand |
HSC(Nos)_target |
ITGA5_ITGB1_receptor |
1.097e-04 |
0.0 |
VISFATIN |
Secreted Signaling |
PMID: 28490838 |
| Monocytes(Nos)_source |
NAMPT_ligand |
Monocytes(Nos)_target |
ITGA5_ITGB1_receptor |
3.122e-05 |
0.0 |
VISFATIN |
Secreted Signaling |
PMID: 28490838 |
| HSC(Nos)_source |
CTSG_ligand |
CD8+,T-cells(Nos)_target |
F2R_receptor |
2.535e-07 |
0.0 |
PARs |
Secreted Signaling |
KEGG: hsa04080 |
| HSC(Nos)_source |
CTSG_ligand |
HSC(Nos)_target |
F2R_receptor |
1.902e-04 |
0.0 |
PARs |
Secreted Signaling |
KEGG: hsa04080 |
| HSC(Nos)_source |
CTSG_ligand |
Monocytes(Nos)_target |
F2R_receptor |
4.412e-08 |
0.0 |
PARs |
Secreted Signaling |
KEGG: hsa04080 |
| HSC(Nos)_source |
GZMA_ligand |
CD8+,T-cells(Nos)_target |
F2R_receptor |
1.057e-07 |
0.0 |
PARs |
Secreted Signaling |
KEGG: hsa04080 |
| HSC(Nos)_source |
GZMA_ligand |
Erythrocytes(Nos)_target |
F2R_receptor |
6.406e-09 |
0.0 |
PARs |
Secreted Signaling |
KEGG: hsa04080 |
| HSC(Nos)_source |
GZMA_ligand |
HSC(Nos)_target |
F2R_receptor |
7.941e-05 |
0.0 |
PARs |
Secreted Signaling |
KEGG: hsa04080 |
| HSC(Nos)_source |
GZMA_ligand |
Monocytes(Nos)_target |
F2R_receptor |
1.840e-08 |
0.0 |
PARs |
Secreted Signaling |
KEGG: hsa04080 |
| HSC(Nos)_source |
LGALS9_ligand |
CD8+,T-cells(Nos)_target |
PTPRC_receptor |
5.421e-03 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| Monocytes(Nos)_source |
LGALS9_ligand |
CD8+,T-cells(Nos)_target |
PTPRC_receptor |
9.267e-04 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| HSC(Nos)_source |
LGALS9_ligand |
HSC(Nos)_target |
PTPRC_receptor |
3.155e-03 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| Monocytes(Nos)_source |
LGALS9_ligand |
HSC(Nos)_target |
PTPRC_receptor |
5.378e-04 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| HSC(Nos)_source |
LGALS9_ligand |
Monocytes(Nos)_target |
PTPRC_receptor |
1.004e-03 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| Monocytes(Nos)_source |
LGALS9_ligand |
Monocytes(Nos)_target |
PTPRC_receptor |
1.712e-04 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 30120235 |
| HSC(Nos)_source |
LGALS9_ligand |
CD8+,T-cells(Nos)_target |
CD44_receptor |
2.722e-03 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| Monocytes(Nos)_source |
LGALS9_ligand |
CD8+,T-cells(Nos)_target |
CD44_receptor |
4.621e-04 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| HSC(Nos)_source |
LGALS9_ligand |
HSC(Nos)_target |
CD44_receptor |
2.734e-03 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| Monocytes(Nos)_source |
LGALS9_ligand |
HSC(Nos)_target |
CD44_receptor |
4.654e-04 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| HSC(Nos)_source |
LGALS9_ligand |
Monocytes(Nos)_target |
CD44_receptor |
6.579e-04 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| Monocytes(Nos)_source |
LGALS9_ligand |
Monocytes(Nos)_target |
CD44_receptor |
1.118e-04 |
0.0 |
GALECTIN |
Secreted Signaling |
PMID: 25065622 |
| CD8+,T-cells(Nos)_source |
ADGRE5_ligand |
HSC(Nos)_target |
CD55_receptor |
2.887e-04 |
0.01 |
ADGRE5 |
Cell-Cell Contact |
PMID: 11297558 |
| Monocytes(Nos)_source |
ADGRE5_ligand |
HSC(Nos)_target |
CD55_receptor |
6.169e-05 |
0.04 |
ADGRE5 |
Cell-Cell Contact |
PMID: 11297558 |
| CD8+,T-cells(Nos)_source |
ADGRE5_ligand |
Monocytes(Nos)_target |
CD55_receptor |
1.596e-04 |
0.0 |
ADGRE5 |
Cell-Cell Contact |
PMID: 11297558 |
| HSC(Nos)_source |
ADGRE5_ligand |
Monocytes(Nos)_target |
CD55_receptor |
7.847e-05 |
0.0 |
ADGRE5 |
Cell-Cell Contact |
PMID: 11297558 |
| Monocytes(Nos)_source |
ADGRE5_ligand |
Monocytes(Nos)_target |
CD55_receptor |
3.410e-05 |
0.0 |
ADGRE5 |
Cell-Cell Contact |
PMID: 11297558 |
| HSC(Nos)_source |
CD99_ligand |
CD8+,T-cells(Nos)_target |
CD99_receptor |
2.338e-02 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
CD99_ligand |
HSC(Nos)_target |
CD99_receptor |
2.338e-02 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
CD99_ligand |
HSC(Nos)_target |
CD99_receptor |
2.222e-02 |
0.0 |
CD99 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
MPZL1_ligand |
CD8+,T-cells(Nos)_target |
MPZL1_receptor |
3.972e-07 |
0.0 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
MPZL1_ligand |
Erythrocytes(Nos)_target |
MPZL1_receptor |
2.059e-08 |
0.0 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
MPZL1_ligand |
HSC(Nos)_target |
MPZL1_receptor |
3.972e-07 |
0.0 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| Erythrocytes(Nos)_source |
MPZL1_ligand |
HSC(Nos)_target |
MPZL1_receptor |
2.059e-08 |
0.0 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
MPZL1_ligand |
HSC(Nos)_target |
MPZL1_receptor |
3.908e-05 |
0.0 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
MPZL1_ligand |
HSC(Nos)_target |
MPZL1_receptor |
1.040e-07 |
0.0 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
MPZL1_ligand |
Monocytes(Nos)_target |
MPZL1_receptor |
1.040e-07 |
0.0 |
MPZ |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
PECAM1_ligand |
HSC(Nos)_target |
PECAM1_receptor |
3.275e-04 |
0.0 |
PECAM1 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
PECAM1_ligand |
HSC(Nos)_target |
PECAM1_receptor |
9.368e-05 |
0.0 |
PECAM1 |
Cell-Cell Contact |
KEGG: hsa04514 |
| HSC(Nos)_source |
PECAM1_ligand |
Monocytes(Nos)_target |
PECAM1_receptor |
9.368e-05 |
0.0 |
PECAM1 |
Cell-Cell Contact |
KEGG: hsa04514 |
| Monocytes(Nos)_source |
PECAM1_ligand |
Monocytes(Nos)_target |
PECAM1_receptor |
2.680e-05 |
0.0 |
PECAM1 |
Cell-Cell Contact |
KEGG: hsa04514 |
| CD8+,T-cells(Nos)_source |
SELL_ligand |
HSC(Nos)_target |
CD34_receptor |
1.438e-03 |
0.0 |
SELL |
Cell-Cell Contact |
PMID: 7692600; PMID: 8977216 |
| HSC(Nos)_source |
SELL_ligand |
HSC(Nos)_target |
CD34_receptor |
1.959e-03 |
0.0 |
SELL |
Cell-Cell Contact |
PMID: 7692600; PMID: 8977216 |